JP4249338B2 - Dissolving device and method of using the same - Google Patents

Description

[0001]
BACKGROUND OF THE INVENTION
The present invention relates to a dissolution apparatus for dissolving a powder drug for dialysis, which becomes a dialysis stock solution used for hemodialysis when dissolved in water, to a predetermined concentration.
[0002]
[Prior art]
Dialysis fluids used for the treatment of patients with renal failure in hospitals are generally divided into bicarbonate and acetic acid. Of these, bicarbonate-based dialysate does not contain sodium bicarbonate (hereinafter referred to as “bicarbonate”). It is prepared by mixing water with two types of drugs, called A agent and sodium bicarbonate (hereinafter referred to as B agent).
[0003]
In recent years, from the viewpoint of improving transportability, attempts have been made to dissolve these A and B agents in powder form (hereinafter referred to as dialysis powder) in hospitals that perform dialysis treatment. The concentration of the solution (especially B agent) tends to decrease with time, and it was difficult to prepare the next day after dialysis. That is, for example, sodium bicarbonate (NaHCO ₃ ) in the B agent reacts during storage and decomposes into Na ₂ CO ₃ , CO ₂ , and H ₂ O, so that the concentration is likely to decrease.
[0004]
For this reason, dissolution work is required for each dialysis, and various types of dissolution apparatuses for dissolution have been proposed. For example, Japanese Patent Application Laid-Open No. 57-159529 discloses a dissolution apparatus in which two dissolution tanks having substantially the same capacity are provided, and a dialysis stock solution produced by stirring in each tank is fed to an artificial dialysate supply apparatus. Yes.
With such a configuration, periodic cleaning can be performed alternately, so that the dialysis stock solution can be continuously supplied from the other dissolution tank even when one dissolution tank is cleaned, and it is hygienic. Moreover, it is possible to deal with a sudden trouble of one melting apparatus with only the other melting apparatus.
[0005]
[Problems to be solved by the invention]
However, in the above-described conventional dissolution apparatus, each of the two dissolution tanks provided side by side must be provided with detection means for detecting the liquid level of the dialysis stock solution, which increases manufacturing costs and increases maintenance work. There was a problem of doing.
[0006]
The present invention has been made in view of such circumstances, and by obtaining a dialysis stock solution having a desired concentration only by detecting the volume of one of the dialysis stock solutions of the two dissolution tanks provided side by side, It is an object of the present invention to provide a melting apparatus that can reduce manufacturing costs and reduce maintenance work.
[0007]
[Means for Solving the Problems]
The invention according to claim 1 is a dissolution apparatus for dissolving a powder drug for dialysis to obtain a dialysis stock solution, a main tank having a liquid level detecting means for detecting a liquid level of the stored dialysis stock solution, and the dialysis A sub-tank containing powder medicine and having a smaller capacity than the main tank; a water supply line for supplying water for dissolving the dialysis powder medicine into the sub-tank; an opening formed in a side wall of the main tank; The subtank is connected to an opening formed on the side wall of the sub tank, and the dialysis stock solution overflows into the main tank when the liquid level of the dialysis stock solution reaches the opening in the sub tank. A connection line for flowing the stock solution for dialysis that exceeds a predetermined liquid level into the main tank, and a known level converted from the predetermined liquid level of the sub tank Calculating means for calculating the total volume of the dissolved dialysis solution from the product and the volume calculated from the liquid level detected by the liquid level detecting means; and the dialysis solution in the main tank or sub tank A dialysis solution supply device and a communication line that connects the main tank and the water supply line, and the dialysis stock solution that has flowed into the main tank from the sub tank via the connection line. The dialysis undiluted solution can be circulated between the main tank and the sub tank by supplying the sub tank again through the communication line and the water supply line.
[0008]
According to such a configuration, after supplying the dialysis powder medicine stored in the subtank in the water supply line and flowing out the dialysis stock solution exceeding the predetermined liquid level of the subtank to the main tank side through the connection line, The volume of the dialysis stock solution in the main tank is detected from the liquid level detected by the detecting means. The total volume of the prepared dialysis stock solution is obtained by the computing means performing the computation of the volume obtained by the liquid level detecting means and the computing means and the volume converted from the predetermined liquid level in the sub tank. The prepared dialysis solution is sent from the main tank or the sub tank to the dialysate supply device through the supply line.
