JP3566960B2 - Patch - Google Patents
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- Publication number
- JP3566960B2 JP3566960B2 JP2003316093A JP2003316093A JP3566960B2 JP 3566960 B2 JP3566960 B2 JP 3566960B2 JP 2003316093 A JP2003316093 A JP 2003316093A JP 2003316093 A JP2003316093 A JP 2003316093A JP 3566960 B2 JP3566960 B2 JP 3566960B2
- Authority
- JP
- Japan
- Prior art keywords
- release sheet
- plaster
- patch
- cut
- support
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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Description
本発明は、パップ剤や硬膏剤等の貼付剤に関する。更に詳しくは、高齢者でも簡単に手を汚すことなく、またパップ剤や硬膏剤等の貼付剤にシワがよったりすることなくきれいに患部に貼着することができる利便性に優れたパップ剤や硬膏剤等の貼付剤に関するものである。 The present invention relates to a patch such as a poultice or a plaster. More specifically, even for elderly people, a convenient cataplasm that can be easily and easily stained on the affected area without fouling the hands, and without wrinkling of patches such as cataplasms and plasters. it relates to the adhesive patch such as plasters.
近年、高齢化社会が進むと共に、事務の合理化で各種コンピュータが利用されその結果、腰や肩、膝、肘等に痛みを訴える人が増加する傾向にあり、その対症療法として湿布剤や硬膏剤等が広く利用されている。
以下に従来のパップ剤や硬膏剤等の貼付剤について、図面を参照しながら説明する。
図１１は従来のパップ剤や硬膏剤等の貼付剤を示す斜視図である。図１１において、１１は従来のパップ剤や硬膏剤等の貼付剤、１２は白色や肌色の不織布等からなる支持体、１３は支持体１２の一面の略全面に展着された薬物等が含有された膏体、１４は膏体１３の全面に貼着された極めて薄い柔軟性を有する透明な合成樹脂フィルム等からなる剥離シートである。
以上のように構成された従来のパップ剤や硬膏剤等の貼付剤について、以下その使用方法を説明する。図１１に示すように、まず、支持体１２の隅部を何度も爪で探って膏体１３と剥離シート１４とが剥がれやすいようにした後、剥離シート１４を爪で剥ぎ、次いで、支持体１２がよじれてシップ膏体同士が絡みつかないように注意しながら剥離シート１４を剥離した後、支持体１２を持って患部に貼付して用いられていた。
また、（特許文献１）のように、剥離シートに切断部や切れ目部を設け、この切断部や切れ目部より剥離を行うようにした貼付剤も開示されている。また、膏体より大面積の剥離シートを用いたもの、２枚の剥離シートを膏体の略中央部分で重ね合わせ、この膏体に接触しない重ね合わせ部分より剥離を行うようにしたもの等が提案されている。
Hereinafter, conventional patches such as cataplasms and plasters will be described with reference to the drawings.
FIG. 11 is a perspective view showing a conventional patch such as a poultice or plaster. In FIG. 11, 11 is a patch such as a conventional poultice or plaster, 12 is a support made of a white or flesh-colored nonwoven fabric, and 13 contains a drug spread on substantially the entire surface of one side of the
The following describes how to use the conventional patches, such as cataplasms and plasters, configured as described above. As shown in FIG. 11, first, the corners of the
Further, as in (Patent Document 1), a patch is also disclosed in which a cut portion or a cut portion is provided on a release sheet, and peeling is performed from the cut portion or the cut portion. In addition, there is a method using a release sheet having a larger area than the plaster, a method in which two release sheets are superimposed at a substantially central portion of the plaster, and a release is performed from a superimposed portion not in contact with the plaster. Proposed.
しかしながら上記従来のパップ剤や硬膏剤等の貼付剤では、以下のような課題を有していた。すなわち、
（１）パップ剤や硬膏剤等の貼付剤が、支持体の一面の略全面に膏体を展着した後、この膏体の上面に剥離シートを貼着して得られた原反シートを角形状等に裁断して形成されるため、支持体や膏体，剥離シートの外周断面が、同一面化されているので、剥離シートを外側縁から剥がす際、剥がし始める手掛かりがなく、爪先を剥離シートの先端にかけてもうまく掛からず、剥離作業が困難で使用し難いという問題点を有していた。
（２）膏体には、皮膚等への増粘作用を付与するために増粘剤が含有されているため、膏体の粘着性が極めて強く、剥離シートが剥離し難いという問題点を有していた。
（３）湿布剤や硬膏剤等の殆どが、例えば、白色の支持体並びにこの支持体上に貼着された白色又は白色透明の膏体の表面に、極めて薄くて柔軟な剥離シートで覆っているため、剥離シートと膏体の区別がつき難く剥離位置が不明確なため、剥離シートが摘み難いという問題点を有していた。
（４）このため、患者がいざ患部に貼ろうとしても、剥離シートが剥ぎ取り難く剥離シートを剥ぎ取ることにいたずらに時間を浪費し、イライラすることも多く、剥離作業が困難で、使用上大変不便であるという問題点を有していた。
（５）特に、高齢者にとっては、指先が器用ではなく、しかも視力等も低下していることから、薄肉透明の剥離シートが膏体と同色化しかつ密着しているため、剥離が困難で膏体から剥離シートを剥ぎ取ることは大きな負担を強いるという問題点を有していた。
（６）また、剥離シートも支持体も共に柔軟なため支持体がよじれて膏体同士が絡み付き使用できないという問題点も有していた。
（７）（特許文献１）の剥離シートに切断部が設けられたものは、使用時以外に、剥離シートがこの切断部からめくれてしまい、このめくれた部分から膏体に含有された薬効成分が揮発してしまい、薬効効果が得られないという問題点を有していた。
（８）また、剥離シートに切れ目部が設けられたものでは、剥離シートの材質や切れ目部の間隔によっては剥離シートをきれいに分断することが困難という問題点を有していた。
（９）剥離シートが膏体よりも大きな面積で形成されている場合は、大面積の剥離シートを必要とするため、コストが高くなり、また、このパップ剤や硬膏剤等の貼付剤を製造する場合、原反シートを裁断した後、更にパップ剤や硬膏剤等の貼付剤の外縁部の支持体や膏体を切除する作業が必要で、作業性に欠けるとともにその分生産性に劣るという問題点を有していた。
（１０）２枚の剥離シートを膏体の略中央部分で重ね合わせた場合は、多大の生産工数を要すと共に作業性に欠け製品得率を下げ生産性に欠けるという問題点を有していた。
（１１）更に、パップ剤や硬膏剤等の貼付剤に使用される剥離シートは、通常凹凸等がなく形成されているものが多く、剥離シートを摘んだときすべり易く、剥離がし難いという問題点を有していた。
（１２）また、パップ剤や硬膏剤等の貼付剤の製造時に、膏体上に剥離シートを貼着しようとしてもすべってうまく貼着できず、また裁断しようとしても裁断機に巻き込まれ、膏体上からずれ易く、製品得率が低いという問題点を有していた。
（１３）更に、膏体やこの膏体と剥離シートの間に気泡を生じ易く、歩留りが低下するという問題点を有していた。
However, the conventional patches such as cataplasms and plasters have the following problems. That is,
(1) After a patch such as a poultice or plaster spreads a plaster on substantially the entire surface of the support, a raw sheet obtained by sticking a release sheet on the upper surface of the plaster is used. Since it is formed by cutting into a square shape, the outer peripheral cross-sections of the support, the plaster, and the release sheet are flush with each other, so there is no clue to start peeling when peeling the release sheet from the outer edge. There was a problem that even if it was applied to the tip of the release sheet, it did not work well, and the peeling operation was difficult and difficult to use.
(2) Since the paste contains a thickening agent to impart a thickening effect to the skin and the like, there is a problem that the paste is extremely strong and the release sheet is difficult to peel. Was.
(3) Most of poultices, plasters and the like are covered with, for example, a very thin and flexible release sheet on the surface of a white support and a white or white transparent plaster stuck on the support. Therefore, there is a problem that it is difficult to distinguish the release sheet from the plaster and the release position is unclear, so that the release sheet is difficult to pick.
(4) For this reason, even if the patient tries to stick to the affected area, the peeling sheet is difficult to peel off, and time is wasted unnecessarily to peel off the peeling sheet. There was a problem that it was very inconvenient.
(5) Particularly, for elderly people, the fingertips are not dexterous and their visual acuity and the like are deteriorated. Therefore, the thin transparent release sheet has the same color as the plaster and is in close contact with the plaster. Peeling off the release sheet from the body has a problem that a great burden is imposed.
(6) In addition, since both the release sheet and the support are flexible, the support is kinked and the plasters are entangled with each other and cannot be used.
(7) When the release sheet of (Patent Document 1) is provided with a cut portion, the release sheet is turned up from the cut portion except during use, and the medicinal ingredient contained in the plaster from the turned up portion Has volatilized, and a medicinal effect cannot be obtained.
(8) Further, in the case where a cut portion is provided in the release sheet, there is a problem that it is difficult to divide the release sheet neatly depending on the material of the release sheet and the interval between the cut portions.
