IT7927856A0 - PYRROLE OR PYRIDO OPEN SQUARE PAR. 2.1-C CLOSED PAR. OPEN SQUARE PAR. QUADRA 1.4 CLOSED PAR.QUADRA THIAZINES OTHIAZEPINES. - Google Patents

PYRROLE OR PYRIDO OPEN SQUARE PAR. 2.1-C CLOSED PAR. OPEN SQUARE PAR. QUADRA 1.4 CLOSED PAR.QUADRA THIAZINES OTHIAZEPINES.

Info

Publication number: IT7927856A0
Authority: IT; Italy
Prior art keywords: par; quadra; closed; open square; othiazepines
Prior art date: 1978-12-07

Application number

IT7927856A

Other languages

Italian (it)

Other versions

IT1127282B (en

Inventor

Miguel A Ondetti

Original Assignee

Squibb & Sons Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-12-07

Filing date

1979-12-04

Publication date

1979-12-04

1979-12-04 Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc

1979-12-04 Publication of IT7927856A0 publication Critical patent/IT7927856A0/en

1986-05-21 Application granted granted Critical

1986-05-21 Publication of IT1127282B publication Critical patent/IT1127282B/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Peptides Or Proteins (AREA)
Pyrrole Compounds (AREA)
Hydrogenated Pyridines (AREA)

IT27856/79A 1978-12-07 1979-12-04 PIRROLO OR PIRIDO OPEN PAR.QUADRA 2,1-C CLOSED PAR.QUADRA OPEN PAR.QUADRA 1,4 CLOSED PARQUADRA TIAZINE OTIAZEPINE IT1127282B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US05/967,335 US4225495A (en)	1978-12-07	1978-12-07	Pyrrolo or pyrido [2,1-c][1,4] thiazines or thiazepines

Publications (2)

Publication Number	Publication Date
IT7927856A0 true IT7927856A0 (en)	1979-12-04
IT1127282B IT1127282B (en)	1986-05-21

Family

ID=25512648

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IT27856/79A IT1127282B (en)	1978-12-07	1979-12-04	PIRROLO OR PIRIDO OPEN PAR.QUADRA 2,1-C CLOSED PAR.QUADRA OPEN PAR.QUADRA 1,4 CLOSED PARQUADRA TIAZINE OTIAZEPINE

Country Status (18)

Country	Link
US (1)	US4225495A (en)
JP (1)	JPS5581886A (en)
AU (1)	AU532228B2 (en)
BE (1)	BE880480A (en)
CA (1)	CA1126728A (en)
CH (1)	CH643268A5 (en)
DE (1)	DE2949179A1 (en)
DK (1)	DK520279A (en)
FR (2)	FR2443468A1 (en)
GB (1)	GB2036743B (en)
HU (2)	HU182755B (en)
IE (1)	IE49123B1 (en)
IT (1)	IT1127282B (en)
LU (1)	LU81956A1 (en)
NL (1)	NL7908618A (en)
NO (1)	NO793983L (en)
SE (2)	SE446737B (en)
ZA (1)	ZA796288B (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4692458A (en) *	1980-03-05	1987-09-08	University Of Miami	Anti-hypertensive agents
US4385180A (en) *	1980-07-01	1983-05-24	American Home Products Corporation	10,10a-Dihydro-1H-thiozino[4,3-a,]-indole-1,4(3H)-diones
US4352753A (en) *	1980-08-11	1982-10-05	American Home Products Corporation	3-[[(2,3-Dihydro-1H-indol-2-yl)carbonyl]thio]propanoic (and acetic) acids as intermediates
US4415496A (en) *	1981-03-23	1983-11-15	Merck & Co., Inc.	Bicyclic lactams
US4661479A (en) *	1982-02-19	1987-04-28	Merck And Co., Inc.	Bicyclic lactams as antihypertensives
US4617301A (en) *	1983-06-22	1986-10-14	Merck & Co., Inc.	Sulfoxide and sulfone derivatives of bicyclic lactams as antihypertensives
US5508272A (en) *	1993-06-15	1996-04-16	Bristol-Myers Squibb Company	Compounds containing a fused bicycle ring and processes therefor
US5616775A (en) *	1994-05-05	1997-04-01	Bristol-Myers Squibb Co.	Process for preparing homocystein analogs useful as intermediates for compounds containing a fused bicyclic ring
US5587375A (en) *	1995-02-17	1996-12-24	Bristol-Myers Squibb Company	Azepinone compounds useful in the inhibition of ACE and NEP
US5877313A (en)	1995-05-17	1999-03-02	Bristol-Myers Squibb	Benzo-fused azepinone and piperidinone compounds useful in the inhibition of ACE and NEP
US5635504A (en) *	1995-06-07	1997-06-03	Bristol-Myers Squibb Co.	Diazepine containing dual action inhibitors
US5650408A (en) *	1995-06-07	1997-07-22	Karanewsky; Donald S.	Thiazolo benzazepine containing dual action inhibitors