[0009]
According to the second aspect of the present invention, the liquid level of the dialysis undiluted solution that has been dissolved in the dialysis powder drug previously introduced into the sub-tank with water from the water supply line and has flowed into the main tank through the connection line. Is detected by the liquid level detecting means, the volume of the dialysis stock solution is calculated by calculating means based on the detection result, and the dialysis stock solution is controlled by controlling the water supply line so as to obtain a predetermined concentration. A dialysis stock solution preparation step, and after the dialysis stock solution preparation step, a dialysis stock solution supply step of feeding the dialysis stock solution from the main tank or sub tank to the dialysate supply device via the supply line, During the dialysis undiluted solution supply step, the subtank is washed or disinfected while the dialysis undiluted solution is fed from the main tank to the dialysate supply device, and after the washing step, the subtank It characterized by having a a dialysis powder medicine input step of inputting the dialysis powder medicament for next dialysis.
[0010]
According to a third aspect of the present invention, when the dialysis stock solution obtained by the dialysis stock solution preparation step is less than a necessary amount, the dialysis stock solution is supplied from the sub tank to the dialysate supply device instead of the dialysis stock solution supply step. An additional dissolution step of additionally dissolving the dialysis stock solution in the main tank is performed.
[0011]
DETAILED DESCRIPTION OF THE INVENTION
Hereinafter, embodiments of the present invention will be specifically described with reference to the drawings.
The dissolution apparatus according to the present embodiment dissolves a powder drug for dialysis to obtain a dialysis stock solution. As shown in FIG. 1, a main tank 1, a sub tank 2, a liquid level detection means 3, and a shower 4 are used. 5, a connection line 6, a disinfection unit 7, a concentration cell 8, a calculation means 9, a water supply means 10, a chamber 12, a plurality of valves V1 to V8, a line connecting these valves, and a filter F1. The main component is a pump P.
[0012]
The main tank 1 is a tank having a relatively large capacity compared to the sub tank 2, and has a liquid level detecting means 3 for detecting the liquid level of the stored dialysis stock solution. The liquid level detection means 3 may be either a contact type or a non-contact type with respect to the stock solution for dialysis accommodated, and is constituted by a liquid level sensor by floating, an ultrasonic sensor, a magnetostrictive linear displacement sensor, or the like. .
[0013]
When the liquid level is detected by the liquid level detecting means 3, the detected value is transmitted to the calculating means 9 as an electric signal. When a signal is sent to the calculation means 9, a calculation for converting the level of the dialysis stock solution to the volume of the dialysis stock solution is performed, and the volume of the dialysis stock solution stored in the main tank 1 is recognized.
[0014]
A shower 4 for cleaning the inside of the main tank 1 is attached to the upper part of the inner wall of the main tank 1 and is connected to the water supply means 10 via lines L1 to L5. Among these, a valve V1 is interposed in the line L2, and a pump P is interposed in the line L3. When the valve V1 is opened while driving the pump P, water can be sprinkled from the shower 4 into the main tank 1.
[0015]
A line L6 extends from the opening 1a at the bottom corner of the main tank 1, and a line L8 extends from the opening 1b at the center of the bottom of the main tank 1. The line L6 is L3 and the line L8 is L12. And L11 are connected to each other.
[0016]
Furthermore, the opening 1a is covered with the filter F1, and when the pump P is driven, the dialysis stock solution filtered by the filter F1 passes through the lines L6, L3, L4, L12, and L8 from the opening 1b to the main tank 1. Returned to By such circulation, the dialysis stock solution in the main tank 1 can be stirred, and a dialysis stock solution having a uniform concentration can be obtained.
[0017]
A line L10 extends from the opening 1c on the side wall of the main tank 1, and the line L10 is connected to the intersection of the line L12 and the line L8 via the line 11. A concentration cell 8 is provided in the line L11, and the concentration of the dialysis stock solution passing through the line L11 can be measured.
Note that a disinfection unit 7 is disposed on the upper part of the main tank 1, and the main tank 1 or the inside of the line can be disinfected with the disinfecting liquid supplied from the disinfection unit 7.
[0018]
The sub-tank 2 is a tank having a relatively small capacity compared to the main tank 1, and is provided along with the main tank 1 and can accommodate a predetermined amount of powder drug for dialysis.
