JP5319239B2 - Specimen processing apparatus and specimen aspirating apparatus - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a specimen treatment apparatus and a specimen suction apparatus for accurately inserting a suction pipe into a specimen vessel at the center axis, regardless of the magnitude of the outside diameter of the specimen vessel. <P>SOLUTION: A blood analyzer 1 (specimen treatment apparatus) comprises: a first specimen-setting section 255a for holding a long vial 101; a pair of chuck sections 271, having a pair of side faces 271a, facing each other and holding the long vial 101 between them; a stepping motor 274 for making both chuck sections 271 move closely, in a state where the center position O1 of a region held in between a pair of the side faces 271a is maintained at a predetermined position, and holding the long vial 101 held in a holding hole 255j by a pair of the side faces 271a; a timing belt 275; a pulley 276; a specimen suction section 21 for sucking the blood within the long vial 101; and a sample-preparing section 22 for preparing a detection sample. <P>COPYRIGHT: (C)2010,JPO&amp;INPIT

Description

  The present invention relates to a specimen processing apparatus and a specimen aspirating apparatus, and more particularly, to a specimen processing apparatus and a specimen aspirating apparatus for aspirating a specimen by inserting a suction tube into the specimen container.

  Conventionally, a sample processing apparatus that sucks a sample by inserting a suction tube into the sample container is known (see, for example, Patent Document 1).

  In Patent Document 1, a sample container setting section (sample container setting section) for holding a sample container, a movable positioning piece (container holding member) provided in the sample container setting section, and a predetermined position of the apparatus are fixed. In addition, a sample analyzer (sample processing apparatus) including a fixed positioning piece (container holding member) and an aspirating unit (specimen aspirating unit) including a suction tube is disclosed. In this sample analyzer, by moving the sample container setting portion toward the fixed positioning piece, the movable positioning piece holds the sample container held by the sample container setting portion so as to press the sample container toward the fixed positioning piece. It is configured. Then, with the sample container held between the movable positioning piece and the fixed positioning piece, a suction tube is inserted into the sample container and the sample is aspirated.

JP 2007-139462 A

  However, in the sample analyzer (sample processing apparatus) described in Patent Document 1, the movable positioning piece moves and clamps the sample container so as to press the sample container toward the fixed positioning piece fixed at a predetermined position. When the outer diameter of the container is increased or decreased, there is a disadvantage that the position of the center axis of the sample container to be held is shifted in a direction away from the fixed positioning piece or a direction close to the fixed positioning piece. For this reason, it is considered difficult to accurately insert the suction tube at the position of the central axis of the sample containers having different outer diameters.

The present invention has been made to solve the above-described problems, and one object of the present invention is to provide a sample container setting unit in a state where the sample container is accommodated in the hole of the sample container setting unit. Specimen processing device that can accurately insert the aspiration tube into the central axis of the specimen container regardless of the outer diameter of the specimen container even when moved horizontally from the set position to the aspiration position And providing a sample aspiration device.

Means for Solving the Problems and Effects of the Invention

To achieve the above object, a sample processing apparatus according to a first aspect of the present invention includes a sample container setting section having a hole for accommodating the sample container, the sample container setting section hole accommodated sample container of the Insert the suction tube into the sample container through the opening and suck the sample in the sample container, the set position where the sample container is set in the hole of the sample container setting part, and the sample by the sample suction part A sample container set part moving part for horizontally moving the sample container set part and a sample container accommodated in the hole part of the sample container set part moved to the aspiration position a pair of container clamping members which pair of holding portions are disposed so as to face each other, the center position of the region sandwiched by the pair of holding portions in a state of being maintained at a predetermined position, both a pair of container clamping members Sample container set section By the direction orthogonal to the moving direction close to each other by horizontally moving the suction, and the container clamping member driving unit for clamping the accommodated sample container into the hole of the specimen container setting portion to the pair of clip portions, by the sample aspirating section is a sample processing unit for processing specimens were, Bei give a specimen suction unit, in the suction position, is accommodated in the hole of the sample container setting section, and sandwiching state of the specimen container by a pair of container clamping members The sample is aspirated by the aspiration tube.

  In the sample processing apparatus according to the first aspect of the present invention, as described above, both the pair of container clamping members are moved to each other while the center position of the region sandwiched between the pair of clamping parts is maintained at a predetermined position. An area in which the central axis of the specimen container is sandwiched between the pair of sandwiching parts by holding the specimen container held by the holding part between the pair of sandwiching parts, regardless of the outer diameter of the specimen container. Since the sample container is sandwiched between the pair of sandwiching portions while being maintained at the center position (predetermined position), it is possible to prevent the center axis of the sandwiched specimen container from shifting in the moving direction of the pair of container sandwiching members. it can. Thereby, the suction tube can be accurately inserted at the position of the central axis of the sample container.

  In the sample processing apparatus according to the first aspect described above, preferably, the sample container includes a plug that closes the opening, and the sample suction unit plugs the suction tube with the sample container held between the pair of holding units. The aspiration tube is configured to be inserted into the sample container by penetrating through the sample container. If comprised in this way, since the aspiration tube can be penetrated to the stopper while the specimen container is held stably by the clamping part, the specimen container whose opening is blocked by the stopper However, the suction tube can be accurately inserted at the position of the central axis of the sample container.

  In this case, preferably, the sample aspirating unit is configured to pull out the suction tube penetrating the plug body from the plug body in a state in which the clamping of the sample container by the pair of clamping units is released, and the plug body is configured as the suction tube. And a restricting portion for restricting movement in the pull-out direction. According to this configuration, unlike the case where the suction tube penetrating the sample is pulled out while the sample container is sandwiched, the sample container body can move together with the plug body when the suction tube is pulled out from the plug body. Thus, it is possible to suppress the movement of only the plug body from the specimen container body due to the pulling force when the suction tube is pulled out. Moreover, since it can control that a plug body moves to a tension | pulling direction by a control part, a plug body receives the reaction force of the direction opposite to the tension | pulling direction of a suction pipe from a control part. As a result, it is possible to move only the suction tube in the pulling direction while suppressing the force in the direction away from the specimen container body from being applied to the plug, and as a result, the suction tube can be easily pulled out from the plug. it can.

  In the sample processing apparatus according to the first aspect described above, preferably, the pair of holding portions is configured to hold the sample container with four-point support so that the positions of the center axis of the sample container in the front-rear direction and the left-right direction are determined. Has been. With this configuration, by supporting at four points, the center axis of the sample container can be easily positioned in the front-rear direction and the left-right direction regardless of the size of the outer diameter of the sample container. The center axis of the sample container can be easily arranged at the center position of the region sandwiched between the pair of sandwiching portions. Thereby, the suction tube can be easily and accurately inserted into the position of the central axis of the sample container.

  In this case, preferably, in a state where the upright specimen container is sandwiched, each of the pair of sandwiching portions includes a recess formed in a substantially V shape when viewed from above. If comprised in this way, it can be easily clamped by a four-point support with respect to a cylindrical sample container by a pair of clamping part.

The sample processing apparatus according to the first aspect, preferably by close to one another the container clamping member of a pair, the sample container on the vertical line of the predetermined position where the center position of the region sandwiched by the pair of holding portions is located The sample container is moved in the hole so that the central axis is located, and the sample container is held by the holding unit. If comprised in this way, a sample container can be moved within the hole part of a holding | maintenance part, and the center axis | shaft of a sample container can be easily arrange | positioned in the center position of the area | region pinched by a pair of clamping part.

In the sample processing apparatus according to the first aspect, preferably, a sample rack transfer unit that transfers a sample rack that holds a sample container to a sample container extraction position, and a sample rack that is transferred to the sample container extraction position by the sample rack transfer unit taking out the sample container from further comprising a sample container transport section Ru is accommodated in the hole of the sample container setting section. With this configuration, since the sample container is transferred from the sample rack to the sample container setting unit by the sample container transfer unit, the user does not need to set the sample container in the sample container setting unit, thereby reducing the burden on the user. can do.

