[go: up one dir, main page]

IT9019571A0 - Composizioni terapeutiche a rilascio controllato di farmaci supportatisu polimeri reticolati e rivestiti con film polimerici,e loro processodi preparazione - Google Patents

Composizioni terapeutiche a rilascio controllato di farmaci supportatisu polimeri reticolati e rivestiti con film polimerici,e loro processodi preparazione

Info

Publication number
IT9019571A0
IT9019571A0 IT9019571A IT1957190A IT9019571A0 IT 9019571 A0 IT9019571 A0 IT 9019571A0 IT 9019571 A IT9019571 A IT 9019571A IT 1957190 A IT1957190 A IT 1957190A IT 9019571 A0 IT9019571 A0 IT 9019571A0
Authority
IT
Italy
Prior art keywords
coated
cross
polymer film
controlled release
therapeutic compositions
Prior art date
Application number
IT9019571A
Other languages
English (en)
Other versions
IT9019571A1 (it
IT1241417B (it
Inventor
Fabio Carli
Italo Colombo
Leonardo Rabaglia
Original Assignee
Vectorpharma Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vectorpharma Int filed Critical Vectorpharma Int
Publication of IT9019571A0 publication Critical patent/IT9019571A0/it
Priority to IT19571A priority Critical patent/IT1241417B/it
Priority to US07/620,651 priority patent/US5275824A/en
Priority to YU34491A priority patent/YU34491A/sh
Priority to CA002037410A priority patent/CA2037410C/en
Priority to EP91103224A priority patent/EP0446753B1/en
Priority to AT91103224T priority patent/ATE114242T1/de
Priority to DE69105222T priority patent/DE69105222T2/de
Priority to ES91103224T priority patent/ES2067068T3/es
Priority to KR1019910003465A priority patent/KR0175935B1/ko
Priority to HU91707A priority patent/HUT59588A/hu
Priority to PL28932291A priority patent/PL289322A1/xx
Priority to JP06373291A priority patent/JP3240387B2/ja
Priority to SU4894969/14A priority patent/RU2067859C1/ru
Publication of IT9019571A1 publication Critical patent/IT9019571A1/it
Application granted granted Critical
Publication of IT1241417B publication Critical patent/IT1241417B/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Communicable Diseases (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Vascular Medicine (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Luminescent Compositions (AREA)
IT19571A 1990-03-06 1990-03-06 Composizioni terapeutiche a rilascio controllato di farmaci supportatisu polimeri reticolati e rivestiti con film polimerici,e loro processodi preparazione IT1241417B (it)

Priority Applications (13)

Application Number Priority Date Filing Date Title
IT19571A IT1241417B (it) 1990-03-06 1990-03-06 Composizioni terapeutiche a rilascio controllato di farmaci supportatisu polimeri reticolati e rivestiti con film polimerici,e loro processodi preparazione
US07/620,651 US5275824A (en) 1990-03-06 1990-12-03 Therapeutic compositions with controlled release of medicaments supported on crosslinked polymers and coated with polymer films, and their preparation process
YU34491A YU34491A (sh) 1990-03-06 1991-02-27 Postupak za pravljenje terapeutskih preparata sa kontrolisanim oslobadjanjem lekova
CA002037410A CA2037410C (en) 1990-03-06 1991-03-01 Therapeutic compositions with controlled release of medicaments supported on crosslinked polymers and coated with polymer films, and their preparation process
DE69105222T DE69105222T2 (de) 1990-03-06 1991-03-04 Auf quervernetzte Polymere aufgebrachte und mit Polymerfilmen beschichtete therapeutische Zusammensetzungen mit kontrollierter Freisetzung von Medikamenten und deren Herstellungsverfahren.
AT91103224T ATE114242T1 (de) 1990-03-06 1991-03-04 Auf quervernetzte polymere aufgebrachte und mit polymerfilmen beschichtete therapeutische zusammensetzungen mit kontrollierter freisetzung von medikamenten und deren herstellungsverfahren.
EP91103224A EP0446753B1 (en) 1990-03-06 1991-03-04 Therapeutic compositions with controlled release of medicaments supported on crosslinked polymers and coated with polymer films and their preparation process
ES91103224T ES2067068T3 (es) 1990-03-06 1991-03-04 Composiciones terapeuticas con liberacion controlada de medicamentos soportados en polimeros reticulados y recubiertos con peliculas polimericas y sus procesos de preparacion.
KR1019910003465A KR0175935B1 (ko) 1990-03-06 1991-03-04 가교결합된 중합체 상에 지지되고 중합체 박막으로 피복된 약제의 방출이 조절되는 치료학적 조성물 및 이의 제조방법
HU91707A HUT59588A (en) 1990-03-06 1991-03-05 Retarde composition and process for producing it
PL28932291A PL289322A1 (en) 1990-03-06 1991-03-06 Method of obtaining a composition of controllable release of medicine contained therein
JP06373291A JP3240387B2 (ja) 1990-03-06 1991-03-06 架橋ポリマーで支持されポリマーフィルムで被覆された薬剤の制御された放出を伴なう治療組成物、及びそれらの調整方法
SU4894969/14A RU2067859C1 (ru) 1990-03-06 1991-03-06 Композиция с регулируемым выделением лекарственного средства

