JP5574581B2 - Solidifying skin adhesive composition suitable for skin replica agent - Google Patents

Description

  The present invention relates to a solidifying skin adhesive composition, and more particularly to a solidifying skin adhesive composition suitable for making a skin replica to which a three-dimensional shape of the skin is to be transferred.

In the field of cosmetics, solidifying skin pressure-sensitive adhesive compositions are widely applied to pack cosmetics and the like by making use of adhesiveness and fixing properties such as square plugs. In recent years, application as a replica material has been added to such an application range. This is because there is a growing need for cosmetics to deal with the skin quality of individuals, and it has been demonstrated that skin replicas are useful for distinguishing between individual skin types.
That is, the replica is a means for non-invasive measurement of skin function by transferring the shape by deforming and hardening the polymer according to the shape of the skin, and using this, various skin state discrimination methods, Various methods for selecting cosmetics have been devised (see, for example, Patent Document 1, Patent Document 2, and Patent Document 3). The basic technology of this “replica” has existed for a long time, but it is a technical problem to accurately transfer three-dimensional shapes such as skin relief without burden on the skin, with good reproducibility. some with a solvent melting, the method utilizing rehardening was seen major leaps by turned to a method of curing the coating film forming composition having a viscous. This is because the development of such a method has made the procedure extremely easy and makes it easy for amateurs to make replicas. At present, it is also used as a counseling tool at cosmetics sales sites. On the other hand, there is an example where the replica is peeled off in a state where the solidification is insufficient, and the undulations of the skin cannot be read, and the replica is taken again. The more important issue with such a replica agent is solidification and hardening. The trend has been to shorten the time (drying time) and to clearly transfer the three-dimensional shape of the skin. Such shortening of the solidification / curing time leads to more efficient counseling. For the purpose of shortening the solidification / curing as described above, a technique for clearly transferring the solid three-dimensional shape of the skin by containing the powder by shortening the solidification / curing time by using polyvinyl alcohol as a film forming agent (for example, Patent Document 4), which contains polyvinyl alcohol which may be partially acetylated, polyvinylpyrrolidone and polyvinyl acetate, further shortens the solidification / curing time, and by incorporating powder, the three-dimensional shape of the skin Although a faithful transfer technique (see, for example, Patent Document 5) is also disclosed, in order to smoothly proceed with counseling etc. at the sales site without failure, further shortening of the solidification / curing time and the three-dimensional shape of the skin A clear transfer was desired.

On the other hand, a method in which a first agent containing an epoxy resin and a second agent containing an organic amine are mixed and reacted at the time of use (for example, see Patent Document 6), an ethyl acrylate / ethyl methacrylate copolymer as a coating component Curing time is shortened, such as a method used (for example, see Patent Document 7), a method using a curable silicone (for example, Patent Document 8), and a method using a salt of alginic acid (for example, see Patent Document 9). Although the technology is also disclosed, in such a method, there are many defects in the obtained replica specimen due to another factor that is not caused by insufficient solidification / curing. There was a case. This can be caused by the fact that the product is cured before it is transferred due to its premature curing, the adhesiveness with the skin is high, a part of the material remains on the skin, and a sudden contraction during curing. Occurs, the faithful transfer of the skin shape cannot be achieved, there are problems in the form maintainability as a coating, and the transferred form cannot be maintained and is broken. That is, the improvement of moderate peelability and shape maintenance after solidification / curing is also a major issue.

It was said that the solid shape of the skin was clearly transferred as the reason for including the powder (see, for example, Patent Document 4 and Patent Document 5), but silica, nylon powder, calcium silicate, calcium carbonate, and hollow structure were used. By containing spherical powder such as acrylic resin powder that may have and silicone polymer in the form of silicone emulsion in the coating composition, the solidification and curing time can be shortened surprisingly, and the three-dimensional shape of the skin A technique for producing an excellent skin replica that was clearly transferred and had no residue on the skin was obtained. No solidifying skin adhesive composition containing such a spherical powder and a silicone polymer in the form of a silicone emulsion is known at all.

JP 2002-165777 A JP 2001-170028 A JP 2000-315257 A Japanese Patent Laid-Open No. 04-022340 JP 2005-164517 A JP 2002-355235 A JP 10-314146 A JP-A-11-169453 JP 2004-173801 A

The present invention has been made under such circumstances, and an object of the present invention is to provide a solidifying skin pressure-sensitive adhesive composition having excellent usability such as a short solidification / curing time.