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2891000A (en) *	1953-09-23	1959-06-16	Exxon Research Engineering Co	Process for feeding heavy oils into conversion systems
US4105776A (en) *	1976-06-21	1978-08-08	E. R. Squibb & Sons, Inc.	Proline derivatives and related compounds
US4046889A (en) *	1976-02-13	1977-09-06	E. R. Squibb & Sons, Inc.	Azetidine-2-carboxylic acid derivatives
US4154935A (en) *	1978-02-21	1979-05-15	E. R. Squibb & Sons, Inc.	Halogen substituted mercaptoacylamino acids
JPS5576888A (en) *	1978-12-04	1980-06-10	Yoshitomi Pharmaceut Ind Ltd	Bicyclic hetero compound and its preparation

1978
- 1978-12-07 US US05/967,335 patent/US4225495A/en not_active Expired - Lifetime
1979
- 1979-11-20 CA CA340,201A patent/CA1126728A/en not_active Expired
- 1979-11-20 ZA ZA00796288A patent/ZA796288B/en unknown
- 1979-11-23 AU AU53144/79A patent/AU532228B2/en not_active Expired
- 1979-11-28 FR FR7929249A patent/FR2443468A1/en active Granted
- 1979-11-28 NL NL7908618A patent/NL7908618A/en not_active Application Discontinuation
- 1979-11-29 GB GB7941320A patent/GB2036743B/en not_active Expired
- 1979-12-04 IT IT27856/79A patent/IT1127282B/en active
- 1979-12-04 IE IE2329/79A patent/IE49123B1/en not_active IP Right Cessation
- 1979-12-05 LU LU81956A patent/LU81956A1/en unknown
- 1979-12-06 BE BE0/198464A patent/BE880480A/en not_active IP Right Cessation
- 1979-12-06 DK DK520279A patent/DK520279A/en not_active Application Discontinuation
- 1979-12-06 CH CH1083879A patent/CH643268A5/en not_active IP Right Cessation
- 1979-12-06 NO NO793983A patent/NO793983L/en unknown
- 1979-12-06 HU HU812891A patent/HU182755B/en unknown
- 1979-12-06 HU HU79SU1042A patent/HU179342B/en unknown
- 1979-12-06 DE DE19792949179 patent/DE2949179A1/en not_active Ceased
- 1979-12-06 SE SE7910072A patent/SE446737B/en not_active IP Right Cessation
- 1979-12-07 JP JP15971079A patent/JPS5581886A/en active Pending
1980
- 1980-03-19 FR FR8006146A patent/FR2445318A1/en active Granted
1984
- 1984-10-12 SE SE8405123A patent/SE452458B/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
SE452458B (en)	1987-11-30
DE2949179A1 (en)	1980-06-26
IT1127282B (en)	1986-05-21
GB2036743B (en)	1982-11-24
HU182755B (en)	1984-03-28
IE792329L (en)	1980-06-07
SE7910072L (en)	1980-06-08
FR2443468A1 (en)	1980-07-04
AU5314479A (en)	1980-06-12
ZA796288B (en)	1980-11-26
FR2445318B1 (en)	1983-04-22
DK520279A (en)	1980-06-08
SE8405123L (en)	1984-10-12
US4225495A (en)	1980-09-30
GB2036743A (en)	1980-07-02
SE446737B (en)	1986-10-06
CA1126728A (en)	1982-06-29
CH643268A5 (en)	1984-05-30
AU532228B2 (en)	1983-09-22
NL7908618A (en)	1980-06-10
FR2443468B1 (en)	1983-04-22
SE8405123D0 (en)	1984-10-12
HU179342B (en)	1982-10-28
LU81956A1 (en)	1980-04-22
BE880480A (en)	1980-06-06
JPS5581886A (en)	1980-06-20
FR2445318A1 (en)	1980-07-25
IE49123B1 (en)	1985-08-07
NO793983L (en)	1980-06-10

