JPH05286804A - Suspension preparation - Google Patents

Abstract

PURPOSE:To obtain the subject oil in water type suspension preparation by emulsifying or suspending an agriculturally and horticulturally active oily component without using an organic solvent as a base agent. CONSTITUTION:This suspension preparation contains (a) an agriculturally and horticulturally active oily component, (b) fine powder of a 2:1-structured clay mineral having 0.5 to 50mum particle size distribution, e.g. fine powder of montmorillonite, (c) a nonionic surfactant of HLB=4 to 7, (d) a nonionic surfactant of HLB=8 to 20 and (e) water. This suspension preparation exhibits a viscosity as low as 20 to 300 cps and an excellent suspension stability in water even when being diluted. This suspension preparation is also excellent in long- term stability.

Description

Detailed Description of the Invention

[0001]

FIELD OF THE INVENTION The present invention relates to a novel suspension containing an oily agricultural and horticultural active ingredient, and in particular, emulsifying the oily agricultural and horticultural active ingredient without using an organic solvent as a base,
The present invention relates to a novel oil-in-water type suspension prepared by suspending.

[0002]

2. Description of the Related Art As a preparation containing an oily active ingredient for agricultural and horticultural use, a preparation in the form of (1) emulsion or (2) wettable powder is known as a high content preparation used for diluting and spraying.

The conventional emulsion-form preparation of the above (1) contains a large amount of an organic solvent as a base, and therefore has a problem in transportation or storage from the viewpoint of "flammability of the organic solvent". From the viewpoint of "toxicity of organic solvent", there are problems such as safety problems for workers and other animals at the time of spraying, environmental problems, and chemical damage to crops.

Further, xylene, which has been frequently used,
Solvents such as toluene are used in EPA (Environmental Protec
2) of the Action Agency list “Fed.Reg., Vol.52, No.7
7, 13305 (1987) ”and is subject to the regulation of use in the future. Therefore, the development of the above-mentioned formulation without using an organic solvent as a base is desired. Also, above
The wettable powder form of (2) has drawbacks such as powdering when diluted for spraying and inconvenience in handling.

In order to solve the above problems and drawbacks, an organic solvent is not used as a base, water is used as a base instead of the solvent,
It has been proposed to prepare a preparation in which an oily active ingredient for agriculture and horticulture (a liquid mixture with an organic solvent that dissolves this active ingredient, if necessary) is dispersed in the form of fine particles, that is, an oil-in-water suspension. By making this oil-in-water form, it can be made into a non-dangerous substance, and since this oil-in-water suspension is liquid, when diluted with water and sprayed, it will be treated as a conventional emulsion form preparation. Similarly, quantitative handling is possible.

However, in the above oil-in-water suspension in which the active ingredient is oily, after a long time after the preparation, the particles of the active ingredient once dispersed are coalesced or the aqueous phase is separated, so that the preparation is physically stable. It causes various problems regarding sex.

[0007] As a means for solving the above-mentioned problems relating to physical stability, it has been usually dealt with by adding a thickener or the like to the dispersion medium. As typical thickeners, xanthan gum, tragacanth gum, xanthan gum, gum arabic, sodium carboxymethyl cellulose, hydroxyethyl cellulose, methyl cellulose, polyvinyl alcohol and the like have been conventionally used.

The stability of the preparation is improved by adding the above-mentioned thickener to the dispersion medium to thicken the dispersion medium. However, in order to stabilize the preparation for a long period of time, 500-1000 cps.
Alternatively, it is necessary to make the formulation viscosity higher, and at such a high viscosity, there is a problem in that the fluidity deteriorates, which makes it difficult to discharge from the container. Also,
Dispersibility in water when diluted with water is also poor, and it takes a long time to prepare a diluted spray solution, and it is difficult to handle.

On the contrary, in order to obtain a formulation having good dispersibility in water, the viscosity must be low, in which case the stability of the formulation becomes insufficient. As described above, the improvement of the stability of the preparation and the improvement of the dispersibility in water at the time of dilution are contradictory factors. Therefore, it is more preferable not to thicken the dispersion medium.

