JP5054418B2 - Skin external preparation suitable for cosmetics for cleansing - Google Patents

Description

  The present invention relates to a skin external preparation containing a branched fatty acid ester of a novel polyhydric alcohol useful as a cosmetic raw material.

  Make-up cosmetics are cosmetics that make use of the optical effect of the contained powder to beautifully cover unfavorable skin conditions such as stains. It is a cosmetic that has been challenged to make it stably exist on the skin. In recent years, materials such as core / shell type polymers have been developed that form a firm film on the skin and stably fix the cosmetic film. Improvements in makeup retention, a long-standing issue for makeup cosmetics, have been a major development. However, on the other hand, how to remove the cosmetic film formed on the skin without burden on the skin has become a big problem. In this sense, cleansing cosmetics have come to have a great meaning.

Cleansing cosmetics are cosmetics that remove oily dirt due to the solvent effect of oils, and are typically agents with high internal phase oil-in-water emulsifiers that contain a large amount of nonpolar oils such as hydrocarbons. Although it was in the form, it contains oils with high solvent effect such as 2-ethylhexanoic acid triglyceride, neopentyl glycol di-2-ethylhexanoic acid ester or propylene glycol dicaprylic acid ester, along with the improvement of make-up cosmetics However, the cleansing ability has been improved (see, for example, Patent Document 2, Patent Document 3, Patent Document 4, and Patent Document 5 ), but they are not fully compatible with current makeup cosmetics. Was the current situation. In this regard, it can be said that it has been desired to develop a cosmetic material excellent in the action of removing such makeup cosmetics and to make use of this cosmetic material having excellent cleansing properties.

  On the other hand, the compound represented by the general formula (1) described below is a novel compound not described in any literature, and it is not known at all that such a compound is excellent in the action of removing the makeup cosmetic. This is also the case with 2-ethylhexanoic acid triglyceride, neopentyl glycol di-2-ethylhexanoic acid ester, propylene glycol dicaprylic acid ester, dipropylene glycol diisooctanoate, etc., which are cosmetic materials whose structures are relatively similar. No such effect has been confirmed.

JP 2003-327632 A Japanese Patent Laid-Open No. 08-127512 JP-A-10-87431 Japanese Patent Laid-Open No. 2001-270815 JP 2005-343844 A

  The present invention has been made under such circumstances, and it is an object of the present invention to provide an external preparation for skin that forms a strong cosmetic film and has an excellent effect of removing makeup cosmetics that are excellent in makeup. .

  In view of such a situation, the present inventors have sought for a cosmetic material excellent in the action of forming a strong cosmetic film and removing makeup cosmetics excellent in long-lasting makeup. The branched fatty acid ester of a polyhydric alcohol having a structure represented by the following general formula (1) has such properties, and the skin external preparation containing the same has excellent cleansing properties. It has been found and the invention has been completed. That is, the present invention is as follows.

一般式（１）
（但し、式中Ｒ１、Ｒ２はそれぞれ独立に、水素原子又は分岐脂肪族アシル基を表し、且つ、Ｒ１、Ｒ２の少なくとも一方は分岐脂肪族アシル基であり、ｎ、ｍはそれぞれ独立に０〜４の整数を表し、且つ、ｍはｎと等しいか小さいかである。）

General formula (1)
(In the formula, R 1 and R 2 each independently represent a hydrogen atom or a branched aliphatic acyl group, and at least one of R 1 and R 2 is a branched aliphatic acyl group, and n and m are each independently 0 to 0. Represents an integer of 4 and m is less than or equal to n.)

A cosmetic for cleansing containing a branched fatty acid ester of a polyhydric alcohol, wherein the branched fatty acid ester of the polyhydric alcohol is propylene glycol di-2-ethylhexanoate, propylene glycol mono-2-ethylhexanoate, 1, It is 3-butylene glycol di-2-ethylhexanoate or 1,3-butylene glycol mono-2-ethylhexanoate, and the content of the branched fatty acid ester of the polyhydric alcohol is the total amount of the cosmetic for cleansing. On the other hand, it is 0.1-30 mass%, The said cosmetics for cleansing characterized by the above-mentioned.