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT19571A IT1241417B (it) 1990-03-06 1990-03-06 Composizioni terapeutiche a rilascio controllato di farmaci supportatisu polimeri reticolati e rivestiti con film polimerici,e loro processodi preparazione

Publications (3)

Publication Number Publication Date
IT9019571A0 true IT9019571A0 (it) 1990-03-06
IT9019571A1 IT9019571A1 (it) 1991-09-06
IT1241417B IT1241417B (it) 1994-01-14

Family

ID=11159155

Family Applications (1)

Application Number Title Priority Date Filing Date
IT19571A IT1241417B (it) 1990-03-06 1990-03-06 Composizioni terapeutiche a rilascio controllato di farmaci supportatisu polimeri reticolati e rivestiti con film polimerici,e loro processodi preparazione

Country Status (13)

Country Link
US (1) US5275824A (it)
EP (1) EP0446753B1 (it)
JP (1) JP3240387B2 (it)
KR (1) KR0175935B1 (it)
AT (1) ATE114242T1 (it)
CA (1) CA2037410C (it)
DE (1) DE69105222T2 (it)
ES (1) ES2067068T3 (it)
HU (1) HUT59588A (it)
IT (1) IT1241417B (it)
PL (1) PL289322A1 (it)
RU (1) RU2067859C1 (it)
YU (1) YU34491A (it)

