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JPH0575728B2 - - Google Patents

Info

Publication number
JPH0575728B2
JPH0575728B2 JP4155087A JP4155087A JPH0575728B2 JP H0575728 B2 JPH0575728 B2 JP H0575728B2 JP 4155087 A JP4155087 A JP 4155087A JP 4155087 A JP4155087 A JP 4155087A JP H0575728 B2 JPH0575728 B2 JP H0575728B2
Authority
JP
Japan
Prior art keywords
platelet aggregation
present
pyrazine
pyrazine derivative
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP4155087A
Other languages
English (en)
Japanese (ja)
Other versions
JPS63208520A (ja
Inventor
Toshio Wakabayashi
Akihiro Oota
Yasuo Akita
Norihiro Watanabe
Hirokazu Hasegawa
Michifumi Yaguchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Terumo Corp
Original Assignee
Terumo Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Terumo Corp filed Critical Terumo Corp
Priority to JP4155087A priority Critical patent/JPS63208520A/ja
Publication of JPS63208520A publication Critical patent/JPS63208520A/ja
Publication of JPH0575728B2 publication Critical patent/JPH0575728B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP4155087A 1987-02-26 1987-02-26 ピラジン誘導体を含有する血小板凝集抑制剤 Granted JPS63208520A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP4155087A JPS63208520A (ja) 1987-02-26 1987-02-26 ピラジン誘導体を含有する血小板凝集抑制剤

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP4155087A JPS63208520A (ja) 1987-02-26 1987-02-26 ピラジン誘導体を含有する血小板凝集抑制剤

Publications (2)

Publication Number Publication Date
JPS63208520A JPS63208520A (ja) 1988-08-30
JPH0575728B2 true JPH0575728B2 (da) 1993-10-21

Family

ID=12611534

Family Applications (1)

Application Number Title Priority Date Filing Date
JP4155087A Granted JPS63208520A (ja) 1987-02-26 1987-02-26 ピラジン誘導体を含有する血小板凝集抑制剤

Country Status (1)

Country Link
JP (1) JPS63208520A (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RS56995B1 (sr) 2008-12-19 2018-05-31 Vertex Pharma Derivati pirazina korisni kao inhibitori atr kinaze
US9334244B2 (en) 2010-05-12 2016-05-10 Vertex Pharmaceuticals Incorporated Compounds useful as inhibitors of ATR kinase
JP5836367B2 (ja) 2010-05-12 2015-12-24 バーテックス ファーマシューティカルズ インコーポレイテッドＶｅｒｔｅｘ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃｏｒｐｏｒａｔｅｄ Ａｔｒキナーゼ阻害剤として有用な化合物
AU2012315615A1 (en) 2011-09-30 2014-04-17 Vertex Pharmaceuticals Incorporated Processes for making compounds useful as inhibitors of ATR kinase
CN108464983A (zh) 2011-09-30 2018-08-31 沃泰克斯药物股份有限公司 用atr抑制剂治疗胰腺癌和非小细胞肺癌
DK2833973T3 (da) 2012-04-05 2018-01-02 Vertex Pharma Forbindelser, der er anvendelige som ATR-kinaseinhibitorer og kombinationsterapier deraf
EP2904406B1 (en) 2012-10-04 2018-03-21 Vertex Pharmaceuticals Incorporated Method for measuring atr inhibition mediated increases in dna damage
MX395066B (es) 2015-09-30 2025-03-24 Vertex Pharma Método para tratar cáncer usando una combinación de agentes que dañan el adn e inhibidores de proteína relacionada con ataxia telangiectasia y rad3 (atr).

Also Published As

Publication number Publication date
JPS63208520A (ja) 1988-08-30

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