JP2001261576A - Cleaning method using liquid oral composition - Google Patents

Abstract

(57) [Summary] [PROBLEMS] By using after removing food residues, it is possible to sufficiently wash and remove oral bacteria and residues that could not be removed by removing food residues, and adhere gingivitis, periodontitis and plaque. The present invention provides a method for cleaning teeth with a liquid oral composition that can prevent oral diseases such as SOLUTION: A cleaning method characterized by using a liquid oral composition containing a bactericide and an anti-inflammatory agent after removing food residues from teeth to prevent plaque adhesion and gingivitis. As the bactericide, a cationic surfactant is preferable, as the anti-inflammatory agent, glycyrrhizinate is preferable, and the amount of the liquid oral composition used is preferably 5 to 25 ml.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a method for cleaning teeth and a method for cleaning the mouth using a liquid oral composition which is simple to use, and more particularly to a method for cleaning teeth after removing food residues. The present invention relates to a method for preventing oral diseases such as plaque adhesion and gingivitis.

[0002]

2. Description of the Related Art Conventionally, it has been considered that gingivitis and plaque can be prevented by brushing with a dentifrice. Since the effect of this tooth brushing can be exerted by performing correct and accurate brushing, it is necessary to acquire a correct brushing method. However, ordinary people brush every day, but the brushing method is inexperienced so that they are not polished neatly. For this reason, although the teeth are brushed daily, oral bacteria and residues that cannot be removed by brushing remain, and these brushes are left behind, resulting in oral diseases.

[0003]

SUMMARY OF THE INVENTION An object of the present invention is to provide a method which is simple to use and effective in preventing oral diseases in view of the above situation.

[0004]

Means for Solving the Problems The present inventors have conducted various studies to solve the above-mentioned problems, and even when immature brushing is not performed, the unpolished residue is thoroughly washed and removed to prevent oral diseases. As a result of intensive studies on the method, by using a liquid oral composition containing a bactericide and an anti-inflammatory agent after removing food residues, washing and removing oral bacteria and residues that could not be removed by tooth brushing, plaque adhesion, It has been found that a method for preventing gingivitis is effective. By using this method, the present invention has been completed, focusing on the fact that even an inexperienced brushing technique can sufficiently prevent oral diseases.

The present invention has solved the above-mentioned problems by the following means. (1) A cleaning method characterized by using a liquid oral composition containing a bactericide and an anti-inflammatory agent after removing food residues from teeth to prevent plaque adhesion and gingivitis. (2) The cleaning method according to (1), wherein the germicide is a cationic surfactant. (3) The cleaning method according to the above (1), wherein the anti-inflammatory agent is glycyrrhizinate. (4) The cleaning method according to (1), wherein the amount of the liquid oral composition used after the removal of the food residue is 5 to 25 ml. (5) A liquid oral composition to be used after removing food residues trapped in teeth, the liquid oral composition containing a mixture of a bactericide and an anti-inflammatory agent as an active ingredient to prevent plaque adhesion and gingivitis. object.

[0006]

DESCRIPTION OF THE PREFERRED EMBODIMENTS Specific examples of the liquid oral composition according to the present invention include mouthwashes, mouth fresheners and the like. The use amount of such a liquid oral cavity composition (hereinafter also referred to as mouthwash or mouthwash as appropriate) per use is preferably 5 to 25 ml. If the amount is less than 5 ml, the mouthwash does not spread in the oral cavity, and the washing effect is low. If the amount is more than 25 ml, the mouthwash is too large to perform sufficient mouthwash. In addition, in the case of a child who has not yet brushed, it is effective to set the usage amount to 5 to 10 ml.

As the solvent of the present invention, the amount of water is often the largest in the solvent contained in the liquid oral composition. For example, the amount of water contained in the solvent is usually 50 to 95. % (Mass, hereinafter simply referred to as "%"). Other solvents, such as alcohols, may be included in smaller amounts than water. For example, the amount of alcohol contained in the solvent is usually 0 to 30%. As the solvent, water such as purified water, ionized water and distilled water, alcohol such as ethanol and various denatured alcohols can be used, and the solvent does not contain harmful components such as methanol.

[0008] Disinfectants include decalinium chloride, benzethonium chloride, benzalkonium chloride, cetylpyridinium chloride, alkyldiaminoethylglycine hydrochloride, chlorhexidine hydrochloride, chlorhexidine gluconate,
Triclosan, isopropylmethylphenol and the like are preferable, and benzethonium chloride, benzalkonium chloride and cetylpyridinium chloride are preferable, and the compounding amount is preferably in a range of 0.01 to 0.1% by volume. Examples of the anti-inflammatory agent include aminocaproic acid, allantoin and its derivatives, glycyrrhizic acid and its derivatives, glycyrrhetinic acid and its derivatives, ascorbic acid and its salts, vitamin E (tocopherol), and anti-inflammatory enzymes such as lysozyme chloride, and preferably glycyrrhizin. Dipotassium acid, and its compounding amount is preferably in the range of 0.01 to 0.1% by volume.