(9) If the release sheet is formed with a larger area than the plaster, a large area of the release sheet is required, which increases the cost and manufactures a patch such as a cataplasm or plaster. In this case, after cutting the raw sheet, it is necessary to further cut off the support and plaster at the outer edge of the patch such as a cataplasm or plaster, resulting in poor workability and poor productivity by that amount. Had problems.
(10) When two release sheets are superimposed at a substantially central portion of the plaster, there is a problem that a large number of production steps are required, workability is reduced, product yield is reduced, and productivity is reduced. Was.
(11) Furthermore, release sheets used for patches such as cataplasms and plasters are usually formed without any irregularities and the like, so that when the release sheet is picked, it is easy to slip and is difficult to peel. Had a point.
(12) In addition, when manufacturing a patch such as a cataplasm or a plaster, the release sheet is not properly adhered to the plaster even if it is to be pasted on the plaster. There was a problem that the product was easily displaced from the body and the product yield was low.
(13) Further, there is a problem that air bubbles are easily generated between the paste and the paste and the release sheet, and the yield is reduced.
本発明は上記従来の問題点を解決するもので、パップ剤や硬膏剤等の貼付剤を左右に引張るだけで剥離シートを簡単に分断でき、剥離シートのめくれた部分を患部に貼着するだけで、高齢者でも簡単に手を汚すことなく、かつシワがよったりすることなくきれいに貼着することができる低原価で量産性に適したパップ剤や硬膏剤等の貼付剤の使用方法を提供することを目的とする。 The present invention solves the above-mentioned conventional problems, in which the release sheet can be easily divided simply by pulling a patch such as a cataplasm or a plaster to the left and right, and the rolled-up portion of the release sheet is simply adhered to the affected part. Provides a low-cost, mass-productive and suitable method of using patches such as cataplasms and plasters that can be easily adhered to the elderly without soiling their hands and without wrinkling. The purpose is to do.
上記従来の課題を解決するために本発明の貼付剤は、以下の構成を有している。
本発明の貼付剤は、伸縮性を有する支持体と、該支持体の一面の略全面に展着された膏体と、該膏体の全面に貼着されたエンボス加工部が形成された、前記支持体の伸び率とは異なる伸び率を有する１枚の剥離シートとを備えた貼付剤であって、該貼付剤の両端部を持って左右に引張ることにより、前記剥離シートのみが切れ目部で分断される構成を有している。
これにより、以下のような作用を有する。
（１）剥離シートと支持体等を左右に引張るだけで、剥離シートと支持体等との伸び率の違いを利用して、剥離シートのみを切れ目部で分断できる。
（２）分断時、剥離シートが弾性により分断された部位がめくれ上がるので、そのめくれ上がった剥離シートの各片を摘み取ることで、剥離シートを容易に剥ぎ取ることができる。
（３）剥離シートの各片を摘んだ際、膏体の露出した部分を患部に貼着するだけで手を汚すことなく貼着することができる。
（４）剥離シートがめくれ、膏体の一部が露出されるので、この膏体の露出部を患部にあて、次いで、めくれた剥離シートの各片をつまんで左右に引張るだけで、高齢者でも手間をかけずに、また手を汚すことなく、更にパップ剤や硬膏剤等の貼付剤にシワがよったりすることなくきれいに患部に貼着することができる。
（５）剥離シートの表面にエンボス加工部が形成されていることにより、剥離シートを分断するときや、パップ剤や硬膏剤等の貼付剤を製造するとき等、このエンボス加工部が指や膏体との摩擦抵抗を大とすることができ、剥離シートを手で摘み易くしたり、支持体上に展着された膏体上に剥離シートを貼着して原反シートを作成するときやこの原反シートを裁断するとき等、剥離シートを膏体上に密着させることができ、剥離シートが膏体からずれること等が防止できる。
（６）剥離シートが、剥離シートの表面に形成されたエンボス加工部を備えたので、支持体の隅部を爪で探る等の剥離開始作業を要することなく、ただこのパップ剤や硬膏剤等の貼付剤の剥離シートを支持体等とともに外側に引張るだけで、容易に剥離シートのみを分断することができる。
（７）剥離シートにエンボス加工部が形成されているので、剥離作業の際に滑ったりすることがなく、剥離シートの剥離を簡単にかつ円滑に行うことができる。
（８）剥離シートにエンボス加工部が形成されているので、パップ剤や硬膏剤等の貼付剤を製造するに際して、支持体の一面に展着された膏体上に剥離シートを積層する場合、剥離シートが膏体上を滑ってずれることがなく積層することができる。
（９）エンボス加工部の摩擦抵抗が大きいので原反シートを裁断する場合、刃具に原反シートが巻き込まれるのを防止し剥離シートがずれ込むことがなく、生産性を向上させることができる。
（１０）膏体やこの膏体と剥離シートの間に気泡が生じた場合も、この気泡をエンボス加工部によって容易に排出することができるので、製品歩留りを飛躍的に向上させることができる。
In order to solve the above-mentioned conventional problems, the patch of the present invention has the following constitution.
Paste agent of the invention comprises a support having elasticity, a plaster which is spreadable over substantially the entire surface of one side of the support, the embossed portion adhered to the entire surface of the plaster is formed , a patch that includes a single release sheet having a different elongation from the elongation of the support, by pulling the right and left with the two end portions of the patch, only the release sheet is cut It is configured to be divided by a part .
This has the following effects.
(1) Just by pulling the release sheet and the support and the like to the left and right, only the release sheet can be divided at the cut portion by utilizing the difference in the elongation rate between the release sheet and the support and the like.
(2) At the time of division, the part where the release sheet is divided by elasticity is turned up, so that the release sheet can be easily peeled off by picking each piece of the peeled-off release sheet.
(3) When each piece of the release sheet is picked, the exposed portion of the plaster can be attached only to the affected part without soiling the hands.
(4) Since the peeling sheet is turned up and a part of the plaster is exposed, the exposed part of the plaster is applied to the affected area, and then, each piece of the peeled-off peeling sheet is pinched and pulled left and right. However, it can be stuck to the affected part neatly without trouble, without soiling the hands, and without wrinkling on patches such as cataplasms and plasters.
(5) Since the embossed portion is formed on the surface of the release sheet, the embossed portion is formed with a finger or a plaster when dividing the release sheet or manufacturing a patch such as a poultice or plaster. It is possible to increase the frictional resistance with the body, make it easy to pick the release sheet by hand, or when creating a raw sheet by sticking the release sheet on the plaster spread on the support When the raw sheet is cut or the like, the release sheet can be brought into close contact with the plaster, and the release sheet can be prevented from being displaced from the plaster.
(6) Since the release sheet is provided with an embossed portion formed on the surface of the release sheet, there is no need to perform a peeling start operation such as searching for a corner of the support with a nail, and the pulp or plaster is simply used. By simply pulling the release sheet of the patch together with the support and the like outward, only the release sheet can be easily divided.
(7) Since the embossed portion is formed on the release sheet, the release sheet can be easily and smoothly released without slipping during the release operation.
(8) Since an embossed portion is formed on the release sheet, when manufacturing a patch such as a poultice or plaster, when a release sheet is laminated on a plaster spread on one surface of a support, The release sheet can be laminated without slipping on the plaster.
(9) When the raw sheet is cut because the frictional resistance of the embossed portion is large, it is possible to prevent the raw sheet from being caught in the cutting tool, prevent the release sheet from slipping, and improve the productivity.
(10) Even when air bubbles are generated between the plaster or the plaster and the release sheet, the air bubbles can be easily discharged by the embossed portion, so that the product yield can be significantly improved.
ここで、剥離シートとしては、無延伸ポリプロピレン（ＣＰＰ），延伸ポリプロピレン（ＯＰＰ），ポリエチレンテレフタレート（ＰＥＴ），ポリブチレンテレフタレート（ＰＢＴ），ポリエチレン，ポリエステル，ポリウレタン，ポリ塩化ビニル，ポリスチレン等のプラスチックフィルム，合成樹脂や合成紙，合成繊維等にシリコン加工したシリコン加工紙，アルミ箔，クラフト紙にポリエチレン等をラミネートしたラミネート加工紙等の無色又は着色したものが用いられる。
剥離シートの引張り強度は、１０ｇ／cm〜１４０ｇ／cm，好ましくは２０ｇ／cm〜１００ｇ／cm，更に好ましくは３０ｇ／cm〜６０ｇ／cmの範囲とするのが好ましい。剥離シートの引張り強度が３０ｇ／cmより小さくなるにつれ製造に際して、剥離シートが途中で切断してしまい、連続して膏体上に剥離シートを貼着することができなくなり、またパップ剤や硬膏剤等の貼付剤を包装袋の中に入れる場合にも、容易に剥離シートが分断され、更に歩留りが低下する傾向が現れやすいので好ましくない。引張り強度が６０ｇ／cmより大きくなるにつれ使用するに際して容易に剥離シートを分断することが困難となり、利便性が低下する傾向が現れだすので好ましくない。
Here, as the release sheet, plastic films such as unstretched polypropylene (CPP), stretched polypropylene (OPP), polyethylene terephthalate (PET), polybutylene terephthalate (PBT), polyethylene, polyester, polyurethane, polyvinyl chloride, and polystyrene; Colorless or colored materials such as synthetic resin, synthetic paper, silicon processed paper obtained by processing silicon into synthetic fibers, aluminum foil, and laminated paper obtained by laminating kraft paper with polyethylene or the like are used.
