IT1317741B1 - Metodo per la preparazione di 5-cianoftalide. - Google Patents

Metodo per la preparazione di 5-cianoftalide.

Info

Publication number: IT1317741B1
Authority: IT; Italy
Prior art keywords: cyanophalide; preparation
Prior art date: 1999-01-29

Application number

IT2000MI000112A

Other languages

English (en)

Inventor

Beat Weber

Original Assignee

Lundbeck & Co As H

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-01-29

Filing date

2000-01-27

Publication date

2003-07-15

2000-01-27 Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H

2000-01-27 Publication of ITMI20000112A0 publication Critical patent/ITMI20000112A0/it

2001-07-27 Publication of ITMI20000112A1 publication Critical patent/ITMI20000112A1/it

2003-07-15 Application granted granted Critical

2003-07-15 Publication of IT1317741B1 publication Critical patent/IT1317741B1/it

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
- C07D307/88—Benzo [c] furans; Hydrogenated benzo [c] furans with one oxygen atom directly attached in position 1 or 3

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Furan Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Indole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

IT2000MI000112A 1999-01-29 2000-01-27 Metodo per la preparazione di 5-cianoftalide. IT1317741B1 (it)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DKPA199900128		1999-01-29

Publications (3)

Publication Number	Publication Date
ITMI20000112A0 ITMI20000112A0 (it)	2000-01-27
ITMI20000112A1 ITMI20000112A1 (it)	2001-07-27
IT1317741B1 true IT1317741B1 (it)	2003-07-15

Family

ID=8090069

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IT2000MI000112A IT1317741B1 (it)	1999-01-29	2000-01-27	Metodo per la preparazione di 5-cianoftalide.

Country Status (31)

