JP2002506821A - 皮膚刺激の治療方法 - Google Patents
皮膚刺激の治療方法Info
- Publication number
- JP2002506821A JP2002506821A JP2000536381A JP2000536381A JP2002506821A JP 2002506821 A JP2002506821 A JP 2002506821A JP 2000536381 A JP2000536381 A JP 2000536381A JP 2000536381 A JP2000536381 A JP 2000536381A JP 2002506821 A JP2002506821 A JP 2002506821A
- Authority
- JP
- Japan
- Prior art keywords
- skin
- vitamin
- compound
- safe
- effective amount
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 206010040880 Skin irritation Diseases 0.000 title abstract 2
- 230000036556 skin irritation Effects 0.000 title abstract 2
- 231100000475 skin irritation Toxicity 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 claims abstract 18
- 229930003270 Vitamin B Natural products 0.000 claims abstract 16
- 235000019156 vitamin B Nutrition 0.000 claims abstract 16
- 239000011720 vitamin B Substances 0.000 claims abstract 16
- 150000001875 compounds Chemical class 0.000 claims abstract 13
- 210000003491 skin Anatomy 0.000 claims 14
- 239000002085 irritant Substances 0.000 claims 6
- 231100001067 mild skin irritation Toxicity 0.000 claims 5
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 claims 4
- 229940126062 Compound A Drugs 0.000 claims 3
- NLDMNSXOCDLTTB-UHFFFAOYSA-N Heterophylliin A Natural products O1C2COC(=O)C3=CC(O)=C(O)C(O)=C3C3=C(O)C(O)=C(O)C=C3C(=O)OC2C(OC(=O)C=2C=C(O)C(O)=C(O)C=2)C(O)C1OC(=O)C1=CC(O)=C(O)C(O)=C1 NLDMNSXOCDLTTB-UHFFFAOYSA-N 0.000 claims 3
- XLOMVQKBTHCTTD-UHFFFAOYSA-N Zinc monoxide Chemical compound [Zn]=O XLOMVQKBTHCTTD-UHFFFAOYSA-N 0.000 claims 2
- 229960003512 nicotinic acid Drugs 0.000 claims 2
- 235000001968 nicotinic acid Nutrition 0.000 claims 2
- 239000011664 nicotinic acid Substances 0.000 claims 2
- 206010012442 Dermatitis contact Diseases 0.000 claims 1
- 230000003444 anaesthetic effect Effects 0.000 claims 1
- 230000003110 anti-inflammatory effect Effects 0.000 claims 1
- 230000003064 anti-oxidating effect Effects 0.000 claims 1
- 230000001139 anti-pruritic effect Effects 0.000 claims 1
- 239000003963 antioxidant agent Substances 0.000 claims 1
- 230000003078 antioxidant effect Effects 0.000 claims 1
- 239000003908 antipruritic agent Substances 0.000 claims 1
- 208000010247 contact dermatitis Diseases 0.000 claims 1
- 239000003246 corticosteroid Substances 0.000 claims 1
- GVJHHUAWPYXKBD-UHFFFAOYSA-N d-alpha-tocopherol Natural products OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 150000002148 esters Chemical class 0.000 claims 1
- 231100000021 irritant Toxicity 0.000 claims 1
- 230000003472 neutralizing effect Effects 0.000 claims 1
- -1 nicotinamide, nicotinamide derivatives Chemical class 0.000 claims 1
- 230000001590 oxidative effect Effects 0.000 claims 1
- 210000004927 skin cell Anatomy 0.000 claims 1
- 230000003637 steroidlike Effects 0.000 claims 1
- 229960001295 tocopherol Drugs 0.000 claims 1
- 229930003799 tocopherol Natural products 0.000 claims 1
- 235000010384 tocopherol Nutrition 0.000 claims 1
- 239000011732 tocopherol Substances 0.000 claims 1
- 230000000304 vasodilatating effect Effects 0.000 claims 1
- 239000011787 zinc oxide Substances 0.000 claims 1
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/673—Vitamin B group
- A61K8/675—Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/75—Anti-irritant
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7809298P | 1998-03-16 | 1998-03-16 | |
| US60/078,092 | 1998-03-16 | ||
| US9216898P | 1998-07-09 | 1998-07-09 | |
| US60/092,168 | 1998-07-09 | ||
| PCT/US1999/005411 WO1999047141A1 (en) | 1998-03-16 | 1999-03-12 | Method of treating skin irritation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JP2002506821A true JP2002506821A (ja) | 2002-03-05 |
Family
ID=26760107
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000536381A Pending JP2002506821A (ja) | 1998-03-16 | 1999-03-12 | 皮膚刺激の治療方法 |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1063994A1 (zh) |
| JP (1) | JP2002506821A (zh) |
| CN (1) | CN1292699A (zh) |
| AU (1) | AU3082699A (zh) |