  ADVANTAGE OF THE INVENTION According to this invention, the skin external preparation which is excellent in the effect | action which removes the makeup cosmetics which form a strong makeup | decoration film | membrane and is excellent in a long-lasting makeup can be provided.

(1) Branched fatty acid ester of polyhydric alcohol which is an essential component of the skin external preparation of the present invention The skin external preparation of the present invention comprises a branched fatty acid ester of a polyhydric alcohol having a structure represented by the general formula (1). It contains as an essential component. In the general formula (1), R1 and R2 each independently represent a hydrogen atom or a branched aliphatic acyl group, and at least one of R1 and R2 is a branched aliphatic acyl group, and n and m are each independent. Represents an integer of 0 to 4, and m is equal to or smaller than n. As the branched aliphatic acyl group, those having 6 to 20 carbon atoms are particularly preferred, and specifically, 2-ethylbutanoyl group, 2-ethylhexanoyl group, 2-butylhexanoyl group, isopalmitoyl group. , Isostearoyl group, octyldodecanoyl group and the like can be suitably exemplified, and 2-ethylhexanoyl group is particularly preferable. This is because these branched acyl groups not only have a solvent effect suitable for removing the decorative film, but also have an excellent emollient effect. For this reason, the application of the skin external preparation is not limited to cleansing cosmetics, but can be applied to skin external preparations in general, such as skin care cosmetics and skin external preparation bases. Yes.

  In the general formula (1), n and m of the polyhydric alcohol part each independently represent an integer of 0 to 4, m is equal to or smaller than n, and n and m are 0 to 1. The case is particularly preferred. Specifically, as such polyhydric alcohol residue, for example, propylene glycol residue, 1,3-butanediol residue, 1,3-pentanediol residue, 1,4-hexanediol residue and the like are preferable. A propylene glycol residue or 1,3-butanediol residue is more preferable, and a propylene glycol residue is particularly preferable.

Specific examples of such branched fatty acid esters of polyhydric alcohols include propylene glycol di-2-ethylbutanoate, propylene glycol mono-2-ethylbutanoate, propylene glycol di-2-ethylhexanoate, propylene glycol mono-2-ethyl. Hexanoic acid ester, propylene glycol di-2-butyl hexanoic acid ester, propylene glycol mono 2-butyl hexanoic acid ester, propylene glycol diisopalmitic acid ester, propylene glycol monoisopalmitic acid ester, propylene glycol diisostearic acid ester, propylene glycol monoisostearate Acid ester, propylene glycol dioctyldodecanoate, propylene glycol monooctyldodecanoate 1,3-butanediol di-2-ethylbutanoate, 1,3-butanediol mono-2-ethylbutanoate, 1,3-butanediol di-2-ethylhexanoate, 1,3-butanediol mono-2 -Ethylhexanoic acid ester, 1,3-butanediol di-2-butylhexanoic acid ester, 1,3-butanediol mono 2-butylhexanoic acid ester, 1,3-butanediol diisopalmitic acid ester, 1,3- Butanediol monoisopalmitate, 1,3-butanediol diisostearate, 1,3-butanediol monoisostearate, 1,3-butanediol dioctyldodecanoate, 1,3-butanediol monooctyldodecanoate Esters, 1,3-pentanediol 2-ethylbutanoic acid ester, 1,3-pentanediol mono 2-ethylbutanoic acid ester, 1,3-pentanediol di-2-ethylhexanoic acid ester, 1,3-pentanediol mono-2-ethylhexanoic acid ester, 1,3 -Pentanediol di-2-butylhexanoate, 1,3-butanediol mono-2-butylhexanoate, 1,3-pentanediol diisopalmitate, 1,3-pentanediol monoisopalmitate, 1 , 3-pentanediol diisostearic acid ester, 1,3-pentanediol monoisostearic acid ester, 1,3-pentanediol dioctyldodecanoic acid ester, 1,3-pentanediol monooctyldodecanoic acid ester, 1,4-hexanediol diester 2-Eth Rubutanoic acid ester, 1,4-hexanediol mono-2-ethylbutanoic acid ester, 1,4-hexanediol di-2-ethylhexanoic acid ester, 1,3-pentanediol mono-2-ethylhexanoic acid ester, 1,4-hexane Diol di-2-butylhexanoate, 1,4-hexanediol mono-2-butylhexanoate, 1,4-hexanediol diisopalmitate, 1,4-hexanediol monoisopalmitate, 1,4 -Hexanediol diisostearic acid ester, 1,4-hexanediol monoisostearic acid ester, 1,4-hexanediol dioctyldodecanoic acid ester, 1,4-hexanediol monooctyldodecanoic acid ester and the like can be preferably exemplified, and particularly preferably, Professional Examples include lenglycol di-2-ethylhexanoate, propylene glycol mono-2-ethylhexanoate, 1,3-butylene glycol di-2-ethylhexanoate or 1,3-butylene glycol mono-2-ethylhexanoate. Of these, propylene glycol di-2-ethylhexanoate or propylene glycol mono-2-ethylhexanoate is particularly preferable.