Country	Link
US (1)	US6441201B1 (it)
EP (1)	EP1150966B1 (it)
JP (1)	JP2002535397A (it)
KR (1)	KR100430327B1 (it)
CN (1)	CN1158271C (it)
AR (1)	AR022329A1 (it)
AT (1)	ATE222900T1 (it)
AU (1)	AU763666B2 (it)
BG (1)	BG64924B1 (it)
BR (1)	BR0008978A (it)
CA (1)	CA2361395C (it)
CZ (1)	CZ300257B6 (it)
DE (1)	DE60000364T2 (it)
DK (1)	DK1150966T3 (it)
EA (1)	EA003257B1 (it)
ES (1)	ES2180508T3 (it)
HK (1)	HK1044342B (it)
HU (1)	HUP0104976A3 (it)
IL (2)	IL144114A0 (it)
IS (1)	IS2223B (it)
IT (1)	IT1317741B1 (it)
NO (1)	NO326532B1 (it)
NZ (1)	NZ512775A (it)
PL (1)	PL198385B1 (it)
PT (1)	PT1150966E (it)
SI (1)	SI1150966T1 (it)
SK (1)	SK284367B6 (it)
TR (1)	TR200102135T2 (it)
UA (1)	UA70987C2 (it)
WO (1)	WO2000044738A1 (it)
ZA (1)	ZA200105549B (it)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2000023431A1 (en)	1998-10-20	2000-04-27	H. Lundbeck A/S	Method for the preparation of citalopram
AU764161B2 (en)	1998-12-23	2003-08-14	H. Lundbeck A/S	Method for the preparation of 5-cyanophthalide
HU227473B1 (en)	1999-04-14	2011-07-28	Lundbeck & Co As H	Method for preparation of citalopram
ITMI991579A1 (it)	1999-06-25	2001-01-15	Lundbeck & Co As H	Metodo per la preparazione di citalopram
ITMI991581A1 (it) *	1999-06-25	2001-01-15	Lundbeck & Co As H	Metodo per la preparazione di citalopram
ATE277032T1 (de)	1999-10-25	2004-10-15	Lundbeck & Co As H	Verfahren zur herstellung von citalopram
GB2360281B (en)	1999-10-25	2002-01-16	Lundbeck & Co As H	Method for the preparation of citalopram
AR026063A1 (es)	1999-11-01	2002-12-26	Lundbeck & Co As H	Metodo para la preparacion de 5-carboxiftalida.
CZ20022213A3 (cs)	1999-12-28	2002-09-11	H. Lundbeck A/S	Způsob výroby citalopramu
KR100653141B1 (ko)	1999-12-30	2006-12-01	하. 룬트벡 아크티에 셀스카브	시탈로프람의 제조 방법
AU3033700A (en)	2000-01-14	2001-07-24	H. Lundbeck A/S	Method for the preparation of 5-cyanophthalide
FR2805812A1 (fr)	2000-02-24	2001-09-07	Lundbeck & Co As H	Procede de preparation du citalopram
NL1017417C1 (nl)	2000-03-03	2001-03-16	Lundbeck & Co As H	Werkwijze voor de bereiding van Citalopram.
BR0109176A (pt)	2000-03-13	2003-04-22	Lundbeck & Co As H	Método para preparação de citalopram e composto da fórmula
NL1017500C1 (nl)	2000-03-13	2001-04-26	Lundbeck & Co As H	Werkwijze voor de bereiding van Citalopram.
PL357022A1 (en) *	2000-03-13	2004-07-12	H.Lundbeck A/S	Stepwise alkylation of 5-substituted 1-(4-fluorophenyl)-1,3-dihydroisobenzofurans
BR0109268A (pt)	2000-03-14	2002-12-03	Lundbeck & Co As H	Método de preparação de citalopram, composto e citaplopram
EA200200982A1 (ru) *	2000-03-16	2003-02-27	Х.Лундбекк А/С	Способ получения 5-циано-1-(4-фторфенил)-1,3-дигидроизобензофуранов
AR032455A1 (es)	2000-05-12	2003-11-12	Lundbeck & Co As H	Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
CA2354877C (en) *	2000-08-18	2006-05-02	H. Lundbeck A/S	Method for the preparation of citalopram
ES2228824T3 (es)	2000-12-22	2005-04-16	H. Lundbeck A/S	Metodo de preparacion de citalopram puro.
DE60100016T2 (de)	2000-12-28	2003-04-17	H. Lundbeck A/S, Valby	Verfahren zur herstellung von reinem citalopram
GR1004635B (el) *	2001-08-14	2004-07-14	H@Αlundbeckαa@Sαα	Μεθοδοσαπαρασκευησατησασιταλοπραμης@αα
EP1321464A1 (en) *	2001-12-21	2003-06-25	ICROM S.p.A.	Process for the preparation of 5-cyanophthalide and intermediates useful therein
TWI306846B (en)	2002-08-12	2009-03-01	Lundbeck & Co As H	Method for the separation of intermediates which may be used for the preparation of escitalopram
EP1611118A2 (en)	2003-03-21	2006-01-04	H. Lundbeck A/S	Intermediates for the preparation of citalopram and escitalopram
AU2003223105A1 (en) *	2003-03-24	2004-10-18	Hetero Drugs Limited	Novel crystalline forms of (s)-citalopram oxalate
EP1777221A1 (en) *	2005-10-14	2007-04-25	Adorkem Technology SpA	Process for the preparation of 5-cyanophthalide starting from 5-carboxyphthalide