In view of such a situation, the present inventors sought for a solidifying skin adhesive composition with excellent usability, and as a result of intensive research efforts, water-soluble polymers, silica, nylon powder, calcium silicate, Spherical powder such as calcium carbonate, acrylic resin powder that may have a hollow structure, polyethylene powder, high-polymerization degree methylpolysiloxane, methylpolysiloxysilicic acid, methylsiloxane network polymer , and silicone polymer in silicone emulsion The solidifying skin pressure-sensitive adhesive composition contained in this form has been found to have such properties, and the present invention has been completed. That is, this invention relates to the technique shown below.
(1) Solidifying skin characterized by containing 5 to 15% by mass of a water-soluble polymer, one or more selected from the following spherical powders, and a silicone emulsion. Adhesive composition.
(Powder) Silica, nylon powder, calcium silicate, calcium carbonate, acrylic resin powder which may have a hollow structure, polyethylene powder, high polymerization degree methylpolysiloxane, methylpolysiloxysilicate, methylsiloxane network weight Coupling (2) The solidifying skin according to (1), wherein the water-soluble polymer is polyvinyl alcohol and polyvinyl pyrrolidone in which part or all of the hydroxyl groups may be acetylated. Adhesive composition.
(3) The solidifying skin adhesive composition according to (1) or (2) , wherein the spherical powder has a particle size of 1 to 20 μm.
(4) The solidifiable skin adhesive composition according to any one of (1) to (3) , wherein the silicone emulsion is an emulsion of dimethicone and / or cyclomethicone.
(5) The solidifying skin adhesive composition according to any one of (1) to (4) , wherein the content of silicone contained in the silicone emulsion is 1 to 4% by mass relative to the total amount of the composition. (6) The solidifying skin adhesive composition according to any one of (1) to (5) , wherein the three-dimensional shape of the skin is to be transferred.

ADVANTAGE OF THE INVENTION According to this invention, the solidification skin adhesive composition which is excellent in usability | operativity, such as short solidification and hardening time, can be provided.

<Water-soluble polymer which is an essential component of the solidifying skin adhesive composition of the present invention>
The solidifiable skin adhesive composition of the present invention contains a water-soluble polymer as an essential component, and the water-soluble polymer desirably has a film-forming ability. Examples of such water-soluble synthetic polymers include polyvinyl alcohol, polyacrylamide, polyvinyl methyl ether, polyisopropylacrylamide, polyethylene oxide, and cellulose derivatives (for example, methyl cellulose, ethyl cellulose, methyl hydroxypropyl cellulose, hydroxypropyl cellulose, hydroxyethyl cellulose, etc.) And starch-based (soluble starch, methyl starch, etc.), propylene glycol alginate, guar gum, locust bean gum, tragacanth, gelatin, casein, dextrin, pullulan, starch (corn starch, etc.) and the like. The preferable content of these water-soluble polymers in the solidifying skin adhesive composition of the present invention is 1 to 5% by mass, more preferably 2 to 4% by mass, based on the solidifying skin adhesive composition. %. If the total content of the water-soluble polymer is too small, there are cases where it is difficult to form a film, and if it is too large, the uniformity of the film may be impaired. Among such water-soluble polymers, a combination of polyvinyl alcohol and polyvinyl pyrrolidone, in which some or all of the hydroxyl groups may be acetylated, is particularly preferable. This is because the combination of the water-soluble polymers forms a film having excellent uniformity and shape maintenance.