The tensile strength of the release sheet is preferably in the range of 10 g / cm to 140 g / cm, preferably 20 g / cm to 100 g / cm, more preferably 30 g / cm to 60 g / cm. As the tensile strength of the release sheet becomes smaller than 30 g / cm, during the production, the release sheet is cut in the middle, making it impossible to continuously adhere the release sheet on the plaster, Also, when a patch such as is put in a packaging bag, the release sheet is easily cut off, and the yield tends to decrease, which is not preferable. As the tensile strength exceeds 60 g / cm, it becomes difficult to easily separate the release sheet when used, and the convenience tends to decrease, which is not preferable.
剥離シートの厚みは１０μｍ〜７５μｍ，好ましくは１２μｍ〜４０μｍ，更に好ましくは１５μｍ〜３５μｍの範囲で形成されるのが好ましい。剥離シートの厚みが１５μｍより小さくなるにつれ、剥離シートが薄くなり過ぎて剥離に際して剥離シートが膏体に絡んだり、また剥離シートが薄くて滑り易いため摘みにくかったり、更に、製造に際して剥離シートが直ぐに分断されてしまい、作業性等が低下したり、また、膏体上に剥離シートを貼着する場合、剥離シートに皺が寄り易くなる傾向が現れだし、好ましくない。また、 剥離シートの厚みが３５μｍより大きくなるにつれ剥離等に際して剥離シートが摘み易くなるものの、分断が困難となり、また、製造に際して原反シートを切断することが困難となり、作業性等が低下する傾向が現れだし、好ましくない。
また、剥離シートの左右部分に引き裂き方法を明確にするため、矢印等の図形や文字，記号等の表示部を設けてもよく、また、着色等してもよい。
The thickness of the release sheet is preferably in the range of 10 μm to 75 μm, preferably 12 μm to 40 μm, and more preferably 15 μm to 35 μm. As the thickness of the release sheet becomes smaller than 15 μm, the release sheet becomes too thin and the release sheet becomes entangled with the plaster when peeling off, or the release sheet is thin and slippery, so it is difficult to pick up, and further, the release sheet immediately If the release sheet is stuck on the plaster, the wrinkle tends to appear on the release sheet, which is not preferable. In addition, as the thickness of the release sheet becomes larger than 35 μm, the release sheet becomes easy to be gripped at the time of peeling or the like, but it becomes difficult to cut the sheet, and it becomes difficult to cut the raw sheet at the time of manufacturing, and the workability and the like tend to decrease. Appears and is not preferred.
Further, in order to clarify the tearing method on the left and right portions of the release sheet, a display portion such as a figure such as an arrow, a character, a symbol, or the like may be provided, or coloring may be performed.
エンボス加工部としては、剥離シートの全面または局部的な箇所、例えば切れ目部を引き裂く際に手で摘み易い箇所、例えば切れ目部の両側部に１０〜２０mmや、引き裂いた剥離シートを剥離する際に摘み易い箇所等に形成される。
エンボス加工部の形状は、特に限定されるものではないが、滑ることなく手で摘み易くするものであれば、例えば、格子状，丸形状，角形状，星形状等その他種々の形状に形成されてもよい。
As the embossed portion, the entire surface or a local portion of the release sheet, for example, a portion that is easy to be picked by hand when tearing the cut portion, for example, 10 to 20 mm on both sides of the cut portion, and when peeling the torn release sheet It is formed at a place that is easy to pick.
The shape of the embossed portion is not particularly limited, but may be formed into various shapes such as a lattice shape, a round shape, a square shape, a star shape, and the like, as long as it can be easily picked by hand without slipping. You may.
支持体としては、織布，編布，不織布，不織紙等の伸縮性のもの等が挙げられる。支持体に伸縮性のものを用いた場合は、支持体と剥離シートの伸び率等の差を利用して、支持体と共に剥離シートを引張るだけで、容易に剥離シートを分断して、剥離シートを膏体から剥がすことができる。
なお、この伸縮性の支持体は縦方向及び／又は横方向に１０〜１００％の伸縮率を有することが望ましい。これにより、支持体と剥離シートの伸び率等の差を利用して、支持体と共に剥離シートを引張るだけで、容易に剥離シートを分断して、剥離シートを膏体から剥がすことができる。
Examples of the support include stretchable materials such as woven fabric, knitted fabric, nonwoven fabric, and nonwoven paper. When a stretchable support is used, the release sheet can be easily divided by simply pulling the release sheet together with the support by utilizing the difference in elongation between the support and the release sheet. Can be peeled from the plaster.
The stretchable support preferably has a stretch rate of 10 to 100% in the vertical direction and / or the horizontal direction. This makes it possible to easily divide the release sheet and peel the release sheet from the plaster simply by pulling the release sheet together with the support, utilizing the difference in elongation percentage between the support and the release sheet.
これらの支持体の具体的な材料としては、紙，綿，大麻，黄麻等の靱皮繊維，マニラ麻等の葉脈繊維等のセルロース繊維、羊毛等の獣毛繊維や，絹繊維，羽毛繊維等のタンパク繊維等の天然繊維、レーヨン，キュプラ等の再生セルロース繊維や再生タンパク繊維等の再生繊維、酢酸セルロース繊維やプロミックス等の半合成繊維、ナイロンアラミド繊維，ポリエチレンテレフタレート繊維，ポリエステル繊維，アクリル繊維等，ポリエチレンやポリプロピレン等のポリオレフィン繊維，ポリビニルアルコール繊維，ポリ塩化ビニル繊維，ポリ塩化ビニリデン繊維，ポリ塩化ビニル系繊維，ポリウレタン繊維，ポリオキシメチレン繊維，ポリテトラフルオロエチレン繊維，ポリパラフェニレンベンズビスチアゾール（ＰＢＴ）繊維、ポリイミド繊維等が利用できる。
支持体は、厚さ，伸び，引張り強さ，作業性などの物理的性質や貼付時の感触、患部の密閉性，薬物の支持体への移行等を考慮して選択される。
Specific materials for these supports include paper, cotton, bast fibers such as hemp, jute, cellulose fiber such as leaf vein fiber such as manila hemp, animal hair fiber such as wool, and protein such as silk fiber and feather fiber. Natural fiber such as fiber, regenerated cellulose fiber such as rayon and cupra, regenerated fiber such as regenerated protein fiber, semi-synthetic fiber such as cellulose acetate fiber and promix, nylon aramid fiber, polyethylene terephthalate fiber, polyester fiber, acrylic fiber, etc. Polyolefin fiber such as polyethylene and polypropylene, polyvinyl alcohol fiber, polyvinyl chloride fiber, polyvinylidene chloride fiber, polyvinyl chloride fiber, polyurethane fiber, polyoxymethylene fiber, polytetrafluoroethylene fiber, polyparaphenylenebenzbisthiazole (PBT) ) Fiber, polyimide維等 are available.
The support is selected in consideration of physical properties such as thickness, elongation, tensile strength, workability, feel at the time of application, hermeticity of the affected area, transfer of the drug to the support, and the like.
膏体は、基材に薬物を含有または付着等させることにより、外用のパップ剤や硬膏剤等の貼付剤として有効に利用させるものである。膏体は、皮膚への薬効効果が十分得られるように水分を含有し、かつ粘着性を有し、常温又はそれ以上の温度においても軟化し膏体が皮膚に残らない適度な凝集性を有するように形成される。 The plaster is used effectively as a patch such as an external poultice or plaster by containing or adhering a drug to a base material. The plaster contains water so that a sufficient medicinal effect on the skin can be obtained, and has an adhesive property, and has an appropriate cohesive property such that the plaster softens even at room temperature or higher and the plaster does not remain on the skin. It is formed as follows.