In the sample processing apparatus according to the first aspect described above, preferably, the sample container setting unit moving unit has a hole in the sample container setting unit on a vertical line at a predetermined position where the center position of the region sandwiched between the pair of holding units is located. center position Before moving the sample container setting section so as to be located. If comprised in this way, since the center position of a holding | maintenance part is arrange | positioned on the vertical line of the center position of the area | region pinched by a pair of clamping part, the area | region where the center axis | shaft of a sample container is pinched | interposed into a pair of clamping part in a holding | maintenance part It can arrange | position to the center position vicinity.

  In the sample processing apparatus according to the first aspect, preferably, the container holding member driving unit includes an annular belt, a belt driving unit that rotates the annular belt in the forward direction and the reverse direction, and a pair of container holding members. A first connecting part for connecting one container holding member to the annular belt, a second connecting part for connecting the other container holding member of the pair of container holding members to the annular belt, and a pulley part for folding the annular belt. In the case where the belt drive unit rotates the annular belt in the forward direction by arranging the pulley unit so that the portion between the first coupling unit and the second coupling unit of the annular belt is attached. When the pair of container holding members are close to each other and the belt driving unit rotates the annular belt in the reverse direction, the pair of container holding members are separated from each other. If comprised in this way, since a pair of container clamping member is moved so that it may adjoin and separate mutually with rotation of one annular belt, each operation | movement of a pair of container clamping member can be easily carried out. Can be synchronized. Moreover, the proximity | contact operation | movement and separation | spacing operation | movement of a pair of container clamping member can be performed using only one drive source (belt drive part).

  In the sample processing apparatus according to the first aspect, preferably, the container holding member driving unit is configured to bring the pair of container holding members close to each other while moving them at the same speed. If comprised in this way, a pair of container clamping member can be mutually adjoined easily in the state which maintained the center position of the area | region pinched by a pair of clamping part in the predetermined position.

In order to achieve the above object, a sample aspirating device according to a second aspect of the present invention includes a sample container setting unit having a hole for storing a sample container, and a sample stored in the hole of the sample container setting unit. A sample aspirator that inserts the suction tube into the sample container through the opening of the container and aspirates the sample in the sample container, a set position where the sample container is set in the hole of the sample container set unit, and a sample aspirator The sample container setting unit moving unit that horizontally moves the sample container setting unit and the sample container accommodated in the hole of the sample container setting unit that has been moved to the aspiration position A pair of container holding members arranged so that a pair of holding parts are opposed to each other, and a pair of container holding members in a state where the center position of a region sandwiched between the pair of holding parts is maintained at a predetermined position. Sample container set By the direction orthogonal to the moving direction of the parts by horizontally moving to close to each other, comprising a container clamping member driving unit for clamping the accommodated sample container into the hole of the specimen container setting portion to the pair of holding portions, and The sample aspirating unit aspirates the sample in the sample container that is accommodated in the hole of the sample container setting unit and is sandwiched between the pair of container sandwiching members at the suction position.

  In the sample suction device according to the second aspect of the present invention, as described above, both the pair of container clamping members are moved to each other while the center position of the region sandwiched between the pair of clamping parts is maintained at a predetermined position. An area in which the central axis of the specimen container is sandwiched between the pair of sandwiching parts by holding the specimen container held by the holding part between the pair of sandwiching parts, regardless of the outer diameter of the specimen container. Since the sample container is sandwiched between the pair of sandwiching portions while being maintained at the center position (predetermined position), it is possible to prevent the center axis of the sandwiched specimen container from shifting in the moving direction of the pair of container sandwiching members. it can. Thereby, the suction tube can be accurately inserted at the position of the central axis of the sample container.

  DESCRIPTION OF THE PREFERRED EMBODIMENTS Embodiments embodying the present invention will be described below with reference to the drawings.

  FIG. 1 is a perspective view showing the overall configuration of a blood analyzer according to an embodiment of the present invention. 2 to 21 are diagrams for explaining the details of each part of the blood analyzer according to the embodiment shown in FIG. First, with reference to FIGS. 1-21, the whole structure of the blood analyzer 1 by one Embodiment of this invention is demonstrated. In the present embodiment, a case where the present invention is applied to a blood analyzer that is an example of a sample processing apparatus will be described.

  In this embodiment, as shown in FIGS. 5 and 6, the sample container 100 for storing blood as a specimen is a long vial 101 (FIG. 5) which is a vertically long specimen container having a rubber sealing lid 101a. And a microtube 102 (see FIG. 6) that is a sample container that is smaller than the long vial 101 and mainly contains a small amount of sample. In the description of the present embodiment, in the case where both the long vial 101 and the microtube 102 are applicable, it is described as the “sample container 100” in the sense that both the long vial 101 and the microtube 102 are included. In the case where only one of the tubes 102 is applicable, the description will be made using the “long vial 101” or the “microtube 102”.

  As shown in FIGS. 1 and 2, the blood analyzer 1 according to the present embodiment includes two measurement units, a first measurement unit 2 and a second measurement unit 3, and a first measurement unit 2 and a second measurement unit 3. From a sample transport device (sampler) 4 arranged on the front side (arrow Y1 direction side) and a PC (personal computer) electrically connected to the first measurement unit 2, the second measurement unit 3, and the sample transport device 4 The control device 5 is provided. The blood analyzer 1 is connected to a host computer 6 (see FIG. 3) by a control device 5.

  In addition, as shown in FIGS. 1 to 4, the first measurement unit 2 and the second measurement unit 3 are substantially the same type of measurement unit, and are arranged adjacent to each other. Specifically, in the present embodiment, the second measurement unit 3 uses the same measurement principle as the first measurement unit 2 to measure the sample for the same measurement item. Furthermore, the second measurement unit 3 also measures measurement items that the first measurement unit 2 does not analyze. Further, as shown in FIG. 3, the first measurement unit 2 and the second measurement unit 3 respectively include sample suction units 21 and 31 for sucking blood as a sample from a sample container (test tube) 100, and a sample suction unit. Sample preparation units 22 and 32 that prepare detection samples from blood aspirated by 21 and 31; and detection units 23 and 33 that detect blood cells of blood from the detection samples prepared by sample preparation units 22 and 32 It is out.

  The first measurement unit 2 and the second measurement unit 3 include unit covers 24 and 34 for accommodating the sample aspirating units 21 and 31, the sample preparation units 22 and 32, and the sample container 100 for the unit cover 24, respectively. And 34, and sample container transport units 25 and 35 for transporting the sample container 100 to the suction positions 600 and 700 (see FIG. 3) by the sample suction units 21 and 31, and the sample container transport units 25 and 35. It further includes presence / absence detection units 26 and 36 for detecting the presence / absence of the long vial 101 to be conveyed, and fixed holding units 27 and 37 for holding the long vial 101 at the suction positions 600 and 700 (see FIG. 3). Further, as shown in FIGS. 1 and 2, on the outer surfaces of the front portions 241 and 341 of the unit covers 24 and 34, the sample set portion opening / closing buttons 28 and 38, the priority sample measurement start buttons 29 and 39, respectively. Openings 241a and 341a through which moving parts 255d and 355d (described later) of the sample container transport parts 25 and 35 pass are provided.

  As shown in FIG. 7, the sample aspirating unit 21 (31) includes a piercer 211 (311) and a piercer moving unit 212 (312). The piercer 211 (311) is formed so that the tip can penetrate a sealing lid 101a (see FIG. 5), which will be described later, of the long vial 101. Piercer moving unit 212 (312) has a function of moving piercer 211 (311) in the vertical direction (in the directions of arrows Z1 and Z2). The piercer moving unit 212 (312) includes a horizontal arm 213 (313) that fixes and holds the piercer 211 (311), and a screw shaft 214 (314) that penetrates the horizontal arm 213 (313) in the vertical direction (arrow Z1 and Z2 directions). ) And a nut 215 (315) screwed into the screw shaft 214 (314). Further, the piercer moving part 212 (312) is slidably attached to the slide rail 216 (316) disposed parallel to the screw shaft 214 (314) (in the directions of arrows Z1 and Z2) and the slide rail 216 (316). The sliding member 217 (317) and the stepping motor 218 (318) are provided. Further, the horizontal arm 213 (313) is fixed to the nut 215 (315) and the sliding member 217 (317).

