IT7927856A0 - Pirrolo oppure pirido aperta par.quadra 2,1-c chiusa par. quadra aperta par. quadra 1,4 chiusa par.quadra tiazine otiazepine. - Google Patents

Pirrolo oppure pirido aperta par.quadra 2,1-c chiusa par. quadra aperta par. quadra 1,4 chiusa par.quadra tiazine otiazepine.

Info

Publication number: IT7927856A0
Authority: IT; Italy
Prior art keywords: par; quadra; closed; open square; othiazepines
Prior art date: 1978-12-07

Application number

IT7927856A

Other languages

English (en)

Other versions

IT1127282B (it

Inventor

Miguel A Ondetti

Original Assignee

Squibb & Sons Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-12-07

Filing date

1979-12-04

Publication date

1979-12-04

1979-12-04 Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc

1979-12-04 Publication of IT7927856A0 publication Critical patent/IT7927856A0/it

1986-05-21 Application granted granted Critical

1986-05-21 Publication of IT1127282B publication Critical patent/IT1127282B/it

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Cardiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Heart & Thoracic Surgery (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Peptides Or Proteins (AREA)
Hydrogenated Pyridines (AREA)
Pyrrole Compounds (AREA)

IT27856/79A 1978-12-07 1979-12-04 Pirrolo oppure pirido aperta par.quadra 2,1-c chiusa par.quadra aperta par.quadra 1,4 chiusa par.quadra tiazine otiazepine IT1127282B (it)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US05/967,335 US4225495A (en)	1978-12-07	1978-12-07	Pyrrolo or pyrido [2,1-c][1,4] thiazines or thiazepines

Publications (2)

Publication Number	Publication Date
IT7927856A0 true IT7927856A0 (it)	1979-12-04
IT1127282B IT1127282B (it)	1986-05-21

Family

ID=25512648

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IT27856/79A IT1127282B (it)	1978-12-07	1979-12-04	Pirrolo oppure pirido aperta par.quadra 2,1-c chiusa par.quadra aperta par.quadra 1,4 chiusa par.quadra tiazine otiazepine

Country Status (18)

Country	Link
US (1)	US4225495A (it)
JP (1)	JPS5581886A (it)
AU (1)	AU532228B2 (it)
BE (1)	BE880480A (it)
CA (1)	CA1126728A (it)
CH (1)	CH643268A5 (it)
DE (1)	DE2949179A1 (it)
DK (1)	DK520279A (it)
FR (2)	FR2443468A1 (it)
GB (1)	GB2036743B (it)
HU (2)	HU179342B (it)
IE (1)	IE49123B1 (it)
IT (1)	IT1127282B (it)
LU (1)	LU81956A1 (it)
NL (1)	NL7908618A (it)
NO (1)	NO793983L (it)
SE (2)	SE446737B (it)
ZA (1)	ZA796288B (it)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4692458A (en) *	1980-03-05	1987-09-08	University Of Miami	Anti-hypertensive agents
US4385180A (en) *	1980-07-01	1983-05-24	American Home Products Corporation	10,10a-Dihydro-1H-thiozino[4,3-a,]-indole-1,4(3H)-diones
US4352753A (en) *	1980-08-11	1982-10-05	American Home Products Corporation	3-[[(2,3-Dihydro-1H-indol-2-yl)carbonyl]thio]propanoic (and acetic) acids as intermediates
US4415496A (en) *	1981-03-23	1983-11-15	Merck & Co., Inc.	Bicyclic lactams
US4661479A (en) *	1982-02-19	1987-04-28	Merck And Co., Inc.	Bicyclic lactams as antihypertensives
US4617301A (en) *	1983-06-22	1986-10-14	Merck & Co., Inc.	Sulfoxide and sulfone derivatives of bicyclic lactams as antihypertensives
US5508272A (en) *	1993-06-15	1996-04-16	Bristol-Myers Squibb Company	Compounds containing a fused bicycle ring and processes therefor
US5616775A (en) *	1994-05-05	1997-04-01	Bristol-Myers Squibb Co.	Process for preparing homocystein analogs useful as intermediates for compounds containing a fused bicyclic ring
US5587375A (en) *	1995-02-17	1996-12-24	Bristol-Myers Squibb Company	Azepinone compounds useful in the inhibition of ACE and NEP
US5877313A (en) *	1995-05-17	1999-03-02	Bristol-Myers Squibb	Benzo-fused azepinone and piperidinone compounds useful in the inhibition of ACE and NEP
US5635504A (en) *	1995-06-07	1997-06-03	Bristol-Myers Squibb Co.	Diazepine containing dual action inhibitors
US5650408A (en) *	1995-06-07	1997-07-22	Karanewsky; Donald S.	Thiazolo benzazepine containing dual action inhibitors