Families Citing this family (84)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2572673B2 (ja) * 1990-07-25 1997-01-16 エスエス製薬株式会社 徐放性錠剤
US5288505A (en) * 1991-06-26 1994-02-22 Galephar P.R., Inc., Ltd. Extended release form of diltiazem
US6764697B1 (en) * 1991-06-27 2004-07-20 Alza Corporation System for delaying drug delivery up to seven hours
GB2258613B (en) * 1991-08-12 1996-01-10 Euro Celtique Sa Pharmaceutical diltiazem formulation
KR100221695B1 (ko) * 1991-08-12 1999-09-15 그린 마틴, 브라이언 쥐 테슬리 약학적 구상 제형
IT1252867B (it) * 1991-12-31 1995-06-28 Gentili Ist Spa Composizioni farmaceutiche contenenti progesterone ad elevata biodisponibilita'
US5262173A (en) * 1992-03-02 1993-11-16 American Cyanamid Company Pulsatile once-a-day delivery systems for minocycline
DE4236090C1 (de) * 1992-10-26 1994-01-05 Asta Medica Arzneimittel Pharmazeutische Zubereitung für die Fluoridionen-Versorgung
RU2143896C1 (ru) * 1993-03-05 2000-01-10 Хексаль Аг Кристаллический комплекс циклодекстрина с гидрохлоридом ранитидина, способ его получения и содержащие его фармацевтические составы
GB9318880D0 (en) * 1993-09-11 1993-10-27 Smithkline Beecham Plc Pharmaceutical composition
US5484607A (en) * 1993-10-13 1996-01-16 Horacek; H. Joseph Extended release clonidine formulation
FR2711804B1 (fr) * 1993-10-22 1996-01-19 Pf Medicament Procédé de contrôle de la dissolution de formes galéniques à libération modifiée à l'aide d'un réactif solide et sachet dose contenant un tel réactif.
AT403988B (de) * 1994-05-18 1998-07-27 Lannacher Heilmittel Festes orales retardpräparat
AU692565B2 (en) * 1994-06-16 1998-06-11 Pharmacia & Upjohn S.P.A. Bioadhesive starches and process for their preparation
US5576311A (en) * 1994-11-30 1996-11-19 Pharmos Corporation Cyclodextrins as suspending agents for pharmaceutical suspensions
WO1996026719A1 (en) * 1995-03-02 1996-09-06 Takeda Chemical Industries, Ltd. A prolonged release composition, use and production thereof
JP3471977B2 (ja) * 1995-06-02 2003-12-02 信越化学工業株式会社 液体状可塑剤を用いる無溶媒腸溶性コーティング剤で被覆した腸溶性製剤
EP0761209A3 (en) * 1995-09-01 1998-02-04 J.B. Chemicals & Pharmaceuticals Ltd. Controlled release formulations of ranitidine
US5773031A (en) * 1996-02-27 1998-06-30 L. Perrigo Company Acetaminophen sustained-release formulation
HUP9600758A2 (en) * 1996-03-27 1998-03-02 Cyclolab Ciklodextrin Kutato F Diclofenac composition of diminished gastrointestinal irritation and enhanced biological resorption
IT1282381B1 (it) * 1996-04-29 1998-03-20 Trans Bussan S A Nuove formulazioni di diacereina, ottenute per inclusione del principio attivo in idrogel polisaccaridi
FR2757397B1 (fr) * 1996-12-23 1999-03-05 Mazal Pharma Composition pharmaceutique a base de rheine ou de diacerheine a biodisponibilite amelioree
US5891474A (en) * 1997-01-29 1999-04-06 Poli Industria Chimica, S.P.A. Time-specific controlled release dosage formulations and method of preparing same
US5788987A (en) * 1997-01-29 1998-08-04 Poli Industria Chimica Spa Methods for treating early morning pathologies
US6890524B1 (en) 1997-04-04 2005-05-10 Monsanto Company Hydrolyzable delivery system using cross-linked polymeric resins as vehicles
WO1998044951A2 (en) * 1997-04-04 1998-10-15 Monsanto Company Hydrolysable delivery system using cross-linked polymeric resins as vehicles
WO1998044952A1 (en) 1997-04-04 1998-10-15 Monsanto Company pH-SELECTIVE DELIVERY SYSTEM USING CROSS-LINKED POLYMERIC RESINS AS VEHICLES
FR2766709B1 (fr) * 1997-07-31 2000-04-07 Dominique Cingotti Procede pour la preparation d'un extrait de principes actifs sous forme de microgranules a base de fibres alimentaires entierement solubles destines a differentes formes galeniques
IT1298574B1 (it) * 1998-02-06 2000-01-12 Vectorpharma Int Composizioni farmaceutiche in forma di microparticelle a base polimerica ottenute mediante estrusione e sferonizzazione
UA65607C2 (uk) 1998-03-04 2004-04-15 Орто-Макнейл Фармацевтикал, Інк. Фармацевтична композиція (варіанти) та спосіб її приготування
US6048736A (en) * 1998-04-29 2000-04-11 Kosak; Kenneth M. Cyclodextrin polymers for carrying and releasing drugs
US6509323B1 (en) 1998-07-01 2003-01-21 California Institute Of Technology Linear cyclodextrin copolymers
US7091192B1 (en) 1998-07-01 2006-08-15 California Institute Of Technology Linear cyclodextrin copolymers
FR2785539B1 (fr) * 1998-11-06 2004-04-09 Prographarm Laboratoires Particules enrobees d'ibuprofene cristallin granule
FR2792528A1 (fr) * 1999-04-22 2000-10-27 Ethypharm Lab Prod Ethiques Microgranules de ketoprofene, procede de preparation et compositions pharmaceutiques
EP1185251A1 (en) * 1999-05-24 2002-03-13 Purepac Pharmaceutical Co. A pharmaceutical composition containing an active agent that is maintained in solid amorphous form and method of making the same
US6555139B2 (en) 1999-06-28 2003-04-29 Wockhardt Europe Limited Preparation of micron-size pharmaceutical particles by microfluidization
US6245913B1 (en) 1999-06-30 2001-06-12 Wockhardt Europe Limited Synthetic procedure for 5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridinyl)-methylthio]-IH-benzimidazole hydrochloride and its conversion to omeprazole
HUP0301333A3 (en) * 1999-12-06 2005-06-28 Penwest Pharmaceuticals Co Sea Pharmaceutical superdisintegrant, process for its preparation and its use
US7108866B1 (en) 1999-12-10 2006-09-19 Biovall Laboratories International Srl Chronotherapeutic diltiazem formulations and the administration thereof