As a means for solving this problem, it has been conventionally proposed to add an anti-agglomeration agent for oil droplets (insoluble solid fine particles). For example, JP-A-2-306903 and JP-A-57-16940
6, JP-A-1-319402, etc. exist, and as a foreign patent, 1
There is French patent 1,604,687 in 972. In addition, (1) In order to uniformly decompose the poorly water-soluble pesticide raw material in water and improve storage stability, a suspension obtained by adding a surfactant and colloidal hydrous aluminum silicate fine powder to this pesticide raw material Agricultural chemical spraying agent (JP-A-51-79729), (2) Montmorillonite group clay mineral, and a pesticide composition in which a bactericidal or insecticidal component is stably interposed between interlayer lattices of the clay mineral (JP-A-SHO-60)
-142902), (3) Pesticide composition in suspension containing a poorly water-soluble pesticide active ingredient, particulate aluminum oxide, and bentonite mineral substance (JP-A-1-258603), (4) A poorly water-soluble pesticide active ingredient, and a surfactant. , A smectite-based clay mineral, and a pesticidal composition in water containing water (JP-A-1-283201).

[0011]

However, in the conventional preparations to which the anti-agglomeration agent for oil droplets (insoluble solid fine particles) is added, and also in the above-mentioned (1) to (4), low viscosity In addition, an oil-in-water suspension having good dispersibility in water when diluted and having good formulation stability for a long time has not been obtained.

The present inventors have prepared a suspension containing an oily active ingredient for agricultural and horticultural use by adding various insoluble solid fine particles to prepare various preparations, which have the above-mentioned superior effects as an anti-aggregation agent. As a result of extensive studies on fine particles, it was found that a suspension having low viscosity but excellent stability of the formulation and good dispersibility in water when diluted was obtained, and thus the present invention was completed. is there. That is, the technical problem (object) of the present invention is an oil-in-water type suspension containing an oily active ingredient for agricultural and horticultural use, having a low viscosity, good dispersibility in water even when diluted, and, Another object of the present invention is to provide the above-mentioned suspension having good formulation stability for a long period of time.

[0013]

The present invention is characterized in that a specific 2: 1 structural type clay mineral fine powder is used as insoluble solid fine particles, and a nonionic surfactant having a different HLB is used in combination. By this, the above-mentioned technical object which is the object of the present invention has been achieved.

That is, the present invention provides (a) an oily active ingredient for agricultural and horticultural use, (b) a 2: 1 structure type clay mineral fine powder having a particle size distribution of 0.5 to 50 μm, and (c) a nonionic surfactant of HLB 4 to 7. Agent, (d)
A suspension agent characterized by containing a nonionic surfactant of HLB 8 to 20 and (e) water.

The present invention will be described in detail below. As the oily active ingredient for agricultural and horticultural use which can be used in the suspension of the present invention,
It is a mixture containing one or more liquid mixture of an oily active ingredient for agricultural and horticultural use and, if necessary, an organic solvent in which this active ingredient is dissolved. As the solvent, it is possible to use any solvent capable of dissolving the oily agricultural and horticultural active ingredient, in order to stabilize the emulsified state with water, as described in detail later, hydrophobic and non-volatile Are preferred. For example, it is preferable to use a commercially available aromatic or aliphatic hydrocarbon solvent.

The oily active ingredient for agricultural and horticultural use used in the present invention is not particularly limited, but examples thereof include insecticides, fungicides and herbicides. As a few examples of these pesticides, specific examples of the pesticides (oil active ingredients for agricultural and horticultural use) are listed below, including their solubility and melting points. In the solubility (ppm, water) section, “g” is the number of grams in 1 liter of solvent, “%” represents the weight% in the solvent, and “M” represents “mixed” and “mixed”. "SS" is "slightly soluble", "IS" is "insoluble", "RT" is "room temperature (15-25
° C) ".

-Insecticide- (Carbamate type) Solubility (ppm, water) Melting point (° C) PHC, propoxur 2000/20 ° C 84-87 MIPC, isoprocarb (SS) 88-93 BPMC, Fenobucarb (SS) 32 MPMC, xylylcarb (xylylcarb) 580/20 ° C 71-78 MTMC, metolcarb 2600/30 ° C 76-77 XMC, “IS” 99 ethiofencarb 1900/20 ° C 33.4 NAC, Carbaryl 40/30 ℃ 142 Pirimicarb 2700/25 ℃ 90.5 Bendiocarb 40 129-130 Carbofuran 700 150-152 Furathiocarb “IS” Liquid Carbosulfan 0.3 liquid Benfuracarb 8 liquid