  A pulley 214a (314a) is attached to the upper end of the screw shaft 214 (314). A pulley 218a (318a) is attached to the output shaft of the stepping motor 218 (318). An annularly formed timing belt 219 (319) is rotatably stretched between the pulley 214a (314a) and the pulley 218a (318a). As a result, the rotational drive of the stepping motor 218 (318) is transmitted to the screw shaft 214 (314) via the timing belt 219 (319) and the screw shaft 214 (314) is rotated, whereby the horizontal arm 213 (313). ) Is moved in the vertical direction (arrow Z1 and Z2 directions). As the horizontal arm 213 (313) moves in the vertical direction (arrows Z1 and Z2), the piercer 211 (311) is moved in the vertical direction (arrows Z1 and Z2).

  The stepping motor 218 (318) is configured to be able to vary the rotational torque according to the supplied current value (the magnitude of the drive pulse). Further, the stepping motor 218 (318) is configured to step out when a load greater than the rotational torque of the motor is applied. Specifically, when the stepping motor 218 (318) sucks blood stored in the microtube 102 (see FIG. 6), the stepping motor 218 (318) sucks blood stored in the long vial 101 (see FIG. 5). In contrast, the rotation torque is controlled to be small, and the step is performed when the tip of the piercer 211 (311) comes into contact with the bottom of the microtube 102. Thereby, even if the tip of the piercer 211 (311) comes into contact with the bottom of the microtube 102, it is possible to prevent the microtube 102 from being damaged. In addition, by allowing the tip of the piercer 211 (311) to reach the bottom of the microtube 102, the sample aspirated portion 21 (31) can aspirate the sample accommodated in the microtube 102 with a small accommodation capacity without substantial waste. Is possible.

  When sucking blood stored in the long vial 101 having a larger storage capacity than the microtube 102, the stepping motor 218 (318) lowers the piercer 211 (311) with a predetermined rotational torque, and the piercer 211 ( 311) is configured to penetrate through the sealing lid 101a. The stepping motor 218 (318) is configured to lower the piercer 211 (311) until the tip reaches the vicinity of the bottom of the long vial 101. In this case, unlike the case of the microtube 102, the movement of the piercer 211 (311) is stopped immediately before the tip comes into contact with the bottom of the long vial 101. Therefore, when the blood stored in the long vial 101 is aspirated, the piercer 211 (311) is not brought into contact with the bottom of the long vial 101, so that the long vial 101 is not damaged by the piercer 211 (311). Further, the stepping motor 218 (318) is configured such that the rotation speed is varied according to the frequency of the drive pulse. Further, the sample aspirating unit 21 (31) is configured to move the piercer 211 (311) upward after returning the blood to the original position.

  The detection unit 23 (33) performs RBC detection (detection of red blood cells) and PLT detection (detection of platelets) by the sheath flow DC detection method, and also performs HGB detection (detection of hemoglobin in the blood) by the SLS-hemoglobin method. It is configured as follows. The detection unit 23 (33) is also configured to perform WBC detection (detection of white blood cells) by a flow cytometry method using a semiconductor laser.

  The detection result obtained by the detection unit 23 (33) is transmitted to the control device 5 as sample measurement data (measurement result). This measurement data is data that is the basis of the final analysis results (red blood cell count, platelet count, hemoglobin content, white blood cell count, etc.) provided to the user.

  As shown in FIG. 4, the sample container transport unit 25 (35) (see FIG. 3) has a hand unit 251 (351) that can hold the long vial 101 and an opening / closing unit that opens and closes the hand unit 251 (351). Part 252 (352), a vertical movement part 253 (353) for linearly moving the hand part 251 (351) in the vertical direction (arrows Z1 and Z2 directions), and a hand part 251 (351) in the vertical direction (arrows Z1 and Z2). And a stirring unit 254 (354) that moves in a pendulum shape in the direction). Further, as shown in FIG. 3, the sample container transport unit 25 (35) includes a sample container transfer unit 255 (355) that moves the sample container 100 substantially horizontally in the directions of arrows Y1 and Y2, and a barcode reading unit 256. (356).

  The hand unit 251 (351) is disposed above the transport path of the rack 110 that the sample transport device 4 transports. Further, the hand unit 251 (351) moves downward (in the direction of arrow Z2) when the long vial 101 is transported to a first extraction position 43a and a second extraction position 43b (see FIG. 3) described later by the sample transport device 4. After the movement, the long vial 101 accommodated in the rack 110 is grasped by being opened and closed by the opening and closing parts 252 and 352.

  The hand unit 251 (351) moves the gripped long vial 101 upward (in the direction of arrow Z1) to take out the long vial 101 from the rack 110, and then is moved in a pendulum shape by the stirring unit 254 (354). (For example, 10 round trips). Thereby, the hand part 251 (351) can stir the blood in the long vial 101 to be grasped. Further, after the stirring is completed, the hand unit 251 (351) is configured to release the grip of the long vial 101 by the opening / closing unit 252 (352) after moving downward (in the direction of arrow Z2). Specifically, the hand unit 251 (351) is moved to the first sample setting unit 255a (355a) moved to the sample setting position 610 (710) (see FIG. 3) by the sample container transfer unit 255 (355). The vial 101 is configured to be set. As shown in FIG. 3, the first extraction position 43a and the sample setting position 610 are arranged so as to overlap each other in plan view, and the second extraction position 43b and the sample setting position 710 are They are arranged so as to overlap.

  The opening / closing part 252 (352) is configured to open and close the hand part 251 (351) so as to hold the long vial 101 by the power of the air cylinder 252a (352a).

  The vertical moving unit 253 (353) is configured to move the hand unit 251 (351) in the vertical direction (arrow Z1 and Z2 directions) along the rail 253b (353b) by the power of the stepping motor 253a (353a). ing.

  The stirring unit 254 (354) is configured to move the hand unit 251 (351) in a pendulum shape in the vertical direction (in the directions of arrows Z1 and Z2) by power from a stepping motor (not shown).

  As shown in FIGS. 8 and 9, the sample container transfer unit 255 (355) includes the first sample setting unit 255a (355a) and the front side (arrow Y1 direction side) of the first sample setting unit 255a (355a). A second sample setting unit 255b (355b) arranged in the above, a moving unit 255d (355d) to which these two sample setting units are attached via an adapter 255c (355c), and a stepping motor 255e (355e) (see FIG. 9). ) And an annular timing belt 255f (355f) (see FIG. 9).

  Also, as shown in FIG. 9, a pulley 255g (355g) is attached to the output shaft of the stepping motor 255e (355e). The timing belt 255f (355f) is rotatably stretched by a pulley 255g (355g) and a pulley 255h (355h) provided on the front side (arrow Y1 direction side) of the stepping motor 255e (355e). ing. Thus, when the stepping motor 255e (355e) is rotationally driven, the timing belt 255f (355f) is rotated between the pulley 255g (355g) and the pulley 255h (355h). Further, a part of the timing belt 255f (355f) is arranged to extend in the front-rear direction (arrow Y1 and Y2 directions), and the moving part 255d (355d) is an attachment part 255i (355i) in the vicinity of the rear end part. Accordingly, the timing belt 255f (355f) is attached to a portion arranged to extend in the front-rear direction. As a result, the moving unit 255d (355d) can be moved in the front-rear direction (arrow Y1 and Y2 directions) as the timing belt 255f (355f) rotates.

  Then, the sample container transfer unit 255 (355) controls the rotational driving of the stepping motor 255e (355e), thereby the first sample setting unit 255a (355a) attached to the moving unit 255d (355d) and the second sample setting unit 255a (355a). It is possible to move the sample setting unit 255b (355b) to a predetermined position according to the measurement processing operation. Specifically, the sample container transfer unit 255 (355) causes each sample setting unit to be changed to the aspiration position 600 (700), the sample setting position 610 (710), and the priority sample setting position 620 (720) shown in FIG. And the test tube presence / absence detection position 630 (730). Further, when the sample container transfer unit 255 (355) transfers the first sample setting unit 255a (355a) to the suction position 600 (700), the sample container transfer unit 255 (355) has a plan view of the first sample setting unit 255a (355a). A center position O2 (see FIG. 3) of a holding hole 255j (355j) to be described later is arranged on a vertical line of a center position O1 (see FIGS. 3, 15, and 16) of a region sandwiched by a pair of side surfaces 271a (371a). It is configured as follows.