A line L13 extends from the opening 2a at the center of the bottom surface of the sub tank 1, and the line L13 is connected to the water supply means 10 via the lines L14, L4, L3, L2, and L1. The line L14 is provided with a valve V2. When the valve V2 and the valve V1 are opened and the pump P is driven, water can be supplied into the sub tank 2. The lines formed by the lines L1, L2, L3, L4, L14, and L13 form a water supply line for supplying water for dissolving the dialysis powder drug to the sub tank 2.
[0019]
A shower 5 similar to the shower 4 is formed in the upper portion of the sub tank 2 and is connected to the water supply means 10 via a line L16. The line L16 is provided with a valve V7, which is opened when the sub tank 2 is cleaned, and is closed at other times.
[0020]
A line 15 extending from the intersection of the lines L13 and L14 and connected to the chamber 12 and a line L16 extending from the intersection of the lines L3 and L4 and connected to the chamber 12 are formed. A line L17 connected to the dialysate supply device 11 for supplying dialysate to the patient and a line L18 connected to the opening 1d formed on the side wall of the main tank 1 are extended.
[0021]
The lines L13, L15, and L17, or the lines L6, L3, L16, and L17 form a supply line for feeding the dialysis stock solution in the main tank 1 or the sub tank 2 to the dialysis supply device 11.
[0022]
On the other hand, a line L12 connecting the intersection of the lines L11 and L8 and the intersection of the lines L4 and L5 is formed, and a line L9 extending from the intersection of the lines L13 and L15 to the drain outlet is formed, and the line L12 is arranged. By opening the valve V6 and the valves V2 and V5, the dialysis stock solution in the main tank 1 can be drained. Thus, the lines L13 and L9 or the lines L8, L12, L14, and L9 form a drainage line that discharges the liquid in the main tank 1 or the sub tank 2. A line L7 is formed as a separate drainage line.
[0023]
The connecting line 6 feeds a dialysis stock solution exceeding a predetermined liquid level in the sub tank 2 to the main tank 1, and has an opening 1 e formed in the upper side wall of the main tank 1 and an upper side wall of the sub tank 2. The formed opening 2b is connected. That is, the dialysis stock solution rising due to the water supply into the sub tank 2 overflows when it reaches the opening 2 b and flows into the main tank 1 through the connection line 6. Here, since the formation position of the opening 2b is determined, the predetermined liquid level is the position where the opening 2b is formed, and the volume converted from the predetermined liquid level is known.
[0024]
The calculation means calculates the total volume of the dissolved dialysis stock solution from the volume converted from the predetermined liquid level in the sub tank 2 and the liquid level detected by the liquid level detection means 3. Etc.). In principle, since the volume of the dialysis stock solution in the sub-tank 2 is known, the sum of the volume of the dialysis stock solution in the main tank 1 is the total volume of the dialysis stock solution. Therefore, the total volume of the dialysis raw material is preferably obtained by adding a predetermined value to the added value.
[0025]
Next, the effect | action which concerns on the melting apparatus of the said structure is demonstrated.
After completion of dialysis on the 1st day, a powder drug for dialysis necessary for the next day is charged in the sub tank 2 in advance (dialysis powder drug charging step). Before starting dialysis on the next day, in order to dissolve the powder for dialysis in the sub-tank 2 introduced on the previous day, the valves P1 and V2 are opened to open the water supply line, and the pump P is driven. Then, water is supplied from the water supply means 10 into the sub tank 2 by the action of the pump P. Unless otherwise noted, each valve is not opened and remains closed.
[0026]
In the sub-tank 2, the dialysis powder drug is stirred by supplying water to prepare a dialysis stock solution. When the level of the dialysis stock solution rises and reaches the opening 2b, the dialysis stock solution overflows, and the connecting line 6 Into the main tank 1.
The dialysis stock solution that has flowed into the main tank 1 flows into the water supply line through the line L6, and is again supplied into the sub tank 2 together with water from the water supply means. Thus, the dialysis stock solution circulates between the main tank 1 and the sub tank 2 and gradually becomes a dialysis stock solution having a uniform concentration.
[0027]
At this time, if the valve V6 is opened, a part of the dialysis stock solution to be circulated returns to the main tank 1 from the line L8 by the action of the pump P, and is stirred. Thus, since the dialysis stock solution returning to the main tank 1 and the sub-tank 2 is blown upward from the center of the lower surface of each tank, the concentrated dialysis stock solution that tends to accumulate on the bottom surface of the tank is agitated. The concentration of the stock solution for dialysis is made more uniform.