Some or good port polyvinyl alcohol even though all are acetylation of the hydroxyl group can be used as cosmetic general purpose material. Among them, particularly preferred is a polyvinyl alcohol portion of the hydroxyl groups are acetylated, the polyvinyl alcohol in which the portion of the hydroxyl groups are acetylated, 5-20% of all hydroxyl groups are acetylated Those are preferred. Such polyvinyl alcohol or polyvinyl alcohol in which some of the hydroxyl groups are acetylated may contain only one species or may contain two or more species in combination. The preferable content of the water-soluble polymer in the skin replica composition such as polyvinyl alcohol or polyvinyl alcohol in which a part of the hydroxyl groups thereof is acetylated is 1 to 20% by mass based on the total amount of the composition. Yes, more preferably 3 to 15% by mass. As such a polyvinyl alcohol in which a part of the hydroxyl group is acetylated, there is a commercially available one, which can be purchased and used. An example of such a commercially available product is preferably “GOHSENOL EG-30” (registered trademark) manufactured by Nihon Gosei Co., Ltd. Moreover, as said polyvinylpyrrolidone, if it is used by cosmetics etc., it can be used without a special limitation. Use in combination with polyvinyl pyrrolidone and polyvinyl alcohol in which some or all of the hydroxyl groups described above may be acetylated may be more preferable because the solidification / curing time may be further shortened. Such polyvinyl pyrrolidone already exists on the market, and such a commercial product can be purchased and used. As a preferable commercially available product, for example, “Lubicol K-90” manufactured by BASF can be exemplified. In the solidifying skin pressure-sensitive adhesive composition of the present invention, the preferable content of such polyvinylpyrrolidone is 1 to 5% by mass, more preferably 1.5 to 4.5% by mass. In a particularly preferred form, the mass ratio of polyvinyl alcohol, which may have some or all of the hydroxyl groups acetylated, to polyvinyl pyrrolidone is preferably 1: 2 to 2: 1, more preferably 2: 3 to 3: 2.

< Spherical powder which is an essential component of the solidifying skin adhesive composition of the present invention>
Solidification of the skin adhesive composition of the present invention, a spherical powder selected from powder group shown in the following, contains a silicone polymer below the silicone emulsion form as essential components. The spherical powder Ru can be used and the general-purpose material for cosmetics. By taking the form of such spherical This, together with the releasability from the skin of the coating is improved, the form maintaining property of the coating, to shorten the hardening and curing time is promoted. The average particle size is preferably 1 to 20 μm, more preferably 2 to 15 μm. Such a spherical powder can be used by classifying general raw materials in advance, adjusted so as to be within the above particle size range, or selecting a commercially available product that falls into such a characteristic value, Can also be used. Examples of such commercially available products include “HOLLOWY-N15” (silicic anhydride, average particle size 9 to 13 μm; spherical shape) manufactured by Catalyst Kasei Kogyo Co., Ltd. The content of the spherical powder is 5 to 15% by mass, more preferably 7 to 10% by mass, based on the total amount of the composition. If the amount is too large, the feel at the time of application may be poor. If the amount is too small, the shortening of the setting / curing time may not be expected.
(Powder) Silica, Nylon powder, Calcium silicate, Calcium carbonate, Acrylic resin powder that may have a hollow structure, Polyethylene powder, High polymerization degree methylpolysiloxane (excluding solvent-soluble ones), Methylpolysiloxysilicic acid, methylsiloxane network polymer