US20060153914A1 (en) * 1999-12-10 2006-07-13 Biovail Laboratories International S.R.L. Chronotherapeutic diltiazem formulations and the administration thereof
MXPA03008292A (es) * 2001-03-13 2003-12-11 Penwest Pharmaceuticals Co Formas de dosificacion cronoterapeuticas que contienen glucocorticosteroides.
KR20010069756A (ko) * 2001-05-08 2001-07-25 유형선 소염진통제인 아세메타신을 함유하며 장관내 특히대장에서의 약물 방출 속도가 조절되는 약물 전달 체계에대한 약제학적 경구용 조성물 및 그에 대한 제조방법
EP1269994A3 (en) * 2001-06-22 2003-02-12 Pfizer Products Inc. Pharmaceutical compositions comprising drug and concentration-enhancing polymers
EP1414414B1 (en) * 2001-06-29 2007-11-07 Eurand Pharmaceuticals Ltd. Process of thermodynamical activation of water-insoluble drugs loaded into cross-linked polymers
DE60205491T2 (de) * 2001-06-29 2006-06-01 Eurand Pharmaceuticals Ltd. Verfahren zur arzneimittelaktivierung mittels schwingmühle
US7060498B1 (en) 2001-11-28 2006-06-13 Genta Salus Llc Polycationic water soluble copolymer and method for transferring polyanionic macromolecules across biological barriers
JP3966459B2 (ja) 2002-05-23 2007-08-29 株式会社日立製作所 ストレージ機器管理方法、システム、およびプログラム
MX367615B (es) 2002-09-06 2019-08-28 Cerulean Pharma Inc Polimeros a base de ciclodextrina para el suministro de agentes terapeuticos.
DE10247037A1 (de) 2002-10-09 2004-04-22 Abbott Gmbh & Co. Kg Herstellung von festen Dosierungsformen unter Verwendung eines vernetzten nichtthermoplastischen Trägers
US20040132771A1 (en) * 2002-12-20 2004-07-08 Pfizer Inc Compositions of choleseteryl ester transfer protein inhibitors and HMG-CoA reductase inhibitors
RU2343913C2 (ru) * 2003-03-31 2009-01-20 Плива-Лахема А.С. Фармацевтическая композиция, содержащая комплекс платины в качестве активного вещества, и способ ее получения
NZ545921A (en) * 2003-09-19 2009-09-25 Penwest Pharmaceuticals Co Delayed released dosage forms
JP2007519608A (ja) * 2003-09-19 2007-07-19 ペンウェスト ファーマシューティカルズ カンパニー 時間治療用剤形
US7387793B2 (en) 2003-11-14 2008-06-17 Eurand, Inc. Modified release dosage forms of skeletal muscle relaxants
JP2008507508A (ja) * 2004-07-22 2008-03-13 株式會社アモーレパシフィック トピラメート徐放性製剤及びその製造方法
US20070036859A1 (en) * 2005-08-11 2007-02-15 Perry Ronald L Sustained release antihistamine and decongestant composition
WO2007096902A2 (en) * 2006-02-23 2007-08-30 Lupin Limited Solid oral dosage forms of griseofulvin
CN102846585A (zh) 2006-03-28 2013-01-02 杰佛林制药公司 低剂量的双氯芬酸和β-环糊精的制剂
US20080102128A1 (en) * 2006-07-28 2008-05-01 Flamel Technologies, Inc. Modified-release microparticles based on amphiphilic copolymer and on active principles(s) and pharmaceutical formulations comprising them
WO2008062437A2 (en) * 2006-09-01 2008-05-29 Usv Limited Process for the preparation of sevelamer hydrochloride and formulation thereof
US7964182B2 (en) * 2006-09-01 2011-06-21 USV, Ltd Pharmaceutical compositions comprising phosphate-binding polymer
JP2010516625A (ja) 2007-01-24 2010-05-20 インサート セラピューティクス， インコーポレイテッド 制御された薬物送達のためのテザー基を有するポリマー−薬物コンジュゲート
US20100172991A1 (en) * 2007-06-08 2010-07-08 Henry Joseph Horacek Extended Release Formulation and Methods of Treating Adrenergic Dysregulation
JP2010529142A (ja) * 2007-06-08 2010-08-26 アドレネクス・ファーマシューティカルズ，インコーポレイテッド アドレナリン調節異常症を治療する徐放性の製剤および方法
JP2010531357A (ja) * 2007-06-25 2010-09-24 エンサイシブ・ファーマシューティカルズ・インコーポレイテッド Ｎ−（２−アセチル−４，６−ジメチルフェニル）−３−｛［（３，４−ジメチル−５−イソオキサゾリル）アミノ］スルホニル｝−２−チオフェンカルボキサミドの製剤
US20090024570A1 (en) * 2007-07-20 2009-01-22 Oracle Internatonal Corporation User defined query rewrite mechanism
PL2224914T3 (pl) 2007-09-14 2015-11-30 Wockhardt Ltd Kompozycje diacereiny
EP2520284A1 (en) 2007-09-27 2012-11-07 Wockhardt Limited Pharmaceutical compositions of rhein or diacerein
US20100285114A1 (en) * 2007-09-27 2010-11-11 Rahul Dabre Pharmaceutical compositions of rhein or diacerein
AU2013200968B2 (en) * 2007-09-27 2013-11-21 Wockhardt Limited Pharmaceutical compositions of rhein or diacerein
US8946277B2 (en) * 2008-04-18 2015-02-03 Warsaw Orthopedic, Inc. Clonidine formulations in a biodegradable polymer carrier
TWI473610B (zh) * 2008-10-28 2015-02-21 Twi Biotechnology Inc 包含雙醋瑞因（ｄｉａｃｅｒｅｉｎ）之醫藥組合物
KR20110119714A (ko) * 2009-01-22 2011-11-02 유에스브이 리미티드 포스페이트 결합 폴리머를 포함하는 약학적 조성물
JP6220126B2 (ja) * 2009-11-23 2017-10-25 セルリアン・ファーマ・インコーポレイテッド 治療的送達のためのシクロデキストリンに基づく重合体
IE20100799A1 (en) 2010-12-22 2012-08-01 Eurand Pharmaceuticals Ltd Pharmaceutical composites of poorly water soluble drugs and polymers
KR20120135063A (ko) * 2011-06-01 2012-12-12 닛토덴코 가부시키가이샤 입자 제제 및 그 제조 방법
US9452107B2 (en) 2012-04-16 2016-09-27 New Jersey Institute Of Technology Systems and methods for superdisintegrant-based composite particles for dispersion and dissolution of agents
WO2014055493A1 (en) 2012-10-02 2014-04-10 Cerulean Pharma Inc. Methods and systems for polymer precipitation and generation of particles
US8999393B1 (en) 2013-01-09 2015-04-07 Edgemont Pharmaceuticals Llc Sustained release formulations of lorazepam
CA2936748C (en) 2014-10-31 2017-08-08 Purdue Pharma Methods and compositions particularly for treatment of attention deficit disorder
EP3411019A1 (en) * 2016-02-05 2018-12-12 Entrega, Inc. Oral dosage form with drying agent for delivery of active agent
EP3459528B1 (en) * 2017-09-20 2022-11-23 Tillotts Pharma Ag Preparation of solid dosage forms comprising antibodies by solution/suspension layering
US10722473B2 (en) 2018-11-19 2020-07-28 Purdue Pharma L.P. Methods and compositions particularly for treatment of attention deficit disorder

