JP4658745B2 - Toothpaste composition - Google Patents

Description

  The present invention relates to a dentifrice composition containing erythritol.

  In general, the purpose of brushing teeth is to clean the mouth and obtain a refreshing feeling. A fragrance ingredient represented by menthol, which is usually included in a toothpaste composition, is indispensable for imparting a refreshing feeling, but in recent years, there has been a tendency to increase the number of oily meals and meals using spices. Therefore, a toothpaste composition having a higher refreshing feeling is desired.

  As a means to improve the refreshing feeling, there are methods such as increasing the blending amount of perfume ingredients or adding a solvent component such as ethanol. However, increasing the blending amount of these ingredients increases the irritation in the oral cavity. Moreover, since foaming is suppressed, there arises a problem that the feeling of use when polished is impaired.

  Therefore, a toothpaste composition that obtains a higher refreshing feeling without increasing the blending amount of a fragrance component or a solvent such as ethanol is desired.

Patent Document 1 discloses a toothpaste composition having an excellent refreshing feeling, which contains a component that causes an endothermic hydration reaction such as erythritol and has a water content of 10% by mass or less. However, because the water content is low, the water-soluble polymer compounded as a binder does not dissolve sufficiently, and over time, moisture and other liquid components can be seen to bleed out of the system. There was a problem with sex. Moreover, although a cool feeling was obtained, it did not reach a clear cool feeling in the oral cavity.
JP 2000-191383 A

  An object of the present invention is to provide a toothpaste composition containing erythritol, which has a higher refreshing sensation and cooling sensation and is excellent in long-term storage stability.

  The present inventor first studied a method for enhancing the refreshing feeling and cooling feeling when brushing teeth, and as a result, contains erythritol having a specific particle size, and further adjusts its content and the amount of water in the composition. And it discovered that a refreshing feeling and a cool feeling could be improved. However, since the amount of water in the composition is limited, the separation phenomenon of water and other liquid components occurs, and the storage stability is not sufficient. Thus, as a result of examining methods for improving storage stability, it was found that the addition of specific oil-absorbing silica instead of silica used as an abrasive is effective for storage stability.

That is, the present invention includes the following components (A) to (C):
(A) Erythritol having a particle diameter of less than 355 μm 20 to 60% by mass
(B) Water 10-40% by mass
(C) Silica with an oil absorption measured according to JIS K5101 of 200 to 400 ml / 100 g 0.5 to 10% by mass
A toothpaste composition containing
The present invention also includes the following components (A) to (C):
(A) Erythritol having a particle diameter of less than 355 μm, 25 to 60% by mass
(B) Water 10-40% by mass
(C) Silica with an oil absorption measured according to JIS K5101 of 200 to 400 ml / 100 g 0.5 to 10% by mass
Is a toothpaste composition.

  According to the present invention, it is possible to provide a toothpaste composition that has a high refreshing feeling and a cool feeling and is also excellent in long-term storage stability.

The dentifrice composition of the present invention is characterized by containing erythritol (component (A)) having a particle size of less than 355 μm. Normally available erythritol is crystalline erythritol obtained by recrystallizing after fermenting glucose, and its particle size is larger than that of the product of the present invention. Therefore, it is preferable to use what obtained the erythritol grind | pulverized and adjusted the particle diameter for the toothbrushing composition of this invention.
A roller mill, hammer mill, high-speed pulverizer, pulverizer, etc. are generally used to pulverize erythritol, but a high-speed pulverizer and hammer mill that are easy to adjust the particle size and excellent in production efficiency. Is preferred.
The structure of erythritol includes three isomers of L-erythritol, D-erythritol, and meso-erythritol, and the present invention may have any of these structures. As crystalline erythritol, commercially available products such as those manufactured by Nikken Chemical Co., Ltd., Mitsubishi Chemical Foods Co., Ltd., and Celestor are available.

  The particle diameter of erythritol is less than 355 μm because it can provide a cool feeling and a cool feeling, but is preferably 3 μm or more and less than 355 μm. From the viewpoint that the cooling sensation persists in the mouth, it is preferably 45 μm or more and less than 355 μm, more preferably 45 μm or more and less than 300 μm, and particularly preferably 45 μm or more and less than 250 μm.

The erythritol particle size is measured as follows.
Sieve: JIS standard sieve φ75mm
Opening: From the upper stage, a receiver is provided under a sieve having openings of 500 μm, 355 μm, 250 μm, 180 μm, 125 μm, 90 μm and 45 μm, respectively.
Shaker: Micro type electromagnetic vibrator M-2 type (Tsutsui Rikenki Co., Ltd.)
Method: Place 15 g of sample on 500 μm sieve and classify with electromagnetic vibrator for 5 minutes. The total amount of erythritol present on a sieve having openings of 250 μm, 180 μm, 125 μm, 90 μm and 45 μm is defined as erythritol having a particle size of 45 μm or more and less than 355 μm.
The particle size distribution of less than 45 μm can be measured with a dry laser distribution diffraction particle size distribution measuring apparatus.