<Silicone polymer which is an essential component of the solidifying skin adhesive composition of the present invention>
The solidifying skin adhesive composition of the present invention contains spherical powder selected from the powder group shown above and a silicone polymer in the form of a silicone emulsion described below as essential components. Examples of the silicone polymer include dimethicone having a high polymerization degree and an elastic body soluble in a solvent such as cyclomethicone (silicone elastomer), cross-linked methylpolysiloxane, acrylic-modified methylpolysiloxane, and alkyl-modified methyl. One or a combination of two or more of polysiloxane, polyether-modified methylpolysiloxane, dimethicone, phenylmethicone, cyclomethicone, amino-modified methylpolysiloxane, perfluoroalkyl-modified methylpolysiloxane, and the like can be exemplified as suitable. Dimethicone and / or cyclomethicone are preferred. The preferable content of the silicone polymer is 1 to 4% by mass, more preferably 1.5 to 3.5% by mass, based on the total amount of the composition. If the amount is too large, the form maintainability may be impaired. If the amount is too small, the additive effect may not be exhibited. Such polymers, pre Me, and emulsified with an aqueous component and an oily component, Ru is contained in the form status of the silicone emulsions. This is because the film characteristics of the solidifying skin adhesive composition of the present invention are further improved. In addition, as surfactants, fatty acid soap (sodium laurate, sodium palmitate, etc.), anionic surfactants such as potassium lauryl sulfate, alkylethanol triethanolamine ether, stearyltrimethylammonium chloride, benzalkonium chloride, Cationic surfactants such as laurylamine oxide, imidazoline amphoteric surfactants (such as 2-cocoyl-2-imidazolinium hydroxide-1-carboxyethyloxy disodium salt), betaine surfactants (alkyl betaines, Amidobetaines, sulfobetaines, etc.), amphoteric surfactants such as acylmethyltaurine, sorbitan fatty acid esters (sorbitan monostearate, sorbitan sesquioleate, etc.), glycerin fatty acids (glyceryl monostearate) ), Propylene glycol fatty acid esters (such as propylene glycol monostearate), hydrogenated castor oil derivatives, glycerin alkyl ether, POE sorbitan fatty acid esters (such as POE sorbitan monooleate, polyoxyethylene sorbitan monostearate), POE sorbite fatty acid Esters (POE-sorbitol monolaurate, etc.), POE glycerin fatty acid esters (POE-glycerin monoisostearate, etc.), POE fatty acid esters (polyethylene glycol monooleate, POE distearate, etc.), POE alkyl ethers (POE2- Octyldodecyl ether, etc.), POE alkyl phenyl ethers (POE nonyl phenyl ether, etc.), Pluronic types, POE / POP alkyl ether Nonionic surface actives such as POE / POP2-decyltetradecyl ether, Tetronics, POE castor oil / hardened castor oil derivatives (POE castor oil, POE hardened castor oil, etc.), sucrose fatty acid esters, alkyl glucosides, etc. Examples of nonionic surfactants are 1
Species or combinations of two or more can be preferably exemplified. Such silicone emulsions are commercially available, and such commercial products can be purchased and used. As a preferable commercial item, "BY22-019" by Toray Dow Corning Co., Ltd. etc. can be illustrated, for example. Moreover, you may manufacture by yourself. “BY22-019” contains 50% by mass of dimethicone and cyclopentasiloxane as a total amount.

<Production Example 1>
Below, the manufacture example of the silicone emulsion used for this invention is shown. In other words, prescription components A and B are solubilized by heating at 80 ° C., adjusted to a reduced pressure, gradually added to E with stirring, emulsified, homogenized with a homomixer, stirred and cooled, and then a silicone emulsion. 1 was obtained.

In solidification of the skin adhesive composition of the present invention, containing a silicone polymer of the silicone emulsion form according with the spherical powder. By using both in combination, synergistic effects such as shortening of solidification / curing and improvement of form maintainability are exhibited.
Of the solidifying skin adhesive composition of the present invention, the replica agent contains the water-soluble polymer, spherical powder, and silicone polymer in the form of a silicone emulsion, and there is no residue on the skin in a very short time. It is characterized in that a replica of the skin can be produced. Conventionally, as described above, solidification / curing time of a replica of an aqueous composition type that forms a film with a water-soluble polymer such as polyvinyl alcohol, excluding two-component mixed reaction type, curable silicone type and alginate type, etc. Depends on the skin temperature of the part to be applied and the thickness of the replica to be collected, but it takes about 10 to 30 minutes to solidify and cure. However, the present invention is a composition for producing a skin replica, characterized in that it contains a water-soluble polymer, a spherical powder, and a silicone polymer in the form of a silicone emulsion. Makes it possible to achieve a surprisingly short time of at least half the solidification / curing time and to obtain a highly accurate replica specimen in a very short time.

