JP2001258926A - Release sheet for patch - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a release sheet for a patch capable of being simply separated merely by pulling or rubbing the sheet to right and left sides and being clearly adhered without contaminating hands simply even by a person of advanced age and without wrinkle and suitable for a mass productivity at a low cost. SOLUTION: The release sheet for the patch comprises nicks formed at a predetermined interval.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

TECHNICAL FIELD The present invention relates to a patch release sheet used for a patch. More specifically, the present invention relates to a highly convenient release sheet for a patch that can be easily and cleanly stuck to an affected part even by elderly people without dirtying hands and without wrinkling.

[0002]

2. Description of the Related Art In recent years, with the aging society progressing, various computers have been used for rationalization of office work, and as a result, the number of people who complained of pain in the lower back, shoulders, knees, elbows, etc. has been increasing,
Patches such as compresses and plasters are widely used as the symptomatic treatment. Hereinafter, a conventional release sheet for patches used for patches will be described with reference to the drawings.
FIG. 11 is a perspective view showing a patch using a conventional release sheet for patches. In FIG. 11, 11 is a patch, 12
Is a support made of a white or flesh-colored nonwoven fabric, 13 is a plaster containing a drug or the like spread on substantially the entire surface of one side of the support 12, and 14 is an extremely thin paste adhered to the entire surface of the plaster 13. It is a conventional release sheet for patches made of a transparent synthetic resin film having flexibility. A method of using the patch using the conventional release sheet for patches configured as described above will be described below. First, the corners of the support 12 are searched many times with nails so that the plaster 13 and the release sheet 14 are easily peeled off, and then the release sheet 14 is peeled off with nails.
After peeling off the release sheet 14 while paying attention so that the support 12 is not kinked and the ship plasters are not entangled, the support 12 is used to be attached to the affected part with the support 12.

[0003]

However, the above-mentioned conventional release sheet for patches has the following problems. That is, (1) After the patch has spread the plaster on substantially the entire surface of one side of the support, the raw sheet obtained by sticking a release sheet on the upper surface of the plaster is cut into a square shape or the like. Since the outer peripheral cross-section of the support, the plaster, and the release sheet are flush with each other, there is no clue to start peeling when peeling the release sheet from the outer edge. However, there was a problem that the peeling operation was difficult and it was difficult to use. (2) Since the plaster contains a thickener in order to impart a thickening effect to the skin and the like, the plaster has extremely strong tackiness and is hardly peeled off with a conventional release sheet for patches. There was a problem that. (3) Almost all patches such as poultices and plasters are, for example, extremely thin and flexible release sheets on the surface of a white support and a white or white transparent paste applied on the support. , It is difficult to distinguish between the release sheet and the plaster, and the release position is unclear, so that the release sheet is difficult to pick up. (4) For this reason, even if a patient tries to affix to the affected area, the peeling sheet is difficult to peel off, and time is wasted unnecessarily to peel off the peeling sheet. There was a problem that it was very inconvenient. (5) Especially for elderly people, fingertips are not dexterous,
In addition, since the visual acuity and the like are also reduced, the thin transparent release sheet has the same color and adheres to the plaster, so it is difficult to peel off and peeling the release sheet from the plaster imposes a heavy burden. Had. (6) In addition, since both the release sheet and the support are flexible, the support is kinked and the plasters are entangled with each other and cannot be used. To solve these problems,
For example: a. The release sheet is provided with a cut portion or a cut portion, and the peeling is performed from the cut portion or the cut portion (actually disclosed as 5-
No. 42811), b. One using a release sheet having a larger area than the plaster, c. A proposal has been made in which two release sheets are superimposed at a substantially central portion of a plaster, and peeling is performed from an overlapped portion that does not contact the plaster. However,
The above-mentioned conventional release sheet for patches had the following problems. (7) When the release sheet of the above a is provided with a cut portion, the release sheet is turned up from the cut portion except during use, and the medicinal component contained in the plaster volatilizes from the turned up portion. Therefore, there is a problem that a medicinal effect cannot be obtained. (8) Further, in the case where the cut portion is provided in the release sheet, there is a problem that it is difficult to cut the release sheet neatly depending on the material of the release sheet and the interval between the cut portions. (9) When the release sheet of the above b is formed with a larger area than the plaster, a large area of the release sheet is required, so that the cost becomes high. After cutting the anti-sheet, it is necessary to further cut off the support and the plaster at the outer edge of the patch, which has a problem that the workability is poor and the productivity is inferior to that extent. (10) When the two release sheets of the above c are superimposed at the substantially central portion of the plaster, there is a problem that a large number of production steps are required, work efficiency is low, product yield is reduced, and productivity is low. Had. (11) Further, the release sheet used for the patch is usually formed without any irregularities or the like in many cases, and has a problem that the release sheet is easily slipped when peeled, and is difficult to peel. (12) Also, when manufacturing a patch, even if an attempt is made to stick a release sheet on a plaster, it cannot be stuck well, and if it is cut, it is caught in a cutting machine and easily slips off from the plaster. There was a problem that the yield was low. (13) Further, there is a problem that air bubbles are easily generated between the paste body and the paste body and the release sheet, and the yield is reduced.

SUMMARY OF THE INVENTION The present invention solves the above-mentioned conventional problems. The release sheet can be easily cut only by pulling or rubbing the release sheet to the left and right, so that even elderly people can easily clean their hands without wrinkles. It is an object of the present invention to provide a release sheet for a patch that can be stuck neatly without being wrinkled and that is suitable for mass production at low cost.