増粘剤としては、水分を３０％〜８０％安定に保持でき、かつ保水性を有することが望ましい。この具体例としては、グァーガム，ローカストビーンガム，カラギーナン，アルギン酸，アルギン酸ナトリウム，寒天，アラビアガム，トラガカントガム，カラヤガム，ペクチン，澱粉等の植物系，ザンサンガム，アカシアガム等の微生物系，ゼラチン，コラーゲン等の動物系等の天然高分子，メチルセルロース，エチルセルロース，ヒドロキシエチルセルロース，カルボキシメチルセルロースナトリウム等のセルロース系，可溶性デンプン，カルボキシメチルデンプン，ジアルデヒドデンプン等のデンプン系等の半合成高分子，ポリビニルアルコール，ポリビニルピロリドン，ポリビニルメタクリレート等のビニル系，ポリアクリル酸，ポリアクリル酸ナトリウム等のアクリル系，その他ポリエチレンオキサイド，メチルビニルエーテル／無水マイレン酸共重合体等の合成高分子等の水溶性高分子等が好適に用いられる。特に、ポリアクリル酸ナトリウムが好ましい。ゲル強度が強く、かつ保水性に優れるからである。更に、平均重合度２００００〜７００００のポリアクリル酸ナトリウムが好ましい。平均重合度が２００００より小さくなるにつれ増粘効果が乏しくなり十分なゲル強度が得られなくなる傾向が現れだし、平均重合度が７００００より大きくなるにつれ増粘効果が強すぎ作業性が低下する傾向が現れだし、いずれも好ましくない。また、前記水溶性高分子を２種類以上併用することにより、例えば、ポリアクリル酸ナトリウムの強イオン高分子と高分子コンプレックスを形成し、より一層ゲル強度の大きい弾性ゲルを得ることができる。 As the thickener, it is desirable to be able to stably hold water at 30% to 80% and to have water retention. Specific examples include plant systems such as guar gum, locust bean gum, carrageenan, alginic acid, sodium alginate, agar, arabic gum, tragacanth gum, karaya gum, pectin, starch, etc., microbial systems such as xanthan gum, acacia gum, gelatin, collagen and the like. Natural polymers such as animal-based, cellulose-based such as methylcellulose, ethylcellulose, hydroxyethylcellulose, sodium carboxymethylcellulose, semi-synthetic polymers such as starch-based such as soluble starch, carboxymethylstarch, and dialdehyde starch; polyvinyl alcohol; polyvinylpyrrolidone; Vinyl-based such as polyvinyl methacrylate, acrylic-based such as polyacrylic acid and sodium polyacrylate, other polyethylene oxide, methyl vinyl ether / Water-soluble polymers of a synthetic polymer such as water maleic acid copolymers and the like are suitably used. Particularly, sodium polyacrylate is preferred. This is because the gel strength is high and the water retention is excellent. Further, sodium polyacrylate having an average degree of polymerization of 20,000 to 70,000 is preferred. As the average degree of polymerization becomes smaller than 20,000, the thickening effect becomes poor and sufficient gel strength cannot be obtained. As the average degree of polymerization becomes larger than 70,000, the thickening effect becomes too strong and the workability tends to be reduced. Appears, none of which is desirable. In addition, by using two or more of the above water-soluble polymers, for example, a polymer complex is formed with a strong ionic polymer of sodium polyacrylate, and an elastic gel having higher gel strength can be obtained.
湿潤剤として、グリセリン，プロピレングリコール，ソルビトール等の多価アルコール等や、充填剤として、カオリン，酸化亜鉛，タルク，チタン，ベントナイト，珪酸アルミニウム，酸化チタン，酸化亜鉛，メタ珪酸アルミニウム，硫酸カルシウム，リン酸カルシウム等を添加してもい。また、溶解補助剤または吸収促進剤として、炭酸プロピレン，クロタミトン，ｌ−メントール，ハッカ油，リモネン，ジイソプロピルアジペート等や、薬効補助剤として、サリチル酸メチル，サリチル酸グリコール，ｌ−メントール，チモール，ハッカ油，ノニル酸ワニリルアミド，トウガラシエキス等を添加してもよい。更に、必要に応じて、安定化剤や抗酸化剤、乳化剤等を添加してもよい。
その他必要に応じて、架橋剤や重合剤等を添加してもよい。膏体を強固にするとともに保水性を持たせることができる。この架橋剤や重合剤は、増粘剤等の種類に応じて適宜選択される。例えば、増粘剤にポリアクリル酸またはポリアクリル酸塩を適用した場合は、分子中に少なくとも２個のエポキシ基を有する化合物、Ｃａ，Ｍｇ，Ａｌ等の塩酸塩，硫酸塩，リン酸塩，炭酸塩等の無機酸塩，クエン酸塩，酒石酸塩，グルコン酸塩，ステアリン酸塩等の有機酸塩，酸化亜鉛，無水珪酸等の酸化物，水酸化アルミニウム，水酸化マグネシウム等の水酸化物等の多価金属化合物等が好適に用いられる。また、増粘剤にポリビニルアルコールを適用した場合は、アジピン酸，チオグリコール酸，エポキシ化合物（エピクロルヒドリン），アルデヒド類，Ｎ−メチロール化合物，Ａｌ，Ｔｉ，Ｚｒ，Ｓｎ，Ｖ，Ｃｕ，Ｂ，Ｃｒ等の化合物等の錯化物等が好適に用いられる。また、増粘剤にポリビニルピロリドンを適用した場合は、メチルビニルエーテル／無水マレイン酸共重合体，ポリアシッド化合物またはそのアルカリ金属塩（ポリアクリル酸やタンニン酸およびその誘導体）等が好適に用いられる。また、増粘剤にポリエチレンオキサイドを適用した場合は、パーキオサイド，ポリスルホンアザイド等が好適に用いられる。また、増粘剤にメチルビニルエーテル／無水マレイン酸共重合体を適用した場合は、多官能ヒドロキシ化合物，ポリアミン，ヨウ素，ゼラチン，ポリビニルピロリドン，鉄，水銀，鉛塩等が好適に用いられる。増粘剤にゼラチンを適用した場合は、ホルムアルデヒド，グルタルアルデヒド，ジアルデヒドデンプン等のアルデヒド類、グリオキサール、ブタジエンオキシド等のジエポキシド類、ジビニルケトン等のジケトン類、ジイソシアネート類等が好適に用いられる。また、増粘剤にポリアクリル酸ナトリウムを適用した場合、架橋剤として、水酸化リチウム，水酸化亜鉛，水酸化アルミニウム，ほう酸ナトリウム等の多価金属塩が添加されるのが好ましい。特に、亜鉛塩，アルミニウム塩が好ましい。架橋反応が促進される。 架橋剤として添加される多価金属塩の濃度は、増粘剤（又は水溶性高分子）１当量に対し０．５〜１．５当量が好ましい。多価金属塩の濃度が０．５当量より小さくなるにつれ反応が遅すぎてゲル強度が低くなる傾向が現れだし、多価金属塩の濃度が１．５当量より大きくなるにつれ反応が速すぎてゲル化が不均一になり作業性が低下する傾向が現れだし、いずれも好ましくない。
Wetting agents such as polyhydric alcohols such as glycerin, propylene glycol and sorbitol, and fillers such as kaolin, zinc oxide, talc, titanium, bentonite, aluminum silicate, titanium oxide, zinc oxide, aluminum metasilicate, calcium sulfate and calcium phosphate Etc. may be added. In addition, propylene carbonate, crotamiton, l-menthol, peppermint oil, limonene, diisopropyl adipate and the like as dissolution aids or absorption enhancers, and methyl salicylate, glycol salicylate, l-menthol, thymol, mint oil, Nonylate vanillylamide, capsicum extract and the like may be added. Further, if necessary, a stabilizer, an antioxidant, an emulsifier, and the like may be added.
In addition, a crosslinking agent, a polymerizing agent, and the like may be added as necessary. The paste can be strengthened and can have water retention. The crosslinking agent and the polymerizing agent are appropriately selected according to the type of the thickener and the like. For example, when polyacrylic acid or polyacrylate is applied as a thickener, a compound having at least two epoxy groups in a molecule, a hydrochloride such as Ca, Mg, or Al, a sulfate, a phosphate, Inorganic acid salts such as carbonates, organic acid salts such as citrate, tartrate, gluconate, stearate, oxides such as zinc oxide and silicic acid, hydroxides such as aluminum hydroxide and magnesium hydroxide And the like are preferably used. When polyvinyl alcohol is used as the thickener, adipic acid, thioglycolic acid, epoxy compound (epichlorohydrin), aldehydes, N-methylol compound, Al, Ti, Zr, Sn, V, Cu, B, Cr Complexes such as compounds such as are preferably used. When polyvinylpyrrolidone is used as the thickener, a methyl vinyl ether / maleic anhydride copolymer, a polyacid compound or an alkali metal salt thereof (polyacrylic acid, tannic acid and derivatives thereof) and the like are preferably used. When polyethylene oxide is used as the thickener, perchioside, polysulfone azide and the like are preferably used. When a methyl vinyl ether / maleic anhydride copolymer is used as the thickener, polyfunctional hydroxy compounds, polyamines, iodine, gelatin, polyvinylpyrrolidone, iron, mercury, lead salts, and the like are preferably used. When gelatin is used as the thickener, aldehydes such as formaldehyde, glutaraldehyde and dialdehyde starch, diepoxides such as glyoxal and butadiene oxide, diketones such as divinyl ketone, and diisocyanates are preferably used. When sodium polyacrylate is used as the thickener, a polyvalent metal salt such as lithium hydroxide, zinc hydroxide, aluminum hydroxide, and sodium borate is preferably added as a crosslinking agent. Particularly, zinc salts and aluminum salts are preferred. The crosslinking reaction is accelerated. The concentration of the polyvalent metal salt added as a crosslinking agent is preferably 0.5 to 1.5 equivalents per equivalent of the thickener (or water-soluble polymer). As the concentration of the polyvalent metal salt becomes smaller than 0.5 equivalent, the reaction becomes too slow and the gel strength tends to decrease, and as the concentration of the polyvalent metal salt becomes larger than 1.5 equivalent, the reaction becomes too fast. There is a tendency that the gelation becomes non-uniform and the workability tends to decrease, and neither is preferable.