  Such a branched fatty acid ester of a polyhydric alcohol is obtained by reacting a branched polyhydric fatty acid with a corresponding polyhydric alcohol and a halogenating agent such as thionyl chloride in the presence of an alkali. It can be produced by reacting a halide. The alkali is preferably added in a large excess with respect to the acyl halide, and examples of such an alkali include pyridine, triethylamine, sodium hydride and the like. If desired, tetrahydrofuran, acetonitrile, dimethylformamide, dimethyl can be used. A solvent such as sulfoxide can also be added for the purpose of assisting in dissolving the substrate or for promoting the precipitation of the salt. The amount of the solvent added is particularly preferably 1 to 20 times the amount of alkali. The addition of acyl halide in such an acylation reaction is preferably carried out under ice cooling, and after completion of the addition, the reaction temperature is gradually raised and maintained at room temperature for 1 to 24 hours. After completion of the reaction, if desired, after filtering off the salt and the like, removing the solvent and excess alkali such as vacuum concentration, washing with water-liquid extraction with ethyl acetate and water, concentrating, and then vacuum distillation or silica gel column It can be obtained by purification by chromatography or the like. The branched fatty acid ester of polyhydric alcohol thus obtained has excellent cosmetic film removal properties. A production example of such a branched fatty acid ester of a polyhydric alcohol is shown below.

<Production Example 1>
7.6 g (0.1 mol) of propylene glycol and 50 g of pyridine were dissolved in 500 ml of tetrahydrofuran. While cooling with ice and stirring, a solution of 35.3 g (0.2 mol) of isooctanoic acid chloride (2-ethylhexanoic acid chloride) in 100 ml of tetrahydrofuran was dropped into this solution over 2 hours. After completion of the dropwise addition, the white precipitate formed was filtered, and tetrahydrofuran and pyridine were removed from the filtrate using a rotary evaporator. The residue was purified by silica gel column chromatography (elution solvent diethyl ether: n-hexane = 3: 7), and the fraction was developed by thin layer chromatography using diethyl ether: n-hexane = 1: 1 as a developing solvent. Sprayed with 50% sulfuric acid aqueous solution at 500 ° C
When the mixture was heated for 10 minutes and colored, the same spot was collected, and two fractions of Rf = 0.78 and Rf = 0.33 were obtained. 18.2 g of the upper (Rf = 0.78) fraction was obtained, and the compound obtained by NMR measurement was confirmed to be propylene glycol diisooctanoate. 5.9 g of the lower part (Rf = 0.33) was obtained, and mass analysis (M + 1: 203) suggested that it was propylene glycol monoisooctanoate.

<Production Example 2>
In the same manner as in Production Example 1, isooctanoic acid chloride was replaced with isostearic acid chloride, and the same operation was performed to obtain 20.1 g of propylene glycol diisostearate and 9.8 g of propylene glycol monoisostearate. The structure was confirmed by thin layer chromatography spots and mass spectrometry (FabMass; M + 1 = 343 and 547).

<Production Example 3>
In the same manner as in Production Example 1, the same operation was carried out by replacing isooctanoic acid chloride with 2-propylpentanoic acid chloride derived from 2-propylpentanoic acid, and 13.5 g of propylene glycol bis (2-propylpentanate). And 5.4 g of propylene glycol mono (2-propylpentanate). The structure was confirmed by thin layer chromatography spots and mass spectrometry (FabMass; M + 1 = 203 and 329).