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1218102A (en) 1968-03-15 1971-01-06 Philips Nv Improvements in medicaments comprising drug/ion-exchange resin compounds
DE2643004A1 (de) 1975-09-25 1977-06-16 Mitchell Beazley Encyclopedias Audiovisuelles informationssystem - system zum anordnen und wiederauffinden von informationen
US4221778A (en) 1979-01-08 1980-09-09 Pennwalt Corporation Prolonged release pharmaceutical preparations
HU189534B (en) 1981-09-09 1986-07-28 Chinoin Rt.,Hu Process for producing new tablets containing cyclodextrin polymer as desintegrator
DE3270785D1 (en) 1981-10-29 1986-05-28 Bayer Ag Process for preparing solid fast-releasing drug formulations of dihydropyridines
EP0147780A3 (en) 1984-01-03 1987-03-11 Merck & Co. Inc. Drug delivery device
GB8403359D0 (en) 1984-02-08 1984-03-14 Erba Farmitalia Pharmaceutical compositions
CA1236023A (en) 1984-07-18 1988-05-03 Yegnaswami Raghunathan Controlled release pharmaceutical preparations
IE63321B1 (en) * 1986-02-03 1995-04-05 Elan Corp Plc Drug delivery system
EP0250374B1 (en) * 1986-06-17 1991-05-02 RECORDATI INDUSTRIA CHIMICA E FARMACEUTICA S.p.a. Therapeutic system for controlled release of drugs
JPH0819004B2 (ja) 1986-12-26 1996-02-28 日清製粉株式会社 徐放性医薬製剤
GB8705083D0 (en) * 1987-03-04 1987-04-08 Euro Celtique Sa Spheroids
US4894239A (en) 1987-06-02 1990-01-16 Takeda Chemical Industries, Ltd. Sustained-release preparation and production thereof
US4795644A (en) 1987-08-03 1989-01-03 Merck & Co., Inc. Device for pH independent release of drugs through the Donnan-like influence of charged insoluble resins
IE63242B1 (en) * 1988-06-24 1995-04-05 Abbott Lab Pharmaceutical granules and tablets made therefrom