パップ剤としては、皮膚密着性がよいこと、有効成分の皮膚吸収を高めること、水分を可及的に多く含有していること、膏体中の水分が蒸発するとき皮膚から熱を奪うが、この発熱量が清涼感を与え、また角質層が内部から蒸散してくる水分子によって水和され、薬物の吸収が促進されること、常温又はその近辺の温度でもだれないこと、剥がす時に痛くなく汚れが残らないこと、べとつかないこと等が挙げられる。このため、膏体は、増粘剤５重量％〜２０重量％，好ましくは１０重量％〜１５重量％、湿潤剤５重量％〜４０重量％、充填剤２０重量％以下、水１０重量％〜８０重量％、溶解補助剤０〜８重量％、薬物５重量％以下，好ましくは０．５重量％〜５重量％とされるのが好ましい。
また、硬膏剤等に適用する場合、この基材としては、アクリル系共重合体，Ａ−Ｂ−Ａ型ブロック共重合体，脂環族系石油樹脂，軟化剤を有するものが好適に用いられる。更にＡ−Ｂ型ブロック共重合体やその他のポリブテンゴム，ブチルゴム，シリコーンゴム，天然ゴム，スチレン−ブタジエンコポリマー，ＮＢＲポリイソブチレン，ポリアルキアクリレート，合成イソプレン等の熱可塑性弾性剤等や、テルペン系樹脂，石油系樹脂，ロジン，水添ロジン，ロジン・水添ロジンエステルなどの粘着性付与剤，流動パラフィン，オリーブ油，大豆油，牛脂，トン脂等の動植物油、ポリブテン，液状ポリイソブチレン，低級イソプレン，ワックスなどの接着力・保持力調整剤、酸化チタン，酸化亜鉛，メタケイ酸アルミニウム，硫酸カルシウム，リン酸カルシウムなどの充填剤等が配合される。Ａ−Ｂ−Ａ型ブロック共重合体やＡ−Ｂ型ブロック共重合体としては、モノビニル置換芳香族化合物Ａと共役ジオレフィン共重合体Ｂとのブロック共重合体が好適に用いられる。具体的にはシェル化学社製のカリフレックスＴＲ−１１０１，カリフレックスＴＲ−１１０７，カリフレックスＴＲ−１１１１等、フィリップペトロリアム製のソルプレン４１８やソルプレン３１１等であり、その配合量は膏体組成物中１０〜４０重量部であり、好ましくは１５〜３０重量部である。Ａ−Ｂ型ブロック共重合体を１５〜３０重量部加えることにより、Ａ−Ｂ−Ａ型ブロック共重合体の薬効成分の相溶性や投錨力、粘着力を向上させるとともに油状成分による凝集力を改善することができ、この範囲よりも外れるに従い、これらの効果を減少させる傾向があるので好ましくない。
As a cataplasm, it has good skin adhesion, enhances skin absorption of active ingredients, contains as much water as possible, and removes heat from the skin when the water in the plaster evaporates, This calorific value gives a refreshing feeling, and the stratum corneum is hydrated by water molecules evaporating from the inside, promoting absorption of the drug, not drooling at room temperature or near temperature, painless when peeling off There are no stains left and no stickiness. For this reason, the plaster contains 5% to 20% by weight of a thickener, preferably 10% to 15% by weight, 5% to 40% by weight of a wetting agent, 20% by weight or less of a filler, and 10% by weight of water. It is preferably 80% by weight, solubilizer 0-8% by weight, drug 5% by weight or less, preferably 0.5-5% by weight.
When applied to a plaster or the like, as the base material, one having an acrylic copolymer, an ABA type block copolymer, an alicyclic petroleum resin, or a softener is suitably used. . Furthermore, thermoplastic elastomers such as AB type block copolymers and other polybutene rubbers, butyl rubbers, silicone rubbers, natural rubbers, styrene-butadiene copolymers, NBR polyisobutylene, polyalkyl acrylates, synthetic isoprenes, and terpene resins , Petroleum resins, tackifiers such as rosin, hydrogenated rosin, rosin and hydrogenated rosin ester, liquid paraffin, olive oil, soybean oil, tallow, tongue and other animal and vegetable oils, polybutene, liquid polyisobutylene, lower isoprene, An adhesive / holding power regulator such as wax, a filler such as titanium oxide, zinc oxide, aluminum metasilicate, calcium sulfate, calcium phosphate and the like are blended. As the ABA type block copolymer or the AB type block copolymer, a block copolymer of a monovinyl-substituted aromatic compound A and a conjugated diolefin copolymer B is suitably used. Specific examples thereof include Kaliflex TR-1101, Kariflex TR-1107, and Kariflex TR-1111 manufactured by Shell Chemical Co., Ltd., and Solprene 418 and 311 manufactured by Philippe Petroleum. It is 10 to 40 parts by weight, preferably 15 to 30 parts by weight. By adding 15 to 30 parts by weight of the AB block copolymer, the compatibility, anchoring power and adhesive strength of the active ingredient of the ABA block copolymer are improved, and the cohesive force due to the oil component is improved. It can be improved, and as the value goes out of this range, these effects tend to decrease, which is not preferable.
薬物としては、サリチル酸メチル，サリチル酸グリコール，ｌ−メントール，トウガラシエキス，ノニル酸ワニリルアミド，ハッカ油，ジクロフェナク，イブプロフェン，インドメタシン，ケトプロフェン，ロキソプロフェン，スリンダク，トルメチン，ロベンザリット，ペニシラミン，フェンプフェン，フルルビプロフェン，ナプロキセン，プラノプロフェン，チアプロフェン，スプロフェン，フェルビナク，ケトロラク，オキサプロジン，エトドラク，ザルトプロフィン，ピロキシカム，ペンタゾシン，塩酸ブプレノルフィン，酒石酸ブトルファノール等およびそのエステル誘導体または塩より選ばれた少なくとも１種の非ステロイド系抗炎症薬や、プレドニゾロン，デキサメタゾン，ヒドロコルチゾン，ベタメタゾン，フルオシニド，フルオシノロンアセトニド，吉草酸酢酸プレドニゾロン，ジプロピオン酸デキサメタゾン，吉草酸ジフルコルトロン，ジフルプレドナート，吉草酸ベタメタゾン，酪酸ヒドロコルチゾン，酪酸クロベタゾン，酪酸ベタメタゾン，プロピオン酸クロベタゾン，コハク酸デキサメタゾン，プレドニゾロン２１−（２Ｅ，６Ｅ）ファルネシート，吉草酸ヒドロコルチゾン，酢酸ジフロラゾン，プロピオン酸デキサメタゾン，ジプロピオン酸ベタメタゾン，アムシノニド，吉草酸デキサメタゾン，ハルシノニド，ブテソニド，プロピオン酸アルクロメタゾン等のステロイド系抗炎症薬等が挙げられるが、これらに限定されるものではない。薬物は、必要に応じて２種類以上併用することも可能である。また、これらの薬物は必要に応じてエステル体に誘導された化合物，アミド体に誘導された化合物，アセタール体に誘導された化合物，あるいは医学的に許容される無機塩，有機塩の形態でもって膏体に含有または付着されてもよい。薬物の量は、患者に適用した際にあらかじめ設定された有効量を患部に適用できるように、パップ剤や硬膏剤等の貼付剤の種類，用途等に応じて適宜選択される。 Drugs include methyl salicylate, glycol salicylate, l-menthol, pepper extract, vanillylamide nonylate, peppermint oil, diclofenac, ibuprofen, indomethacin, ketoprofen, loxoprofen, sulindac, tolmetin, robenzalit, penicillamine, fempfenen, flurbiprofena At least one non-steroidal anti-inflammation selected from the group consisting of, pranoprofen, thiaprofen, suprofen, felbinac, ketorolac, oxaprozin, etodolac, zaltoprofin, piroxicam, pentazocine, buprenorphine hydrochloride, butorphanol tartrate, etc. and ester derivatives or salts thereof Drugs, prednisolone, dexamethasone, hydrocortisone, betamethasone, fluocinide, Luocinolone acetonide, prednisolone acetate valerate, dexamethasone dipropionate, diflucortron valerate, difluprednate, betamethasone valerate, hydrocortisone butyrate, clobetasone butyrate, betamethasone butyrate, clobetasone propionate, dexamethasone succinate, prednisolone 21- (2E, 6E) Farneseat, hydrocortisone valerate, diflorazone acetate, dexamethasone dipropionate, betamethasone dipropionate, amcinonide, dexamethasone valerate, steroidal anti-inflammatory drugs such as halcinonide, butesonide, alclomethasone propionate, and the like. However, the present invention is not limited to this. If necessary, two or more drugs can be used in combination. These drugs may be in the form of a compound derived from an ester, a compound derived from an amide, a compound derived from an acetal, or a medically acceptable inorganic or organic salt, if necessary. It may be contained or adhered to the plaster. The amount of the drug is appropriately selected according to the type and use of a patch such as a cataplasm or a plaster so that an effective amount set in advance when applied to a patient can be applied to an affected part.