<Production Example 4>
7.6 g (0.1 mol) of propylene glycol, 5.8 g (0.04 mol) of 2-ethylhexanoic acid and 200 mg of sodium methoxide were mixed, heated at 150 ° C. for 2 hours, and cooled to room temperature. The residue was purified by silica gel column chromatography (elution solvent diethyl ether: n-hexane = 3: 7), and the fraction was developed by thin layer chromatography using diethyl ether: n-hexane = 1: 1 as a developing solvent. When 50% sulfuric acid aqueous solution was sprayed and heated at 500 ° C. for 10 minutes to cause coloration, the same spot was collected, and Rf = 0.78 (propylene glycol 2-ethylhexanoic acid diester; 21 .3 g) and Rf = 0.33 (propylene glycol 2-ethylhexanoic acid monoester; 3.2 g) were obtained.

  Such a branched fatty acid ester of a polyhydric alcohol can contain only one species, or can contain two or more species in combination. Such a branched fatty acid ester of a polyhydric alcohol is preferably contained in an amount of 0.1 to 30% by mass, and preferably 1 to 25% by mass, based on the total amount of the external preparation for skin in the external preparation for skin of the present invention. More preferred. This is because if the amount is too small, the above-described effect may not be achieved, and if the amount is too large, the effect will reach its peak, and there may be cases where the emulsifying system is unfavorably affected.

(2) the external preparation for skin external preparation for skin of the Invention The present invention is characterized by containing a pre-Symbol branched fatty acid ester of a polyhydric alcohol as an essential component. Here, the skin external preparation referred to in the present invention means a general term for those administered for external use on the skin, and specifically, cosmetics including quasi-drugs, pharmaceuticals for external use on skin, miscellaneous items for external use, etc. are preferable. It can be illustrated. Of these, cosmetics are particularly preferable, and cleansing cosmetics are particularly preferable. This is because the excellent properties of the branched fatty acid ester of the essential component polyhydric alcohol can be exhibited without regret. Of course, since the branched fatty acid ester of polyhydric alcohol, which is an essential component, is excellent in solvent properties, it is also preferable to use it as a vehicle for a poorly soluble drug and to apply it to a skin external medicine. Moreover, as a dosage form in such an external preparation for skin, any dosage form widely used in external preparations for skin can be applied without particular limitation, but an especially preferred one is an emulsifier form. Oil emulsifier form. This is because by selecting such a dosage form, water-based soil that is difficult to remove with an oil vehicle can be easily removed.