(Others) Bensultap 0.7-0.8 83-84 Buprofezin 0.9 / 25 ° C 106 Flufenoxuron 0.003 / 22 ° C 169-172 Diflubenzuron 0.2 / 20 ° C 210-230 Chlorine Fluazuron 0.016 / 25 ℃ 222〜223

(Synthetic pyrethroid type) Cyfluthrin (cyfluthrin) 1-2 μg liquid permethrin <0.1 34-39 cypermethrin 0.0087 / 25 ° C. 83.2 cyhalothrin 0.003 / 20 ° C. liquid fenpropathrin Fenvalerate <20 liquid flucythrinate 0.5 fluvalinate 0.002 liquid ethofenprox <0.001 36.4-37 cycloprothrin 0.091 / 25 ° C liquid resmethrin 1 <43-48 Allethrin 500 liquid

(Organophosphorus) MPP, fenthion 54-56 / RT solution MEP, fenitrothion (fenitrothion) 14/30 ° C solution propaphos (propaphos) 125 solution cyanophos 46 14-15 prothiophos (prothiofos) 1.7 / 20 ℃ liquid sulprofos <5 liquids profenofos 20/20 ° C liquid EPN “IS” 36 cyanofenphos 0.6 / 30 ° C 83 ethylthiomethone (disulfoton) 25 liquid thiometon 200/25 ° C Liquid PAP, phenthoate 11/24 ℃ Liquid marathon (malation) 145 / RT 2.85 Pyraclofos 33 liquid BRP, Nared “IS” 26 CVP, Chlorfenvinphos 145/23 ℃- 19 (-23) CVMP, tetrachlorvinphos 11/20 ℃ 97〜98 monocrotophos “M” 54〜55 phosalone 10 / RT 48 Chlorpyrifos-methyl 4/24 ℃ 45.5〜46 Chlorpyrifos 2/35 ℃ 42.5〜43 Pirimiphosmethyl 5/30 ℃ 15〜18 Diazinon 40/20 ℃ Liquid Etrimfos 40/24 ℃ −3.35 pyridaphenthion “SS” 54.5〜56 quinalphos 17.8 / 24 ℃ 31〜32 isoxathion 1.9 / 25 ℃ Liquid DMTP, methidathion 240/25 ℃ 39〜40 salicion (Dioxabenzofos) 58/30 ℃ 55〜56

(Organic Chlorine) Benzoepine (endosulfan) “IS” 84-88

-Fungicide- (N-heterocyclic ergosterol inhibitor) triflumizole 12.5 / pH 5.9 63.5 triforine 27-29 / R.T. 155

(Carboxamide) mepronil 12.7 / 20 ° C. 92 to 93 flutolanil 9.6 / 20 ° C. 108 pencency (pencycuron) 0.5 132 to 133 oxycarboxin 1000/25 ° C. 127.5 to 130

(Dicarboximide type) iprodione 13 136 vinclozolin <1000 108 procymidone 4.5 166 to 167

(Benzimidazole type) benomyl “IS” (Polyhaloalkylthio type) Captan 3.3 / R.T. 178

(Others) dichromezine 0.74 / 25 ° C. 250.5-253 tricyclazole 0.7 183-189 pyroquilon 4000 112> isoprothiolane 48/20 ° C. 54.5-55 probenazole (SS) 150) ”138-139 anilazine“ IS ”159-160 oxolinic acid 3.2 / 25 ° C 250> dimethirimol 1200/25 ° C 102 ferimzone 0.162g / 30 ° C 175-176

(Antibiotic agent) Kasugamycin 1.25% / 25 ° C 202-204

(Organophosphorus) EDDP, edifenphos 5 liquid IBP, iprobenfos 1000/18 ° C. liquid 22.5 to 23.8

(Organic chlorine-based) Fthalide 2.49 209 to 210 TPN, chlorothalonil 0.6 / 25 ° C. 250 to 251

(Sulfur-based) zineb 10 / RT maneb “SS” Among the above active ingredients, the present invention is preferably applied to a pyraclofos-containing suspension agent.

Of the above active ingredients, those which are oily at room temperature can be used as they are, or can be used by dissolving them in a non-volatile organic solvent which is incompatible with water. Also,
Those which are solid at room temperature can be dissolved in a non-volatile organic solvent which is incompatible with water and made into an oily state for use.