本発明の貼付剤は、一態様において、前記剥離シートと前記支持体の伸縮率の差が０．３％以上である構成を有している。
これにより、前記の作用の他、以下の作用が得られる。
（１）剥離シートと支持体等を左右に引張るだけで、剥離シートと支持体等との伸び率の違いを利用して、剥離シートのみを極めて容易に分断できる。
（２）分断時、剥離シートが弾性により分断された部位がめくれ上がるので、そのめくれ上がった剥離シートの各片を摘み取ることで、剥離シートを容易に剥ぎ取ることができる。
（３）剥離シートの各片を摘んだ際、膏体の露出した部分を患部に貼着するだけで手を汚すことなく貼着することができる。
（４）剥離シートがめくれ、膏体の一部が露出されるので、この膏体の露出部を患部にあて、次いで、めくれた剥離シートの各片をつまんで左右に引張るだけで、高齢者でも手間をかけずに、また手を汚すことなく、更にパップ剤や硬膏剤等の貼付剤にシワがよったりすることなくきれいに患部に貼着することができる。
Patch of the invention, Oite to an aspect, the difference in expansion ratio of the release sheet and the support member has a structure at least 0.3%.
As a result, the following operation can be obtained in addition to the above operation.
(1) Only by pulling the release sheet and the support and the like to the left and right, the release sheet alone can be extremely easily separated by utilizing the difference in elongation between the release sheet and the support and the like.
(2) At the time of division, the part where the release sheet is divided by elasticity is turned up, so that the release sheet can be easily peeled off by picking each piece of the peeled-off release sheet.
(3) When each piece of the release sheet is picked, the exposed portion of the plaster can be attached only to the affected part without soiling the hands.
(4) Since the peeling sheet is turned up and a part of the plaster is exposed, the exposed part of the plaster is applied to the affected area, and then, each piece of the peeled-off peeling sheet is pinched and pulled left and right. However, it can be stuck to the affected part neatly without trouble, without soiling the hands, and without wrinkling on patches such as cataplasms and plasters.
以上のように、本発明の貼付剤によれば、以下のような有利な効果が得られる。
（１）剥離シートと支持体等を左右に引張るだけで、剥離シートと支持体等との伸び率の違いを利用して、剥離シートのみを切れ目部で分断できる。
（２）分断時、剥離シートが弾性により分断された部位がめくれ上がるので、そのめくれ上がった剥離シートの各片を摘み取ることで、剥離シートを容易に剥ぎ取ることができる。
（３）剥離シートの各片を摘んだ際、膏体の露出した部分を患部に貼着するだけで手を汚すことなく貼着することができる。
（４）剥離シートがめくれ、膏体の一部が露出されるので、この膏体の露出部を患部にあて、次いで、めくれた剥離シートの各片をつまんで左右に引張るだけで、高齢者でも手間をかけずに、また手を汚すことなく、更にパップ剤や硬膏剤等の貼付剤にシワがよったりすることなくきれいに患部に貼着することができる。
（５）剥離シートの表面にエンボス加工部が形成されていることにより、剥離シートを分断するときや、パップ剤や硬膏剤等の貼付剤を製造するとき等、このエンボス加工部が指や膏体との摩擦抵抗を大とすることができ、剥離シートを手で摘み易くしたり、支持体上に展着された膏体上に剥離シートを貼着して原反シートを作成するときやこの原反シートを裁断するとき等、剥離シートを膏体上に密着させることができ、剥離シートが膏体からずれること等が防止できる。
As described above, according to the adhesive preparation of the present invention, Ru obtained the following advantageous effects.
(1 ) By simply pulling the release sheet and the support and the like to the left and right, the release sheet alone can be cut at the cut portion by utilizing the difference in the elongation rate between the release sheet and the support and the like.
(2) At the time of division, the part where the release sheet is divided by elasticity is turned up, so that the release sheet can be easily peeled off by picking each piece of the peeled-off release sheet.
(3) When each piece of the release sheet is picked, the exposed portion of the plaster can be attached only to the affected part without soiling the hands.
(4) Since the peeling sheet is turned up and a part of the plaster is exposed, the exposed part of the plaster is applied to the affected area, and then, each piece of the peeled-off peeling sheet is pinched and pulled left and right. However, it can be stuck to the affected part neatly without trouble, without soiling the hands, and without wrinkling on patches such as cataplasms and plasters.
(5) Since the embossed portion is formed on the surface of the release sheet, the embossed portion is formed with a finger or a plaster when dividing the release sheet or manufacturing a patch such as a poultice or plaster. It is possible to increase the frictional resistance with the body, make it easy to pick the release sheet by hand, or when creating a raw sheet by sticking the release sheet on the plaster spread on the support such as when cutting the original sheet, the release sheet can be adhered onto the plaster, release sheet Ru possible prevention may deviate from the plaster.
（６）剥離シートが、剥離シートの表面に形成されたエンボス加工部を備えたので、支持体の隅部を爪で探る等の剥離開始作業を要することなく、ただこのパップ剤や硬膏剤等の貼付剤の剥離シートを支持体等とともに外側に引張るだけで、容易に剥離シートのみを切れ目部で分断することができる。(6) Since the release sheet is provided with an embossed portion formed on the surface of the release sheet, there is no need to perform a peeling start operation such as searching for a corner of the support with a nail, and the pulp or plaster is simply used. By simply pulling the release sheet of the patch together with the support and the like outward, only the release sheet can be easily divided at the cut portion.
（７）剥離シートにエンボス加工部が形成されているので、剥離作業の際に滑ったりすることがなく、剥離シートの剥離を簡単にかつ円滑に行うことができる。(7) Since the embossed portion is formed on the release sheet, the release sheet can be easily and smoothly released without slipping during the release operation.
（８）剥離シートにエンボス加工部が形成されているので、パップ剤や硬膏剤等の貼付剤を製造するに際して、支持体の一面に展着された膏体上に剥離シートを積層する場合、剥離シートが膏体上を滑ってずれることがなく積層することができる。(8) Since an embossed portion is formed on the release sheet, when manufacturing a patch such as a poultice or plaster, when a release sheet is laminated on a plaster spread on one surface of a support, The release sheet can be laminated without slipping on the plaster.
（９）エンボス加工部の摩擦抵抗が大きいので原反シートを裁断する場合、刃具に原反シートが巻き込まれるのを防止し剥離シートがずれ込むことがなく、生産性を向上させることができる。(9) When the raw sheet is cut because the frictional resistance of the embossed portion is large, it is possible to prevent the raw sheet from being caught in the cutting tool, prevent the release sheet from slipping, and improve the productivity.
（１０）膏体やこの膏体と剥離シートの間に気泡が生じた場合も、この気泡をエンボス加工部によって容易に排出することができるので、製品歩留りを飛躍的に向上させることができる。(10) Even when air bubbles are generated between the plaster or the plaster and the release sheet, the air bubbles can be easily discharged by the embossed portion, so that the product yield can be significantly improved.
以下、本発明を実施するための最良の形態を、図面を参照しながら説明する。
（実施の形態１）
図１は本発明の実施の形態１における貼付剤を示す斜視図であり、図２はその正面図であり、図３はその要部断面図である。
図１乃至図３において、１ａは本発明の実施の形態１におけるパップ剤や硬膏剤等の貼付剤、２は不織布等からなる伸縮性を有する支持体、３は支持体２の表面の略全面に展着されたポリアクリル酸ナトリウム等にサリチル酸メチル又はケトプロフェン等の薬物や水分等を含有させた膏体、４は膏体３の全面に貼着された厚み１０μｍ〜７５μｍの無延伸ポリプロピレン等からなる剥離シート、４ａは剥離シート４の端部、５ａは剥離シート４の略中央部を横切って略直線状に形成された切れ目部、６は切れ目部５ａと切れ目部５ａとの間に形成された連結部、７ａは剥離シート４の略全面に菱形状の凸部を持って形成されたエンボス加工部である。
尚、連結部６の長さ（ａ）と切れ目部５ａの長さ（ｂ）の比は、ａ：ｂ＝１：８〜２５とされている。
また、切れ目部５ａを持った剥離シート４の引張り強度は、１０ｇ／ｃｍ 〜１４０ｇ／ｃｍである。
Hereinafter, the best mode for carrying out the present invention will be described with reference to the drawings.
(Embodiment 1)
FIG. 1 is a perspective view showing a patch in Embodiment 1 of the present invention, FIG. 2 is a front view thereof, and FIG. 3 is a cross-sectional view of a main part thereof.