The external preparation for skin of the present invention can contain, in addition to such components, optional components that are usually used in external preparations for skin. Examples of such optional ingredients include macadamia nut oil, avocado oil, corn oil, olive oil, rapeseed oil, sesame oil, castor oil, safflower oil, cottonseed oil, jojoba oil, coconut oil, palm oil, liquid lanolin, and hardened coconut oil. Oil, wax, liquid paraffin, squalane, pristane, ozokerite, paraffin, ceresin, petrolatum, oil, wax, liquid wax, liquid paraffin, squalane, bean wax, candelilla wax, carnauba wax, ibotarou, lanolin, reduced lanolin, hard lanolin, jojoba wax , Hydrocarbons such as microcrystalline wax, higher fatty acids such as oleic acid, isostearic acid, lauric acid, myristic acid, palmitic acid, stearic acid, behenic acid, undecylenic acid, cetyl alcohol, stearyl alcohol, isostearyl Alcohol, behenyl alcohol, octyldodecanol, higher alcohol such as myristyl alcohol, cetostearyl alcohol, etc., cetyl isooctanoate, isopropyl myristate, hexyldecyl isostearate, diisopropyl adipate, di-2-ethylhexyl sebacate, cetyl lactate, malic acid Diisostearyl, di-2-ethylhexanoic acid ethylene glycol, dicaprate neopentyl glycol, di-2-heptylundecanoic acid glycerin, tri-2-ethylhexanoic acid glycerin, tri-2-ethylhexanoic acid trimethylolpropane, tri Synthetic ester oils such as trimethylolpropane isostearate and pentane erythritol tetra-2-ethylhexanoate, dimethylpolysiloxane, methylphenylpoly Loxane, linear polysiloxane such as diphenylpolysiloxane, cyclic polysiloxane such as octamethylcyclotetrasiloxane, decamethylcyclopentasiloxane, dodecamethylcyclohexanesiloxane, amino-modified polysiloxane, polyether-modified polysiloxane, alkyl-modified polysiloxane, Silicone oils such as fluorine-modified polysiloxane, fatty acid soap (sodium laurate, sodium palmitate, etc.), anionic surfactants such as potassium lauryl sulfate, alkylsulfuric triethanolamine ether, stearyltrimethylammonium chloride, benzalkonium chloride , Cationic surfactants such as laurylamine oxide, imidazoline-based amphoteric surfactants (2-cocoyl-2-imidazolinium hydroxide-1- Carboxyethyloxy disodium salt, etc.), betaine surfactants (alkyl betaine, amide betaine, sulfobetaine, etc.), amphoteric surfactants such as acylmethyl taurine, sorbitan fatty acid esters (sorbitan monostearate, sesquioleic acid) Sorbitan, glycerin fatty acids (glyceryl monostearate, etc.), propylene glycol fatty acid esters (propylene glycol monostearate, etc.), hardened castor oil derivatives, glycerin alkyl ether, POE sorbitan fatty acid esters (POE sorbitan monooleate, Monostearic acid polyoxyethylene sorbitan, etc.), POE sorbite fatty acid esters (POE-sorbite monolaurate, etc.), POE glycerin fatty acid esters (POE-glycerin model) Isostearate, etc.), POE fatty acid esters (polyethylene glycol monooleate, POE distearate, etc.), POE alkyl ethers (POE2-octyldodecyl ether, etc.), POE alkyl phenyl ethers (POE nonylphenyl ether, etc.), pluronic types , POE / POP alkyl ethers (POE / POP2-decyltetradecyl ether, etc.), Tetronics, POE castor oil / hardened castor oil derivatives (POE castor oil, POE hardened castor oil, etc.), sucrose fatty acid ester, alkyl glucoside Nonionic surfactants such as polyethylene glycol, glycerin, 1,3-butylene glycol, erythritol, sorbitol, xylitol, maltitol, propylene glycol, dipropylene glycol Le, diglycerol, isoprene glycol, 1,2-pentanediol, 2,4-hexanediol, 1,2-hexanediol, 1,2 polyhydric alcohols such as octanediol, sodium pyrrolidone carboxylic acid, lactic acid, lactic acid Moisturizing ingredients such as sodium, surface may be treated, powders such as mica, talc, kaolin, synthetic mica, calcium carbonate, magnesium carbonate, anhydrous silicic acid (silica), aluminum oxide, barium sulfate, surface May be treated, bengara, yellow iron oxide, black iron oxide, cobalt oxide, ultramarine, bitumen,
Inorganic pigments of titanium oxide and zinc oxide, surface may be treated, pearl agents such as titanium mica, fish phosphorus foil, bismuth oxychloride, red 202, red 228, which may be raked, Red No. 226, Yellow No. 4, Blue No. 404, Yellow No. 5, Red No. 505, Red No. 230, Red No. 223, Orange No. 201, Red No. 213, Yellow No. 204, Yellow No. 203, Blue No. 1, Green 201 No., purple 201, red 204, etc., organic powders such as polyethylene powder, polymethyl methacrylate, nylon powder, organopolysiloxane elastomer, paraaminobenzoic acid UV absorber, anthranilic acid UV absorption Agent, salicylic acid UV absorber, cinnamic acid UV absorber, benzophenone UV absorber, sugar UV absorber, 2- (2'-hydroxy- UV absorbers such as 5′-t-octylphenyl) benzotriazole and 4-methoxy-4′-t-butyldibenzoylmethane, lower alcohols such as ethanol and isopropanol, vitamin A or its derivatives, vitamin B ₆ hydrochloric acid Salt, vitamin B ₆ tripalmitate, vitamin B ₆ dioctanoate, vitamin B ₂ or a derivative thereof, vitamin B ₁₂ such as vitamin B ₁₂ , vitamin B ₁₅ or a derivative thereof, α-tocopherol, β-tocopherol, γ-tocopherol, vitamin Preferable examples include vitamin E such as E acetate, vitamin D, vitamin H, pantothenic acid, panthetin, pyrroloquinoline quinone, and other antibacterial agents such as phenoxyethanol. The external preparation for skin of the present invention can be produced by treating these optional components and essential components according to a conventional method.