Of course, in the present invention, each of the above active ingredients can be used alone, or two or more kinds can be used in combination. When the oily substance at room temperature and the solid substance at room temperature are used together, the latter solid component at normal temperature can be dissolved in the former oily component, and both can be used as described above. It can also be used by dissolving it in an organic solvent. These aspects are appropriately determined depending on the type of active ingredient used.

The organic solvent used here is preferably an aromatic hydrocarbon. Specifically, alkylbenzenes can be mentioned, and these can be used as one kind or a mixture of two or more kinds. As the mixture (mixed solvent), a partially rectified one (a mixture of several kinds of alkylbenzene) may be used, and two or more kinds of alkylbenzenes having different carbon numbers are separately prepared and mixed and prepared. Can also be used. Such alkylbenzenes and mixtures thereof are commercially available and it is preferable to use them from an economical point of view.

The alkylbenzene has 1 to 1 in the benzene ring.
It is a compound in which several alkyl groups are substituted. Preferably, mono (substituted) in which 1 to 4 alkyl groups are substituted
These are alkylbenzene, di (substituted) alkylbenzene, tri (substituted) alkylbenzene, and tetra (substituted) alkylbenzene. Of these, mono (substituted) alkylbenzene and tri (substituted) alkylbenzene are more preferable.

The carbon number (total carbon number) of these alkylbenzenes is not particularly limited, but when an odorless preparation is desired, a solvent mainly containing alkylbenzene having a total carbon number of 20 to 26 is used. Preferably. In particular,
It is more preferable to use a mono (substituted) alkylbenzene having a total carbon number of 20 to 26. It is also possible to use tri (substituted) alkylbenzene substituted with three lower alkyl groups. The lower alkyl group is preferably a straight chain or branched chain having 1 to 4 carbon atoms. Of these, those having a methyl group are more preferable.

Specific examples of the mono (substituted) alkylbenzene include n-propylbenzene and n-butylbenzene. In addition, specific examples of the di (substituted) alkylbenzene include o-ethyltoluene and the like.

Specific examples of tri (substituted) alkylbenzene include 1,2,4-trimethylbenzene, 1,3,5-trimethylbenzene, 1,2,3-trimethylbenzene, m, p-ethyltoluene, 1, Examples thereof include 3-dimethyl-5-ethyl-benzene and 1,4-dimethyl-2-ethylbenzene. Specific examples of the tetra (substituted) alkylbenzene include 1,2,3,5-tetramethylbenzene, 1,2,4,5-tetramethylbenzene, 1,
2,3,4-tetramethylbenzene and the like can be mentioned.

The commercially available product of such a mixture of alkylbenzenes is as follows: Hysol # 100 (TM; manufactured by Nippon Petrochemical Co., Ltd .; a mixture mainly composed of C ₃ -C ₅ alkylbenzenes; this carbon number is of a substituted alkyl group). . shows the total number of carbon atoms hereinafter the same), Hisol # 150 (TM; manufactured by the company; C ₃ -C ₄ alkylbenzene mixtures principal), and the like. Also,
Pentadecyl benzene, alkene 20T (TM; Nippon Oil detergents manufactured; C ₁₄ -C ₁₆ alkyl benzene mixtures entity), alkene 100P (TM; manufactured by the company; C ₁₅ -C ₂₀ alkylbenzene mixtures mainly) and the like is also conveniently Used.
Further, as a mixture of tri (substituted) alkylbenzene isomers, a mixture of three kinds of 1,2,4-trimethylbenzene, 1,3,5-trimethylbenzene and 1,2,3-trimethylbenzene may be used.

The amount of the organic solvent used is such that the active ingredient is dissolved at a rate of 5 to 80% by weight, preferably 10 to 70% by weight. The content of the active ingredient in the suspension of the present invention is 0.1 to 75% by weight, preferably 3 to
It is 50% by weight, more preferably 5 to 35% by weight.

One of the features of the present invention is that a specific clay mineral which is a solid substance is used as a suspension aid. For this particular clay mineral, the crystalline morphology
It is a clay mineral with a swelling lattice of 2: 1 structure type. Specifically, it is a montmorillonite-saponite group (montmorilloni
te-saponite group) clay minerals or vermiculite group clay minerals.

Specific examples of the montmorillonite-saponite group clay mineral include montmorillonite.
e), beidellite, nontronite (n
ontronite), saponite, hectorite, sauconite and the like, and any of them can be used, but montmorillonite is preferable. Moreover, as a specific example of the vermiculite group clay mineral, vermiculit (vermiculit
e) are mentioned.

