JPH0610129B2 - Cosmetics for hair - Google Patents
Cosmetics for hairInfo
- Publication number
- JPH0610129B2 JPH0610129B2 JP62275010A JP27501087A JPH0610129B2 JP H0610129 B2 JPH0610129 B2 JP H0610129B2 JP 62275010 A JP62275010 A JP 62275010A JP 27501087 A JP27501087 A JP 27501087A JP H0610129 B2 JPH0610129 B2 JP H0610129B2
- Authority
- JP
- Japan
- Prior art keywords
- hair
- effect
- benzoic acid
- hinokitiol
- dandruff
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000002537 cosmetic Substances 0.000 title claims description 6
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 claims description 20
- FUWUEFKEXZQKKA-UHFFFAOYSA-N beta-thujaplicin Chemical compound CC(C)C=1C=CC=C(O)C(=O)C=1 FUWUEFKEXZQKKA-UHFFFAOYSA-N 0.000 claims description 18
- 239000005711 Benzoic acid Substances 0.000 claims description 10
- 241000378467 Melaleuca Species 0.000 claims description 10
- 235000010233 benzoic acid Nutrition 0.000 claims description 10
- TUFYVOCKVJOUIR-UHFFFAOYSA-N alpha-Thujaplicin Natural products CC(C)C=1C=CC=CC(=O)C=1O TUFYVOCKVJOUIR-UHFFFAOYSA-N 0.000 claims description 9
- 229930007845 β-thujaplicin Natural products 0.000 claims description 9
- 239000000203 mixture Substances 0.000 claims description 5
- 230000000694 effects Effects 0.000 description 12
- 230000000844 anti-bacterial effect Effects 0.000 description 9
- 208000001840 Dandruff Diseases 0.000 description 8
- 241000555688 Malassezia furfur Species 0.000 description 6
- 230000000052 comparative effect Effects 0.000 description 3
- 230000005764 inhibitory process Effects 0.000 description 3
- 210000004761 scalp Anatomy 0.000 description 3
- 229940043810 zinc pyrithione Drugs 0.000 description 3
- PICXIOQBANWBIZ-UHFFFAOYSA-N zinc;1-oxidopyridine-2-thione Chemical group [Zn+2].[O-]N1C=CC=CC1=S.[O-]N1C=CC=CC1=S PICXIOQBANWBIZ-UHFFFAOYSA-N 0.000 description 3
- 241000894006 Bacteria Species 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- 208000003251 Pruritus Diseases 0.000 description 2
- 239000003242 anti bacterial agent Substances 0.000 description 2
- 239000003899 bactericide agent Substances 0.000 description 2
- 230000009036 growth inhibition Effects 0.000 description 2
- 210000001732 sebaceous gland Anatomy 0.000 description 2
- 230000028327 secretion Effects 0.000 description 2
- 239000002453 shampoo Substances 0.000 description 2
- 238000009395 breeding Methods 0.000 description 1
- 230000001488 breeding effect Effects 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 239000006071 cream Substances 0.000 description 1
- 239000000839 emulsion Substances 0.000 description 1
- 210000002615 epidermis Anatomy 0.000 description 1
- 230000029142 excretion Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000003676 hair preparation Substances 0.000 description 1
- 239000008266 hair spray Substances 0.000 description 1
- 230000005722 itchiness Effects 0.000 description 1
- 239000002609 medium Substances 0.000 description 1
- 230000000116 mitigating effect Effects 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 239000001965 potato dextrose agar Substances 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 238000004062 sedimentation Methods 0.000 description 1
- 244000005714 skin microbiome Species 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 210000000106 sweat gland Anatomy 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 230000001256 tonic effect Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/35—Ketones, e.g. benzophenone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/368—Carboxylic acids; Salts or anhydrides thereof with carboxyl groups directly bound to carbon atoms of aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/006—Antidandruff preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/02—Preparations for cleaning the hair
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Cosmetics (AREA)
Description
【発明の詳細な説明】 《産業上の利用分野》 本発明は、優れた抗フケ効果を有する頭髪用化粧料に関
する。更に詳しくは、安息香酸とヒノキチオール及び／
又はメラレウカオイル（オーストラリア原産Melaleuca
alternifoliaの精油）を含有することにより、細菌、特
にフケの原因となるといわれているピチロスポラム オ
バール Pityrosporum ovaleに対する抗菌作用を有する化合物を
配合してなる頭髪用化粧料に関する。TECHNICAL FIELD The present invention relates to a hair cosmetic composition having an excellent anti-dandruff effect. More specifically, benzoic acid and hinokitiol and /
Or Melaleuca oil (Melaleuca native to Australia
The present invention relates to a hair cosmetic composition containing a compound having an antibacterial action against bacteria, particularly Pityrosporum ovale, which is said to cause bacteria, especially dandruff.