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1143702A (it)	1965-03-18
GB1526331A (en)	1976-01-14	1978-09-27	Kefalas As	Phthalanes
GB8419963D0 (en) *	1984-08-06	1984-09-12	Lundbeck & Co As H	Intermediate compound and method
GB8814057D0 (en)	1988-06-14	1988-07-20	Lundbeck & Co As H	New enantiomers & their isolation
US5296507A (en)	1990-09-06	1994-03-22	H.Lundbeck A/S	Treatment of cerbrovascular disorders
DE19626659A1 (de)	1996-07-03	1998-01-08	Basf Ag	Verfahren zur Herstellung von Phthaliden
DE19627697A1 (de)	1996-07-10	1998-01-15	Basf Ag	Verfahren zur Herstellung von Phthaliden
JP3526581B2 (ja) *	1997-07-08	2004-05-17	ハー・ルンドベック・アクティーゼルスカブ	シタロプラムの製造方法
UA62985C2 (en) *	1997-11-10	2004-01-15	Lunnbeck As H	A method for the preparation of citalopram
AU738359B2 (en)	1997-11-11	2001-09-13	H. Lundbeck A/S	Method for the preparation of citalopram
WO2000023431A1 (en)	1998-10-20	2000-04-27	H. Lundbeck A/S	Method for the preparation of citalopram
AU764161B2 (en)	1998-12-23	2003-08-14	H. Lundbeck A/S	Method for the preparation of 5-cyanophthalide
HU227473B1 (en)	1999-04-14	2011-07-28	Lundbeck & Co As H	Method for preparation of citalopram
ITMI991579A1 (it)	1999-06-25	2001-01-15	Lundbeck & Co As H	Metodo per la preparazione di citalopram
ITMI991581A1 (it)	1999-06-25	2001-01-15	Lundbeck & Co As H	Metodo per la preparazione di citalopram
GB2360281B (en)	1999-10-25	2002-01-16	Lundbeck & Co As H	Method for the preparation of citalopram
US6310222B1 (en)	1999-11-01	2001-10-30	Sumika Fine Chemicals Co., Ltd.	Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate
IES20010143A2 (en)	2000-02-24	2001-07-25	Lundbeck & Co As H	Method for the preparation of citalopram
FR2805812A1 (fr)	2000-02-24	2001-09-07	Lundbeck & Co As H	Procede de preparation du citalopram
GB0005477D0 (en)	2000-03-07	2000-04-26	Resolution Chemicals Limited	Process for the preparation of citalopram
CA2354877C (en)	2000-08-18	2006-05-02	H. Lundbeck A/S	Method for the preparation of citalopram
ES2228824T3 (es)	2000-12-22	2005-04-16	H. Lundbeck A/S	Metodo de preparacion de citalopram puro.
DE60100016T2 (de)	2000-12-28	2003-04-17	H. Lundbeck A/S, Valby	Verfahren zur herstellung von reinem citalopram

2000
- 2000-01-21 AR ARP000100271A patent/AR022329A1/es active IP Right Grant
- 2000-01-26 EA EA200100834A patent/EA003257B1/ru not_active IP Right Cessation
- 2000-01-26 WO PCT/DK2000/000032 patent/WO2000044738A1/en active IP Right Grant
- 2000-01-26 DE DE60000364T patent/DE60000364T2/de not_active Expired - Lifetime
- 2000-01-26 SK SK1056-2001A patent/SK284367B6/sk not_active IP Right Cessation
- 2000-01-26 TR TR2001/02135T patent/TR200102135T2/xx unknown
- 2000-01-26 NZ NZ512775A patent/NZ512775A/en not_active IP Right Cessation
- 2000-01-26 SI SI200030024T patent/SI1150966T1/xx unknown
- 2000-01-26 PL PL349908A patent/PL198385B1/pl not_active IP Right Cessation
- 2000-01-26 KR KR10-2001-7008663A patent/KR100430327B1/ko not_active IP Right Cessation
- 2000-01-26 JP JP2000595994A patent/JP2002535397A/ja active Pending
- 2000-01-26 PT PT00901482T patent/PT1150966E/pt unknown
- 2000-01-26 BR BR0008978-8A patent/BR0008978A/pt active Search and Examination
- 2000-01-26 CZ CZ20012734A patent/CZ300257B6/cs not_active IP Right Cessation
- 2000-01-26 EP EP00901482A patent/EP1150966B1/en not_active Expired - Lifetime
- 2000-01-26 AT AT00901482T patent/ATE222900T1/de not_active IP Right Cessation
- 2000-01-26 DK DK00901482T patent/DK1150966T3/da active
- 2000-01-26 ES ES00901482T patent/ES2180508T3/es not_active Expired - Lifetime
- 2000-01-26 AU AU22782/00A patent/AU763666B2/en not_active Ceased
- 2000-01-26 CN CNB008030480A patent/CN1158271C/zh not_active Expired - Fee Related
- 2000-01-26 CA CA002361395A patent/CA2361395C/en not_active Expired - Fee Related
- 2000-01-26 UA UA2001075226A patent/UA70987C2/uk unknown
- 2000-01-26 IL IL14411400A patent/IL144114A0/xx active IP Right Grant
- 2000-01-26 HU HU0104976A patent/HUP0104976A3/hu unknown
- 2000-01-27 IT IT2000MI000112A patent/IT1317741B1/it active
2001
- 2001-06-28 IS IS5982A patent/IS2223B/is unknown
- 2001-07-02 IL IL144114A patent/IL144114A/en not_active IP Right Cessation
- 2001-07-05 ZA ZA200105549A patent/ZA200105549B/en unknown
- 2001-07-10 BG BG105692A patent/BG64924B1/bg unknown
- 2001-07-26 NO NO20013667A patent/NO326532B1/no not_active IP Right Cessation
- 2001-07-27 US US09/917,180 patent/US6441201B1/en not_active Expired - Fee Related
2002
- 2002-08-15 HK HK02105984.5A patent/HK1044342B/zh not_active IP Right Cessation