[0028]
A part of the dialysis stock solution passing through the line L12 is diverted to the line L11 and returned to the main tank 1 from the side wall of the main tank 1 through the line L10. Concentration measurement is performed in the concentration cell 8 while the dialysis undiluted solution passes through this line, and if the concentration is abnormal, a warning is displayed to the operator by stopping the apparatus or using an operation panel (not shown). However, in this embodiment, since the concentration measurement of the dialysis stock solution is sufficient to detect the volume of the prepared dialysis stock solution, the concentration measurement by the concentration cell 8 is appropriately performed and the concentration measurement is not performed. Also good.
[0029]
When a predetermined amount of the dialysis stock solution is accumulated in the main tank 1, the valve V1 is closed, the water supply line is shut off and the pump P is stopped, and the dialysis stock solution flows from the connection line 6 into the main tank 1. When the operation stops, the liquid level detection means 3 detects the liquid level of the dialysis stock solution in the main tank 1.
[0030]
The volume of the whole dialysis stock solution in the main tank 1 and the sub tank 2 is calculated by the calculating means 9 from the detected value of the liquid level, and the volume of the whole dialysis stock solution becomes a predetermined concentration with respect to the charged dialysis drug. Then, the valve V1 is opened again until it reaches, and the dialysis undiluted solution preparation step is completed by performing circulation and stirring for a while. Thus, the reason for dividing the water supply into two is that the entire volume changes when the powder drug for dialysis dissolves in water. That is, since the dialysis powder drug dissolves in water and the volume decreases, the volume of the dialysis stock solution decreases from the volume obtained by adding the dialysis powder drug and the amount of water supply.
[0031]
In addition, since the amount of volume reduction varies depending on the dialysis powder drug to be dissolved, it is difficult to perform water supply in anticipation of the volume reduction amount in advance. Therefore, 80 to 90% of the target water is supplied first, and after the powder drug for dialysis is completely dissolved, the liquid level is detected to recognize the amount of water to be used as the target volume. It is. Such water supply divided into two times is performed in the same manner in a predetermined additional dissolving step and an optional additional dissolving step which will be described later.
[0032]
In the above dialysis stock solution preparation process, when the set number of drugs has not been dissolved (that is, when the required amount is insufficient), the following additional dissolution process (hereinafter, the additional dissolution process in this case is added as a default) This is called a dissolution process.
After the valves V1, V6, and V4 are opened and water is supplied into the main tank 1, an additional amount of powdered drug for dialysis is put into the main tank 1 and the pump P is driven. The timing of adding the additional dialysis powder drug may be any water supply to the main tank 1, and it is preferable to display an input instruction to the operator from an operation panel (not shown).
Thereby, the water from the water supply means 10 is supplied from the bottom into the main tank 1 through the lines L1, L2, L3, L4, L12, and L8, and a part of them is diverted from the line L12, It is supplied from the top into the main tank 1 through L11 and L10.
[0033]
On the other hand, since the valve V4 is opened, during the predetermined additional dissolution process in the main tank 1, the dialysate stock solution starts to be supplied from the sub tank 2 to the dialysate supply device 11 via the lines L13, L15, and L17.
Then, the volume of the dialysis stock solution in the main tank 1 is detected again by the liquid level detection means 3, and a value obtained by subtracting the dialysis stock solution in the main tank 1 detected immediately before from this detection value is additionally input. The predetermined additional dissolution process is terminated when the volume corresponding to the powder drug for dialysis is reached.
[0034]
In order to perform dialysis, the valve V3 is opened to open the supply line, thereby feeding the dialysis stock solution in the main tank 1 to the dialysis solution supply device 11 (dialysis stock solution supplying step). Alternatively, the valve V3 may be opened to open the supply line, and the dialysis stock solution in the sub tank 2 may be sent to the dialysate supply device 11. That is, it is possible to appropriately select whether to use the dialysis stock solution in the main tank 1 first or the dialysis stock solution in the sub tank 1 first.
[0035]
When it is necessary to make additional dialysis stock solution during the dialysis stock supply process (that is, when the required amount is insufficient), the following additional dissolution process (hereinafter, the additional dissolution process in this case is especially optional additional dissolution) Process). When the dialysis stock solution required for the time required for the optional additional dissolution step does not remain in the sub tank 2, the dialysis stock solution in the main tank 1 needs to be transferred to the sub tank 2 in advance.