<Other components in solidifying skin adhesive composition>
The solidifying skin pressure-sensitive adhesive composition of the present invention is characterized by containing the essential component. The solidifying skin pressure-sensitive adhesive composition of the present invention can be used as a replica agent, a pack cosmetic, a transdermal absorption promoting matrix, and the like, but is particularly preferably used as a replica agent. This is because, when used as a replica agent, it exhibits excellent film form maintainability and shortening characteristics of solidification / curing, and as a result, the failure rate as a replica is significantly reduced. In the solidifying skin pressure-sensitive adhesive composition of the present invention, as an optional component other than the above, an optional component usually used in cosmetics and the like can be contained. Examples of such optional ingredients include macadamia nut oil, avocado oil, corn oil, olive oil, rapeseed oil, sesame oil, castor oil, safflower oil, cottonseed oil, jojoba oil, coconut oil, palm oil, liquid lanolin, and hardened coconut oil. Oil, wax, liquid paraffin, squalane, pristane, ozokerite, paraffin, ceresin, petrolatum, oil, wax, liquid wax, liquid paraffin, squalane, bean wax, candelilla wax, carnauba wax, ibotarou, lanolin, reduced lanolin, hard lanolin, jojoba wax , Hydrocarbons such as microcrystalline wax, higher fatty acids such as oleic acid, isostearic acid, lauric acid, myristic acid, palmitic acid, stearic acid, behenic acid, undecylenic acid, cetyl alcohol, stearyl alcohol, isostearyl Alcohol, behenyl alcohol, octyldodecanol, higher alcohol such as myristyl alcohol, cetostearyl alcohol, etc., cetyl isooctanoate, isopropyl myristate, hexyldecyl isostearate, diisopropyl adipate, di-2-ethylhexyl sebacate, cetyl lactate, malic acid Diisostearyl, di-2-ethylhexanoic acid ethylene glycol, dicaprate neopentyl glycol, di-2-heptylundecanoic acid glycerin, tri-2-ethylhexanoic acid glycerin, tri-2-ethylhexanoic acid trimethylolpropane, tri Examples include synthetic ester oils such as trimethylolpropane isostearate and pentane erythritol tetra-2-ethylhexanoate.

Also, anionic surfactants such as fatty acid soap (sodium laurate, sodium palmitate, etc.), potassium lauryl sulfate, alkylsulfuric triethanolamine ether, and cationic interfaces such as stearyltrimethylammonium chloride, benzalkonium chloride, laurylamine oxide Activators, imidazoline amphoteric surfactants (2-cocoyl-2-imidazolinium hydroxide-1-carboxyethyloxy disodium salt, etc.), betaine surfactants (alkyl betaines, amide betaines, sulfobetaines, etc.) , Amphoteric surfactants such as acylmethyltaurine, sorbitan fatty acid esters (such as sorbitan monostearate, sorbitan sesquioleate), glycerin fatty acids (such as glyceryl monostearate), propylene glyco Fatty acid esters (such as propylene glycol monostearate), hydrogenated castor oil derivatives, glycerin alkyl ether, POE sorbitan fatty acid esters (such as POE sorbitan monooleate, polyoxyethylene sorbitan monostearate), POE sorbite fatty acid esters ( POE-sorbitol monolaurate, etc.), POE glycerin fatty acid esters (POE-glycerin monoisostearate, etc.), POE fatty acid esters (polyethylene glycol monooleate, POE distearate, etc.), POE alkyl ethers (POE2-octyldodecyl ether) Etc.), POE alkyl phenyl ethers (POE nonyl phenyl ether, etc.), Pluronic types, POE / POP alkyl ethers (POE / POP2- Siltetradecyl ether), tetronics, POE castor oil / hardened castor oil derivatives (POE castor oil, POE hardened castor oil, etc.), sucrose fatty acid esters, nonionic surfactants such as alkyl glucoside, polyethylene glycol, Glycerin, 1,3-butylene glycol, erythritol, sorbitol, xylitol, maltitol, propylene glycol, dipropylene glycol, diglycerin, isoprene glycol, 1,2-pentanediol, 1,2-hexylene glycol, 1,2- Polyhydric alcohols such as octanediol, moisturizing ingredients such as sodium pyrrolidonecarboxylate, lactic acid, sodium lactate, guar gum, quince seed, carrageenan, galactan, gum arabic, pectin, mannan, starch, xanthan Tangam, curdlan, methylcellulose, hydroxyethylcellulose, carboxymethylcellulose, methylhydroxypropylcellulose, chondroitin sulfate, dermatan sulfate, glycogen, heparan sulfate, hyaluronic acid, sodium hyaluronate, tragacanth gum, keratan sulfate, chondroitin, mucoitin sulfate, hydroxyethyl guar gum, Carboxymethyl guar gum, dextran, keratosulfuric acid , locust bean gum , succinoglucan , carolinic acid , chitin , chitosan, carboxymethylchitin, agar, carboxyvinyl polymer, sodium polyacrylate, polyethylene glycol, bentonite, etc. Can be illustrated.