  Among the above-mentioned optional components, particularly preferred are those that can utilize the solvent effect of the branched fatty acid ester of polyhydric alcohol, which is an essential component, that is characteristic of the external preparation for skin of the present invention. For example, sphingosine, ceramide Insoluble components such as triterpenic acids such as oleanolic acid, asiatic acid, ursolic acid, and betulinic acid, glycosides of phytosterol, and fatty acid esters of phytosterol can be particularly preferably exemplified, About 0.5 mass% is preferable, More preferably, it is about 0.02-0.2 mass%.

  Furthermore, since it is excellent also in the powder dispersibility as a solvent, it is also preferable to contain a powder. In particular, it is particularly preferable to contain such a surface-hydrophobized powder because it is excellent in the action of dispersing even a hydrophobized powder, such as hydrogen methyl polysiloxane baking powder, which easily aggregates with a normal oil. The content of the powder is preferably 1 to 30% by mass, more preferably 2 to 25% by mass.

  Hereinafter, the present invention will be described in more detail with reference to examples, but it goes without saying that the present invention is not limited to these examples.

<Example 1>
According to the formulation shown in Table 1 below, a skin external preparation of the present invention, and the emulsified cosmetic and work made. That is, ingredients (a) and (b) were weighed, heated and dissolved at 80 ° C., and (b) was gradually added to a under stirring. After completion of the addition, the mixture was stirred until uniform, and then stirred and cooled to obtain an emulsified cosmetic 1. In the same manner, Comparative Example 1 in which propylene glycol diisooctanoate was substituted with dipropylene glycol diisooctanoate, Comparative Example 2 in which neopentyl glycol di-2-ethylhexanoate was substituted, and propylene glycol dicaprylate comparative example was replaced 3 was also made work. As a control example, propylene glycol diisooctanoate substituted with squalane was similarly prepared and used.

<Test Example 1>
The emulsified cosmetic 1 and Comparative Examples 1 to 3 and the control example were subjected to a storage test for 6 months at −10 ° C., and the temperature was returned to 20 ° C., followed by microscopic observation. Although no precipitation of crystals was observed, precipitation of crystals was observed in Comparative Examples 1 to 3 and the control example. It was shown that the solvent effect of the external preparation for skin of the present invention is high.

<Example 2>
According to the formulations shown in Table 2 below, a skin external preparation of the present invention, and the cleansing cosmetic composition 2 of an oil-in-water and work made. That is, it was confirmed that the prescription ingredients were heated and stirred at 70 ° C. to form a single phase, and stirred and cooled to obtain cleansing cosmetic 2 in which water was solubilized. In the same manner, Comparative Example 4 in which propylene glycol diisooctanoate was substituted with dipropylene glycol diisooctanoate, Comparative Example 5 in which neopentyl glycol di-2-ethylhexanoate was substituted, and propylene glycol dicaprylate A substituted comparative example 6 was also produced. As a control example, propylene glycol diisooctanoate substituted with squalane was similarly prepared and used.

<Test Example 1>
The cleansing effect was investigated about the cleansing cosmetic 2, the comparative examples 4-6, and the control example which are the said skin external preparations of this invention. That is, a line of 4 cm × 2 cm is drawn on the inner side of the forearm with an eye liner (corresponding to a cosmetic that forms a strong decorative film) shown in Table 3 below. CR400 "), and then the sample was lightly rubbed three times with cut cotton impregnated with the specimen, washed again with water and measured again to examine the color difference. The results are shown in Table 4. This shows that cleansing cosmetic 2 which is an external preparation for skin of the present invention has an excellent makeup removing action.

<Reference Example 3>
As in Example 2, according to the formulations shown in Table 5 below, a peel Hadagaiyo agent, to prepare a cleansing cosmetic composition 3 water solubilizing type. Comparative Example 7 in which propylene glycol diisooctanoate was replaced with dipropylene glycol diisooctanoate, Comparative Example 8 in which neopentyl glycol di2-ethylhexanoate was substituted, and Comparative Example 9 in which propylene glycol dicaprylate was substituted Produced. The results of evaluation according to Test Example 1 are shown in Table 6.