In the toothpaste composition of the present invention, the content of erythritol having a particle size of less than 355 μm is 20 to 60% by mass, more preferably 25 to 55% by mass, and even more preferably 30 to 50% from the viewpoint of obtaining a high refreshing feeling. % By mass.
For this reason, the compounding quantity of the erythritol whose particle diameter is less than 355 micrometers is 25-60 mass%, More preferably, it is 30-55 mass%, More preferably, it is 35-50 mass%.

  In the toothpaste composition of the present invention, the content of water (component (B)) is 10 to 40% by mass, more preferably 12 to 35% by mass, from the viewpoint of obtaining storage stability and higher refreshing feeling and cooling feeling. More preferably, it is 15-30 mass%, Most preferably, it is 18-25 mass%.

The silica (component (C)) used in the present invention has an oil absorption of 200 to 400 ml / 100 g, more preferably 220 to 380 ml / 100 g, and still more preferably 250 to 350 ml / from the viewpoint of improving stability. 100 g. Here, the amount of oil absorption indicates the amount of oil that can be supported by silica, and the measurement method conforms to JIS K5101. Such silica is available from Silicia, Silopure (Fuji Silysia Chemical), Thixosyl (Rhodia), Sorbosil (Ineos Silica), Fine Seal (Tokuyama), Nipgel (Tosoh Silica) It is. Note that silica having a large amount of oil absorption used here is different from silica used as an abrasive.

  In the toothpaste composition of the present invention, the content of silica is 0.5 to 10% by mass, more preferably 1 to 8% by mass, further preferably 1.2 to 7% by mass, particularly from the viewpoint of storage stability. Preferably it is 1.5-5 mass%.

  Furthermore, the dentifrice composition of the present invention can contain a binder. In the toothpaste composition, the content of the binder is preferably 0.6 to 2% by mass, more preferably 0.7 to 1.5% by mass, and still more preferably 0.8 to 1%, from the viewpoint of storage stability. .2% by mass. Binders include sodium alginate, sodium carboxymethylcellulose, carrageenan, xanthan gum, sodium polyacrylate, hydroxyethylcellulose, hydroxypropylcellulose, pectin, tragacanth gum, gum arabic, guar gum, karaya gum, locust bean gum, gellan gum, tamarind gum, psyllium It is preferable to use one or more water-soluble polymers composed of seed gum, polyvinyl alcohol, sodium chondroitin sulfate, and methoxyethylene maleic anhydride copolymer.

  In the toothpaste composition of the present invention, in addition to the above components, for example, foaming agent, foaming aid, abrasive, wetting agent, sweetener, preservative, enzyme, pH adjuster, bactericidal agent, medicinal component, pigment, dye, A fragrance | flavor etc. can be contained suitably. Moreover, you may contain erythritol (355 micrometers or more) of another particle diameter. Even in this case, the average particle diameter of all erythritol particles contained in the composition or the average particle diameter of all erythritol particles to be blended is preferably 200 μm or less, more preferably 30 to 150 μm. When the average particle size is 45 μm or more, the sieving rate (cumulative amount) is plotted on a regular established paper and a value corresponding to 50% is adopted. When the average particle size is less than 45 μm, a dry laser distribution diffraction type particle size distribution measuring device is used. The value measured by is adopted.

  As abrasives, silica-based abrasives such as precipitated silica, silica gel, aluminosilicate, zirconosilicate, dicalcium phosphate dihydrate and anhydrous, calcium pyrophosphate, calcium carbonate, alumina, aluminum hydroxide, acetic acid Magnesium, tribasic magnesium phosphate, zeolite, synthetic resin-based abrasive and the like are preferably used.

  As the wetting agent, glycerin, sorbitol, propylene glycol, polyethylene glycol, xylitol, maltite, lactit, trehalose and the like are preferably used.

  Furthermore, examples of the sweetening agent include saccharin sodium, aspartame, thaumatin, acesulfame potassium, stevioside, stevia extract, paramethoxycinnamic aldehyde, neohesperidyl dihydrochalcone, and perilartin.

  As a fragrance, 1-menthol, carvone, anethole, eugenol, limonene, peppermint oil, spearmint oil, ocimen, n-amyl alcohol, citronellol, α-terpineol, methyl salicylate, methyl acetate, citronole acetate, cineol, linalool, Examples include ethyl linalool, crocodile, thymol, lemon oil, orange oil, sage oil, rosemary oil, cinnamon oil, pimento oil, perilla oil, clove oil, and eucalyptus oil.