Furthermore, in addition to the above the powder, Yoima be surface treated squid, talc, kaolin, synthetic mica, magnesium carbonate, aluminum oxide, powder such may base be surface treated such as barium sulfate Ngara, yellow iron oxide, black iron oxide, cobalt oxide, ultramarine, iron blue, titanium oxide, inorganic pigments zinc oxide, good cloud base titanium be surface treated, Sakanarinhaku, pearl agent such as bismuth oxychloride s, laked unprotected red No. 202 also red No. 228, red No. 226, yellow No. 4, blue No. 404, yellow No. 5, red No. 505, 230 red No., red 223 No., No. 201 orange red Organic dyes such as No. 213, Yellow No. 204, Yellow No. 203, Blue No. 1, Green No. 201, Purple No. 201, Red No. 204, paraaminobenzoic acid type UV absorber, anthranilic acid type UV absorber Agent, salicylic acid UV absorber, cinnamic acid UV absorber, benzophenone UV absorber, sugar UV absorber, 2- (2'-hydroxy-5'-t-octylphenyl) benzotriazole, 4-methoxy- UV absorbers such as 4'-t-butyldibenzoylmethane , lower alcohols such as ethanol and isopropanol, vitamin A or derivatives thereof, vitamin B ₆ hydrochloride, vitamin B ₆ tripalmitate, vitamin B ₆ dioctanoate , vitamin B ₂ or derivatives thereof, vitamin B _12, vitamin B such as vitamin B ₁₅ or a derivative thereof, alpha-tocopherol, beta-tocopherol, .gamma.-tocopherol, vitamin E such as vitamin E acetate, vitamin D, vitamin H, Vitamins such as pantothenic acid, panthetin, pyrroloquinoline quinone It can Mashiku example. Among these, particularly preferred, Yoima squid be surface treated, talc, kaolin, synthetic mica, magnesium carbonate, aluminum oxide, may be treated powder such as barium sulfate, surface Baie Ngara, yellow iron oxide, black iron oxide, cobalt oxide, ultramarine, iron blue, titanium oxide, particulate materials such as inorganic pigments zinc oxide can be preferably exemplified.

Antibacterial and antiseptics include paraoxybenzoic acid alkyl esters, benzoic acid, sodium benzoate, sorbic acid, potassium sorbate, phenoxyethanol, etc. Antibacterial agents include benzoic acid, salicylic acid, carboxylic acid, sorbic acid, paraoxybenzoic acid alkyl Preferred examples include esters, parachlorometacresol, hexachlorophene, benzalkonium chloride, chlorhexidine chloride, trichlorocarbanilide, triclosan, photosensitizer, and phenoxyethanol. The composition of the present invention can be produced by treating such essential components and optional components according to a conventional method.

Hereinafter, the present invention will be described in more detail with reference to examples, but it is needless to say that the scope of the present invention is not limited only to such examples.

<Example 1>
According to the following prescription / method, a composition 1 for preparing a skin replica, which is a solidifying skin adhesive composition of the present invention, was prepared. That is, the formulation components were well kneaded at 80 ° C., mixed, stirred and cooled, and degassed under reduced pressure to obtain the composition 1 for skin replica production of the present invention.

<Reference Example 1>
Follow the prescription and method described below, it is a solid-resistant skin adhesive composition of Reference Example was prepared composition 2 for producing skin replica. That is, the formulation components were well kneaded at 80 ° C., mixed, stirred and cooled, and degassed under reduced pressure to obtain Composition 2 for skin replica production of Reference Example .

<Reference Example 2>
Follow the prescription and method described below, is a solid-resistant skin adhesive composition of Reference Example, the composition was made 3 for producing skin replica. That is, the formulation components were well kneaded at 80 ° C., mixed, stirred and cooled, and degassed under reduced pressure to obtain Composition 3 for skin replica production of Reference Example .

<Comparative Example 1>
Comparative composition 1 for preparing a skin replica of a comparative example was prepared according to the following prescription / method. That is, the formulation components were kneaded well at 80 ° C., mixed, stirred and cooled, and degassed under reduced pressure to obtain a comparative composition 1 for making a skin replica of a comparative example.