<Example 4>
According to the formulation shown in Table 7 below, a skin external preparation of the present invention was created made an emulsion 4. That is, each of the components (a), (b), and (c) was heated to 80 ° C., and (b) was gradually added to emulsify with stirring, followed by neutralization by addition of (c) and stirring and cooling to obtain an emulsion 4. . This was subjected to a storage test for 6 months at −10 ° C., and the temperature was returned to 20 ° C., followed by microscopic observation. No crystal precipitation was observed, and the solvent effect of the external preparation for skin of the present invention was confirmed. It was.

<Example 5>
According to the formulation shown in Table 8 below, an ultraviolet protective cosmetic that is an external preparation for skin of the present invention was prepared. That is, the components (a) and (b) are heated and solubilized at 80 ° C., the component (c) is added to the component (a) and dispersed well, and then the components (b) are gradually added and emulsified with stirring. An ultraviolet protective cosmetic in the form of a water-in-water emulsifier was obtained. In the same manner, Comparative Example 10 in which propylene glycol diisooctanoate was replaced with dipropylene glycol diisooctanoate was also prepared, and when SPF was measured by the SPF measurement method defined by the Japan Cosmetic Industry Association, The UV protective cosmetic of the present invention had an SPF value of 21, while that of Comparative Example 10 was 18. This seems to be because the dispersibility of titanium dioxide and zinc oxide is improved by the solvent effect of propylene glycol diisooctanoate.

<Example 6>
The same operation as in Example 5 was performed, and an oil-in-water emulsifier type foundation was obtained according to the formulation shown in Table 9 below. Operating in an analogous way comparative example was replaced with propylene glycol di isooctanoate sulfonate dipropylene glycol di isooctanoate sulfonate 11 was also made work. Regarding the foundation of the oil-in-water emulsifier type, which is an external preparation for skin of the present invention, and Comparative Example 11, the uniformity and beauty of the finish were compared, and the foundation of the oil-in-water emulsifier type of the present invention was remarkably superior. . This seems to be due to the good dispersibility of the powder.

<Example 7>
According to the formulation shown in Table 10 below, a powder foundation, which is a skin external preparation of the present invention, was prepared. That is, after mixing the ingredients of A with a Henschel mixer, pulverizing with a palverizer equipped with a 1 mm herringbone screen, returning to the Henschel mixer, spraying the ingredients of B while mixing, coating this, 2 mm herring It was pulverized with a pulverizer equipped with a bone screen, filled in a metal pan, and pressure-molded to obtain a powder foundation that is an external preparation for skin of the present invention. In the same manner, Comparative Example 12 in which propylene glycol diisooctanoate was replaced with dipropylene glycol diisooctanoate was also produced. In the pressure molding, when 100 prototypes were made, 100 powder foundations, which are external preparations of the present invention, were all normal products, but in Comparative Example 12, there were 3 defective products due to uneven color. It has been proved that the external preparation for skin of the present invention has very good dispersibility of the colorant due to the solvent effect and color unevenness hardly occurs during the production process.

<Reference Example 8>
In the same manner as in Example 1, emulsified cosmetics 2, 7, and 8, which are external preparations for skin of the present invention, and emulsified cosmetics 3 to 6 as reference examples were prepared and tested according to the formulations shown in Table 11 below. The cleansing effect was examined in the same manner as in Example 1. The results are shown in Table 12. It turns out that the same effect is show | played also by the branched fatty acid ester of another polyhydric alcohol.

The present invention can be applied to an external preparation for skin such as cosmetics.

Claims (1)

A cosmetic for cleansing containing a branched fatty acid ester of a polyhydric alcohol, wherein the branched fatty acid ester of the polyhydric alcohol is propylene glycol di-2-ethylhexanoate, propylene glycol mono-2-ethylhexanoate, 1, It is 3-butylene glycol di-2-ethylhexanoate or 1,3-butylene glycol mono-2-ethylhexanoate, and the content of the branched fatty acid ester of the polyhydric alcohol is the total amount of the cosmetic for cleansing. On the other hand, it is 0.1-30 mass%, The said cosmetics for cleansing characterized by the above-mentioned .