1 to 3,
The ratio between the length (a) of the connecting
The tensile strength of the
ここで、剥離シートに形成された切れ目部とは、剥離シートの分断される部位，例えば剥離シートの略中央部や周辺部等に点在状に所定間隔の連結部を持って形成される切断部をいうものである。
該切断部は、連結部（ａ）とこの切れ目部（ｂ）の長さの比が、ａ：ｂ＝１：５〜２５，好ましくはａ：ｂ＝１：８〜２０，更に好ましくはａ：ｂ＝１：８〜１５とされるのが好ましい。切れ目部の長さが連結部の長さの８倍より小さくなるにつれ使用時以外でも分断し易くなり、薬効成分が揮発して薬効効果が低下したり、剥離シートが薄過ぎて摘み難くなり、信頼性や利便性が低下する傾向が現れだすので好ましくない。切れ目部の長さが連結部の長さの１５倍より大きくなるにつれ剥離シートの分断が困難となり、製造に際して原反シートを切断することが困難となり、利便性や作業性等が低下する傾向が現れだすので、好ましくない。
切れ目部は、剥離シートの所定部に直線状，Ｓ字状，波形状，鋸刃形状等に形成される。特に、Ｓ字状，波形状，鋸刃形状等に形成されると、一定間隔を空けて形成された突出片を摘んで剥離シートの剥離をスムーズに行うことができ、剥離作業等の利便性を向上させることができる。
切れ目部からの薬効成分や水分の逃散は剥離シートの張力をかけることにより、切れ目部が重なり合うことによって防止される。
Here, the cut portion formed in the release sheet refers to a cut formed at a portion where the release sheet is divided , for example, at a substantially central portion or a peripheral portion of the release sheet with connecting portions interspersed at predetermined intervals. Part.
In the cut portion , the ratio of the length of the connecting portion (a) to the cut portion (b) is a: b = 1: 5 to 25, preferably a: b = 1: 8 to 20, and more preferably a: b. : B = 1: 8 to 15 is preferred. As the length of the cut part becomes smaller than 8 times the length of the connecting part, it becomes easier to break even when not in use, the medicinal component volatilizes and the medicinal effect decreases, and the release sheet becomes too thin and difficult to pick, It is not preferable because reliability and convenience tend to decrease. As the length of the cut portion becomes larger than 15 times the length of the connecting portion, the separation of the release sheet becomes difficult, and it becomes difficult to cut the raw sheet at the time of manufacturing, and the convenience and workability tend to decrease. It is undesirable because it appears.
The cut portion is formed in a predetermined portion of the release sheet in a linear shape, an S shape, a wavy shape, a saw blade shape, or the like. In particular, when it is formed in an S shape, a wave shape, a saw blade shape, or the like, the protruding pieces formed at regular intervals can be picked up, and the peeling sheet can be smoothly peeled, which is convenient for the peeling operation and the like. Can be improved.
The escape of the medicinal component and the moisture from the cut portion is prevented by applying the tension of the release sheet and overlapping the cut portions.
以上のように構成された本実施の形態における貼付剤１ａについて、以下その使用方法を説明する。
図４は本発明の実施の形態１における貼付剤の剥離シートを分断する作業を示す側面図であり、図５は本発明の実施の形態１における貼付剤を患部に貼着する作業を示す側面図である。
まず、図４に示すように、パップ剤や硬膏剤等の貼付剤１ａの両端部をつまみ、支持体２と共に剥離シート４を引っ張り切れ目部５ａを少し折り曲げるだけで、剥離シート４を切れ目部５ａに沿って左右に分断することができる。また、分断された剥離シート４は、切れ目部５ａの部分を少し折り曲げるだけで剥離シート４の弾性によって分断された部分からめくれ上がり、膏体３が露出される。
次に、図５に示すように、この露出された膏体３を患部にあてながら、めくれた剥離シート４の各片を左右に引っ張って剥がしながら、患部にパップ剤や硬膏剤等の貼付剤１ａを貼着する。これにより、手を汚すことなくまたパップ剤や硬膏剤等の貼付剤１ａにシワがよったりすることはなくきれいに貼付剤１ａを貼着することができる。
The method of using the
FIG. 4 is a side view showing an operation of separating the patch release sheet according to the first embodiment of the present invention, and FIG. 5 is a side view showing an operation of attaching the adhesive patch to the affected part according to the first embodiment of the present invention. FIG.
First, as shown in FIG. 4, the both ends of the
Next, as shown in FIG. 5, while applying the exposed
以上のように本実施の形態のパップ剤や硬膏剤等の貼付剤１ａは構成されているので、以下の作用を有する。
（１）剥離シート４が引張り強度に優れた材料からなり、またエンボス加工部７ａで補強され腰が強化され、一方、支持体２が伸縮性に優れた材料からなるので、これら剥離シート４と支持体２の伸び率の違いを利用することにより、パップ剤や硬膏剤等の貼付剤１ａの両端部を持って支持体２と共に剥離シート４を左右に引張るだけで、剥離シート４を切れ目部５ａに沿って分断でき、かつ、分断された剥離シート４がその弾力でめくれ上がり膏体を露出することができ、手を汚すことなくまたパップ剤や硬膏剤等の貼付剤１ａにシワがよったりすることなくきれいに患部に貼着することができる。
（２）片手でパップ剤や硬膏剤等の貼付剤１ａの切れ目部５ａを指でこするだけで、エンボス加工部７ａの摩擦抵抗が高く指が掛かり易いので、剥離シート４をきれいに分断できる。
（３）分断された一方の剥離シート４片をめくり患部に貼付した後、他の剥離片を剥がすだけで貼付できる。
As described above, since the
(1) Since the
(2) Just by rubbing the
(3) After turning off one of the four separated release sheets and attaching the separated release sheet to the affected area, it can be attached by simply peeling off the other release sheet.
（実施の形態２）
図６は本発明の実施の形態２における貼付剤の正面図である。４は剥離シート、４ａは剥離シート４の端部、６は連結部であり、これらは実施の形態１と同様なものであり、同一の符号を付して説明を省略する。実施の形態１と異なるのは、本実施の形態における貼付剤１ｂが、剥離シート４の略中央部を横切って略波線状に形成された切れ目部５ｂと、剥離シート４の略全面に丸形状の凸部を持って形成されたエンボス加工部７ｂと、を備えた点である。
以上のように本実施の形態によれば、パップ剤や硬膏剤等の貼付剤をわずかな力で左右に引張ったり、剥離シート４の表面のエンボス加工部７ｂをこすったりして切れ目部５ｂで容易に分断され、めくられた剥離シート４の山部は突出して突出片となるのでこの突出片を摘んで、膏体から容易に剥がすことができる。
(Embodiment 2)
FIG. 6 is a front view of the patch according to the second embodiment of the present invention.
As described above, according to the present embodiment, a patch such as a cataplasm or a plaster is pulled to the left and right with a slight force, or the embossed portion 7b on the surface of the
（実施の形態３）
図７は本発明の実施の形態３における貼付剤の要部正面図である。４は剥離シート、６は連結部であり、これらは実施の形態１と同様なものであり、同一の符号を付して説明を省略する。実施の形態１と異なるのは、本実施の形態における貼付剤１ｃが、剥離シート４の略中央部を横切って略波形状に形成された切れ目部５ｃと、剥離シート４の略全面に三角形状の凸部を持って形成されたエンボス加工部７ｃと、を備えた点である。
(Embodiment 3)
FIG. 7 is a front view of a main part of the patch according to the third embodiment of the present invention.
（実施の形態４）
図８は本発明の実施の形態４における貼付剤の要部正面図である。４は剥離シート、６は連結部であり、これらは実施の形態１と同様なものであり、同一の符号を付して説明を省略する。実施の形態１と異なるのは、本実施の形態における貼付剤１ｄが、剥離シート４の略中央部を横切って略鋸刃形状に形成された切れ目部５ｄと、剥離シート４の略全面に星形状の凸部を持って形成されたエンボス加工部７ｄと、を備えた点である。
(Embodiment 4)
FIG. 8 is a main part front view of the patch according to
（実施の形態５）
図９は本発明の実施の形態５における貼付剤を示す斜視図である。２は支持体、３は膏体、４は剥離シート、４ａは剥離シート４の端部、６は連結部であり、これらは実施の形態１乃至実施の形態４と同様なものであり、同一の符号を付して説明を省略する。実施の形態１と異なるのは、本実施の形態における貼付剤１ｅが、剥離シート４の一端部の側部を横切って略直線状に形成された切れ目部５ｅと、切れ目部５ｅの両側部に幅が１０〜２０mmに渡って菱形状の凸部を持って形成されたエンボス加工部を備えた点である。
(Embodiment 5)
FIG. 9 is a perspective view showing a patch in Embodiment 5 of the present invention. 2 is a support, 3 is a plaster, 4 is a release sheet, 4a is an end of the
（実施の形態６）
図１０は本発明の実施の形態６における貼付剤を示す斜視図である。２は支持体、３は膏体、４は剥離シート、４ａは剥離シート４の端部、５ａは切れ目部、６は連結部、７ａはエンボス加工部であり、これらは実施の形態１と同様なものであり、同一の符号を付して説明を省略する。実施の形態１と異なるのは、本実施の形態における貼付剤１ｆが、エンボス加工部７ａに剥離位置等を印刷で解り易く表示した表示部８を備えた点である。
(Embodiment 6)
FIG. 10 is a perspective view showing a patch in the sixth embodiment of the present invention. 2 is a support, 3 is a plaster, 4 is a release sheet, 4a is an end of the
以下、更に具体化した実施例について説明する。
（実施例１）
長さ１５０mm，幅５０mm，厚み３０μｍの無延伸ポリプロピレン（ＣＰＰ）製，延伸ポリプロピレン（ＯＰＰ）製，ポリエチレンテレフタレート（ＰＥＴ）製の剥離シートを準備した。
次に、各剥離シートの略中央部に、連結部の長さ（ａ）と切れ目部の長さ（ｂ）の比が、ａ：ｂ＝１：５の直線状の切れ目部を設けた。
Hereinafter, more specific embodiments will be described.