[0036]
First, the volume of the dialysis stock solution remaining in the main tank 1 is detected by the liquid level detection means 3 (the detection method has already been described). Next, the valves V1, V6, and V4 are opened and water is supplied into the main tank 1, and then an additional amount of the dialysis powder drug is introduced into the main tank 1 to drive the pump P. The timing of adding the additional dialysis powder drug may be any water supply to the main tank 1, and it is preferable to display an input instruction to the operator from an operation panel (not shown).
Thereby, the water from the water supply means 10 is supplied from the bottom into the main tank 1 through the lines L1, L2, L3, L4, L12, and L8, and a part of them is diverted from the line L12, It is supplied from the top into the main tank 1 through L11 and L10.
[0037]
On the other hand, since the valve V4 is opened, the dialysate stock solution continues to be supplied from the sub tank 2 to the dialysate supply device 11 via the lines L13, L15, and L17 during the optional additional dissolution process in the main tank 1. .
Then, the volume level of the dialysis stock solution in the main tank 1 is detected again by the liquid level detection means 3, and a value obtained by subtracting the dialysis stock solution remaining in the main tank 1 detected immediately before from this detection value is additionally input. The optional additional dissolution step is terminated when the volume corresponding to the powdered dialysis drug is reached.
In the default additional dissolution process and the optional additional dissolution process, if there is no dialysis stock solution remaining in the main tank 1 (when the main tank 1 is empty), the valve V8 is opened before water supply or during water supply. It is preferable to drain the stock solution for dialysis remaining inside.
[0038]
Next, the cleaning / disinfecting process in the main tank 1 and the sub tank 2 will be described.
Washing in the sub-tank 2 is a state in which the dialysis stock solution does not remain in the sub-tank 2 (including when the dialysis stock solution is used up and when the drain line is opened by opening the valve V5 and the dialysis stock solution is drained) And during the supply of the dialysis stock solution by the main tank 2.
[0039]
That is, the valve V7 is opened and the water in the water supply means 10 is sprinkled and washed in the sub tank 2 in the shower 5, and the valve V3 is opened to release the supply line, so that the dialysis stock solution in the main tank 1 is dialyzed. Supply to the supply device 11. Incidentally, the valve V6 is opened, the line reaching the supply line via the lines L12 and L4 is released, and the dialysis stock solution in the main tank 1 is also supplied to the dialysis supply device 11 through the line. The water sprayed from the shower 5 is drained by the drainage line released by opening the valve V5.
[0040]
Washing in the main tank 1 is performed after the dialysis on the first day is completed, and is performed in a state in which the powder drug for dialysis necessary for dialysis on the next day is put in the sub tank 2. That is, the valve V2 is opened and the water in the water supply means 10 is sprinkled and washed in the sub tank 2 in the shower 4, and the pump P is driven to circulate the water used for washing in the main tank 1. By this circulation, it is possible to clean the line in which the circulating water is flowed. Note that the valve V6 may be opened as necessary during cleaning to clean the line including the line L12.
[0041]
Further, by disinfecting the disinfecting unit 7 and flowing the disinfecting liquid into the main tank 1, disinfection in the main tank 1 can be performed. This disinfection is preferably performed between a plurality of cleanings in order to avoid the disinfectant remaining.
Further, by opening the valve V3 and driving the pump P, the water in the main tank 1 is circulated in the line formed by the lines L6, L3, L16, and L18, and the chamber 12 is cleaned. If such a line is formed during the disinfection of the main tank 1, the chamber can be disinfected. Although the water after cleaning or disinfection is discharged by opening the valve V8, cleaning or disinfection is performed with the valve 5 open so that water for disinfection or the like is not mixed into the dialysis powder medicine in the sub tank 2. It is preferred to do so.
[0042]
According to the dissolution apparatus, the powder drug for dialysis can be put into the sub tank 2 on the day before dialysis, and the dissolution work to be performed on the dialysis day can be reduced. Further, since only one liquid level detecting means 3 is provided on the main tank 1 side, the total volume of the prepared dialysis stock solution can be detected. It is possible to reduce the maintenance work for the liquid level detecting means.
[0043]
In addition, the sub-tank 2 can be reduced in capacity because the use of the powdered dialysis drug in the dialysis stock solution preparation process and the supply of the dialysis stock solution in the additional dissolution process can be reduced. Can be
[0044]
As described above, the dissolution apparatus according to the present embodiment has been described. However, the dialysis stock solution preparation step, the default additional dissolution step, the optional additional dissolution step, the dialysis stock solution supply step, and the cleaning / disinfecting step may be manually switched. You may comprise so that a process may be switched automatically by sequence control etc.