  Further, as shown in FIG. 3, the sample container transfer unit 255 (355) is arranged so that the moving unit 255d (355d) intersects the transport path of the rack 110 transported by the sample transport device 4 in plan view. The sample setting unit is configured to move to a predetermined position by passing over the transport path of the rack 110. Specifically, as illustrated in FIG. 10, the moving unit 255d (355d) is disposed at a position H1 higher than the upper end position H2 of the rack 110 that is transported by the sample transport device 4, and is substantially in the horizontal direction. It is comprised so that it may move to the front-back direction (arrow Y1 and Y2 direction). Thereby, it is possible to transport each sample setting unit attached to the moving unit 255d (355d) to a predetermined position while continuing the transport operation of the rack 110 by the sample transport device 4.

  As shown in FIG. 8, the first sample setting portion 255a (355a) has a holding hole 255j (355j), and is configured to hold the long vial 101 (see FIG. 5) in the holding hole 255j (355j). Yes. Further, the holding hole 255j (355j) is formed so that the inner diameter is larger than the outer diameter of the long vial 101, as shown in FIG. That is, the long vial 101 is movably held by the holding hole 255j (355j). Further, the holding hole 255j (355j) is formed in a circular shape when viewed in a plan view (as viewed from the direction of the arrow Z1), and has a substantially rectangular shape when viewed in a cross section as shown in FIG. Is formed. Further, a cutout portion 255k (355k) is formed on the side surface of the first sample setting portion 255a (355a) on the rear side (arrow Y2 direction side) so that the holding hole 255j (355j) is opened. Accordingly, it is possible to visually recognize the barcode 101b (see FIG. 5) attached to the long vial 101 from the outside in a state where the long vial 101 is held by the first sample setting unit 255a (355a). The first sample setting unit 255a (355a) is detachably attached to the adapter 255c (355c), and can be replaced with another first sample setting unit according to the type of the long vial 101.

  As shown in FIG. 8, the second sample setting unit 255b (355b) includes an upper holding unit 255l (355l) and a lower holding unit 255m (355m). The second sample setting unit 255b (355b) holds the upper side of the microtube 102 (see FIG. 6) by the upper holding unit 255l (355l), and the microtube 102 (see FIG. 6) by the lower holding unit 255m (355m). By holding the lower side, the microtube 102 is held at two places having different heights. Thereby, the microtube 102 can be held in a stable state. A holding hole 255n (355n) is formed in the upper holding part 255l (355l), and the upper holding part 255l (355l) is placed in the left-right direction (arrows X1 and X2) at the front and rear portions of the holding hole 255n (355n). A separation portion 255o (355o) that is divided into two in the direction) is formed. And the part divided | segmented into two right and left is each supported by the two support parts 255p (355p) which can be elastically deformed to an outer side direction. As a result, when the support portion 255p (355p) that supports the left and right divided portions is bent outward, the inner diameter of the holding hole 255n (355n) can be changed, so a plurality of different sizes It becomes possible to hold the types of microtubes 102.

  Further, the lower holding part 255m (355m) has a holding hole 255q (355q) at a position corresponding to the position of the holding hole 255n (355n) of the upper holding part 255l (355l) in a plan view. The lower end portion of the microtube 102 is configured to be held in a state where the lower end portion of the 102 is inserted into the holding hole 255q (355q). In addition, the second specimen setting portion 255b (355b) is detachably attached to the adapter 255c (355c), and can handle a type of microtube 102 that cannot be handled by the bending deformation of the support portion 255p (355p). As such, it can be replaced with another second sample setting unit.

  The barcode reading unit 256 (356) is configured to read a barcode 101b attached to each long vial 101 as shown in FIG. The barcode reading unit 256 (356) is configured to read the barcode 101b while rotating the target long vial 101 in the horizontal direction while being held by the first sample setting unit 255a (355a) by a rotating device (not shown). Has been. Accordingly, even when the barcode 101b of the long vial 101 is attached to the opposite side of the barcode reading unit 256 (356), the barcode 101b is moved to the barcode reading unit by rotating the long vial 101. 256 (356) side. Further, the bar code 101b of each long vial 101 is uniquely assigned to each sample, and is used for managing the analysis result of each sample.

  As shown in FIG. 12, the fixed holding unit 27 (37) is configured to fix and hold the long vial 101 transferred to the suction position 600 (700). Further, as shown in FIG. 13, the fixed holding portion 27 (37) is configured not to be fixedly held with respect to the microtube 102 transferred to the suction position 600 (700). When the microtube 102 is used, the microtube 102 is stably held using the bending deformation of the support portion 255p (355p) of the second sample setting portion 255b (355b) as described above. Therefore, it is not necessary to use the fixed holding portion 27 (37). As shown in FIGS. 12 to 14, the fixed holding portion 27 (37) includes a pair of chuck portions 271 (371), and a slide rail 272 (372) arranged to extend horizontally in the directions of the arrows X 1 and X 2. And a sliding member 273 (373) slidably attached to the slide rail 272 (372). Further, as shown in FIG. 9, the fixed holding portion 27 (37) includes a stepping motor 274 (374), an annular timing belt 275 (375), a plurality of pulleys 276 (376), and a position sensor 277 (377). ).

  As shown in FIGS. 12 to 17, the pair of chuck portions 271 (371) are formed in a substantially V shape when the pair of side surfaces 271 a (371 a) facing each other are viewed in plan (viewed from the direction of the arrow Z 1). Has been. Further, since the pair of side surfaces 271a (371a) are formed in a substantially V shape, as shown in FIG. 17, the long vial 101 is supported by the pair of side surfaces 271a (371a) at four points as viewed in a plan view. Grasped. More specifically, the pair of chuck portions 271 has a thickness of about 5 mm in the vertical direction (the directions of arrows Z1 and Z2), and the long vial 101 is linearly formed in the vertical direction at four points by the pair of side surfaces 271a. It is supported in a line contact state. In addition, the four points where the long vial 101 and the pair of side surfaces 271a (371a) contact each other pass through the center position O1 of the region sandwiched by the pair of side surfaces 271a (371a), and the straight line L1 parallel to the directions of the arrows X1 and X2 They are located symmetrically. The four points are located symmetrically with respect to a straight line L2 passing through the center position O1 and parallel to the directions of the arrows Y1 and Y2. Accordingly, the long vial 101 has a lateral direction so that the central axis P of the long vial 101 is arranged on the vertical line of the center position O1 when viewed in plan even when the outer diameters are different. Positions (in the directions of arrows X1 and X2) and in the front-rear direction (in the directions of arrows Y1 and Y2) are determined.

  As shown in FIGS. 12 to 14, one of the pair of chuck portions 271 (371) is connected to the sliding member 273 (373) and the timing belt 275 (375) by the connecting portion 278a (378a) (see FIG. 12 and FIG. 12). (See FIG. 13). The other of the pair of chuck portions 271 (371) is attached to both the sliding member 273 (373) and the timing belt 275 (375) by a connecting portion 278b (378b). Accordingly, as the timing belt 275 (375) rotates, the pair of chuck portions 271 (371) is moved in the directions of the arrows X1 and X2 together with the sliding member 273 (373). The annular timing belt 275 (375) is configured to rotate while being guided by a plurality of pulleys 276 (376) when the stepping motor 274 (374) is driven to rotate. Further, as shown in FIG. 9, the annular timing belt 275 (375) is tensioned by a plurality of pulleys 276 (376) so as to have a predetermined shape. Specifically, the timing belt 275 (375) is formed such that a portion arranged to extend horizontally in the directions of the arrows X1 and X2 is folded back by a pulley 276 (376) to form two upper and lower stages. . Therefore, when the timing belt 275 (375) rotates, the upper and lower upper and lower portions are moved in directions opposite to each other in the directions of the arrows X1 and X2.