[0009] The liquid oral composition used in the present invention may be mixed with various components applicable to the oral cavity, such as fragrances, detergents and wetting agents. As these, conventionally known ones can be used as long as they do not reduce the feeling of use or impair the effects of the invention. Examples of such components are shown below. As a substance having a tooth surface strengthening action, sodium fluoride, fluorophosphate, fluoride ion source such as fluoroborate, calcium phosphate, phosphate ion source such as hydroxyapatite, humectants such as glycerin, propylene glycol, sorbit, Foaming agents such as sodium lauryl sulfate, steviaside, xylitol, erythritol, sorbitol,
Sweeteners such as saccharin sodium, preservatives such as parahydroxybenzoate and sodium benzoate,

Polyoxyethylene hydrogenated castor oil, polyoxyethylene / polyoxypropylene block polymer, polyoxyethylene / polyoxypropylene alkyl ether, polyoxyethylene / alkyl ether,
Polyoxyethylene alkylphenyl ether, polyoxyethylene fatty acid ester, polyoxyethylene higher alcohol ether, polyoxyethylene polyoxypropylene fatty acid ester, polyoxyethylene sorbitan fatty acid ester, polyoxyethylene sorbit fatty acid ester, sorbitan fatty acid ester, poly Non-ionic surfactants such as oxyethylene sorbitan monolaurate, glycerin fatty acid ester, polyglycerin fatty acid ester, propylene glycol fatty acid ester,

[0011] Sodium lauryl sulfate, sodium myristyl sulfate, polyoxyethylene alkyl ether sulfate, sodium lauroyl sarcosine, myristoyl sarcosine sodium, alkyl ether carboxylate, alkyl phosphate, polyoxyethylene alkyl ether phosphate, N- Anionic surfactants such as acyltaurine salts, polyoxyethylene alkyl ether phosphates / phosphates, sulfonates, alkyltrimethylammonium chloride, dialkyldimethylammonium chloride, cetylpyridinium chloride, benzethonium chloride, benzalkonium chloride, poly Cationic surfactants such as oxyethylene alkylamine and fatty acid amide,

In addition, dextranase, mutanase, azulene, azulene sulfonic acid, dihydrocholesterol, epidihydrocholesterine, oak extract,
Touki Soft Extract, Hinokitiol, Allantoin, Allantoin Chlorhydroxyaluminum, Sodium Chloride, dl-α-Tocopherol Acetate, dl- Nicotinic Acid
As a flavor such as α-tocopherol, epsilon aminocaproic acid, tranexamic acid, polyphosphate, thymol, sodium copper chlorophyllin, wax, shellac, peppermint oil, peppermint oil, menthol, carvacrol, eucalyptus oil, eugenol, etc.

As the chelating agent, for example, sodium tripolyphosphate, sodium pyrophosphate, edetate disodium, phytic acid and the like can be mentioned. In particular, sodium pyrophosphate and disodium edetate are preferably used. The liquid oral composition used in the present invention can be used as a mouthwash or a freshener in the mouth by washing the mouth with an appropriate amount contained therein. However, in the present invention, gingivitis, periodontitis and adhesion of plaque cannot be prevented with a mouthwash alone, and an auxiliary effect effective for improving the effect can be obtained by washing after removing food residues. Things.

[0014]

EXAMPLES Hereinafter, the present invention will be described in detail with reference to examples, but the present invention is not limited to these examples.

Example 1 and Comparative Example 1 Liquid oral compositions having the formulations shown in the following Table 1 were prepared: mouthwash A (formulation of the present invention) and mouthwash B (formulation of Comparative Example). .

[0016]

[Table 1]

Subjects with gingivitis (total 20)
After brushing with a toothpaste containing no disinfectant and anti-inflammatory agent, the mouth was washed with a mouthwash A containing a disinfectant and an anti-inflammatory agent or a mouthwash B without placebo (placebo) for 4 weeks. Let it use, the degree of plaque adhesion before and after use,
The degree of gingivitis was examined by a dentist. The results are shown in Tables 2 and 3. The mouthwash A of the present invention shows a lower value in both plaque adhesion and the degree of gingivitis,
The effect of suppressing plaque adhesion and gingivitis was observed.

Evaluation criteria 1) Plaque adhesion: Criterion 0; no plaque 1: plaque in the form of a thin film exists, but plaque is recognized before the probe only after sliding the tooth surface with the probe Thing 2: plaque adheres to the extent visible to the naked eye 3; plaque adheres thickly, interdental space is filled with plaque 2) Extent of gingivitis: criteria 0; no gingival inflammation is observed 1: mild inflammation 2: moderate inflammation 3; hardness inflammation

[0019]

[Table 2]

[0020]

[Table 3]

Formulation Examples 1 to 5 Five formulations were prepared as the liquid oral composition (mouthwash) of the present invention. The compositions of these formulations are shown in Tables 4-8.

[0022]

[Table 4]

[0023]

[Table 5]

[0024]

[Table 6]

[0025]

[Table 7]

[0026]

[Table 8]

[0027]

According to the present invention, since a liquid oral composition containing a bactericide and an anti-inflammatory agent is used after removing food residues, it is possible to sufficiently remove bacteria and residues in the oral cavity that could not be removed by, for example, brushing alone. Can be removed by washing. Oral diseases such as plaque adhesion and gingivitis can be prevented. In particular, a remarkable effect can be obtained as compared with the case where neither brushing nor cleaning is performed.

 ──────────────────────────────────────────────────続 き Continued on the front page F term (reference) 4C083 AA072 AB032 AB282 AC102 AC122 AC182 AC432 AC482 AC622 AC692 AD042 AD252 AD531 AD532 BB06 BB60 CC41 DD27 EE33 4C084 AA20 BA44 MA57 NA14 ZA671

Claims (5)

[Claims] 1. A cleaning method comprising using a liquid oral composition containing a bactericide and an anti-inflammatory agent after removing food residues from teeth to prevent plaque adhesion and gingivitis. 2. The cleaning method according to claim 1, wherein the germicide is a cationic surfactant. 3. The cleaning method according to claim 1, wherein the anti-inflammatory agent is glycyrrhizinate. 4. The cleaning method according to claim 1, wherein the amount of the liquid oral composition used after removing the food residue is 5 to 25 ml. 5. A liquid oral composition to be used after removal of food residues trapped in teeth, the liquid oral composition comprising a mixture of a bactericide and an anti-inflammatory agent as an active ingredient and preventing plaque adhesion and gingivitis. Composition.