[0005]

The release sheet for a patch according to the first aspect of the present invention has a structure having cuts formed at predetermined intervals. This has the following effects. (1) Since the release sheet is provided with a cut portion having a predetermined length of the connecting portion, only the release sheet can be easily separated at the cut portion. (2) At the time of division, the part where the release sheet is divided by elasticity is turned up, so that the release sheet can be peeled off by picking up each piece of the peeled-up release sheet. (3) When each piece of the release sheet is picked, the exposed portion of the plaster can be attached only to the affected part without soiling the hands. (4) Since the peeling sheet is turned up and a part of the plaster is exposed, the exposed part of the plaster is applied to the affected area, and then each piece of the peeled up peeling sheet is pinched and pulled to the left and right. However, it can be stuck to the affected area neatly without trouble, without soiling the hands, and without wrinkling of the patch. (5) Only by pulling the release sheet and the support and the like to the left and right, it is possible to easily separate only the release sheet at the cut portion by utilizing the difference in elongation between the release sheet and the support and the like.

Here, as the release sheet, unstretched polypropylene (CPP), stretched polypropylene (OP)
P), plastic film such as polyethylene terephthalate (PET), polybutylene terephthalate (PBT), polyethylene, polyester, polyurethane, polyvinyl chloride, polystyrene, etc .; Foil,
Colorless or colored paper such as laminated paper obtained by laminating polyethylene or the like on kraft paper is used. The cut portion formed in the release sheet refers to a cut portion formed with a predetermined portion of the release sheet, for example, a connection portion at a predetermined interval in a dotted manner at a substantially central portion or a peripheral portion of the release sheet. is there. Further, in order to clarify the tearing method on the left and right portions of the release sheet, a display portion such as a figure such as an arrow, a character, or a symbol may be provided, or coloring may be performed. Examples of the support used for the patch using the release sheet include stretchable or non-stretchable materials such as woven fabric, knitted fabric, nonwoven fabric, and nonwoven paper. When using a stretchable material for the support, using the difference in the elongation percentage between the support and the release sheet,
By simply pulling the release sheet together with the support, the release sheet can be easily divided and the release sheet can be peeled off from the plaster. The stretchable support preferably has a stretch rate of 10 to 100% in the vertical direction and / or the horizontal direction.
In the case where a non-stretchable support is used, the release sheet can be separated by using the viscoelastic sliding of the release sheet and the plaster, and the release sheet can be peeled off from the plaster as it is.

[0007] Specific materials for these supports include:
Bast fibers such as paper, cotton, hemp and jute, cellulose fibers such as leaf vein fibers such as manila hemp, animal hair fibers such as wool, silk fibers,
Natural fibers such as protein fibers such as feather fibers, regenerated cellulose fibers such as rayon and cupra, regenerated fibers such as regenerated protein fibers, semi-synthetic fibers such as cellulose acetate fibers and promixes, nylon aramid fibers, polyethylene terephthalate fibers, and polyester fibers , Acrylic fiber, etc., polyolefin fiber such as polyethylene and polypropylene, polyvinyl alcohol fiber, polyvinyl chloride fiber, polyvinylidene chloride fiber, polyvinyl chloride fiber, polyurethane fiber, polyoxymethylene fiber, polytetrafluoroethylene fiber, polyparaphenylene Benzbisthiazole (PBT) fiber, polyimide fiber and the like can be used. The support is selected in consideration of physical properties such as thickness, elongation, tensile strength, workability, feel at the time of application, hermeticity of the affected area, transfer of the drug to the support, and the like. The plaster to which the patch release sheet is adhered is used effectively as an external patch by containing or adhering a drug to the substrate. The plaster contains water so that a sufficient medicinal effect on the skin can be obtained, and has an adhesive property, and has an appropriate cohesive property such that the plaster softens even at room temperature or higher and the plaster does not remain on the skin. It is formed as follows.

It is desirable that the thickener is capable of stably retaining water at 30% to 80% and has water retention. Specific examples thereof include plant systems such as guar gum, locust bean gum, carrageenan, alginic acid, sodium alginate, agar, arabic gum, tragacanth gum, karaya gum, pectin, starch, microbial systems such as xanthan gum, acacia gum, gelatin, collagen, Natural polymers such as animal-based, cellulose-based such as methylcellulose, ethylcellulose, hydroxyethylcellulose, and sodium carboxymethylcellulose; semi-synthetic polymers such as starch-based such as soluble starch, carboxymethylstarch, and dialdehyde starch; polyvinyl alcohol; polyvinylpyrrolidone; Vinyls such as polyvinyl methacrylate, acrylics such as polyacrylic acid and sodium polyacrylate, other polyethylene oxides,
A water-soluble polymer such as a synthetic polymer such as a methyl vinyl ether / maleic anhydride copolymer is preferably used. Particularly, sodium polyacrylate is preferred. This is because the gel strength is high and the water retention is excellent. Further, sodium polyacrylate having an average degree of polymerization of 20,000 to 70,000 is preferable. As the average degree of polymerization becomes smaller than 20,000, the thickening effect becomes poor and a sufficient gel strength cannot be obtained, and as the average degree of polymerization becomes larger than 70,000, the thickening effect becomes too strong and the workability tends to decrease. Appears, none of which is desirable. In addition, by using two or more of the above water-soluble polymers, for example, a polymer complex is formed with a strong ionic polymer of sodium polyacrylate, and an elastic gel having higher gel strength can be obtained.