  A connecting portion 278a (378a) attached to one of the pair of chuck portions 271 (371) is fixed to the upper part of two upper and lower stages extending horizontally in the directions of the arrows X1 and X2. A connecting portion 278b (378b) attached to the other of the pair of chuck portions 271 (371) is fixed to the lower portion of the upper and lower two stages extending horizontally in the directions of the arrows X1 and X2. That is, one pulley 276 (so that the portion between the connecting portion 278a (378a) of one chuck portion 271 (371) and the connecting portion 278b (378b) of the other chuck portion 271 (371) is attached is folded back. 376) is arranged. As a result, as shown in FIGS. 15 and 16, the pair of chuck portions 271 (371) are brought close to each other when the timing belt 275 (375) is rotated in the direction of the arrow A2, and the timing belt 275 (375) is provided. ) Are separated from each other when they are rotated in the direction of arrow A1. Further, since the pair of chuck portions 271 (371) are both attached to the common timing belt 275 (375), they move toward and away from each other while moving at the same speed.

  In addition, since the pair of chuck portions 271 (371) is configured as described above, the center position O1 of the region sandwiched between the pair of side surfaces 271a (371a) can be moved while being maintained at substantially the same position. It is. The pair of chuck portions 271 (371) is substantially the same as the lowered position of the piercer 211 (311) where the center position O1 of the region sandwiched between the pair of side surfaces 271a (371a) is lowered in the vertical direction as viewed in a plan view. Are attached to the timing belt 275 (375) via the connecting portions 278a and 278b (378a and 378b) so as to be in the same position. Accordingly, when viewed in plan, the central axis P of the long vial 101 held by the pair of side surfaces 271a (371a) of the pair of chuck portions 271 (371) is substantially at the lowered position of the piercer 211 (311). It is possible to match.

  The position sensor 277 (377) has a notch and is formed in a substantially U shape. Further, the position sensor 277 (377) is configured to detect a connecting portion 278 (378) crossing the notch. Based on the detection result of the position sensor 277 (377) and the stepping number of the stepping motor 274 (374), the CPU 51a of the control device 5 described later can determine the positions of the pair of chuck portions 271 (371). is there.

  As shown in FIGS. 12 to 14, the sealing lid 101 a and the long vial 101 are disposed on the upper surface of the support member 272 a (372 a) having a U-shaped cross section to which the slide rail 272 (372) is attached. A restricting portion 279 (379) that restricts movement in the direction of arrow Z1 is arranged. The movement of the restricting portion 279 (379) in the left-right direction (arrow X1 and X2 directions) is restricted by a positioning member 279a (379a) attached to the upper surface of the support member 272a (372a). The restricting portion 279 (379) is configured to be disposed above the long vial 101 transferred to the suction position 600 (700) by the positioning member 279a (379a). Further, the restricting portion 279 (379) is configured to be slidable in the front-rear direction (arrow Y1 and Y2 directions). Thereby, when a sample adheres to the regulating portion 279 (379), the regulating portion 279 (379) can be slid and removed, washed, or exchanged. Further, as shown in FIG. 12 and FIG. 13, an opening 279b (379b) for penetrating the piercer 211 (311) is formed in the restricting portion 279 (379).

  The sample setting section open / close button 28 (38) is used when measuring a priority sample that is measured in preference to a continuous measurement sample (sample that is continuously measured) stored in the long vial 101 held in the rack 110. In addition, it can be pressed by the user.

  The priority sample measurement start button 29 (39) is configured to be pressed by the user. After the user sets the long vial 101 or the microtube 102 containing the priority specimen in the first specimen setting section 255a (355a) or the second specimen setting section 255b (355b), the priority specimen measurement start button 29 (39) When is pressed, the set long vial 101 or microtube 102 is taken into the measurement unit and measurement is started.

  As shown in FIGS. 4 and 18, the sample transport device 4 holds the pre-analysis rack capable of holding a plurality of racks 110 in which the long vials 101 for storing the samples before the analysis is performed. Unit 41, post-analysis rack holding unit 42 capable of holding a plurality of racks 110 in which long vials 101 for storing samples after analysis are stored, and rack 110 in the directions of arrows X1 and X2 The rack transport unit 43 that moves horizontally linearly, the barcode reading unit 44, the presence / absence detection sensor 45 that detects the presence / absence of the long vial 101 (see FIG. 4), and the rack 110 are moved into the post-analysis rack holding unit. And a rack delivery section 46.

  The pre-analysis rack holding unit 41 includes a rack feeding unit 411. When the rack feeding unit 411 moves in the direction of the arrow Y2, the racks 110 held by the pre-analysis rack holding unit 41 are transported one by one. It is configured to extrude onto the portion 43. The rack feeding unit 411 is configured to be driven by a stepping motor (not shown) provided below the pre-analysis rack holding unit 41. In addition, the pre-analysis rack holding unit 41 has a regulating unit 412 (see FIG. 4) in the vicinity of the rack transporting unit 43, and the rack 110 once pushed onto the rack transporting unit 43 returns to the pre-analysis rack holding unit 41. The movement of the rack 110 is restricted so as not to be performed.

  The post-analysis rack holding unit 42 has a regulating unit 421 (see FIG. 4) in the vicinity of the rack transporting unit 43, and the rack 110 once moved into the post-analysis rack holding unit 42 is not returned to the rack transporting unit 43 side. Thus, the movement of the rack 110 is restricted.

  As shown in FIG. 3, the rack transport unit 43 includes a first extraction position 43 a for providing the sample to the first measurement unit 2 and a second extraction position 43 b for providing the sample to the second measurement unit 3. In addition, the rack 110 is transported to transfer the long vial 101 held in the rack 110. Furthermore, the rack transport unit 43 includes a sample presence / absence confirmation position 43c for the presence / absence detection sensor 45 to confirm the presence / absence of the sample container 100 that accommodates the sample, and a bar of the long vial 101 in which the barcode reading unit 44 accommodates the sample. The rack 110 is transported so that the long vial 101 is transferred to the reading position 43d for reading the code 101b (see FIG. 5).

  As shown in FIGS. 4 and 18, the rack transporter 43 has two belts, a first belt 431 and a second belt 432, which can move independently of each other. Further, the widths b1 and b2 (see FIG. 18) of the first belt 431 and the second belt 432 in the directions of arrows Y1 and Y2 are respectively less than half the width B of the rack 110 in the directions of arrows Y1 and Y2. Thereby, when the rack transport unit 43 transports the rack 110, the first belt 431 and the second belt 432 are both arranged in parallel so as not to protrude from the width B of the rack 110. As shown in FIGS. 19 and 20, the first belt 431 and the second belt 432 are formed in an annular shape so as to surround the rollers 431a, 431b, 431c and the rollers 432a, 432b, 432c, respectively. Has been placed. In addition, the outer circumferences of the first belt 431 and the second belt 432 have inner widths w1 (see FIG. 19) and w2 (see FIG. 19) slightly larger (for example, about 1 mm) than the width W of the rack 110 in the directions of the arrows X1 and X2. 20)), two protrusion pieces 431d and 432d are formed. The first belt 431 moves the outer periphery of the rollers 431a to 431c by the stepping motor 431e (see FIG. 4) while holding the rack 110 inside the protruding piece 431d, thereby moving the rack 110 in the directions of arrows X1 and X2. Configured to move to. Further, the second belt 432 moves the outer periphery of the rollers 432a to 432c by the stepping motor 432e (see FIG. 4) while holding the rack 110 inside the protruding piece 432d, thereby moving the rack 110 to the arrow X1 and It is configured to move in the X2 direction. Further, the first belt 431 and the second belt 432 are configured to be able to move the rack 110 independently of each other.

  The barcode reading unit 44 is configured to read the barcode 101 b of the long vial 101 shown in FIG. 5 and also read the barcode 110 a attached to the rack 110. The barcode reading unit 44 is configured to read the barcode 101b while rotating the target long vial 101 in the horizontal direction while being accommodated in the rack 110 by a rotating device (not shown). Thereby, even when the barcode 101b of the long vial 101 is affixed to the opposite side to the barcode reading unit 44, the barcode 101b can be directed to the barcode reading unit 44 side. Further, the bar code 110a of the rack 110 is uniquely assigned to each rack, and is used for managing the analysis result of the sample.

