JP6213973B2 - Composition - Google Patents

Description

  The present invention relates to a composition capable of obtaining preparations with a wide range of sensory characteristics because cholesteric liquid crystals are beautifully colored with a small amount.

Cholesteric liquid crystals have strong moisture retention and are excellent in appearance, and some products are on the market.
If all of the products are liquid crystals, there are many sensory problems, and liquid crystals are blended in capsules (Patent Document 2) and linear patterns (Patent Document 3) in an aqueous gel to try to solve the defects of liquid crystals. It has been.
However, even in the above-described method, if the liquid crystal part has a certain thickness, there is no color development as a liquid crystal, and it is necessary to add a certain amount or more of liquid crystal.

Japanese Patent Laid-Open No. 01-246209 Japanese Patent Laid-Open No. 03-240715 Japanese Patent Laid-Open No. 01-211512

  An object of the present invention is to reduce the blending amount of liquid crystals while allowing a wide range of feelings to be used and maintaining color development as liquid crystals.

As a result of intensive studies by the present inventors, when water-insoluble particles having a lipophilic surface are blended with a cholesteric liquid crystal component, the cholesteric liquid crystal is adsorbed on the water-insoluble particles and sufficient color development can be obtained even with a small amount of cholesteric liquid crystal. I understood it.
This will be described in detail below.

The component constituting the cholesteric liquid crystal is not particularly limited, and fatty acid esters such as cholesterol, cholestanol, and phytosterol can be used. For example, cholesterol acetate ester, cholesterol propionate ester, cholesterol butyrate ester, cholesterol hexanoate ester, cholesterol octanoate ester, cholesterol nonanoate ester, cholesterol lauryl ester, cholesterol decanoate ester, cholesterol myristic acid ester, cholesterol palmitic acid Ester, cholesterol stearate ester, cholesterol isostearate ester, cholesterol oleate ester, cholestanol acetate ester, cholestanol propionate ester, cholestanol butyrate ester, cholestanol hexanoate ester, cholestanol octanoate ester, cholestanol nonanoate ester Cholestanol lauryl Esters, cholestanol decanoate, cholestanol myristic ester, cholestanol palmitate, cholestanol stearate, cholestanol isostearate, cholestanol oleate, phytosterol acetate, phytosterol propionate, phytosterol butyrate Phytosterol hexanoate, phytosterol octanoate, phytosterol nonanoate, phytosterol laurate, phytosterol decanoate, phytosterol myristic ester, phytosterol palmitate, phytosterol stearate, phytosterol isostearate, phytosterol Ruorein acid ester or the like can be used. Also used are cholesterol halides such as cholesterol chloride and cholesterol bromide, cholestanol halides such as cholestanol chloride and cholestanol bromide, plant sterol halides such as batosterol chloride, sitosterol bromide, campesterol chloride, campesterol bromide, etc. can do.
From the above, the type and amount of the raw material are selected in consideration of the desired color development and viscosity.

The water-insoluble particles having a lipophilic surface are preferably transparent or have a low degree of coloring. If the coloring is strong, a large amount of liquid crystal may be required, or the color development of the liquid crystal may be inhibited in some cases. In addition, the substance to be used is a substance that exhibits a solid or gel shape as a whole.
As will be described later, the surface of the particles needs to be lipophilic to such an extent that the cholesteric liquid crystal is adsorbed to the surface of the particles so as to be stable over time when mixed with an aqueous liquid.
For this reason, depending on the type of resin, particles in which the resin surface is coated with silicone containing organic modification are used.
For example, it is composed of one or more of dimethicone, (vinyl dimethicone / methicone silsesquioxane) cross polymer, (diphenyl dimethicone / vinyl diphenyl dimethicone / silsesquioxane) cross polymer, (dimethicone / vinyl dimethicone) cross polymer, etc. Resin particles with a lipophilic surface.
Alternatively, particles such as silica, (HDI / trimethylol hexyl lactone)) cross polymer, etc., which are coated with silicone or the like containing organic modification can be exemplified.
Some of the particles satisfying the above conditions are commercially available. KMP-590, KSP-100, KSP-101, KSP-102, KSP-105, KSP-300, Toray Dow, manufactured by Shin-Etsu Chemical Co., Ltd. Corning Silicone, Trefil E-506S, Trefil E-508, Trefil E-702, Toago Pigment, PLASTIC POWDER D-400HP, etc. can be used.
The particle diameter is preferably 2 μm or more, and if it is 2 μm or less, the degree of color development of the liquid crystal is low and there is no merit as a liquid crystal.
The amount of cholesteric liquid crystal is 0.5 to 10 times the amount of particles, although it varies greatly depending on the type and size of particles and the type of cholesteric liquid crystal.
Moreover, although the compounding quantity of a cholesteric liquid crystal changes with various conditions, 0.5 to 20 weight% of a composition is preferable. If it is 0.5% by weight or less, the degree of color development is low, and if it is 20% by weight or more, a sensory problem occurs.
It should be noted that the blending of the oil phase other than the cholesteric liquid crystal must be limited to an amount that does not impair the color of the liquid crystal.