As wetting agents, polyhydric alcohols such as glycerin, propylene glycol, sorbitol and the like, and as fillers, kaolin, zinc oxide, talc, titanium, bentonite, aluminum silicate, titanium oxide, zinc oxide,
Aluminum metasilicate, calcium sulfate, calcium phosphate, etc. may be added. Further, propylene carbonate, crotamiton, l-menthol, mentha oil, limonene, diisopropyl adipate and the like as a dissolution aid or absorption enhancer, and methyl salicylate, glycol salicylate, l-menthol, thymol, mint oil, Nonanilic acid wanilylamide, capsicum extract and the like may be added. Further, if necessary, a stabilizer, an antioxidant, an emulsifier, and the like may be added. Other, if necessary,
You may add a crosslinking agent, a polymerization agent, etc. The paste can be strengthened and can have water retention. The crosslinking agent and the polymerizing agent are appropriately selected depending on the type of the thickener and the like. For example, when polyacrylic acid or polyacrylate is applied as a thickener, a compound having at least two epoxy groups in a molecule, a hydrochloride such as Ca, Mg, or Al, a sulfate, a phosphate, Inorganic acid salts such as carbonate, organic acid salts such as citrate, tartrate, gluconate, stearate, oxides such as zinc oxide and silicic acid, hydroxides such as aluminum hydroxide and magnesium hydroxide And the like are preferably used. When polyvinyl alcohol is used as the thickener, adipic acid, thioglycolic acid,
Epoxy compounds (epichlorohydrin), aldehydes, N-methylol compounds, Al, Ti, Zr, Sn,
Complexes such as compounds such as V, Cu, B, and Cr are preferably used. When polyvinylpyrrolidone is used as the thickener, a methyl vinyl ether / maleic anhydride copolymer, a polyacid compound or an alkali metal salt thereof (polyacrylic acid, tannic acid and derivatives thereof) and the like are preferably used. When polyethylene oxide is used as the thickener, perchioside, polysulfone azide and the like are preferably used. When a methyl vinyl ether / maleic anhydride copolymer is used as a thickener, a polyfunctional hydroxy compound, polyamine, iodine,
Gelatin, polyvinylpyrrolidone, iron, mercury, lead salts and the like are preferably used. When gelatin is used as the thickener, aldehydes such as formaldehyde, glutaraldehyde and dialdehyde starch, diepoxides such as glyoxal and butadiene oxide, diketones such as divinyl ketone, and diisocyanates are preferably used. When sodium polyacrylate is used as a thickener, lithium hydroxide, zinc hydroxide,
It is preferable to add a polyvalent metal salt such as aluminum hydroxide and sodium borate. Particularly, zinc salts and aluminum salts are preferred. The crosslinking reaction is accelerated. The concentration of the polyvalent metal salt added as a crosslinking agent is preferably 0.5 to 1.5 equivalents per equivalent of the thickener (or water-soluble polymer). As the concentration of the polyvalent metal salt becomes smaller than 0.5 equivalent, the reaction becomes too slow and the gel strength tends to decrease, and as the concentration of the polyvalent metal salt becomes larger than 1.5 equivalent, the reaction becomes too fast. There is a tendency that the gelation becomes non-uniform and the workability tends to decrease, and neither is preferable.

As a cataplasm, it has good skin adhesion, enhances skin absorption of active ingredients, contains as much water as possible, and removes heat from the skin when water in the plaster evaporates. Deprived, this calorific value gives a refreshing feeling, and the stratum corneum is hydrated by water molecules evaporating from the inside,
The absorption of the drug is promoted, the drug is not drenched at or near room temperature, the pain is not painful when peeled off, the stain is not left, and the like. For this reason, the plaster comprises 5-20% by weight of a thickener, preferably 10-15% by weight, 5-40% by weight of a wetting agent, 20% by weight or less of a filler, and 10% by weight of water. 80% by weight, dissolution aid 0-8% by weight, drug 5% by weight or less, preferably 0.1% by weight.
It is preferably from 5% by weight to 5% by weight. When the patch is applied to a plaster or the like, the base material preferably has an acrylic copolymer, an ABA block copolymer, an alicyclic petroleum resin, or a softener. Used for Further, thermoplastic elastomers such as AB block copolymers and other polybutene rubbers, butyl rubbers, silicone rubbers, natural rubbers, styrene-butadiene copolymers, NBR polyisobutylenes, polyalkyl acrylates, synthetic isoprenes, and terpene resins , Petroleum resins, tackifiers such as rosin, hydrogenated rosin, rosin and hydrogenated rosin ester, liquid paraffin, olive oil, soybean oil, tallow, tongue and other animal and vegetable oils, polybutene, liquid polyisobutylene, lower isoprene, An adhesive / holding power regulator such as wax, a filler such as titanium oxide, zinc oxide, aluminum metasilicate, calcium sulfate, calcium phosphate, and the like are compounded. ABA type block copolymer or A-
As the B-type block copolymer, a block copolymer of a monovinyl-substituted aromatic compound A and a conjugated diolefin copolymer B is suitably used. Specifically, Kaliflex TR-1101 and Kariflex TR manufactured by Shell Chemical Co., Ltd.
-1107, Califlex TR-1111, etc., SOLPLEN 418 and SOLPLEN 3 manufactured by Philippe Petroleum
11 and the like, and its compounding amount is 10 to 40 parts by weight, preferably 15 to 30 parts by weight in the plaster composition. A-
By adding 15 to 30 parts by weight of the B-type block copolymer, the compatibility, anchoring power, and adhesive strength of the active ingredient of the ABA-type block copolymer are improved, and the cohesion by the oily component is improved. It is not preferable because these effects tend to be reduced as the ratio deviates from this range.