  The presence / absence detection sensor 45 is a contact-type sensor, and includes a goodwill-shaped contact piece 451 (see FIG. 4), a light emitting element (not shown) that emits light, and a light receiving element (not shown). The presence / absence detection sensor 45 is bent by the contact piece 451 coming into contact with the detection target object, and as a result, the light emitted from the light emitting element is reflected by the contact piece 451 and enters the light receiving element. It is configured as follows. Accordingly, when the detection target long vial 101 accommodated in the rack 110 passes below the presence / absence detection sensor 45, the contact piece 451 is bent by the long vial 101 to detect the presence of the long vial 101. Is possible.

  The rack delivery section 46 is disposed so as to face the post-analysis rack holding section 42 with the rack transport section 43 interposed therebetween, and is configured to move horizontally in the arrow Y1 direction. Accordingly, when the rack 110 is transported between the post-analysis rack holding unit 42 and the rack sending unit 46, the rack 110 is pressed by moving the rack sending unit 46 to the post-analysis rack holding unit 42 side. It is possible to move into the post-analysis rack holder 42.

  As shown in FIGS. 1 to 3 and 21, the control device 5 includes a personal computer (PC) or the like, and includes a control unit 51 (see FIG. 21) including a CPU, ROM, RAM, and the like, a display unit 52, And an input device 53. The display unit 52 is provided to display analysis results obtained by analyzing digital signal data transmitted from the first measurement unit 2 and the second measurement unit 3.

  Further, as shown in FIG. 21, the control device 5 is configured by a computer 500 mainly including a control unit 51, a display unit 52, and an input device 53. The control unit 51 mainly includes a CPU 51a, a ROM 51b, a RAM 51c, a hard disk 51d, a reading device 51e, an input / output interface 51f, a communication interface 51g, and an image output interface 51h. The CPU 51a, ROM 51b, RAM 51c, hard disk 51d, reading device 51e, input / output interface 51f, communication interface 51g, and image output interface 51h are connected by a bus 51i.

  The CPU 51a can execute the computer program stored in the ROM 51b and the computer program loaded in the RAM 51c. The computer 500 functions as the control device 5 when the CPU 51a executes application programs 54a, 54b, and 54c, which will be described later.

  The ROM 51b is configured by a mask ROM, PROM, EPROM, EEPROM, or the like, and stores a computer program executed by the CPU 51a, data used for the same, and the like.

  The RAM 51c is configured by SRAM, DRAM, or the like. The RAM 51c is used to read out computer programs recorded in the ROM 51b and the hard disk 51d. Further, when these computer programs are executed, it is used as a work area of the CPU 51a.

  The hard disk 51d is installed with various computer programs to be executed by the CPU 51a, such as an operating system and application programs, and data used for executing the computer programs. A measurement process (1) program 54a for the first measurement unit 2, a measurement process (2) program 54b for the second measurement unit 3, and a sampler operation process program 54c for the sample transport device 4 are also installed in the hard disk 51d. Yes. By executing these application programs 54a to 54c by the CPU 51a, the operation of each part of the first measurement unit 2, the second measurement unit 3, and the sample transport apparatus 4 is controlled. A measurement result database 54d is also installed in the hard disk 51d.

  The reading device 51e is configured by a flexible disk drive, a CD-ROM drive, a DVD-ROM drive, or the like, and can read a computer program or data recorded on the portable recording medium 54. The portable recording medium 54 stores application programs 54a to 54c. The computer 500 reads the application programs 54a to 54c from the portable recording medium 54, and installs the application programs 54a to 54c in the hard disk 51d. Is possible.

  The application programs 54a to 54c are not only provided by the portable recording medium 54, but also from an external device that is communicably connected to the computer 500 via an electric communication line (whether wired or wireless). It can also be provided through a communication line. For example, the application programs 54a to 54c are stored in the hard disk of a server computer on the Internet, and the computer 500 accesses the server computer to download the application programs 54a to 54c and install them on the hard disk 51d. It is also possible to do.

  In addition, an operating system that provides a graphical user interface environment, such as Windows (registered trademark) manufactured and sold by Microsoft Corporation, is installed in the hard disk 51d. In the following description, the application programs 54a to 54c are assumed to operate on the operating system.

  The input / output interface 51f includes, for example, a serial interface such as USB, IEEE1394, RS-232C, a parallel interface such as SCSI, IDE, IEEE1284, an analog interface including a D / A converter, an A / D converter, and the like. Has been. An input device 53 is connected to the input / output interface 51f, and the user can input data to the computer 500 by using the input device 53.

  The communication interface 51g is, for example, an Ethernet (registered trademark) interface. The computer 500 can transmit and receive data to and from the first measurement unit 2, the second measurement unit 3, the sample transport device 4, and the host computer 6 using a predetermined communication protocol through the communication interface 51g.

  The image output interface 51h is connected to a display unit 52 composed of an LCD or a CRT, and outputs a video signal corresponding to the image data given from the CPU 51a to the display unit 52. The display unit 52 is configured to display an image (screen) according to the input video signal.

  With the above-described configuration, the control unit 51 analyzes the components to be analyzed using the measurement results transmitted from the first measurement unit 2 and the second measurement unit 3, and the analysis results (red blood cell count, platelet count, hemoglobin amount) , White blood cell count, etc.).

  As shown in FIG. 5, the rack 110 is formed with ten container housing portions 110b so that ten long vials 101 can be housed in a row. Each container storage portion 110b is provided with an opening 110c so that the barcode 101b of the stored long vial 101 can be seen.

  22 and 23 are diagrams for explaining the sample aspirating operation of the blood analyzer according to the embodiment shown in FIG. Next, with reference to FIG. 9, FIG. 17, FIG. 22, and FIG. 23, the sample aspirating operation of the blood analyzer 1 according to one embodiment will be described. Since the first measurement unit 2 and the second measurement unit 3 perform sample aspiration by the same operation, the sample aspiration operation by the first measurement unit 2 will be described below, and the sample aspiration by the second measurement unit 3 will be described. A description of the operation is omitted.

  First, the long vial 101 held in the rack 110 is transferred to the first extraction position 43a shown in FIG. 22 by the rack transport unit 43 of the sample transport device 4. The long vial 101 transferred to the first extraction position 43a is moved from the first extraction position 43a to the holding hole 255j of the first sample setting section 255a by the hand unit 251 of the sample container transport section 25 at the sample setting position 610. Be transported. Thereafter, the moving portion 255d is moved rearward (in the direction of arrow Y2) of the apparatus, so that the center position O2 of the holding hole 255j is sandwiched between the pair of side surfaces 271a when viewed in plan (as viewed from the direction of arrow Z1). It is arranged on the vertical line of the center position O1 of the area.

  Next, by driving the stepping motor 274 (see FIG. 9) and rotating the timing belt 275 (see FIG. 9) in the direction of arrow A2 (see FIGS. 15 and 16), the pair of chuck portions 271 is paired. Of the region sandwiched between the side surfaces 271a of each other and approaching each other at the same speed while maintaining the central position O1 at the same position. Then, when the long vial 101 held in the holding hole 255j is sandwiched between the pair of side surfaces 271a, the central axis P of the long vial 101 is arranged on the vertical line of the center position O1 as shown in FIG. Specifically, the long vial 101 held in the holding hole 255j comes into contact with a pair of adjacent side surfaces 271a, and then the central axis P is on the vertical line of the center position O1 as the chuck portion 271 moves close. While being moved in the holding hole 255j so as to be disposed at the position, the pair of side surfaces 271a are gripped. Thereafter, with the long vial 101 held by the pair of side surfaces 271 a, the piercer 211 is lowered, whereby the sealing lid 101 a is penetrated by the piercer 211, and the piercer 211 is inserted into the long vial 101. Specifically, the piercer 211 is lowered by a stepping motor 218 that is rotationally driven with a predetermined rotational torque, and is lowered until the tip reaches the vicinity of the bottom of the long vial 101 after passing through the sealing lid 101a. Then, the blood in the long vial 101 is aspirated by the sample aspirating unit 21.