Publication	Publication Date	Title
NO793126L (en)	1980-04-01	CLOSING DEVICE.
NO791071L (en)	1979-10-02	CLOSING DEVICE.
ES243021Y (en)	1980-06-16	PERFECTED CLOSING PROVISION.
IT7927856A0 (en)	1979-12-04	PYRROLE OR PYRIDO OPEN SQUARE PAR. 2.1-C CLOSED PAR. OPEN SQUARE PAR. QUADRA 1.4 CLOSED PAR.QUADRA THIAZINES OTHIAZEPINES.
ES247048Y (en)	1980-09-16	CLOSING CAPSULE FOR JARS AND THE LIKE.
NO793820L (en)	1980-05-28	CLOSING DEVICE.
NL7901744A (en)	1979-12-11	CLOSING CAP.
IT7924171A0 (en)	1979-07-06	IMIDAZOLILETHOXY-PYRAZOL DERIVATIVES-OPEN SQUARE BRACKET 3,4-B CLOSED SQUARE BRACKET-PYRIDIN-5-METHANOLS.
IT7824705A0 (en)	1978-06-19	HEXHYDROBENZOPYRAN OPEN SQUARE BRACKET 3,2-C CLOSED SQUARE BRACKET SUBSTITUTED PYRIDINES.
NL172711B (en)	1983-05-02	COMPLETELY CLOSED SWITCHING UNIT.
IT8222005A0 (en)	1982-06-23	PIRROLO PAR. OPEN SQUARE 2.1-BPAR. SQUARE CLOSE CHINAZOLINE AND PYRIDO PAR. OPEN SQUARE 2.1-BPAR. CLOSED SQUARE SUBSTITUTED CHINAZOLINES AND PROCESS FOR THEIR PREPARATION.
IT1098015B (en)	1985-08-31	NEW 4,5,6,7, -TETRAIDROIMIDAZO-OPEN SQUARE PAR 4,5-C CLOSED SQUARE PAR-PIRIDIN-DERIVATIVES
NL7900030A (en)	1979-07-10	CLOSING.
IT1097289B (en)	1985-08-31	BENZ OPEN SQUARE PAR. F CLOSED SQUARE PAR. ISOINDOLINE, THEIR PREPARATION AND USE
NL7901134A (en)	1979-09-04	CLOSING DEVICE.
ES236117Y (en)	1979-04-01	QUARTERLY DOOR, PERFECTED.
ES243657Y (en)	1980-04-01	DOOR DAMPER.
IT8020762A0 (en)	1980-03-19	HYDRAULIC CLOSING DEVICE.
IT7826436A0 (en)	1978-08-03	BENZIMIDAZO DERIVATIVES OPEN SQUARE PAR. 1.2-B CLOSED PAR. SQUARE OXAZINES ACTIVE ON THE CENTRAL NERVOUS SYSTEM.
ES234142Y (en)	1979-02-01	PERFECTED LIGHT DOOR.
IT7824665A0 (en)	1978-06-16	HEXHYDRO-1-HYDROXY-9-HYDROXYMETHYL-6H-DIBENZO OPEN SQUARE BRACKET B,D CLOSED SQUARE BRACKET PIRANES SUBSTITUTED IN POSITION 3 AS ANALGESIC AGENTS.
ES233903Y (en)	1978-08-16	PERFECTED PADLOCK.
ES242308Y (en)	1979-11-16	PERFECTED SLIDING CLOSURE.
ES236909Y (en)	1979-04-16	PERFECTED MOTORIZED VALVE.
ES233545Y (en)	1978-07-16	PERFECTED SLIDING DOOR SLIDING.

Legal Events

Date	Code	Title	Description
1999-10-27	TA	Fee payment date (situation as of event date), data collected since 19931001	Effective date: 19961227