[0045]
【The invention's effect】
According to the first aspect of the present invention, since the total volume of the dialysis stock solution produced by detecting the liquid level of the dialysis stock solution in the main tank of the two dissolution tanks of the main tank and the sub tank is calculated, It suffices to arrange the detection means only in the main tank, so that the manufacturing cost of the apparatus can be reduced and the maintenance work can be reduced.
[0046]
According to the invention of claim 2, since the subtank can be washed and disinfected while supplying the dialysis stock solution dissolved in the dialysis stock solution preparation step by the dialysis stock solution supply step, the dialysis of the day was completed. The dialysis powder drug for dialysis of the next day can be prepared in the sub tank immediately after that, and the workability of dissolving the dialysis stock solution can be improved. Since the stock solution is supplied, the sub-tank can be washed and disinfected without affecting dialysis.
According to the invention of claim 3, since the stock solution for dialysis is supplied even during the additional dissolution step, the stock solution for dialysis can be additionally dissolved without affecting the dialysis.
[Brief description of the drawings]
FIG. 1 is a schematic system diagram of a melting apparatus according to the present invention.
DESCRIPTION OF SYMBOLS 1 ... Main tank 1a-1e ... Opening 2 ... Sub tank 2a, 2b ... Opening 3 ... Liquid level detection means 4, 5 ... Shower 6 ... Connection line 7 ... Disinfection unit 8 ... Concentration cell 9 ... Calculation means 10 ... Water supply means 11 ... Dialysate supply device 12 ... chamber F1 ... filters L1-L18 ... lines V1-V8 ... valve P ... pump

Claims (3)

In a dissolution apparatus for dissolving a powder drug for dialysis and obtaining a stock solution for dialysis,
A main tank having liquid level detection means for detecting the level of the stored dialysis stock solution;
A sub-tank containing the dialysis powder drug and having a smaller capacity than the main tank;
A water supply line for supplying water for dissolving the powder drug for dialysis to the sub tank;
An opening formed in the side wall of the main tank and an opening formed in the side wall of the sub tank are connected, and when the liquid level of the dialysis stock solution reaches the opening in the sub tank, the dialysis stock solution By overflowing the main tank to the main tank, the connection line for flowing the stock solution for dialysis exceeding the predetermined liquid level into the main tank,
Calculation means for calculating the total volume of the dissolved dialysis stock solution from the known volume converted from the predetermined liquid level of the sub tank and the volume calculated from the liquid level detected by the liquid level detection means; ,
A supply line for feeding the dialysis stock solution in the main tank or sub tank to a dialysate supply device;
And providing a communication line for communicating the main tank and the water supply line,
The dialysis stock solution that has flowed into the main tank from the sub tank via the connection line is supplied to the sub tank again through the communication line and the water supply line, so that the dialysis stock solution is provided between the main tank and the sub tank. The melting apparatus is configured to be able to circulate. The powder medicine for dialysis previously charged in the sub-tank is dissolved with water from the water supply line, and the liquid level detection means detects the liquid level of the dialysis stock solution that has flowed out to the main tank through the connection line. Then, based on the detection result, the calculation means calculates the volume of the dialysis stock solution, and controls the water supply line so as to obtain a predetermined concentration to obtain a dialysis stock solution preparation step. When,
After the dialysis stock solution preparatory operation, a dialysis stock solution supplying step of feeding the dialysis stock solution from the main tank or sub tank to the dialysate supply device via the supply line;
A cleaning / disinfecting step for cleaning or disinfecting the sub-tank while feeding the dialysis stock solution from the main tank to the dialysate supplying device during the dialysis stock solution supplying step;
After the washing step, a dialysis powder drug charging step of charging the dialysis powder drug for the next dialysis into the sub tank;
The method of using the dissolution apparatus according to claim 1, wherein:   When the dialysis stock solution obtained by the dialysis stock solution preparation step is smaller than the required amount, the main tank is supplied with the dialysis stock solution from the sub tank to the dialysate supply device instead of the dialysis stock solution supply step. 3. The method for using a dissolution apparatus according to claim 2, wherein an additional dissolution step of additionally dissolving the stock solution for dialysis is performed.

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