The montmorillonite preferably used in the present invention refers to sodium montmorillonite, which is one of natural colloidal hydrous aluminum silicates and is known as the main component of bentonite. This is a highly hydrophilic substance, and when added to water,
Since it is a colloidal dispersion that absorbs water between the crystal layers and exhibits thixotropy, it is a suitable suspension aid in the present invention, and as a commercially available product, Kunipia F (TM; manufactured by Kunimine Industries Co., Ltd.) may be mentioned. You can

It is also a feature of the present invention that the particle size distribution of the 2: 1 structural type clay mineral is 0.5 to 50 μm. If it is less than 0.5 μm, it is difficult to obtain a desired suspending agent, while if it exceeds 50 μm, the clay mineral begins to precipitate and is difficult to disperse uniformly, which is not preferable. In particular, 0.5 to 20 μm is preferable, and 0.5 is more preferable.
~ 15 μm. As the average particle size of the clay mineral, it is preferable to use finely pulverized particles of about 1 to 5 μm in order to improve the dispersion effect of the suspended oily particles, and 1 to 3 μm.
Is more preferable.

Further, in the present invention, in order to obtain good suspension stability, the above clay mineral is added in an amount of 0.1 to 10
It is preferable to add 3.0 parts by weight, and it is more preferable to set the mixing ratio in the range of 0.1 to 1.5 parts by weight in order to obtain a low-viscosity suspending agent.

As described above, the present invention has a particle size distribution of 0.
It is characterized by blending 5 to 50 μm of 2: 1 structure type clay mineral fine powder, and further characterized by using nonionic surfactant of HLB4 to 7 and nonionic surfactant of HLB8 to 20 in combination. It is what Preferably, the hydrophobic surfactant has an HLB of 4 to 6, and the hydrophilic surfactant has an HLB of
It is in the range of 10 to 20. And by this combination combination,
A suspension having excellent suspension stability can be obtained, and moreover,
It can be a low-viscosity suspending agent of the present invention, which is 20 to 300 cps (viscosity value at 20 ° C. measured by a Brookfield viscometer).

The amount of the nonionic surfactant added is
5 as total amount of mixed nonionic active agent based on total suspension
The amount is preferably -25 parts by weight, more preferably 10-20 parts by weight. By adding within this range, an oil-in-water suspension having a low viscosity within the above range, good dispersibility in water even at the time of dilution, and good formulation stability over a long period of time is prepared. can do.

Nonionic surfactants of HLB 4 to 7 and HL
The mixing ratio of the nonionic surfactant of B8 to 20 is H
LB8 to 20 / HLB4 to 7 = 0.05 to 10/1 (weight ratio), preferably 0.05 to 5/1, and more preferably 0.1 to 3/1.

In the present invention, 0.1 to 0.5 part by weight of an anionic surfactant can be added if necessary.
By this addition, the emulsified particles can be made smaller, the sedimentation speed of the suspended oily particles can be suppressed, and a stable oil-in-water type suspending agent can be obtained.

As the nonionic surfactant, any nonionic surfactant can be used as long as it has the above-mentioned hydrophilic / lipophilic balance (HLB) capable of preparing an oil-in-water emulsion. Also, an anionic surfactant added as necessary can be optionally used.

Examples of these nonionic surfactants include, but are not limited to, the following. (HLB4-7 nonionic surfactant) -Sorbitan monooleate (HLB 4.3) -Propylene glycol monolaurate (HLB 4.5) -Sorbitan monostearate (HLB 4.7) -Diethylene glycol monostearate (HLB 4.7) ・ Glycerol monostearate (self-emulsifying) (HLB 5.5) ・ Diethylene glycol monolaurate (HLB 6.1) ・ Sorbitan monopalmitate (HLB 6.7)