(Example 1)
A release sheet made of unstretched polypropylene (CPP), stretched polypropylene (OPP), and polyethylene terephthalate (PET) having a length of 150 mm, a width of 50 mm, and a thickness of 30 μm was prepared.
Next, a linear cut portion where the ratio of the length (a) of the connecting portion to the length (b) of the cut portion was a: b = 1: 5 was provided substantially at the center of each release sheet.
（実施例２）
実施例１と同様にして剥離シートを準備した。
次に、各剥離シートの略中央部に、連結部の長さ（ａ）と切れ目部の長さ（ｂ）の比が、ａ：ｂ＝１：８の直線状の切れ目部を設けた。
(Example 2)
A release sheet was prepared in the same manner as in Example 1.
Next, a linear cut portion in which the ratio of the length (a) of the connecting portion to the length (b) of the cut portion was a: b = 1: 8 was provided substantially at the center of each release sheet.
（実施例３）
実施例１と同様にして剥離シートを準備した。
次に、各剥離シートの略中央部に、連結部の長さ（ａ）と切れ目部の長さ（ｂ）の比が、ａ：ｂ＝１：１５の直線状の切れ目部を設けた。
(Example 3)
A release sheet was prepared in the same manner as in Example 1.
Next, a linear cut portion in which the ratio of the length (a) of the connecting portion and the length (b) of the cut portion was a: b = 1: 15 was provided substantially at the center of each release sheet.
（官能試験）
各剥離シートを引張って、引き裂いたときの官能度を調べた。
評価方法は、各剥離シートの切れ目部を引き裂く際、非常に切れ易いと感じれば、「◎」とし、切れ易いと感じれば、「○」とし、切れ難いと感じれば、「×」として評価した。その結果を（表１）に示す。
(Sensory test)
Each release sheet was pulled and the functionality when torn was examined.
The evaluation method, when tearing the cut part of each release sheet, was evaluated as “◎” if it felt very easy to cut, “O” if it felt easy to cut, and “×” if it felt hard to cut. . The results are shown in (Table 1).
（引張り強度試験）
引張り試験機（島津製作所製；ＡＧＳ−１００Ｂ）を用いて、切れ目部を形成した各剥離シートの引張り強度を測定した。
ここで、標点間距離１００mmを持って剥離シートを幅５０mmのチャックで挟持させ、１００mm／分で引張り、破断時の荷重を測定した。この結果を（表１）に示す。
(Tensile strength test)
Using a tensile tester (AGS-100B, manufactured by Shimadzu Corporation), the tensile strength of each release sheet having a cut portion was measured.
Here, the release sheet was clamped with a chuck having a width of 50 mm with a distance between gauge points of 100 mm, pulled at a rate of 100 mm / min, and the load at break was measured. The results are shown in (Table 1).
（表１）から明らかなように、連結部の長さと切れ目部の長さの比が、実施例３（ａ：ｂ＝１：１５）のときは非常に分断が容易で、実施例２（ａ：ｂ＝１：８）のときでも分断が容易であった。しかしながら、連結部の長さと切れ目部の長さの比が、実施例１（ａ：ｂ＝１：５）のときは、分断がし難く一部に非切断部が確認された。
また、剥離シートの引っ張り強度は、連結部の長さと切れ目部の長さの比が、実施例３（ａ：ｂ＝１：１５）のときは、４０ｇ／cm〜５８ｇ／cm、実施例２（ａ：ｂ＝１：８）のときは、６９ｇ／cm〜９８ｇ／cm、実施例１（ａ：ｂ＝１：５）のときは、１５６ｇ／cm〜１８７ｇ／cmであった。
As is clear from (Table 1), when the ratio between the length of the connecting portion and the length of the cut portion is Example 3 (a: b = 1: 15), the division is very easy, and Example 2 ( (a: b = 1: 8), the separation was easy. However, when the ratio of the length of the connection portion to the length of the cut portion was Example 1 (a: b = 1: 5), the non-cut portion was confirmed in some portions because of difficulty in cutting.
Further, the tensile strength of the release sheet was 40 g / cm to 58 g / cm when the ratio of the length of the connection portion to the length of the cut portion was Example 3 (a: b = 1: 15), and Example 2 In the case of (a: b = 1: 8), it was 69 g / cm to 98 g / cm, and in the case of Example 1 (a: b = 1: 5), it was 156 g / cm to 187 g / cm.
本発明は、パップ剤や硬膏剤等の貼付剤に関し、パップ剤や硬膏剤等の貼付剤を左右に引張るだけで剥離シートを簡単に分断でき、剥離シートのめくれた部分を患部に貼着するだけで、高齢者でも簡単に手を汚すことなく、かつシワがよったりすることなくきれいに貼着することができる低原価で量産性に適したパップ剤や硬膏剤等の貼付剤を提供できる。 The present invention relates to a patch such as a poultice or a plaster, you can easily separate the release sheet by simply pulling the patch such as a poultice or a plaster to the left and right, bonding the everted portion of the release sheet to the affected area It is possible to provide adhesives such as cataplasms and plasters suitable for mass production at low cost that can be easily applied to elderly people without soiling their hands and without wrinkles. .
１ａ，１ｂ，１ｃ，１ｄ，１ｅ，１ｆ，１１ パップ剤や硬膏剤等の貼付剤
２，１２ 支持体
３，１３ 膏体
４，１４ 剥離シート
４ａ 剥離シートの端部
５ａ，５ｂ，５ｃ，５ｄ，５ｅ 切れ目部
６ 連結部
７ａ，７ｂ，７ｃ，７ｄ，７ｅ エンボス加工部
８ 表示部
1a, 1b, 1c, 1d, 1e, 1f, 11 Patches such as cataplasms and
Claims (1)
該貼付剤の両端部を持って左右に引張ることにより、前記剥離シートのみが切れ目部で分断される、前記貼付剤。 A support having elasticity, a plaster which is spreadable over substantially the entire surface of one side of the support, the embossed portion adhered to the entire surface of the plaster is formed, and elongation of the support is a patch that includes a single release sheet having a different elongation,
The patch , wherein only the release sheet is divided at a cut portion by pulling the patch to the left and right while holding both ends thereof.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2003316093A JP3566960B2 (en) | 2003-09-08 | 2003-09-08 | Patch |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2003316093A JP3566960B2 (en) | 2003-09-08 | 2003-09-08 | Patch |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001077126A Division JP3666582B2 (en) | 2001-03-16 | 2001-03-16 | Patch |
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| Publication Number | Publication Date |
|---|---|
| JP2004024905A JP2004024905A (en) | 2004-01-29 |
| JP3566960B2 true JP3566960B2 (en) | 2004-09-15 |
Family
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003316093A Expired - Lifetime JP3566960B2 (en) | 2003-09-08 | 2003-09-08 | Patch |
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| Country | Link |
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| JP (1) | JP3566960B2 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001335471A (en) * | 2000-05-23 | 2001-12-04 | Hisamitsu Pharmaceut Co Inc | Plaster |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050182443A1 (en) | 2004-02-18 | 2005-08-18 | Closure Medical Corporation | Adhesive-containing wound closure device and method |
| JP4607478B2 (en) * | 2004-03-17 | 2011-01-05 | 株式会社トクホン | Double-sided release film for patch |
| US20060009099A1 (en) | 2004-07-12 | 2006-01-12 | Closure Medical Corporation | Adhesive-containing wound closure device and method |
| JP4716355B2 (en) * | 2005-02-18 | 2011-07-06 | 大協薬品工業株式会社 | Adhesive patch with adhesive tape and method for producing the same |
| US10470934B2 (en) | 2016-09-29 | 2019-11-12 | Ethicon, Inc. | Methods and devices for skin closure |
| US10687986B2 (en) | 2016-09-29 | 2020-06-23 | Ethicon, Inc. | Methods and devices for skin closure |
| USD848624S1 (en) | 2016-09-29 | 2019-05-14 | Ethicon, Inc. | Release paper for wound treatment devices |
| US10470935B2 (en) | 2017-03-23 | 2019-11-12 | Ethicon, Inc. | Skin closure systems and devices of improved flexibility and stretchability for bendable joints |
| US11504446B2 (en) | 2017-04-25 | 2022-11-22 | Ethicon, Inc. | Skin closure devices with self-forming exudate drainage channels |
| KR102071430B1 (en) * | 2018-01-03 | 2020-04-01 | 김태효 | Friction control taping tape for foot and manufacturing method of it |
| US10993708B2 (en) | 2018-07-31 | 2021-05-04 | Ethicon, Inc. | Skin closure devices with interrupted closure |
-
2003
- 2003-09-08 JP JP2003316093A patent/JP3566960B2/en not_active Expired - Lifetime
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001335471A (en) * | 2000-05-23 | 2001-12-04 | Hisamitsu Pharmaceut Co Inc | Plaster |
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| JP2004024905A (en) | 2004-01-29 |
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