The drugs include methyl salicylate, glycol salicylate, 1-menthol, pepper extract,
Nonylate vanillylamide, peppermint oil, diclofenac,
Ibuprofen, indomethacin, ketoprofen, loxoprofen, sulindac, tolmetin, lobenzarit, penicillamine, fempfen, flurbiprofen, naproxen, planoprofen, thiaprofen, suprofen, felbinac, ketorolac, oxaprozin, etodolac, zaltoprofin, pirazocam hydrochloride, pentazocine hydrochloride At least one non-steroidal anti-inflammatory drug selected from buprenorphine, butorphanol tartrate and the like and ester derivatives or salts thereof,
Prednisolone, dexamethasone, hydrocortisone,
Betamethasone, fluocinide, fluocinolone acetonide, prednisolone acetate valerate, dexamethasone dipropionate, diflucortron valerate, difluprednate, betamethasone valerate, hydrocortisone butyrate, clobetasone butyrate, betamethasone butyrate, clobetasone succinate, succinate , Prednisolone 21
-(2E, 6E) steroidal anti-inflammatory drugs such as farneseat, hydrocortisone valerate, diflorazone acetate, dexamethasone propionate, betamethasone dipropionate, amcinonide, dexamethasone valerate, halcinonide, butesonide, and alclomethasone propionate; It is not limited to these. If necessary, two or more drugs can be used in combination. These drugs may be in the form of a compound derived from an ester, a compound derived from an amide, a compound derived from an acetal, or a medically acceptable inorganic or organic salt, if necessary. It may be contained or adhered to the plaster. The amount of the drug is appropriately selected according to the type and use of the patch so that an effective amount set in advance when applied to the patient can be applied to the affected area.

The release sheet for a patch according to the second aspect of the present invention has a configuration in which the release sheet has an embossed portion in the first aspect. Accordingly, the following operation is obtained in addition to the operation obtained in the first aspect. (1) Since the embossed portion is formed on the surface of the release sheet, the embossed portion increases the frictional resistance with a finger or a plaster when dividing the release sheet or manufacturing a patch. The release sheet can be easily picked by hand, or when the release sheet is pasted on the plaster spread on the support to create an original sheet, or this original sheet is cut. At times, the release sheet can be brought into close contact with the plaster, and the release sheet can be prevented from being displaced from the plaster. (2) Since the release sheet is provided with an embossed portion formed on the surface of the release sheet, the release sheet of this patch can be used without the necessity of starting peeling such as searching for a corner of the support with a nail. By simply pulling the sheet together with the support and bending the sheet at the cut, the release sheet alone can be easily cut at the cut. (3) Since the embossed portion is formed on the release sheet, the release sheet can be easily and smoothly released without slipping during the release operation. (4) Since the embossed portion is formed on the release sheet, when manufacturing the patch, when the release sheet is laminated on the plaster spread on one surface of the support, the release sheet is placed on the plaster. Lamination can be performed without slippage. (5) When the raw sheet is cut because the frictional resistance of the embossed portion is large, the raw sheet is prevented from being entangled in the cut edge cutting tool, and the release sheet does not slip, thereby improving the productivity. . (6) Even when air bubbles are generated between the plaster body and the plaster body and the release sheet, the air bubbles can be easily discharged by the embossed portion, so that the product yield can be drastically improved. .

Here, the embossed portion is formed on the entire surface or a local portion of the release sheet, for example, a portion which is easy to be picked by hand when tearing the cut portion, for example, 10 to 10 on both sides of the cut portion.
It is formed at a position such as 20 mm or an easy-to-pick position when peeling a torn release sheet. The shape of the embossed portion is not particularly limited. However, as long as it is easy to pick by hand without slipping, for example, a lattice shape, a round shape, a square shape,
It may be formed in various other shapes such as a star shape.

According to a third aspect of the present invention, there is provided the release sheet for a patch according to the first or second aspect, wherein the cut portion comprises a connecting portion (a) formed between the cut portions and the cut portion ( b) The length ratio is a: b = 1: 5 to 25. Thereby, claim 1
In addition to the effects obtained in or 2, the following effects are obtained. (1) Since the connecting portion and the cut portion are formed at a predetermined interval, the medicinal component does not volatilize and the medicinal effect is not reduced, and the reliability and convenience are excellent. (2) Since the connecting portion and the cut portion are formed at a predetermined interval, the separation sheet can be easily separated, the raw sheet can be easily cut at the time of manufacturing, and convenience and workability are improved.

Here, the cut portion formed in the release sheet has a ratio of the length of the connecting portion (a) to that of the cut portion (b).
a: b = 1: 5 to 25, preferably a: b = 1: 8 to 2
0, more preferably a: b = 1: 8-15. As the length of the cut becomes smaller than eight times the length of the connecting part, it becomes easier to break even when not in use, the medicinal component volatilizes and the medicinal effect decreases, and the release sheet becomes too thin and difficult to pick, It is not preferable because reliability and convenience tend to decrease. As the length of the cut portion becomes larger than 15 times the length of the connecting portion, the separation of the release sheet becomes difficult, and it becomes difficult to cut the raw sheet at the time of manufacturing, and the convenience and workability tend to decrease. It is undesirable because it appears.