<Test Example 1>
After applying the composition 1 to 3 and the comparative composition 1 to the cheek of the subject, the solidification / curing time was measured. Moreover, it peeled about 4 minutes after solidification and hardening were confirmed, and the replica of the skin was produced. The evaluation of the skin replica was performed by three professional evaluators according to the following evaluation items.
Solidification hardening time (5 = less than 5 minutes, 4 = 5-8 minutes, 3 = 8-11 minutes, 2 = 11-15 minutes, 1 = 15 minutes or more)
Ease of peeling (5 = very easy, 4 = easy, 3 = useable level, 2 = difficult to peel, 1 = replica remains on skin and cannot be used)
Fine structure (5 = very clear, 4 = clear, 3 = level that can be used, 2 = partially unclear, 1 = unclear / unusable)
Film strength and uniformity (5 = very strong and uniform, 4 = strongly uniform, 3 = no problem in use, 2 = partially weak and uneven part, 1 = unusable)

1 to 3 show replica images of Example 1 and Reference Examples 1 and 2 , and FIG. 4 shows a replica image of Comparative Example 1. The evaluation results of the skin replica are shown in Table 1. In Example 1 and Reference Examples 1 and 2 , a skin replica can be collected in a short time of about 1/3 to 2/3 compared to Comparative Example 1 (Table 1), and the enlarged image is also compared with Comparative Example 1. As a result, a remarkably clear fine structure was exhibited (FIGS. 1 to 4). Among Example 1 and Reference Examples 1 and 2 produced this time, Example 1 had the most excellent effects in solidification / curing time, ease of peeling, microstructure, and film strength / uniformity.

< Example 2 >
In accordance with the following prescription / method, a composition 4 for preparing a skin replica, which is a solidifying skin adhesive composition of the present invention, was prepared. That is, the formulation components were well kneaded at 80 ° C., mixed, stirred and cooled, and degassed under reduced pressure to obtain Composition 4 for skin replica production of the present invention.

<Test Example 2>
Using the composition 4 and the comparative composition 1, skin replicas were produced and evaluated in the same manner as in Test Example 1.

  The evaluation results of the skin replica are shown in Table 2. In the composition 4 prepared using a commercially available silicone emulsion, the composition 1 was excellent in terms of solidification / curing time, ease of peeling, fine structure, and film strength / uniformity. Had an effect.

< Reference Example 3 >
In the same manner as in Example 1, according to the following formulation, a composition 5 for preparing a skin replica, which is a solidifying skin adhesive composition of Reference Example , was prepared. Table 3 shows the solidification / curing time, ease of peeling, microstructure, and film strength. It can be seen that it is preferable to prepare and contain a silicone emulsion in advance.

The present invention can be applied to a replica used for counseling.

It is a figure which shows the skin replica image of Example 1 of this invention (drawing substitute photograph). It is a figure which shows the skin replica image of the reference example 1 of this invention (drawing substitute photograph). It is a figure which shows the skin replica image of the reference example 2 of this invention (drawing substitute photograph). It is a figure which shows the skin replica image of the comparative example 1 (drawing substitute photograph).

Claims (6)

A solidifying skin adhesive composition comprising a water-soluble polymer, 5 to 15% by mass of one or more selected from the following spherical powders, and a silicone emulsion: .
(Powder) Silica, nylon powder, calcium silicate, calcium carbonate, acrylic resin powder which may have a hollow structure, polyethylene powder, high polymerization degree methylpolysiloxane, methylpolysiloxysilicate, methylsiloxane network weight Coalescence   The solidifying skin pressure-sensitive adhesive composition according to claim 1, wherein the water-soluble polymer is polyvinyl alcohol and polyvinyl pyrrolidone in which some or all of the hydroxyl groups may be acetylated. The solidifying skin adhesive composition according to claim 1 or 2 , wherein the spherical powder has a particle size of 1 to 20 µm. The solidifying skin adhesive composition according to any one of claims 1 to 3 , wherein the silicone emulsion is an emulsion of dimethicone and / or cyclomethicone. The solidifying skin pressure-sensitive adhesive composition according to any one of claims 1 to 4 , wherein a content of silicone contained in the silicone emulsion is 1 to 4% by mass relative to a total amount of the composition. The solidifying skin adhesive composition according to any one of claims 1 to 5 , wherein the solid shape of the skin is to be transferred.

Images