(HLB 8-20 nonionic surfactant) -Sorbitan monolaurate (HLB 8.6) -Polyoxyethylene (4) lauryl ether (HLB 9.5) -〃 (4) Sorbitan monostearate (HLB 9.6) ) ・ 〃 (5) 〃 Monooleate (HLB10.0) ・ 〃 (4) 〃 Tristearate (HLB10.5) ・ 〃 (4) 〃 Trioleic acid ester (HLB11.0) ・ Polyoxyethylene Glycol 400 monooleate (HLB11.4) ・ 〃〃〃 Monostearate (HLB11.6) ・ Polyethylene glycol 400 monolaurate (HLB13.1) ・ Polyoxyethylene (4) sorbitan monolaurate Ester (HLB13.3) ・ 〃 (20) 〃 Monostearate (HLB14.9) ・ 〃 (20) 〃 Monooleate (HLB15.0) ・ 〃 (20) Stearyl ether HLB15.3) ・ 〃 (20) oleyl ether (HLB15.4) ・ 〃 (20) Sorbitan monopalmitate (HLB15.6) ・ 〃 (20) Cetyl ether (HLB15.7) ・ 〃 (30) Stearic acid ester (HLB16.0) ・ 〃 (40) 〃 (HLB16.9) ・ 〃 (100) Stearic acid ester (HLB18.8)

Further examples of commercially available nonionic surfactants of this type include the following, and any of them can be used in the present invention.・ Sorbitan alkylate (eg Newcalgen D935;
TM; Takemoto Yushi Co., HLB 4.3) ・ Polyoxyethylene nonyl phenyl ether (eg, Nonipol 85; TM; Daiichi Kogyo Seiyaku Co., HLB 10) ・ Polyoxyethylene alkylaryl ether (eg,
Neugen EIA-142 (EA-142); TM; Daiichi Kogyo Seiyaku Co., Ltd., HLB 14) Sucrose fatty acid ester (eg, DK ester F-160; TM;
Daiichi Kogyo Seiyaku Co., Ltd., HLB15-16) ・ Polyoxyethylene sorbitan monolaurate (eg,
Newcalgen D941; TM; Takemoto Yushi Co., Ltd., HLB 16.7) ・ Special polymer nonionic activator (eg, Newcalgen D302)
0; TM; HLB 19.0 manufactured by Takemoto Yushi Co., Ltd.)

In the present invention, as described above, an anionic surfactant can be blended, if necessary.
Examples of this type of anionic surfactant include the following commercial products.・ Dialkylsulfosuccinate sodium salt (eg, Newcalgen EP-70G; TM; manufactured by Takemoto Yushi Co., Ltd.) ・ Polyoxyethylene phenylphenol sulfate (eg,
Agrisol FL2017; TM; Kao Soap) ・ Sodium alkylnaphthalene sulfonate (eg, Newcargen BX-C; TM; Takemoto Yushi Co., Ltd.) ・ Sodium β-naphthalene sulfonate formalin condensate (eg, Labelin FM-L; TM; manufactured by Daiichi Kogyo Seiyaku Co., Ltd.)

In addition to the above components, the suspension of the present invention may of course be mixed with other general auxiliary agents such as antifreezing agents and antifoaming agents. For example, ethylene glycol (manufactured by Mitsubishi Yuka Co., Ltd.) as an antifreezing agent and Antihome E-20 (TM; manufactured by Kao Atlas Co.) as an antifoaming agent can be added.

The suspending agent of the present invention can be produced by a well-known / conventional means, but preferably, an oily agricultural and horticultural active ingredient and a hydrophobic nonionic surfactant (HLB4 to 7).
Nonionic surfactant) to form an oil phase mixture, and this mixture is then mixed with a hydrophilic active agent (HLB8-20).
Nonionic surfactant) and a suspension aid (2: 1 fine-structured clay mineral fine powder) are mixed in an aqueous phase and stirred to form an oil-in-water suspension.

The obtained suspension is homogenized by various methods. As an example, after forming an emulsified system with a homomixer, a fine milling process is performed using a ball mill such as DYNO-MILL or a microfluidizer. This results in a sufficiently small particle size (average particle size 0.4 ~
It is possible to disperse oil droplets having a particle size of 1.5 μm) and to control the particle size freely.

The suspension of the present invention can be used by further diluting it with water at the time of use so as to obtain an effective pesticide concentration. Further, as an important use method of the present invention, which has a low viscosity and excellent dispersibility in water, there is direct spraying of the undiluted solution. For example, it is also used to efficiently pest control a river in which a pest or a disease-causing epidemic is generated by directly injecting the undiluted solution into the river by a helicopter from the sky and quickly spreading it on the river surface.

The present invention, as described above in detail, has a specific
By using a 2: 1 structural type clay mineral fine powder and a nonionic surfactant having different HLB in combination, an oil-in-water type suspension containing an oily active ingredient for agriculture and horticulture has a low viscosity. In addition, it is possible to obtain the above-mentioned suspension having good dispersibility in water even when diluted, and having good formulation stability for a long period of time.