Also Published As

Publication number Publication date
JP3240387B2 (ja) 2001-12-17
ATE114242T1 (de) 1994-12-15
US5275824A (en) 1994-01-04
HUT59588A (en) 1992-06-29
KR0175935B1 (ko) 1999-03-20
DE69105222T2 (de) 1995-04-06
PL289322A1 (en) 1992-05-04
HU910707D0 (en) 1991-09-30
CA2037410C (en) 2001-09-04
DE69105222D1 (de) 1995-01-05
EP0446753B1 (en) 1994-11-23
JPH0769927A (ja) 1995-03-14
EP0446753A1 (en) 1991-09-18
CA2037410A1 (en) 1991-09-07
YU34491A (sh) 1994-06-10
ES2067068T3 (es) 1995-03-16
IT9019571A1 (it) 1991-09-06
KR910016320A (ko) 1991-11-05
IT1241417B (it) 1994-01-14
RU2067859C1 (ru) 1996-10-20

Similar Documents

Publication Publication Date Title
IT9019571A0 (it) Composizioni terapeutiche a rilascio controllato di farmaci supportatisu polimeri reticolati e rivestiti con film polimerici,e loro processodi preparazione
EP0640337A3 (en) Controlled release-initiation and controlled release-rate pharmaceutical composition
MX9100213A (es) Peliculas de polimero autosoportadas y proceso para su fabricacion
DE69222421D1 (de) Polymer folie
ES2051698T3 (es) Granulos destinados a permanecer en el estomago.
DE4293170T1 (de) Antithromboseharz, Antithromboseröhrchen, Antithrombosefilm und Antithromboseüberzug
NO904203D0 (no) Fremgangsmaate for fremstilling av klebrige polymerer.
DK235989A (da) Polymer folie
CA2046830A1 (en) Drug delivery system involving inter-action between protein or polypeptide and hydrophobic biodegradable polymer
FI901492A0 (fi) Hydrofiiliset paisumiskykyiset oksaspolymeerit, niiden valmistus ja käyttö
DE69127805D1 (de) Cyclodextrin-polymer sowie daraus hergestellter cyclodextrin-film
IL93780A (en) Pyrotechnic materials comprising metal coated polymer films
FI932603A0 (fi) Regiospecifika katalysatorer foer framstaellning av epoxisiloxanmonomerer och -polymerer
AU647518B2 (en) Coating base for pharmaceutical film and production thereof
DE69401736D1 (de) Vernetzbare Polymertrennmittelbeschichtungszusammensetzung
DE59103764D1 (de) Mit Copolymerfilmen beschichteter Betonstein.
DE69107072D1 (de) Vernetzte leitende polymere und diese enthaltende antistatische beschichtungen.
ITTO991137A0 (it) Monomeri di reticolazione per fotoresist e procedimento per la prepara zione di polimeri fotoresist utilizzanti tali monomeri.
DE68921263D1 (de) Beschichtete Filme.
NO934066D0 (no) Middel til hindring av polymeravleiring
AU7302091A (en) Polymerization process and the polymers thereof
FI932640A0 (fi) Nya rodiuminnehaollande selektiva katalyter foer en syntes av epoxisiloxan/epoxisilikonmonomerer och -polymerer
ITMI931815A0 (it) Manufatti in film cast costituiti da polimeri propilenici
AU3640689A (en) Heterogeneous interpenetrating polymer networks for the controlled release of drugs
IT9021568A0 (it) Dispositivo per controllare lo spessore radiale di estrusione di polimeri termoplastici

Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19950930