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2891000A (en) *	1953-09-23	1959-06-16	Exxon Research Engineering Co	Process for feeding heavy oils into conversion systems
US4105776A (en) *	1976-06-21	1978-08-08	E. R. Squibb & Sons, Inc.	Proline derivatives and related compounds
US4046889A (en) *	1976-02-13	1977-09-06	E. R. Squibb & Sons, Inc.	Azetidine-2-carboxylic acid derivatives
US4154935A (en) *	1978-02-21	1979-05-15	E. R. Squibb & Sons, Inc.	Halogen substituted mercaptoacylamino acids
JPS5576888A (en) *	1978-12-04	1980-06-10	Yoshitomi Pharmaceut Ind Ltd	Bicyclic hetero compound and its preparation

1978
- 1978-12-07 US US05/967,335 patent/US4225495A/en not_active Expired - Lifetime
1979
- 1979-11-20 ZA ZA00796288A patent/ZA796288B/xx unknown
- 1979-11-20 CA CA340,201A patent/CA1126728A/en not_active Expired
- 1979-11-23 AU AU53144/79A patent/AU532228B2/en not_active Expired
- 1979-11-28 NL NL7908618A patent/NL7908618A/nl not_active Application Discontinuation
- 1979-11-28 FR FR7929249A patent/FR2443468A1/fr active Granted
- 1979-11-29 GB GB7941320A patent/GB2036743B/en not_active Expired
- 1979-12-04 IT IT27856/79A patent/IT1127282B/it active
- 1979-12-04 IE IE2329/79A patent/IE49123B1/en not_active IP Right Cessation
- 1979-12-05 LU LU81956A patent/LU81956A1/fr unknown
- 1979-12-06 NO NO793983A patent/NO793983L/no unknown
- 1979-12-06 BE BE0/198464A patent/BE880480A/fr not_active IP Right Cessation
- 1979-12-06 HU HU79SU1042A patent/HU179342B/hu unknown
- 1979-12-06 DE DE19792949179 patent/DE2949179A1/de not_active Ceased
- 1979-12-06 DK DK520279A patent/DK520279A/da not_active Application Discontinuation
- 1979-12-06 HU HU812891A patent/HU182755B/hu unknown
- 1979-12-06 SE SE7910072A patent/SE446737B/sv not_active IP Right Cessation
- 1979-12-06 CH CH1083879A patent/CH643268A5/de not_active IP Right Cessation
- 1979-12-07 JP JP15971079A patent/JPS5581886A/ja active Pending
1980
- 1980-03-19 FR FR8006146A patent/FR2445318A1/fr active Granted
1984
- 1984-10-12 SE SE8405123A patent/SE452458B/sv not_active IP Right Cessation