《従来の技術》 一般に、フケは皮脂腺の分泌物・汗腺の分泌物・表皮層
の剥離物等からなり、通常は皮脂腺等の分泌昴進により
発生し、また皮膚の細菌、特にPityrosporum ovaleの繁
殖により、助長されるといわれている。このため従来か
ら抗菌剤・殺菌剤を添加した頭髪用化粧料がフケ防止の
ために使用されていた。中でも最も有効とされているも
のはジンクピリチオンである。また、安息香酸、ヒノキ
チオール、メラレウカオイルにも一般に抗菌力・殺菌力
があることは知られている。<Prior art> In general, dandruff consists of secretions of sebaceous glands, secretions of sweat glands, exfoliated substances of the epidermal layer, etc., which are usually caused by excretion of sebaceous glands, etc., and breeding of skin bacteria, especially Pityrosporum ovale. It is said that it will be promoted by. Therefore, hair cosmetics containing antibacterial agents and bactericides have been conventionally used for the prevention of dandruff. The most effective of these is zinc pyrithione. It is also known that benzoic acid, hinokitiol, and melaleuca oil generally have antibacterial and bactericidal activities.
《発明が解決しようとする問題点》 しかしながら、安息香酸、ヒノキチオール、メラレウカ
オイルなどの抗菌剤・殺菌剤は安全性の問題から、充分
な効果を示す濃度での使用は避けることが好ましい。ま
た、ジンクピリチオンは水、エタノールにほとんど溶け
ないため、沈降などの問題があり、低粘度の製品に配合
することは困難である。<< Problems to be Solved by the Invention >> However, it is preferable to avoid the use of an antibacterial agent / bactericidal agent such as benzoic acid, hinokitiol, and melaleuca oil at a concentration showing a sufficient effect from the viewpoint of safety. Further, since zinc pyrithione is almost insoluble in water and ethanol, there is a problem such as sedimentation, and it is difficult to mix it into a product having a low viscosity.
《問題点を解決するための手段》 本発明者らは、上記事情に鑑み鋭意研究を重ねた結果、
安息香酸と、ヒノキチオール及び／又はメラレウカオイ
ルの混合物がPityrosporum ovaleに対し強い抗菌力を示
し、かつ安全性も高いことを発見し、本発明を完成させ
るに至つた。<< Means for Solving Problems >> The present inventors have conducted extensive studies in view of the above circumstances, and as a result,
The inventors have found that a mixture of benzoic acid and hinokitiol and / or melaleuca oil exhibits strong antibacterial activity against Pityrosporum ovale and has high safety, and completed the present invention.
すなわち本発明は、 安息香酸とヒノキチオール 安息香酸とメラレウカオイル 安息香酸とヒノキチオールとメラレウカオイルのいず
れかの組合せを配合した強い抗菌・殺菌作用をもち、か
つ安全性の高い頭髪用化粧料に関する。That is, the present invention relates to a highly safe cosmetic composition for hair that has a strong antibacterial / bactericidal action and is highly safe, which contains any combination of benzoic acid, hinokitiol, benzoic acid, and melaleuca oil, benzoic acid, hinokitiol, and melaleuca oil.
配合量は、特に限定されないが、抗菌・殺菌作用と安全
性を考慮すると、安息香酸0.001〜1.0重量％、ヒノキチ
オール0.001〜1.0重量％、メラレウカオイル0.01〜2.0
重量％、総量で0.01〜3.0重量％程度が望ましい。The blending amount is not particularly limited, but considering antibacterial / bactericidal action and safety, benzoic acid 0.001 to 1.0% by weight, hinokitiol 0.001 to 1.0% by weight, Melaleuca oil 0.01 to 2.0
The total amount is preferably 0.01 to 3.0% by weight.
本発明の頭髪用化粧料とは、頭皮または頭髪に使用する
ものを広く指し、ヘアシヤンプー、ヘアリンス、ヘアト
ニツク、頭皮用乳液など頭皮に直接塗布または、洗浄に
使用するものだけでなく、ヘアリキツド、ヘアクリー
ム、ヘアスプレー等の整髪料等も含有する。The cosmetics for hair of the present invention broadly refers to those used for the scalp or hair, and is not limited to those used for cleaning or directly applying to the scalp such as hair shampoo, hair rinse, hair tonic, scalp emulsion, and hair lick, hair. It also contains hair styling products such as cream and hair spray.
次に実験例および実施例を挙げて本発明を更に詳細に説
明する。Next, the present invention will be described in more detail with reference to experimental examples and examples.
〔実施例１〕 Pityrosporum ovale生育阻害実験 ポテトデキストロース寒天培地上にPityrosporum ovale
懸濁液を２００ul／plate塗抹し、plate中心部にペーパ
ーデイスク（φ１０mm）を置き、デイスク上に検体をul
スポツトし、検体によるPityrosporum ovale生育阻害距
離を測定し、結果を表−１に示した。[Example 1] Pityrosporum ovale growth inhibition experiment Pityrosporum ovale was grown on potato dextrose agar medium.