  Other various active ingredients include water-soluble phosphate compounds such as potassium phosphate and sodium salt of orthophosphoric acid, allantochlorohydroxyaluminum, hinokitiol, lysozyme chloride, glycyrrhizic acid and its salts, sodium chloride, tranexamic acid, epsilon. Aminocaproic acid, dl-tocopherol acetate, azulene, glycyrrhetinic acid, copper chlorophyllin sodium, copper compounds such as copper gluconate, aluminum lactate, strontium chloride, potassium nitrate, berberine, hydroxamic acid and its derivatives, sodium tripolyphosphate, zeolite, dextranase , Mutanase, amylase, methoxyethylene, maleic anhydride copolymer, polyvinylpyrrolidone, epidihydrocholesterin, dihydrocholesterol, zinc citrate, Float, cork tree bark, clove, rosemary, scutellaria, an extract of such safflower, alpha-bisabolol, chlorhexidine salts, triclosan, cetylpyridinium chloride, benzethonium chloride, trichlorocarbanilide, and the like.

  In the toothpaste composition of the present invention, it is desirable that erythritol is dispersed in a powder state from the viewpoint of obtaining a higher refreshing feeling. For this purpose, erythritol is preferably added as a powder to the final production process. By using such a production method, erythritol can be present in a powder state in the toothpaste composition without being substantially dissolved in water. Specifically, for example, after measuring the prescribed amount of each component such as purified water, wetting agent, binder, flavoring agent, preservative, abrasive, foaming agent, sweetener, and medicinal component, it is according to certain production conditions. The toothpaste composition of the present invention can be produced by mixing and fully swelling the binder, and further adding a polishing agent, a foaming agent, a flavoring agent, and powdered erythritol and defoaming and mixing.

[Preparation of toothpaste composition]
According to the composition shown in Table 1, toothpaste compositions of Examples 1-4 and Comparative Examples 1-3 were prepared.
Erythritol was added last.

(1) Evaluation of cool feeling and cool feeling Ten subjects (5 men, 5 women) took 1 g of each brushing composition on a toothbrush and brushed freely for about 2 minutes. The strength of the refreshing feeling after rinsing was evaluated according to the following criteria. In addition, the result of the determination shown in Table 1 shows the highest evaluation among 10 people.
<Evaluation criteria for coolness>
◎: Strong feeling in mouth ○: Refreshing feeling in mouth is slightly strong ×: Feeling in mouth is weak <Evaluation criteria for cool feeling>
◎: The mouth feels clear and the cool feeling persists. ○: The mouth feels a little cool. ×: The mouth feels cool.

(2) Evaluation of storage stability Each toothpaste composition shown in Table 1 was packed in a toothpaste tube for storage, and stored at 5 ° C, room temperature, and 40 ° C for 3 months. Thereafter, the tube was opened and whether or not the liquid component was separated from the toothpaste composition was evaluated according to the following criteria.
<Evaluation criteria for storage stability>
◎: No liquid separation is observed ○: Liquid separation is slightly observed ×: Liquid separation is clearly observed

(* 1): Erythritol having a particle size distribution of 3% to less than 45 μm, 12% by mass, 45 μm to less than 250 μm, 82% by mass, 250 μm to less than 300 μm, 5% by mass, average particle size of 77 μm
(* 2): Erythritol having a particle size of less than 355 μm, 6% by mass, 355 μm or more but less than 1400 μm, 94% by mass, average particle size of 468 μm
(* 3): oil absorption of 300 ml / 100 g silica
(* 4): oil absorption of 120ml / 100 g silica

As shown in Table 1, the toothpaste compositions of Examples 1 to 4 contain a large amount of erythritol having a particle size of less than 355 μm, and further contain silica having an oil absorption of 300 ml / 100 g. The result was excellent coolness and long-term storage stability. Furthermore, since the toothpaste compositions of Examples 2 to 4 contained more erythritol having a particle size of less than 355 μm, the refreshing feeling and cooling feeling were further improved.

On the other hand, in the toothpaste composition of Comparative Example 1, the content of erythritol having a particle size of less than 355 μm was small, and the amount of water in the composition was large, so that the refreshing feeling and cooling feeling were weak. In addition, the toothpaste composition of Comparative Example 2 did not contain silica having an oil absorption of 300 ml / 100 g, and thus the long-term storage stability was poor. In addition, the toothpaste of Comparative Example 3 contains a large amount of erythritol having a particle size of 355 μm or more, so the cooling feeling is weak, and furthermore, it does not contain silica with an oil absorption of 300 ml / 100 g, so it has long-term storage stability. The result was bad.

Claims (3)

The following components (A) to (C):
(A) Erythritol having a particle diameter of less than 355 μm 20 to 60% by mass
(B) water from 12 to 40 wt%
(C) Silica having an oil absorption measured according to JIS K5101 of 200 to 400 ml / 100 g 0.5 to 10% by mass
A toothpaste composition comprising erythritol dispersed in powder form in the composition. The following components (A) to (C):
(A) Erythritol having a particle diameter of less than 355 μm, 25 to 60% by mass
(B) water from 12 to 40 wt%
(C) Silica having an oil absorption measured according to JIS K5101 of 200 to 400 ml / 100 g 0.5 to 10% by mass
A toothpaste composition in which erythritol is dispersed in a powder state in the composition.   Furthermore, the dentifrice composition of Claim 1 or 2 containing 0.6-2 mass% of binders.