According to a fourth aspect of the present invention, there is provided a release sheet for a patch according to any one of the first to third aspects, wherein the cut portion has a linear, S-shaped, corrugated, or saw blade shape. It has a configuration that has been formed. Thereby, the following operation is obtained in addition to the operation obtained in any one of the first to third aspects. (1) When the cut portion is formed in an S-shape, a wave shape, a saw blade shape, or the like, the protruding piece protrudes from one surface of the separated release sheet, so that the protruding piece can be easily pinched and easily. Can be peeled off. (2) If the cut portion is formed in an S-shape, a wave shape, a saw blade shape, or the like, when the release sheet is cut, the protruding portion protrudes in a cross section. Can be easily peeled off. Here, when a cut portion is formed in a predetermined portion of the release sheet in a linear shape, an S-shape, a wave shape, a saw blade shape, or the like, the protruding pieces formed at regular intervals are picked to peel the release sheet. It can be performed smoothly, and convenience such as peeling work can be improved.

According to a fifth aspect of the present invention, there is provided the release sheet for a patch according to any one of the first to fourth aspects, wherein the release sheet having the cut portion has a tensile strength.
It has a configuration of 10 g / cm to 140 g / cm. Thus, the following operation is obtained in addition to the operation obtained in any one of the first to fourth aspects. (1) During production, the release sheet can be continuously adhered to the plaster without cutting the release sheet in the middle. (2) Even when the patch is placed in the packaging bag, the yield can be further improved without the release sheet being divided.

Here, the tensile strength of the release sheet is 10
g / cm to 140 g / cm, preferably 20 g / cm to 100
g / cm, more preferably 30 g / cm to 60 g / cm. As the tensile strength of the release sheet having a cut portion becomes smaller than 30 g / cm, the release sheet is cut off in the course of production during production, making it impossible to continuously adhere the release sheet to the plaster, Also, when the agent is put into a packaging bag, the release sheet is easily cut off, and the yield tends to decrease, which is not preferable. As the tensile strength becomes greater than 60 g / cm, it becomes difficult to easily separate the release sheet when used, and the convenience tends to decrease, which is not preferable. The escape of the medicinal component and the moisture from the cut portion is prevented by applying the tension of the release sheet and overlapping the cut portions. If the difference between the extensibility ratio of the release sheet and the support is 0.3% or more, the separation is easily performed.

The release sheet for a patch according to claim 6 of the present invention has a structure according to any one of claims 1 to 5, wherein the thickness of the release sheet is 10 μm to 75 μm. Thus, the following operation is obtained in addition to the operation obtained in any one of the first to fifth aspects. (1) When peeling, the release sheet is not entangled with the plaster,
The release sheet can be easily pinched and peeled. (2) The workability and the like are improved without the release sheet being immediately cut off during production. (3) When the release sheet is attached on the plaster, the release sheet can be attached neatly without wrinkles. (4) The raw sheet can be easily cut at the time of manufacturing, and workability and the like are improved.

Here, the thickness of the release sheet is 10 μm to 7 μm.
It is preferably formed in the range of 5 μm, preferably 12 μm to 40 μm, more preferably 15 μm to 35 μm. As the thickness of the release sheet becomes smaller than 15 μm, the release sheet becomes too thin, and the release sheet is entangled with the plaster when peeling, or the release sheet is thin and slippery, which makes it difficult to pick up. When the release sheet is stuck on the plaster, the work tends to be easily wrinkled, which is not preferable. Further, as the thickness of the release sheet becomes larger than 35 μm, the release sheet becomes easy to be gripped during peeling or the like, but it becomes difficult to cut the sheet, and it becomes difficult to cut the raw sheet at the time of manufacturing, and the workability and the like tend to decrease. Appears and is not preferred.

According to a seventh aspect of the present invention, there is provided a release sheet for a patch according to any one of the first to sixth aspects, wherein the release sheet is made of unstretched or stretched polypropylene, polyethylene terephthalate, polyethylene, polyvinyl chloride. , Polyester, polyvinylidene chloride, polyester, or polystyrene synthetic resin film or sheet, or silicon-processed paper or aluminum foil. Accordingly, the following operation is obtained in addition to the operation obtained in any one of the first to sixth aspects. (1) At the time of cutting, the cut part is turned up by the elasticity of the peeling sheet, and the peeled sheet can be peeled off by picking each piece of the turned up peeling sheet. (2) Since the part where the peeling sheet is divided by elasticity is turned up, the peeling sheet can be easily peeled off simply by pinching the turned up part. (3) Since the peeling sheet is turned up and a part of the plaster is exposed, the exposed part of the plaster is applied to the affected area, and then each piece of the peeled up peeling sheet is pinched and pulled to the left and right. However, it can be stuck to the affected area neatly without trouble, without soiling the hands, and without wrinkling of the patch. (4) The separation of the release sheet is facilitated, and the raw sheet is easily cut at the time of manufacturing, so that convenience and workability are improved. (5) In production, the release sheet can be continuously adhered to the plaster without cutting the release sheet in the middle. (6) Even when the patch is placed in a packaging bag, the yield can be further improved without the release sheet being divided.