More specifically, the present invention has a particle size distribution of 0.5.
-50 μm 2: 1 structural type clay mineral fine powder with an average particle size of 1-5 μm and its blending amount (0.1-
3.0 parts by weight) and the combined use of the above surfactants and the addition amount (5 to 25 parts by weight) of them are organically combined so that not only good dispersibility in water but also 20 to 300 cps (2
An oil-in-water suspension having a low viscosity of (viscosity value measured by B-type viscometer at 0 ° C.) is obtained. And since it has such a low viscosity, it is extremely easy to discharge it from the container, and even if it is directly put into a river by, for example, a helicopter, it settles in water and the oil droplets aggregate and coalesce. Without doing so, it can spread quickly on the surface of the river and control pests efficiently over a wide area.

Further, the suspending agent of the present invention can be used in combination with other water-soluble active ingredients dissolved in water as a dispersion medium, which is also included in the present invention. Examples of such active ingredients are given below. In addition, "g" in the term of solubility indicates the number of grams in 1 liter of the solvent, and
“S” indicates “dissolved”, “VS” indicates “easy-dissolved”, and “RT” indicates “room temperature (15 to 25 ° C.)”.

-Insecticide- (Carbamate type) Solubility Melting point (° C) Methomyl (methomyl) 58g / 20 ° C 78-79 (others) thiocyclam 84g / 20 ° C 125-128 Cartap 200g / 20 ℃ 179-181 Nitenpyram 300g / 20 ℃ 85

(Organophosphorus) acephate 650 g / 20 ° C. 91 to 92 ESP, oxdeprofos “S” liquid dimethoate 25000 g / 21 ° C. 51 to 52 vamidothion 4000g / 20 ℃ 46-48 DEP, trichlorfon 154g / 25 ℃ 83-84 DDVP, cyclochlorvos 10000 / RT liquid

-Fungicide- (Antibiotic agent) Validamycin A "VS" 135 mildiomycin> 1 g> 250 The water-soluble active ingredients that can be used in combination as described above are effective for each ingredient. The blending amount can be appropriately determined based on the amount.

[0064]

EXAMPLES Next, examples of the present invention will be given together with comparative examples.
The present invention will be described in more detail. Example 1 The following emulsion was prepared. (Parts by weight) Pyraclofos 35 parts Sorbitan alkylate (NK D935; TM; HLB4.3) 13.5 parts Special polymeric nonionic activator (NK D3020; TM; HLB19.0) 1.5 parts Montmorillonite (Kunipia F; TM; Particle size distribution 0.5-10 μm; Average particle size: 2 μm) 0.4 parts Antifreeze 5 parts Defoamer 0.2 parts Water 100 parts

First, pyraclofos and a special polymer nonionic activator (Newkalgen D935) were thoroughly mixed in a container to obtain a homogeneous oily mixture. Similarly, put water in another container, dissolve or disperse sorbitan alkylate (New Cargen D3020) and montmorillonite (Kunipia F), antifreeze agent and defoaming agent in it, and mix well to obtain a homogeneous aqueous solution. A mixture was obtained, which was warmed to 70 ° C. immediately before emulsification.

Next, the oily mixture was put into the aqueous mixture heated to 70 ° C. with stirring with a homomixer, and after the addition was completed, the mixture was emulsified at 7,000 rpm for 5 minutes. The obtained suspension was evaluated for formulation viscosity, dispersibility in water and formulation stability according to the test examples described below, and the results are shown in Table 1.
It was shown to.

Example 2 The following emulsion was prepared. (Parts by weight) Pyraclofos 5 parts Sorbitan alkylate (NK D935; TM; HLB4.3) 13.5 parts Special polymeric nonionic activator (NK D3020; TM; HLB19.0) 1.5 parts Montmorillonite (Kunipia F; TM; particle size distribution 0.5 to 10 μm; average particle size: 2 μm) 1.0 part Antifreeze agent 5 parts Defoamer 0.2 part Water 100 parts This was obtained in the same manner as in Example 1 above to obtain a suspension agent. .. The obtained suspension was evaluated for formulation viscosity, dispersibility in water and formulation stability in the same manner as in Example 1 above, and the results are shown in Table 1.

Comparative Examples 1 and 2 Emulsions of Comparative Examples 1 and 2 were prepared in the same manner as in Examples 1 and 2 except that montmorillonite was used. The obtained suspension was evaluated for formulation viscosity, dispersibility in water and formulation stability in the same manner as in Example 1, and the results are shown in Table 1.

