ITTO910865A1 - Composti triciclici. - Google Patents

Composti triciclici.

Info

Publication number: ITTO910865A1
Authority: IT; Italy
Prior art keywords: tricyclic compounds; tricyclic; compounds
Prior art date: 1990-11-16

Application number

IT000865A

Other languages

English (en)

Inventor

Jacob Berger

Robin D Clark

Original Assignee

Syntex Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-11-16

Filing date

1991-11-12

Publication date

1992-05-17

1991-11-12 Application filed by Syntex Inc filed Critical Syntex Inc

1991-11-12 Publication of ITTO910865A0 publication Critical patent/ITTO910865A0/it

1992-05-17 Publication of ITTO910865A1 publication Critical patent/ITTO910865A1/it

1995-03-30 Application granted granted Critical

1995-03-30 Publication of IT1250049B publication Critical patent/IT1250049B/it

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Otolaryngology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

ITTO910865A 1990-11-16 1991-11-12 Composti triciclici. IT1250049B (it)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/614,326 US5189041A (en)	1990-11-16	1990-11-16	Tricyclic 5-ht3 receptor antagonists

Publications (3)

Publication Number	Publication Date
ITTO910865A0 ITTO910865A0 (it)	1991-11-12
ITTO910865A1 true ITTO910865A1 (it)	1992-05-17
IT1250049B IT1250049B (it)	1995-03-30

Family

ID=24460766

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ITTO910865A IT1250049B (it)	1990-11-16	1991-11-12	Composti triciclici.

Country Status (17)

Country	Link
US (1)	US5189041A (it)
EP (1)	EP0485962A3 (it)
JP (1)	JPH04283587A (it)
KR (1)	KR920009828A (it)
AU (1)	AU8785291A (it)
CA (1)	CA2055680A1 (it)
FI (1)	FI915400A (it)
HU (1)	HUT59406A (it)
IE (1)	IE913987A1 (it)
IL (1)	IL100061A0 (it)
IT (1)	IT1250049B (it)
MX (1)	MX9102076A (it)
NO (1)	NO914490L (it)
PL (1)	PL292419A1 (it)
PT (1)	PT99518A (it)
TW (1)	TW208007B (it)
ZA (1)	ZA919078B (it)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PL166267B1 (pl) *	1989-11-28	1995-04-28	Syntex Inc	Sposób wytwarzania nowych zwiazków trójpierscieniowych PL PL PL PL
US5852014A (en) *	1992-03-12	1998-12-22	Smithkline Beecham P.L.C.	Condensed indole derivatives as 5HT4 -receptor antagonists
MY110110A (en) *	1992-03-12	1998-01-27	Smithkline Beecham Plc	Pharmaceuticals in the treatment of gastrointestinal disorders, cardiovascular disorders and cns disorders
MX9305947A (es) *	1992-09-29	1994-06-30	Smithkline Beecham Plc	Compuestos antagonistas del receptor 5-ht4, procedimiento para su preparacion y composiciones farmaceuticas que las contienen.
ATE161819T1 (de) *	1993-04-27	1998-01-15	Solvay Fluor & Derivate	Verfahren zur herstellung von carbonsäureestern aus carbonsäurehalogeniden und alkoholen
US6489355B2 (en) *	1993-12-01	2002-12-03	Eli Lilly And Company	Methods of inhibiting the effects of amyloidogenic proteins
US5723103A (en) *	1994-12-09	1998-03-03	Vanderbilt University	Substituted benzamides and radioligand analogs and methods of use
IT1303123B1 (it)	1998-10-13	2000-10-30	Rotta Research Lab	Derivati basici di benz(e)isoindol-1-oni e pirrolo(3,4-c)chinolin-1-oni ad attivita' 5ht3 antagonista, loro preparazione ed
EP1254115A2 (en) *	2000-02-11	2002-11-06	Bristol-Myers Squibb Company	Cannabinoid receptor modulators, their processes of preparation, and use of cannabinoid receptor modulators for treating respiratory and non-respiratory diseases
EP1284732A2 (en) *	2000-05-18	2003-02-26	Glaxo Group Limited	Method for treating functional dyspepsia using alosetron
AR036040A1 (es)	2001-06-12	2004-08-04	Upjohn Co	Compuestos de heteroarilo multiciclicos sustituidos con quinuclidinas y composiciones farmaceuticas que los contienen
AR036041A1 (es)	2001-06-12	2004-08-04	Upjohn Co	Compuestos aromaticos heterociclicos sustituidos con quinuclidina y composiciones farmaceuticas que los contienen
BR0214016A (pt)	2001-11-09	2004-10-13	Upjohn Co	Compostos azabicìclico-fenil-fundido heterocìclicos e seu uso como ligandos alfa 7 nachr
DE10164139A1 (de)	2001-12-27	2003-07-10	Bayer Ag	2-Heteroarylcarbonsäureamide
DE10234424A1 (de) *	2002-07-29	2004-02-12	Bayer Ag	Benzothiophen-, Benzofuran- und Indolharnstoffe
TWI355936B (en)	2003-02-18	2012-01-11	Helsinn Healthcare Sa	Uses of palonosetron hydrochloride
ITMI20031467A1 (it) *	2003-07-18	2005-01-19	Acraf	Farmaco attivo nel dolore neuropatico
NZ613291A (en)	2008-11-19	2014-11-28	Forum Pharmaceuticals Inc	Treatment of cognitive disorders with (r)-7-chloro-n-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide and pharmaceutically acceptable salts thereof
US9145396B2 (en)	2008-12-01	2015-09-29	Targacept, Inc.	Synthesis and novel salt forms of (R)-5-((E)-2-pyrrolidin-3ylvinyl)pyrimidine
SG185594A1 (en)	2010-05-17	2012-12-28	Envivo Pharmaceuticals Inc	A crystalline form of (r)-7-chloro-n-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide hydrochloride monohydrate
RU2017136693A (ru)	2012-05-08	2019-02-08	Форум Фармасьютикалз, Инк.	Способы поддержания, лечения или улучшения когнитивной функции