| WO (1) | WO1999047141A1 (zh) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004519413A (ja) * | 2000-04-14 | 2004-07-02 | ナイアダイン コーポレーション | 局所微量栄養素送達システムおよびその用途 |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000012059A1 (en) * | 1998-08-27 | 2000-03-09 | The Procter & Gamble Company | Methods of reducing the irritation associated with vitamin b3 compositions |
| US6444647B1 (en) | 1999-04-19 | 2002-09-03 | The Procter & Gamble Company | Skin care compositions containing combination of skin care actives |
| US7196022B2 (en) | 2001-12-20 | 2007-03-27 | Kimberly-Clark Worldwide, Inc. | Products for controlling microbial generated odors |
| US7851477B2 (en) * | 2003-05-22 | 2010-12-14 | L'oreal | Method for the treatment of skin |
| MX2007004280A (es) * | 2004-10-15 | 2007-05-16 | Bayer Consumer Care Ag | Composiciones acidas y tamponadas para el cuidado de la piel que comprenden nicotinamida y un agente absorbente. |
| US20070213409A1 (en) * | 2005-03-24 | 2007-09-13 | Beiersdorf Ag | Use of preparations for skin enzyme protection |
| FR2903303B1 (fr) * | 2006-07-07 | 2011-12-09 | Labo Dermatologiques D'uriage | Compositions dermatologiques et/ou cosmetologiques destinees a lutter contre le vieillissement cutane |
| DE102007056424A1 (de) * | 2007-11-23 | 2009-05-28 | Neopharmacie Gmbh | Pharmazeutische Zusammensetzung, enthaltend eine Öl/Wasser-Emulsion |
| WO2009118371A1 (en) | 2008-03-28 | 2009-10-01 | Janssen Pharmaceutica Nv | Use of nicotinamide for treating summer itch in horses |
| ES2741656T3 (es) | 2012-12-14 | 2020-02-11 | Unilever Nv | Niacinamida para inducir la generación de péptidos antimicrobianos |
| CA3000880A1 (en) | 2015-10-05 | 2017-04-13 | Unilever Plc | A skin lightening composition |
| US10660838B2 (en) | 2017-06-23 | 2020-05-26 | The Procter & Gamble Company | Composition and method for improving the appearance of skin |
| US10874600B2 (en) | 2018-06-18 | 2020-12-29 | The Procter & Gamble Company | Method for degrading bilirubin in skin |
| CA3102288A1 (en) | 2018-07-03 | 2020-01-09 | The Procter & Gamble Company | Method of treating a skin condition |
| WO2020089236A1 (en) | 2018-11-02 | 2020-05-07 | Unilever Plc | Bioenergetic nicotinic acid glycerol esters, compositions and methods of using same |
| EP4093368A1 (en) | 2020-01-24 | 2022-11-30 | The Procter & Gamble Company | Skin care composition |
| US10959933B1 (en) | 2020-06-01 | 2021-03-30 | The Procter & Gamble Company | Low pH skin care composition and methods of using the same |
| US11583488B2 (en) | 2020-06-01 | 2023-02-21 | The Procter & Gamble Company | Method of improving penetration of a vitamin B3 compound into skin |
| EP4259083A1 (en) | 2020-12-14 | 2023-10-18 | The Procter & Gamble Company | Method of treating oxidative stress in skin and compositions therefor |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4505896A (en) * | 1979-04-19 | 1985-03-19 | Elorac, Ltd. | Method of treating acne vulgaris and composition |
| JPH0232006A (ja) * | 1988-07-21 | 1990-02-01 | Shiseido Co Ltd | 皮膚外用剤 |
| JPH09104623A (ja) * | 1995-08-08 | 1997-04-22 | Sekisui Chem Co Ltd | 皮膚疾患治療用外用剤 |
| CN1133417C (zh) * | 1996-04-23 | 2004-01-07 | 普罗克特和甘保尔公司 | 维生素b3化合物调节皮肤外观的方法 |
-
1999
- 1999-03-12 CN CN998037796A patent/CN1292699A/zh active Pending
- 1999-03-12 AU AU30826/99A patent/AU3082699A/en not_active Abandoned
- 1999-03-12 WO PCT/US1999/005411 patent/WO1999047141A1/en not_active Application Discontinuation
- 1999-03-12 JP JP2000536381A patent/JP2002506821A/ja active Pending
- 1999-03-12 EP EP99912455A patent/EP1063994A1/en not_active Withdrawn
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004519413A (ja) * | 2000-04-14 | 2004-07-02 | ナイアダイン コーポレーション | 局所微量栄養素送達システムおよびその用途 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1063994A1 (en) | 2001-01-03 |
| WO1999047141A1 (en) | 1999-09-23 |
| AU3082699A (en) | 1999-10-11 |
| CN1292699A (zh) | 2001-04-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20040519 |
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| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20040601 |
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| A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20041026 |