[0022]

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS An embodiment of the present invention will be described below with reference to the drawings. (Embodiment 1) FIG. 1 is a perspective view showing a patch using a patch release sheet according to Embodiment 1 of the present invention,
FIG. 2 is a front view of a patch release sheet, and FIG. 3 is a cross-sectional view of a relevant part showing a patch using the patch release sheet. 1 to 3, reference numeral 1 a denotes a patch using the patch release sheet according to the first embodiment of the present invention, 2 denotes an elastic support made of nonwoven fabric or the like, and 3 denotes a surface of the support 2. A plaster made by adding a drug such as methyl salicylate or ketoprofen or water to sodium polyacrylate or the like spread on the entire surface, 4 is a non-stretched polypropylene having a thickness of 10 μm to 75 μm adhered to the entire surface of the plaster 3 In the first embodiment of the present invention, the release sheet for patches in the first embodiment of the present invention, 4a is formed substantially linearly across the substantially central portion of the release sheet for patches 4 and 5a. The cut portion 6 is a connecting portion formed between the cut portions 5a and 5a, and 7a is an embossed portion formed with a rhombic convex portion on substantially the entire surface of the patch release sheet 4. is there. Note that the ratio of the length (a) of the connecting portion 6 to the length (b) of the cut portion 5a is a: b = 1: 8 to 25.
Further, the tensile strength of the patch release sheet 4 having the cuts 5a is 10 g / cm 2 to 140 g / cm.

The method of using the release sheet 4 for a patch according to the present embodiment configured as described above will be described below. FIG. 4 is a side view showing an operation of separating the patch release sheet according to Embodiment 1 of the present invention, and FIG. 5 is a diagram illustrating the operation of separating the patch release sheet according to Embodiment 1 of the present invention to remove the patch. It is a side view which shows the operation | movement which sticks to a. First, as shown in FIG. 4, the both ends of the patch 1 a are pinched, the release sheet 4 for the patch is pulled together with the support 2, and the cut section 5 a is slightly bent, so that the release sheet 4 for the patch is cut into the cut section 5 a. It can be divided right and left along. Also, the separated patch release sheet 4 is turned up from the part separated by the elasticity of the patch release sheet 4 just by slightly bending the cut portion 5a, and the plaster 3 is exposed. Next, as shown in FIG. 5, while applying the exposed plaster 3 to the affected area, the patch 1 a is adhered to the affected area while each piece of the peeled-off adhesive release sheet 4 is pulled left and right to peel off. I do. Thus, the patch 1a can be stuck neatly without soiling the hands and without wrinkling of the patch 1a.

As described above, since the release sheet 4 for a patch of this embodiment is constituted, it has the following effects. 1) Since the release sheet 4 for a patch is made of a material having excellent tensile strength, and the waist is reinforced by the embossed portion 7a, the support 2 is made of a material having an excellent elasticity. By utilizing the difference in the elongation percentage between the release sheet 4 and the support 2, the release sheet 4 for the patch can be obtained simply by holding the both ends of the patch 1 a and pulling the release sheet 4 for the patch together with the support 2 to the left and right. 4 can be cut along the cut 5a, and the cut-off patch release sheet 4 can be turned up by its elasticity to expose the plaster, and the patch 1a can be wrinkled without soiling the hands. It can be stuck to the affected area neatly without rubbing. 2) Simply by rubbing the cut 5a of the patch 1a with one hand with one finger, the frictional resistance of the embossed portion 7a is high and the finger is easily hooked, so that the patch release sheet 4 can be cut cleanly. 3) One of the four separated release sheets for a patch can be turned up and applied to the affected area, and then the other release piece can be applied simply by peeling it off.

Embodiment 2 FIG. 6 is a front view of a release sheet according to Embodiment 2 of the present invention. Reference numeral 4 denotes a patch release sheet, 4a denotes an end portion of the patch release sheet 4, and 6 denotes a connecting portion. These are the same as those in the first embodiment. I do. Embodiment 1
What is different is that a cut portion 5b formed substantially in a wavy line across a substantially central portion of the patch release sheet 4 and a round convex portion are formed on substantially the entire surface of the patch release sheet 4. And an embossed portion 7b. As described above, according to the present embodiment, the patch is easily separated at the cut portion 5b by pulling the patch to the left or right with a slight force or rubbing the embossed portion 7b on the surface of the patch release sheet 4. Since the crests of the peeled-off patch release sheet 4 protrude into protruding pieces, the protruding pieces can be picked up and easily peeled off from the plaster.

(Embodiment 3) FIG. 7 is a front view of a main part of a release sheet according to Embodiment 3 of the present invention. Reference numeral 4 denotes a release sheet, and reference numeral 6 denotes a connecting portion. These are the same as those in the first embodiment.
The difference from the first embodiment is that a cut portion 5c formed in a substantially wavy shape across a substantially central portion of the patch release sheet 4.
And an embossed portion 7c formed to have a triangular projection on substantially the entire surface of the patch release sheet 4.

(Embodiment 4) FIG. 8 is a front view of a main part of a release sheet according to Embodiment 4 of the present invention. Reference numeral 4 denotes a release sheet, and reference numeral 6 denotes a connecting portion. These are the same as those in the first embodiment.
The difference from the first embodiment is that a cut portion 5 d formed in a substantially saw blade shape across a substantially central portion of the patch release sheet 4.
And an embossed portion 7d formed with a star-shaped convex portion on substantially the entire surface of the patch release sheet 4.

(Embodiment 5) FIG. 9 is a perspective view showing a patch using a release sheet according to Embodiment 5 of the present invention. 2 is a support, 3 is a plaster, 4 is a patch release sheet, 4a is an end of the patch release sheet 4, 6 is a connecting portion, and these are the same as in the first to fourth embodiments. Therefore, the same reference numerals are given and the description is omitted. The difference from the first embodiment is that a cut portion 5e formed substantially linearly across the side of one end of the patch release sheet 4.
And embossed portions formed on both sides of the cut portion 5e with diamond-shaped convex portions over a width of 10 to 20 mm.