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2121394A1 (fr) *	1971-01-08	1972-08-25	Anvar	Procédé d'obtention de dérivés d'acides indole carboxyliques et produits préparables par ce procédé.
JPS5337696A (en) *	1976-08-26	1978-04-06	Omnium Chimique Sa	Hexahydrocantinonee6 derivative
FR2475394A1 (fr) *	1980-02-12	1981-08-14	Synthelabo	Compositions pharmaceutiques contenant l'hexahydro-1, 2, 3, 3a, 4, 5, 6h indolo (3, 2, 1 - d. e) (1, 5) naphtyridinone - 6
FI74707C (fi) *	1982-06-29	1988-03-10	Sandoz Ag	Foerfarande foer framstaellning av terapeutiskt anvaendbara alkylenoeverbryggade piperidylestrar eller -amider av bicykliska karboxylsyror.
GB8623142D0 (en) *	1986-09-26	1986-10-29	Beecham Group Plc	Compounds
JP2765845B2 (ja) *	1986-11-21	1998-06-18	グラクソ、グループ、リミテッド	中止症候群の予防の治療薬
DE3851597T2 (de) *	1987-09-03	1995-01-26	Glaxo Group Ltd., London	Lactamderivate.
DE3810552A1 (de) *	1988-03-29	1989-10-19	Sandoz Ag	Ester und amide von indol-, benzo(b)thiopen-, benzo(b)furancarbonsaeuren oder 4-amino-2-methoxy-benzolsaeuren mit n-heterocyclischen oder n-heterobicyclischen alkoholen oder aminen, verfahren zu deren herstellung sie enthaltende pharmazeutische zusammensetzungen sowie applikator zur verabreichung derselben
US5008272A (en) *	1988-08-15	1991-04-16	Glaxo Group Limited	Lactam derivatives
EP0377238A1 (en) *	1988-12-22	1990-07-11	Duphar International Research B.V	New annelated indolo (3,2-c)-lactams
GB8904551D0 (en) *	1989-02-28	1989-04-12	Glaxo Group Ltd	Chemical compounds
EP0392663A1 (en) *	1989-03-13	1990-10-17	Ono Pharmaceutical Co., Ltd.	Carboline derivative as a 5-HT3 receptor antagonist
JPH02290878A (ja) *	1989-04-28	1990-11-30	Ono Pharmaceut Co Ltd	ベンゾチエノ（フロ）ピリジン誘導体