200ul / plate of the suspension is smeared, a paper disk (φ10mm) is placed in the center of the plate, and the sample is ul on the disk.
The Pityrosporum ovale growth inhibition distance was measured by spotting, and the results are shown in Table 1.
阻害距離は、次の式により求めた。The inhibition distance was calculated by the following formula.
阻害距離（mm）＝（阻害円直径）−（ペーパーデイスク
直径） この表より安息香酸とヒノキチオール又はメラレウカオ
イルを組み合すと相乗効果により、低濃度で充分な効果
が発揮されることが明らかとなつた。Inhibition distance (mm) = (inhibition circle diameter)-(paper disk diameter) From this table, it was revealed that the combination of benzoic acid and hinokitiol or Melaleuca oil exerts a sufficient effect at a low concentration due to the synergistic effect.
〔実施例１〕 ヘアートニツク フケ防止効果 表−２の実施例１と比較例１を無作為に押出した各３０
名の男性パネラーに配布し、２週間使用させた。フケ防
止効果をパネラーの申告により評価し、結果を表−３に
示した。Example 1 Heart Nick Anti-dandruff effect 30 each of Example 1 and Comparative Example 1 shown in Table 2 were randomly extruded.
It was distributed to male panelists of the same name and used for 2 weeks. The antidandruff effect was evaluated by the panelists' results, and the results are shown in Table-3.
表−３において、実施例を用いた場合は、比較例を用い
た場合より明らかにフケ防止効果が認められる。 In Table 3, when the example is used, the antidandruff effect is clearly recognized as compared with the case where the comparative example is used.
〔実施例２〕 ヘアーシヤンプー フケ防止効果およびかゆみ止め効果 表−４の実施例２と比較例２，３を無作為に選出した各
２０名のパネラーに配布し、２週間使用させた。フケ防
止効果及びかゆみに対する効果は、パネラーの申告によ
り評価し、表−５及び表−６に示した。[Example 2] Hairshampoo Anti-dandruff effect and anti-itch effect Example 2 of Table 4 and Comparative Examples 2 and 3 were distributed to 20 randomly selected panelists and used for 2 weeks. The anti-dandruff effect and the effect on itch were evaluated by the panelists and shown in Table-5 and Table-6.
表−５及び表−６より本発明の実施例は従来最も有効で
あるとされていたジンクピリチオン配合のヘアーシヤン
プーと同等のフケ防止効果とかゆみに対する緩和作用を
もつていることが明らかとなつた。 From Table-5 and Table-6, it was revealed that the examples of the present invention have the same anti-dandruff effect and mitigation effect against itchiness as hair shampoo containing zinc pyrithione, which has been considered to be most effective in the past.
Claims (1)
ラレウカオイルを配合した頭髪用化粧料1. A hair cosmetic composition containing benzoic acid and hinokitiol and / or melaleuca oil.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP62275010A JPH0610129B2 (en) | 1987-10-29 | 1987-10-29 | Cosmetics for hair |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP62275010A JPH0610129B2 (en) | 1987-10-29 | 1987-10-29 | Cosmetics for hair |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH01117820A JPH01117820A (en) | 1989-05-10 |
| JPH0610129B2 true JPH0610129B2 (en) | 1994-02-09 |
Family
ID=17549625
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP62275010A Expired - Fee Related JPH0610129B2 (en) | 1987-10-29 | 1987-10-29 | Cosmetics for hair |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH0610129B2 (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100197543B1 (en) * | 1990-09-14 | 1999-06-15 | 오쓰까 아끼히꼬 | Detergent composition |
| JP2655011B2 (en) * | 1990-09-14 | 1997-09-17 | 大塚製薬株式会社 | Detergent composition |
| JPH06135821A (en) * | 1992-10-30 | 1994-05-17 | Kanebo Ltd | Hair tonic |
| KR100517553B1 (en) * | 1998-08-25 | 2006-02-17 | 주식회사 태평양 | Hair-care codmetic composition having dandruff formation-suppressing effect |
| FR2821746B1 (en) * | 2001-03-12 | 2004-12-03 | Oreal | USE OF COMPLEXES FORMED BY THE ASSOCIATION OF A TROPOLONE DERIVATIVE AND A DIVALENT METAL SALT AS AGENTS FOR THE CONTROL OF DESQUAMATIVE CONDITIONS OF SCALP |
| WO2006020190A1 (en) * | 2004-07-16 | 2006-02-23 | Richard Plymale | Dentifrice composition |
-
1987
- 1987-10-29 JP JP62275010A patent/JPH0610129B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JPH01117820A (en) | 1989-05-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| LAPS | Cancellation because of no payment of annual fees |