Also Published As

Publication number	Publication date
DE2949179A1 (de)	1980-06-26
FR2445318B1 (it)	1983-04-22
NO793983L (no)	1980-06-10
JPS5581886A (en)	1980-06-20
SE8405123L (sv)	1984-10-12
AU532228B2 (en)	1983-09-22
FR2443468B1 (it)	1983-04-22
NL7908618A (nl)	1980-06-10
IE49123B1 (en)	1985-08-07
GB2036743A (en)	1980-07-02
IE792329L (en)	1980-06-07
ZA796288B (en)	1980-11-26
HU182755B (en)	1984-03-28
IT1127282B (it)	1986-05-21
CH643268A5 (de)	1984-05-30
SE452458B (sv)	1987-11-30
BE880480A (fr)	1980-06-06
FR2445318A1 (fr)	1980-07-25
US4225495A (en)	1980-09-30
SE446737B (sv)	1986-10-06
CA1126728A (en)	1982-06-29
HU179342B (en)	1982-10-28
DK520279A (da)	1980-06-08
FR2443468A1 (fr)	1980-07-04
AU5314479A (en)	1980-06-12
SE8405123D0 (sv)	1984-10-12
SE7910072L (sv)	1980-06-08
LU81956A1 (fr)	1980-04-22
GB2036743B (en)	1982-11-24

Publication	Publication Date	Title
NO793126L (no)	1980-04-01	Lukkeanordning.
NO791071L (no)	1979-10-02	Lukkeinnretning.
ES243021Y (es)	1980-06-16	Disposicion de cierre perfeccionada.
IT7927856A0 (it)	1979-12-04	Pirrolo oppure pirido aperta par.quadra 2,1-c chiusa par. quadra aperta par. quadra 1,4 chiusa par.quadra tiazine otiazepine.
ES247048Y (es)	1980-09-16	Capsula de cierre para frascos y similares.
NO793820L (no)	1980-05-28	Lukkeanordning.
NL7901744A (nl)	1979-12-11	Sluitdop.
IT7924171A0 (it)	1979-07-06	Imidazoliletossi-derivati di pirazol-aperta parentesi quadra 3,4-b chiusa parentesi quadra-piridin-5-metanoli.
IT7824705A0 (it)	1978-06-19	Esaidrobenzopirano aperta parentesi quadra 3,2-c chiusa parentesi quadra piridine sostituite.
NL172711C (nl)	1983-10-03	Geheel gesloten schakelinstallatie-eenheid.
IT8222005A0 (it)	1982-06-23	Pirrolo par. aperta quadrata 2,1-bpar. chiusa quadrata chinazoline e pirido par. aperta quadrata 2,1-bpar. chiusa quadrata chinazoline sostituite e processo per loro preparazione.
IT1098015B (it)	1985-08-31	Nuovi 4,5,6,7,-tetraidroimidazo-aperta par.quadrata 4,5-c chiusa par.quadrata-piridin-derivati
NL7900030A (nl)	1979-07-10	Afsluiting.
IT1097289B (it)	1985-08-31	Benz aperta par.quadrata f chiusa par.quadrata isoindoline,loro preparazione e loro impiego
NL7901134A (nl)	1979-09-04	Sluitinrichting.
ES236117Y (es)	1979-04-01	Puerta de cuarterones, perfeccionada.
ES243657Y (es)	1980-04-01	Amortiguador de puerta.
ES235755Y (es)	1978-11-01	Reja de cierre perfeccionada.
IT8020762A0 (it)	1980-03-19	Dispositivo di chiusura idraulico.
IT7826436A0 (it)	1978-08-03	Derivati benzimidazo aperta par.quadrata 1,2-b chiusa par. quadrata ossazinici attivi sul sistema nervoso centrale.
ES234142Y (es)	1979-02-01	Puerta ligera perfeccionada.
IT7824665A0 (it)	1978-06-16	Esaidro-1-idrossi-9-idrossimetil-6h-dibenzo aperta parentesi quadra b,d chiusa parentesi quadra pirani sostituiti in posizione 3 come agenti analgesici.
ES246407Y (es)	1980-12-16	Cierre electromecanico automatico,perfeccionado
ES233903Y (es)	1978-08-16	Candado perfeccionado.
ES242308Y (es)	1979-11-16	Cierre corredizo perfeccionado.

Legal Events

Date	Code	Title	Description
1999-10-27	TA	Fee payment date (situation as of event date), data collected since 19931001	Effective date: 19961227