1990
- 1990-11-16 US US07/614,326 patent/US5189041A/en not_active Expired - Fee Related
1991
- 1991-11-05 KR KR1019910020330A patent/KR920009828A/ko not_active Application Discontinuation
- 1991-11-12 EP EP19910119290 patent/EP0485962A3/en not_active Withdrawn
- 1991-11-12 IT ITTO910865A patent/IT1250049B/it active IP Right Grant
- 1991-11-15 AU AU87852/91A patent/AU8785291A/en not_active Abandoned
- 1991-11-15 PT PT99518A patent/PT99518A/pt not_active Application Discontinuation
- 1991-11-15 IL IL100061A patent/IL100061A0/xx unknown
- 1991-11-15 JP JP3300234A patent/JPH04283587A/ja active Pending
- 1991-11-15 PL PL29241991A patent/PL292419A1/xx unknown
- 1991-11-15 TW TW080108994A patent/TW208007B/zh active
- 1991-11-15 FI FI915400A patent/FI915400A/fi not_active Application Discontinuation
- 1991-11-15 MX MX9102076A patent/MX9102076A/es unknown
- 1991-11-15 NO NO91914490A patent/NO914490L/no unknown
- 1991-11-15 HU HU913579A patent/HUT59406A/hu unknown
- 1991-11-15 IE IE398791A patent/IE913987A1/en not_active Application Discontinuation
- 1991-11-15 CA CA002055680A patent/CA2055680A1/en not_active Abandoned
- 1991-11-15 ZA ZA919078A patent/ZA919078B/xx unknown

Also Published As

Publication number	Publication date
NO914490D0 (no)	1991-11-15
CA2055680A1 (en)	1992-05-17
ITTO910865A0 (it)	1991-11-12
IL100061A0 (en)	1992-08-18
JPH04283587A (ja)	1992-10-08
TW208007B (it)	1993-06-21
MX9102076A (es)	1992-07-08
HUT59406A (en)	1992-05-28
PL292419A1 (en)	1993-04-05
IT1250049B (it)	1995-03-30
EP0485962A3 (en)	1992-07-29
AU8785291A (en)	1992-05-21
IE913987A1 (en)	1992-05-20
FI915400A0 (fi)	1991-11-15
PT99518A (pt)	1992-09-30
NO914490L (no)	1992-05-18
HU913579D0 (en)	1992-01-28
US5189041A (en)	1993-02-23
ZA919078B (en)	1993-05-17
FI915400A (fi)	1992-05-17
KR920009828A (ko)	1992-06-25
EP0485962A2 (en)	1992-05-20

Publication	Publication Date	Title
NL350004I2 (nl)	2003-01-06	Aromatische verbindingen.
MX9201819A (es)	1992-12-01	Compuestos benzoheterociclicos.
FI923931A0 (fi)	1992-09-02	Anordning foer granskning av insidan av en foergrenad roerlinje.
FI910473L (fi)	1991-08-02	Naol - suturkombination.
DE69112037D1 (de)	1995-09-14	Waferträger.
MX9202978A (es)	1993-02-01	Compuestos de amino-4-aril-tiazoles.
FI914476L (fi)	1992-04-09	Tricykliska heterocykliska foereningar.
ITTO910865A1 (it)	1992-05-17	Composti triciclici.
DE69111876D1 (de)	1995-09-14	Ophthalmometer.
FI86244B (fi)	1992-04-30	Bakugn-spisugnkombination.
DE59104521D1 (de)	1995-03-16	Polkern.
FI913182A0 (fi)	1991-06-28	Tricykliska foereningar innehaollande heteroatomer.
DE69100071D1 (de)	1993-06-09	Kaefigmutter.
MX9202690A (es)	1992-12-01	Nuevos compuestos de cefem.
FI906123L (fi)	1991-07-30	Nytt uttryckningssystem foer svampar.
DE69110728D1 (de)	1995-08-03	8-Sulfamylmethylen-2-aminotetraline.
FI920268L (fi)	1992-07-26	Tricykliskt pyridonderivat.
DE59103525D1 (de)	1994-12-22	Honmachine.
DE59103481D1 (de)	1994-12-15	o-Aminoazoverbindungen.
DE69104797D1 (de)	1994-12-01	2-Substituierte-1-Hydroxyindole.
DE59104042D1 (de)	1995-02-09	Chlorphenylalkoxyalkyl-Verbindungen.
FI902430A0 (fi)	1990-05-16	Ben foer en stativkonstruktion.
MX9202143A (es)	1992-11-01	Compuestos.
FI902210A0 (fi)	1990-05-03	Kombinerat terraeng/vinter- och sommardaeck.
IT9018003V0 (it)	1990-12-03	Autoretrobloccante - a.r.b

Legal Events

Date	Code	Title	Description
1995-03-30	0001	Granted