Comparative Example 3 The following emulsion was prepared. (Parts by weight) Pyraclofos 35 parts Sorbitan alkylate (NK D935; TM; HLB4.3) 22.5 parts Special polymeric nonionic activator (NK D3020; TM; HLB19.0) 2.5 parts Antifreeze agent 5 parts Defoaming agent 0.2 part Water 100 parts Total This was obtained in the same manner as in Example 1 above to obtain a suspension. The obtained suspension was evaluated for formulation viscosity, dispersibility in water and formulation stability in the same manner as in Example 1, and the results are shown in Table 1.

(Test Example-Formulation Viscosity) The viscosity was measured with a B type viscometer using a No. 2 rotor at 20 ° C. (Test Example-Dispersibility in Water) Dispersibility in water is as follows: About 250 μl of the droplet of the preparation is gently dropped from above into a 250 ml measuring cylinder containing 3 times hard water, and the droplet is completely dispersed by the time it reaches the bottom. Cases were indicated by ○, those in which the droplets were dispersed but were not completely dispersed before reaching the bottom, were indicated by Δ, and those in which the droplets were not dispersed but reached the bottom as they were were ×.

(Test example-formulation stability) The stability of the preparation is
Immediately after preparation of the preparation, the solution was placed in a test tube so that the liquid height was 10 cm, and allowed to stand at room temperature for 1 month, and the degree of aqueous phase separation at that time was expressed in%.

[0072]

[Table 1]

As is clear from Table 1, in the formulations containing montmorillonite (Examples 1 and 2), the degree of phase separation was very small despite the low viscosity, and the dispersibility in water was good. I can understand that. This formulation was excellent in redispersibility because the aggregation phenomenon was suppressed, and was easy to handle because it returned to a uniform state by gentle stirring.

On the other hand, in the formulations containing no montmorillonite (Comparative Examples 1 and 2), the viscosity was low and the dispersibility in water was good, but they were largely separated into two phases over time. At this time, since the droplets aggregated and coalescence proceeded, the separated two phases were irreversible even when stirred and were not uniform and were not suitable for use. Further, a formulation in which the amount of the active agent is increased (Comparative Example 3)
Then, the viscosity became higher. Therefore, although phase separation hardly occurs, dispersibility in water is poor and handling is difficult. A similar phenomenon was observed when a thickener was used.

(Comparative Example 4) In the above-mentioned Example 1, only the special polymer nonionic activator (NK D3020; TM; HLB19.0) was used instead of the sorbitan alkylate (NK D935; TM; HLB4.3) in 15%. An emulsion was prepared in the same manner by mixing parts.

(Comparative Example 5) In Example 1, the sorbitan alkylate (NK D935; TM; HLB4.3) alone was used instead of the special polymer nonionic activator (NK D3020; TM; HLB19.0). An emulsion was prepared in the same manner by mixing parts.

(Test Example) The emulsions of Comparative Examples 4 and 5 prepared by blending only one type of nonionic surfactants without using two types of nonionic surfactants different in HLB emulsified the oily active ingredient (pyraclofos). Was insufficient, the formulation stability was remarkably lacking, and the oil phase and the aqueous phase were separated immediately after the preparation, making formulation difficult.

[0078]

As described in detail above, the present invention has a specific
An oil-in-water suspension containing an oily active ingredient for agricultural and horticultural use was prepared by using 2: 1 structural type clay mineral fine powder and also using a nonionic surfactant having a different HLB.
~ 300 cps (viscosity value measured at 20 ° C with a B-type viscometer) having a low viscosity, good dispersibility in water even when diluted, and good formulation stability over a long period of time. The effect that can be obtained occurs.

Claims (3)

[Claims] 1. (a) Oily active ingredient for agricultural and horticultural use, (b) 2: 1 structural type clay mineral fine powder having a particle size distribution of 0.5 to 50 μm, (c) H
A suspending agent comprising a nonionic surfactant of LB4 to 7; (d) a nonionic surfactant of HLB8 to 20; and (e) water. 2. The suspending agent according to claim 1, wherein the 2: 1 structural type clay mineral is a montmorillonite-saponite group clay mineral. 3. The viscosity measured by a B-type viscometer is 20 at 20 ° C.
The suspending agent according to claim 1, which has a viscosity of 300 cps.