  When the blood suction is completed, the timing belt 275 is rotated in the arrow A1 direction (see FIGS. 15 and 16) by the stepping motor 274, and the pair of chuck portions 271 are separated from each other. Then, the piercer 211 is raised in a state where the grip of the long vial 101 by the pair of side surfaces 271a is released. At this time, due to the frictional force between the sealing lid 101a and the piercer 211 penetrated, the sealing lid 101a is lifted upward (in the direction of arrow Z1) as the piercer 211 moves upward, as shown in FIG. Further, the container body of the long vial 101 is lifted upward together with the sealing lid 101a because the gripping by the pair of side surfaces 271a is released. The upper surface of the sealing lid 101a raised to a predetermined height is in contact with the restricting portion 279, and the upward movement is restricted. Thereby, since only the piercer 211 can be moved upward, the piercer 211 can be pulled out of the sealing lid 101a. When the piercer 211 is pulled out from the sealing lid 101a, the container body of the sealing lid 101a and the long vial 101 is dropped into the lower holding hole 255j, and the specimen aspirating operation is completed.

  In the present embodiment, as described above, the holding hole is obtained by moving both the pair of chuck portions 271 close to each other while the center position O1 of the region sandwiched between the pair of side surfaces 271a is maintained at a predetermined position. The center of the region where the central axis P of the long vial 101 is sandwiched between the pair of side surfaces 271a regardless of the outer diameter of the long vial 101 by sandwiching the long vial 101 held by 255j between the pair of side surfaces 271a. Since the long vial 101 is sandwiched between the pair of side surfaces 271a while being maintained at the position O1, the center axis P of the sandwiched long vial 101 is shifted in the moving direction (arrow X1 and X2 directions) of the pair of chuck portions 271. Can be suppressed. Thereby, the piercer 211 can be accurately inserted into the long vial 101.

  In this embodiment, the long vial 101 is provided with a sealing lid 101a for closing the opening, and the piercer 211 is passed through the sealing lid 101a while the long vial 101 is sandwiched between the pair of side surfaces 271a. By configuring the specimen aspirating unit 21 to be inserted into the long vial 101, the piercer 211 is penetrated through the sealing lid 101a while the long vial 101 is held stably by the pair of side surfaces 271a. Therefore, the piercer 211 can be inserted into the long vial 101 with high accuracy.

  Further, in the present embodiment, by providing the restriction portion 279 that restricts the movement of the sealing lid 101a in the pulling-out direction (arrow Z1 direction) of the piercer 211, the sealing lid 101a is pulled in the tension direction (arrow Z1 direction) by the restriction portion 279. ) Can be restricted, the sealing lid 101a receives a reaction force from the restriction part 279 in the direction opposite to the pulling direction of the piercer 211 (in the direction of arrow Z2). Accordingly, it is possible to move only the piercer 211 in the pulling direction while suppressing the force in the direction of coming off the container body from being applied to the sealing lid 101a, and as a result, the piercer 211 can be easily pulled out from the sealing lid 101a. Can do.

  Further, in the present embodiment, the long vial 101 is determined so that the positions of the central axis P of the long vial 101 in the front-rear direction (arrow Y1 and Y2 direction) and the left-right direction (arrow X1 and X2 direction) are determined in plan view. By configuring the pair of side surfaces 271a so as to be clamped by four-point support, by supporting at four points, the central axis P of the long vial 101 can be easily obtained regardless of the outer diameter of the long vial 101. Therefore, the center axis P of the long vial 101 can be easily disposed at the center position O1 of the region sandwiched between the pair of side surfaces 271a. Thereby, the piercer 211 can be easily and accurately inserted into the long vial 101.

  Further, in the present embodiment, the pair of side surfaces 271a are formed in a substantially V shape when seen in a plan view, so that the long side wall 271a can be easily separated from the cylindrical long vial 101 by the pair of side surfaces 271a. Can be clamped with point support.

  In this embodiment, the timing belt 275, the stepping motor 274 that rotates the timing belt 275 in the A1 direction and the A2 direction, and one chuck portion 271 of the pair of chuck portions 271 are connected to the timing belt 275. A connecting portion 278a, a connecting portion 278b for connecting the other chuck portion 271 of the pair of chuck portions 271 to the timing belt 275, a pulley 276 for turning back the timing belt 275, and a connecting portion 278a for the timing belt 275 are provided. When the timing belt 275 is rotated in the A2 direction by arranging the pulley 276 so that the portion between the connecting portion 278b and the connecting portion 278b is attached, the pair of chuck portions 271 come close to each other and the timing belt 275 is When rotated in the A1 direction In addition, since the pair of chuck portions 271 are configured to be separated from each other, the pair of chuck portions 271 are moved toward and away from each other as the single timing belt 275 rotates. The operations of the pair of chuck portions 271 can be synchronized. Further, the proximity operation and the separation operation of the pair of chuck portions 271 can be performed using only one stepping motor 274.

  The embodiment disclosed this time should be considered as illustrative in all points and not restrictive. The scope of the present invention is shown not by the above description of the embodiments but by the scope of claims for patent, and further includes all modifications within the meaning and scope equivalent to the scope of claims for patent.

  For example, in the present embodiment, a blood analyzer is shown as an example of a sample processing apparatus. However, the present invention is not limited to this, and any sample processing apparatus that sucks and processes a sample from a sample container, for example, a smear sample. The present invention may be applied to other sample processing apparatuses such as a manufacturing apparatus.

  In the present embodiment, a sample processing apparatus including two measurement units, a first measurement unit and a second measurement unit, is shown as an example of a sample processing apparatus. However, the present invention is not limited to this, and one measurement unit is provided. Or a sample processing apparatus including three or more measurement units.

  In this embodiment, a long vial having a sealing lid as a stopper is shown as an example of a specimen container. However, the present invention is not limited to this, and the specimen container having an opening without having a stopper is provided. May be used.

  In the present embodiment, an example of a configuration in which the restriction portion is provided has been described. However, the present invention is not limited to this, and the plug body is not limited to this and is plugged to another member in the apparatus disposed above the sample container. It is also possible to have a configuration in which the same function as that of the restricting portion is exerted by contacting them.

  Further, in the present embodiment, as an example of the sandwiching portion, the sandwiching portion having the side surface formed in a substantially V shape when seen in a plan view is shown. However, the present invention is not limited to this, and the sample container is supported at four points. As long as it is a clamping part having a shape that can be clamped by, for example, it may be a clamping part having a side surface formed in a substantially U shape when seen in a plan view.

  Further, in the present embodiment, as an example of the clamping unit, the clamping unit having a side surface that clamps the long vial with four-point support as viewed in plan is shown, but the present invention is not limited to this, and the central axis of the sample container As long as the positions in the front-rear direction and the left-right direction are determined, it may be a clamping unit that clamps the sample container with support of five or more points in plan view. In addition, when viewed in a plan view, it may be configured to be supported and held by a line instead of a point. That is, the contact between the clamping unit and the sample container may be any of point contact, line contact, and surface contact.

  Further, in the present embodiment, as an example of the hole portion of the holding portion, the holding hole formed in a circular shape when viewed in plan is shown, but the present invention is not limited thereto, and the sample container can be held movably. As long as it is a hole, it may be a hole formed in a rectangular shape in plan view, or may be a hole formed in a shape other than a circular shape and a rectangular shape.

  Further, in the present embodiment, a pair of chucks is provided by attaching both the connecting part of one chuck part and the connecting part of the other chuck part to a common timing belt and driving a stepping motor. However, the present invention is not limited to this, and the configuration is such that one chuck portion and the other chuck portion are driven so as to approach and separate from each other by separate drive portions. There may be. Further, the drive source is not limited to a motor, and may be a drive source other than a motor such as a syringe pump.

  In the present embodiment, the long vial is held in the holding hole of the first sample setting unit at the sample setting position from the rack transported by the rack transporting unit, and the first sample setting unit holding the long vial is held at the sample aspiration position. However, the present invention is not limited to this, and the chuck unit for holding the long vial is not located at the sample setting position without providing the sample container setting unit moving unit. After the long vial is transferred from the rack transported by the rack transport unit to the holding hole of the sample container setting unit at the sample setting position, the long vial is sandwiched by the chuck unit and the piercer is moved to above the center position of the holding hole. The piercer may be inserted into the long vial.

  Further, in this embodiment, the piercer is pulled out from the sealing lid of the long vial by raising the piercer while the grip of the long vial by the chuck portion is released, but the present invention is not limited to this, and the chuck portion is not limited thereto. The piercer may be pulled out from the sealing lid of the long vial by raising the piercer while the long vial is gripped.