(Embodiment 6) FIG. 10 is a perspective view showing a patch using a release sheet according to Embodiment 6 of the present invention. 2 is a support, 3 is a plaster, 4 is a patch release sheet, 4a is an end of the patch release sheet 4, 5a is a cut, 6 is a connecting portion, and 7a is an embossed portion. This is the same as the first embodiment, and the same reference numerals are given and the description is omitted. The difference from the first embodiment is that the embossed portion 7a is provided with a display portion 8 in which a peeling position and the like are displayed so as to be easily understood by printing.

[0030]

Embodiments Hereinafter, more specific embodiments will be described. (Example 1) Made of unstretched polypropylene (CPP), stretched polypropylene (OPP), polyethylene terephthalate (PE) having a length of 150 mm, a width of 50 mm and a thickness of 30 μm
A release sheet for a patch manufactured by T) was prepared. Next, a linear cut portion in which the ratio of the length (a) of the connecting portion to the length (b) of the cut portion was a: b = 1: 5 was provided substantially at the center of each release sheet.

Example 2 A release sheet for a patch was prepared in the same manner as in Example 1. Next, a linear cut portion in which the ratio of the length (a) of the connecting portion to the length (b) of the cut portion was a: b = 1: 8 was provided substantially at the center of each release sheet.

Example 3 A release sheet for a patch was prepared in the same manner as in Example 1. Next, a linear cut portion in which the ratio of the length (a) of the connecting portion to the length (b) of the cut portion was a: b = 1: 15 was provided substantially at the center of each release sheet.

(Sensory Test) Each release sheet was pulled and the degree of functionality when torn was examined. The evaluation method, when tearing the cut part of each release sheet, was evaluated as “□” if it felt very easy to cut, “O” if it felt easy to cut, and “×” if it felt hard to cut. . The results are shown in (Table 1).

[0034]

[Table 1]

(Tensile Strength Test) Using a tensile tester (AGS-100B, manufactured by Shimadzu Corporation), the tensile strength of each release sheet having a cut portion was measured. Here, the release sheet was sandwiched by a chuck having a width of 50 mm with a distance between gauge points of 100 mm, pulled at a rate of 100 mm / min, and the load at break was measured. The results are shown in (Table 1).

As is clear from Table 1, the ratio of the length of the connecting portion to the length of the cut portion was determined in Example 3 (a: b = 1: 1).
In the case of 5), it is very easy to divide, and Example 2 (a: b =
1: 8), the separation was easy. However, the ratio of the length of the connecting portion to the length of the cut portion is different from that of the first embodiment.
In the case of (a: b = 1: 5), it was difficult to divide, and a non-cut portion was confirmed in a part. Further, the tensile strength of the release sheet for patches was 40 g / cm to 58 g when the ratio of the length of the connecting portion to the length of the cut portion was Example 3 (a: b = 1: 15).
g / cm, 69 g in Example 2 (a: b = 1: 8)
/ Cm to 98 g / cm, and in the case of Example 1 (a: b = 1: 5), it was 156 g / cm to 187 g / cm.

[0037]

As described above, according to the present invention, the following advantageous effects can be obtained. According to the first aspect of the present invention, (1) Since the cutout portion formed with the connecting portion having a predetermined length is provided on the release sheet, only the release sheet can be easily divided at the cutout portion. (2) At the time of division, the part where the release sheet is divided by elasticity is turned up, so that the release sheet can be peeled off by picking up each piece of the peeled-up release sheet. (3) When each piece of the release sheet is picked, the exposed portion of the plaster can be attached only to the affected part without soiling the hands. (4) Since the peeling sheet is turned up and a part of the plaster is exposed, the exposed part of the plaster is applied to the affected area, and then each piece of the peeled up peeling sheet is pinched and pulled to the left and right. However, it can be stuck to the affected area neatly without trouble, without soiling the hands, and without wrinkling of the patch. (5) By simply pulling the release sheet and the support and the like to the left and right, it is possible to easily separate only the release sheet at the cut portion by utilizing the difference in elongation between the release sheet and the support and the like.

According to the invention described in claim 2, according to claim 1
In addition to the effects of the invention of (1), the embossed portion is formed on the surface of the release sheet, so that when the release sheet is divided or when a patch is manufactured, the embossed portion is formed with a finger or a plaster. The friction resistance with the body can be increased, making it easy to pick the release sheet by hand, or when creating a raw sheet by applying the release sheet on the plaster spread on the support When the raw sheet is cut or the like, the release sheet can be brought into close contact with the plaster, and the release sheet can be prevented from being displaced from the plaster. (2) Since the release sheet is provided with an embossed portion formed on the surface of the release sheet, the release sheet of this patch can be used without the necessity of starting peeling such as searching for a corner of the support with a nail. By simply pulling the sheet together with the support and bending the sheet at the cut, the release sheet alone can be easily cut at the cut. (3) Since the embossed portion is formed on the release sheet, the release sheet can be easily and smoothly released without slipping during the release operation. (4) Since the embossed portion is formed on the release sheet, when manufacturing the patch, when the release sheet is laminated on the plaster spread on one surface of the support, the release sheet is placed on the plaster. Lamination can be performed without slippage. (5) When the raw sheet is cut because the frictional resistance of the embossed portion is large, the raw sheet is prevented from being entangled in the cut edge cutting tool, and the release sheet does not slip, thereby improving the productivity. . (6) Even when air bubbles are generated between the plaster body and the plaster body and the release sheet, the air bubbles can be easily discharged by the embossed portion, so that the product yield can be drastically improved. .