The oil phase component is blended by selecting necessary raw materials from the raw materials exemplified below.
Mineral oils such as petrolatum, paraffin, ceresin, microcrystalline wax, olefin oligomer, liquid paraffin, liquid isoparaffin, pristane, hydrogenated polybutene, hydrogenated polydecene, heavy liquid isoparaffin.
Fatty acids such as lauric acid, myristic acid, palmitic acid, stearic acid, behenic acid, oleic acid, linoleic acid, linolenic acid, docosahexaenoic acid, eicosapentaenoic acid, and 12-hydroxystearic acid.
Isopropyl myristate, isopropyl palmitate, butyl stearate, hexyl laurate, myristyl myristate, oleyl oleate, decyl oleate, octyldodecyl myristate, hexyl decyl dimethyloctanoate, cetyl lactate, myristyl lactate, lanolin acetate, monostearate Esters such as ethylene glycol acid, propylene glycol monostearate, propylene glycol dioleate;
Examples include cetyl alcohol, stearyl alcohol, oleyl alcohol, lanolin alcohol, cholesterol, phytosterol and other alcohols. Furthermore, oil-soluble vitamins such as vitamin A oil, vitamin A palmitate, vitamin A acetate, riboflavin, vitamin C dipalmitate, ergocalciferol, vitamin E, vitamin E acetate, vitamin E nicotinate.
Ethyl hexyl paramethoxycinnamate, isopropyl paramethoxycinnamate, octyl paramethoxycinnamate, octyl dimethoxybenzylidenedioxoimidazolidinepropionate, hexyl diethylaminohydroxybenzoylbenzoate, t-butylmethoxydibenzoylmethane, ethylhexyltriazone, UV absorbers such as octoclerin, oxybenzone, hydroxybenzophenone sulfonic acid, sodium dihydroxybenzophenone sulfonate, dihydroxybenzophenone, paraaminobenzoic acid.
Oil-soluble components of plants such as eucalyptus oil, wild rose oil, armor oil, roman chamomile oil, fennel oil, mint oil, bergamot oil, peppermint oil, spearmint oil, basil oil, thyme oil, laurel leaf oil, oil-soluble licorice and the like.
Examples include beta-carotene, astaxanthin, cholesterol, phytosterol, ceramide, guaiazulene, benzyl nicotinate, dibutylhydroxytoluene and butylhydroxyanisole.

Next, although it is an aqueous phase, some of the raw materials illustrated below besides water are selected, and a required prescription is created.
Polyhydric alcohol is ethylene oxide, ethylene glycol, diethylene glycol, triethylene glycol, ethylene glycol monoethyl ether, ethylene glycol monobutyl ether, diethylene glycol monomethyl ether, diethylene glycol monoethyl ether, polyethylene glycol, propylene oxide, propylene glycol, polypropylene glycol, 1 , 3-butylene glycol, pentyl glycol, glycerin, diglycerin, polyglycerin, erythritol, pentaerythritol, threitol, arabitol, xylitol, ribitol, galactitol, sorbitol, mannitol, lactitol, maltitol and the like.
Water-soluble polymers such as carboxyvinyl polymer, alkyl-modified carboxyvinyl polymer, quince seed gum, and hydroxymethylcellulose.
In addition, necessary raw materials such as polysaccharides, chelating agents, preservatives, pigments and water-soluble drugs are blended.

These are prepared according to a standard method, but it is natural that the liquid crystal is in a state where the surface is adsorbed on lipophilic water-insoluble particles.
Usually, the liquid crystal is heated and dissolved, and the surface may be brought into contact with lipophilic water-insoluble particles.
In addition, the number of an Example shows a weight part.

Example-1
A)
Phytosteryl oleate 0.5
Cholesteryl decanoate 0.5
Cholesteryl nonanoate 0.5
Cholesteryl 12-hydroxystearate 0.5
Water-insoluble particles with lipophilic surface Note 1) 1.0
B)
Purified water 80.0
Glycerin 5.0
Xanthan gum 0.2
Carboxyvinyl polymer 0.3
L-Arginine 0.5
Trimethylglycine 2.0
1,2 pentanediol 5.0
1,3 propanediol 4.0
Note that the water-insoluble particles having a lipophilic surface of Note 2 were manufactured by Toyo Pigment Co., Ltd. and trade name PLASTIC POWDER D-400HP.
In the production method, each of A) and B) was heated and stirred until other than “water-insoluble particles having a lipophilic surface” were dissolved, and A) was added to B) and cooled.

Example-2
A)
Dihydroxycholesteryl oleate 2.0
Cholesteryl nonanoate 2.0
Cholesteryl butyrate 1.0
Dihydrocholesteryl butyrate 0.3
Phytosteryl oleate 0.2
Stearyl glycyrrhetinate 0.2
Vitamin E 0.3
Water-insoluble particles with lipophilic surface Note 2) 2.0
B)
Purified water 79.8
Sodium carboxymethylcellulose 5.0
Sodium hyaluronate 2.0
1,3 Butylene glycol 5.0
Methyl paraoxybenzoate 0.2
Note that the water-insoluble particles having a lipophilic surface of Note 2 were manufactured by Shin-Etsu Chemical Co., Ltd. and trade name KSP-102.
The production method was the same as that in Example-1.

  In any of the examples, it was found that even if the amount of liquid crystal was smaller than before, the color was beautifully developed, the feeling of use was not sticky, and a good preparation was obtained.

Claims (1)

A composition comprising a particle in which a cholesteric liquid crystal component is adsorbed on a lipophilic water-insoluble resin and an aqueous phase. (However, cosmetics with pigments and cosmetics in which particles with cholesteric liquid crystal components adsorbed on a water-insoluble resin with a lipophilic surface on a clear, highly viscous gel are excluded)