1 is a perspective view showing an overall configuration of a blood analyzer according to an embodiment of the present invention. It is a perspective view for demonstrating the detail of each part of the blood analyzer by one Embodiment shown in FIG. It is the schematic which shows the measurement unit and sample conveyance apparatus of the blood analyzer by one Embodiment shown in FIG. It is a perspective view which shows the measurement unit and sample conveyance apparatus of the blood analyzer by one Embodiment shown in FIG. It is a perspective view which shows the rack and long vial of the blood analyzer by one Embodiment shown in FIG. It is a perspective view which shows the microtube of the blood analyzer by one Embodiment shown in FIG. FIG. 2 is a perspective view showing the vicinity of a specimen aspirating unit of the blood analyzer according to the embodiment shown in FIG. 1. It is a perspective view which shows the sample setting part of the blood analyzer by one Embodiment shown in FIG. It is a perspective view which shows the sample container transfer part and fixed holding | maintenance part vicinity of the blood analyzer by one Embodiment shown in FIG. It is a figure for demonstrating the position of the moving part of the blood analyzer by one Embodiment shown in FIG. It is sectional drawing which shows the 1st sample setting part of the blood analyzer by one Embodiment shown in FIG. It is a perspective view which shows the fixed holding | maintenance part vicinity of the blood analyzer by one Embodiment shown in FIG. It is a perspective view which shows the fixed holding | maintenance part vicinity of the blood analyzer by one Embodiment shown in FIG. It is a front view which shows the fixed holding | maintenance part vicinity of the blood analyzer by one Embodiment shown in FIG. It is a figure for demonstrating the structure of the fixed holding | maintenance part of the blood analyzer by one Embodiment shown in FIG. It is a figure for demonstrating the structure of the fixed holding | maintenance part of the blood analyzer by one Embodiment shown in FIG. It is a figure for demonstrating the structure of the chuck | zipper part of the blood analyzer by one Embodiment shown in FIG. It is a top view for demonstrating the sample conveyance apparatus of the blood analyzer by one Embodiment shown in FIG. It is a side view for demonstrating the sample conveyance apparatus of the blood analyzer by one Embodiment shown in FIG. It is a side view for demonstrating the sample conveyance apparatus of the blood analyzer by one Embodiment shown in FIG. It is a block diagram for demonstrating the control apparatus of the blood analyzer by one Embodiment shown in FIG. It is a figure for demonstrating the sample aspiration operation | movement of the blood analyzer by one Embodiment shown in FIG. It is a figure for demonstrating the sample aspiration operation | movement of the blood analyzer by one Embodiment shown in FIG.

Explanation of symbols

DESCRIPTION OF SYMBOLS 1 Blood analyzer 4 Sample transport apparatus 21, 31 Sample suction part 100 Sample container 101 Long vial 101a Sealing lid 110 Rack 211, 311 Piercer 251, 351 Hand part 255, 355 Sample container transfer part 255a, 355a First sample setting part 255j 355j Holding hole 271, 371 Chuck part 271a, 371a Side face 274, 374 Stepping motor 275, 375 Timing belt 276, 376 Pulley 278a, 378a Connecting part 278b, 378b Connecting part 279, 379 Restricting part

Claims (11)

A sample container setting unit having a hole for accommodating the sample container;
A sample aspirating section for inserting a suction tube into the sample container through an opening of the sample container accommodated in the hole of the sample container setting section, and aspirating the sample in the sample container;
Specimen container set for horizontally moving the specimen container setting part between a setting position where the specimen container is set in the hole of the specimen container setting part and an aspiration position where the specimen is aspirated by the specimen aspirating part Moving part,
A pair of container holding members arranged so that a pair of holding parts for holding the sample container accommodated in the hole of the sample container setting part moved to the suction position are opposed to each other;
While maintaining the center position of the region sandwiched in the pair of holding portions in position, to close to each other by horizontal movement of both of the pair of container clamping members in a direction perpendicular to the moving direction of the sample container setting section A container clamping member driving unit configured to clamp the sample container accommodated in the hole of the sample container setting unit between the pair of clamping units ;
E Bei and a sample processing unit for processing the aspirated sample by the sample suction section,
The sample aspirating unit aspirates the sample in the sample container that is accommodated in the hole of the sample container setting unit and is sandwiched between the pair of container sandwiching members at the suction position by the suction tube. sample processing apparatus. The specimen container includes a plug that closes the opening,
The sample aspirating unit is configured to insert the aspirating tube into the sample container by penetrating the aspirating tube through the plug while the sample container is sandwiched between the pair of clamping units. The sample processing apparatus according to claim 1. The sample aspirating unit is configured to pull out the suction tube penetrating the plug body from the plug body in a state where the clamping of the sample container by the pair of clamping units is released,
The sample processing apparatus according to claim 2, further comprising a regulating unit that regulates movement of the plug body in the drawing direction of the suction tube.   The pair of clamping parts are configured to clamp the sample container with four-point support so that the positions of the central axis of the sample container in the front-rear direction and the left-right direction are determined. 2. The sample processing apparatus according to claim 1.   5. The sample processing apparatus according to claim 4, wherein, in a state in which the upright sample container is held, each of the pair of holding portions includes a concave portion formed in a substantially V shape when viewed from above. By approaching pre Symbol pair of container clamping members together, wherein the sample container so that the center axis of the specimen container on the vertical line of the predetermined position where the center position of the region sandwiched in the pair of holding portions is located is located 6. The sample processing apparatus according to claim 1, wherein the sample container is configured to be moved in the hole portion and to hold the sample container by the holding portion. A sample rack transfer section for transferring a sample rack holding the sample container to a sample container extraction position;
The sample rack by the transfer unit takes out the sample container from the transported sample rack to the specimen container retrieving position, further comprising said specimen container transferring unit Ru is accommodated into the hole of the specimen container setting portion, according to claim 1 7. The sample processing apparatus according to any one of 6 above. The sample container setting unit moving unit is configured so that a center position of the hole portion of the sample container setting unit is positioned on a vertical line of the predetermined position where a center position of an area sandwiched between the pair of holding units is positioned. the container holder Before moving sample processing apparatus according to any one of claims 1-7. The container clamping member drive unit is
An annular belt;
A belt drive unit for rotating the annular belt in the forward direction and the reverse direction;
A first connecting portion that connects one container holding member of the pair of container holding members to the annular belt;
A second connecting portion for connecting the other container holding member of the pair of container holding members to the annular belt;
A pulley portion that folds the annular belt,
By arranging the pulley portion so as to fold back the portion of the annular belt between the first connecting portion and the second connecting portion, the belt driving portion rotates the annular belt in the forward direction. In this case, the pair of container clamping members are separated from each other when the pair of container clamping members come close to each other and the belt driving unit rotates the annular belt in the reverse direction. The sample processing apparatus according to claim 1.   The sample processing apparatus according to any one of claims 1 to 9, wherein the container holding member driving unit is configured to bring the pair of container holding members close to each other while moving the pair of container holding members at the same speed. A sample container setting unit having a hole for accommodating the sample container;
A sample aspirating section for inserting a suction tube into the sample container through an opening of the sample container accommodated in the hole of the sample container setting section, and aspirating the sample in the sample container;
Specimen container set for horizontally moving the specimen container setting part between a setting position where the specimen container is set in the hole of the specimen container setting part and an aspiration position where the specimen is aspirated by the specimen aspirating part Moving part,
A pair of container holding members arranged so that a pair of holding parts for holding the sample container accommodated in the hole of the sample container setting part moved to the suction position are opposed to each other;
Both the pair of container clamping members are horizontally moved in a direction perpendicular to the moving direction of the sample container setting unit while maintaining the center position of the region sandwiched between the pair of clamping units at a predetermined position, and are brought close to each other. by, and a container clamping member driving unit for clamping the contained the sample container to the pair of holding portions in the hole of the sample container setting section,
The sample aspirating unit aspirates the sample in the sample container that is accommodated in the hole of the sample container setting unit and is sandwiched between the pair of container sandwiching members at the suction position by the suction tube. , Specimen aspirator.

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