According to the invention described in claim 3, according to claim 1
In addition to the effects of the invention of (2), (1) since the connecting portion and the cut portion are formed at a predetermined interval, the medicinal component does not volatilize and the medicinal effect does not decrease, and the reliability and convenience are excellent. (2) Since the connecting portion and the cut portion are formed at a predetermined interval, the separation sheet can be easily separated, the raw sheet can be easily cut at the time of manufacturing, and convenience and workability are improved.

According to the invention of claim 4, in addition to the effect of the invention of any one of claims 1 to 3, (1) the cut portion has an S-shape, a wave shape, a saw blade shape or the like. In this case, the protruding pieces protrude from one surface of the separated release sheet, so that the protruding pieces can be easily picked up and easily peeled off. (2) If the cut portion is formed in an S-shape, a wave shape, a saw blade shape, or the like, when the release sheet is cut, the protruding portion protrudes in a cross section. Can be easily peeled off.

According to the fifth aspect of the present invention, in addition to the effects of the first aspect of the present invention, (1) at the time of production, the release sheet is continuously cut without cutting in the middle. The release sheet can be stuck on the plaster. (2) Even when the patch is placed in the packaging bag, the yield can be further improved without the release sheet being divided.

According to the invention described in claim 6, in addition to the effects of the invention described in any one of claims 1 to 5, (1) the release sheet is not entangled with the plaster at the time of release,
The release sheet can be easily pinched and peeled. (2) The workability and the like are improved without the release sheet being immediately cut off during production. (3) When the release sheet is attached on the plaster, the release sheet can be attached neatly without wrinkles. (4) The raw sheet can be easily cut at the time of manufacturing, and workability and the like are improved.

According to the seventh aspect of the present invention, in addition to the effects of the first aspect of the present invention, (1) at the time of division, the divided part is turned up by the elasticity of the release sheet. The release sheet can be peeled off by picking up each piece of the release sheet that has risen and turned up. (2) Since the part where the peeling sheet is divided by elasticity is turned up, the peeling sheet can be easily peeled off simply by pinching the turned up part. (3) Since the peeling sheet is turned up and a part of the plaster is exposed, the exposed part of the plaster is applied to the affected area, and then each piece of the peeled up peeling sheet is pinched and pulled to the left and right. However, it can be stuck to the affected area neatly without trouble, without soiling the hands, and without wrinkling of the patch. (4) The separation of the release sheet is facilitated, and the raw sheet is easily cut at the time of manufacturing, so that convenience and workability are improved. (5) In production, the release sheet can be continuously adhered to the plaster without cutting the release sheet in the middle. (6) Even when the patch is placed in a packaging bag, the yield can be further improved without the release sheet being divided.

[Brief description of the drawings]

FIG. 1 is a perspective view showing a patch using a patch release sheet according to Embodiment 1 of the present invention.

FIG. 2 is a front view of the patch release sheet according to Embodiment 1 of the present invention.

FIG. 3 is a cross-sectional view of a relevant part showing a patch using the patch release sheet according to Embodiment 1 of the present invention;

FIG. 4 is a side view showing an operation of cutting the release sheet for a patch in Embodiment 1 of the present invention.

FIG. 5 is a side view showing an operation of peeling off the release sheet for a patch and adhering the patch to an affected part according to the first embodiment of the present invention;

FIG. 6 is a front view of a release sheet for a patch in Embodiment 2 of the present invention.

FIG. 7 is a front view of an essential part of a release sheet for a patch in Embodiment 3 of the present invention.

FIG. 8 is a main part front view of the release sheet for a patch in Embodiment 4 of the present invention.

FIG. 9 is a perspective view showing a patch using the patch release sheet according to the fifth embodiment of the present invention.

FIG. 10 is a perspective view showing a patch using the patch release sheet according to Embodiment 6 of the present invention.

FIG. 11 is a perspective view showing a patch using a conventional patch release sheet.

[Explanation of symbols]

 1a, 1b, 1c, 1d, 1e, 1f, 11 Patch 2,12 Support 3,13 Patch 4,14 Release Sheet 4a End of Release Sheet 5a, 5b, 5c, 5d, 5e Cut 6 Connection 7a, 7b, 7c, 7d, 7e Embossed part 8 Display part

Claims (7)

[Claims] 1. A release sheet for a patch, which has cuts formed at predetermined intervals. 2. The release sheet for a patch according to claim 1, wherein the release sheet has an embossed portion. 3. The cut portion is formed such that the ratio of the length of the connecting portion (a) formed between the cut portions and the length of the cut portion (b) is a: b = 1: 5 to 25. The release sheet for a patch according to claim 1 or 2, wherein 4. The cut portion is formed in a linear shape, an S shape, a wave shape, or a saw blade shape.
4. The release sheet for a patch according to any one of items 1 to 3. 5. The tensile strength of the release sheet having the cuts formed therein is from 10 g / cm to 140 g / cm.
5. The method according to claim 1, wherein
3. The release sheet for a patch according to item 1. 6. The release sheet having a thickness of 10 μm or less.
The patch release sheet according to any one of claims 1 to 5, wherein the thickness is 75 µm. 7. The release sheet may be a film or sheet of unstretched or stretched polypropylene, polyethylene terephthalate, polyethylene, polyvinyl chloride, polyester, polyvinylidene chloride, polyester, or polystyrene synthetic resin, or siliconized paper or aluminum foil. The release sheet for a patch according to any one of claims 1 to 6, which is selected.