Also Published As

Publication number	Publication date
EP1150966B1 (en)	2002-08-28
DK1150966T3 (da)	2002-12-30
AU763666B2 (en)	2003-07-31
DE60000364D1 (de)	2002-10-02
UA70987C2 (uk)	2004-11-15
BG64924B1 (bg)	2006-09-29
PT1150966E (pt)	2003-01-31
ITMI20000112A0 (it)	2000-01-27
SK284367B6 (sk)	2005-02-04
NO20013667L (no)	2001-07-26
ITMI20000112A1 (it)	2001-07-27
KR100430327B1 (ko)	2004-05-03
US20020028956A1 (en)	2002-03-07
CA2361395C (en)	2005-11-15
HUP0104976A3 (en)	2002-09-30
ES2180508T3 (es)	2003-02-16
ATE222900T1 (de)	2002-09-15
IL144114A (en)	2006-06-11
NZ512775A (en)	2003-11-28
JP2002535397A (ja)	2002-10-22
CZ20012734A3 (cs)	2002-01-16
IS5982A (is)	2001-06-28
PL198385B1 (pl)	2008-06-30
EP1150966A1 (en)	2001-11-07
PL349908A1 (en)	2002-10-07
CZ300257B6 (cs)	2009-04-01
HK1044342A1 (en)	2002-10-18
HK1044342B (zh)	2005-04-22
IL144114A0 (en)	2002-05-23
CN1337957A (zh)	2002-02-27
HUP0104976A2 (en)	2002-06-29
BG105692A (en)	2002-02-28
EA200100834A1 (ru)	2001-12-24
KR20010101432A (ko)	2001-11-14
DE60000364T2 (de)	2003-04-03
NO326532B1 (no)	2008-12-29
SK10562001A3 (sk)	2002-01-07
ZA200105549B (en)	2002-07-05
IS2223B (is)	2007-03-15
CN1158271C (zh)	2004-07-21
EA003257B1 (ru)	2003-02-27
AR022329A1 (es)	2002-09-04
BR0008978A (pt)	2001-11-27
NO20013667D0 (no)	2001-07-26
SI1150966T1 (en)	2003-02-28
US6441201B1 (en)	2002-08-27
TR200102135T2 (tr)	2002-01-21
WO2000044738A1 (en)	2000-08-03
AU2278200A (en)	2000-08-18
CA2361395A1 (en)	2000-08-03

Publication	Publication Date	Title
IT1317741B1 (it)	2003-07-15	Metodo per la preparazione di 5-cianoftalide.
ITMI991580A0 (it)	1999-07-15	Metodo per la preparazione di citalopram
ITMI991579A0 (it)	1999-07-15	Metodo per la preparazione di citalopram
ITMI991581A0 (it)	1999-07-15	Metodo per la preparazione di citalopram
IT1317757B1 (it)	2003-07-15	Metodo per la preparazione di idrocarburi idrogenati.
CY2007029I1 (el)	2009-11-04	Μεθοδος για την παρασκευη υποκατεστημενων οκτανοϋλ-αμιδιων
IT1315269B1 (it)	2003-02-03	Metodo per la preparazione di 5-cianoftalide
IT1319251B1 (it)	2003-09-26	Metodo per la preparazione di 5-carbossiftalide.
ID28489A (id)	2001-05-31	Metode untuk membuat 4-karboksiamino-2-disubstitusi 1,2,3,4-tetrahidroquinolin
IT1317716B1 (it)	2003-07-15	Processo per la preparazione di perfluoropoliossialchileni conterminali ossidrilici.
ITMI991658A0 (it)	1999-07-27	Procedimento per la preparazione di epossidi
TR199800403A3 (tr)	1998-09-21	a-Bromo-laktam türevlerinin hazirlanmasi için yöntem.
IT1319242B1 (it)	2003-09-26	Processo per la preparazione di maleato di fluvossamina.
IT1313660B1 (it)	2002-09-09	Procedimento stereoselettivo per la preparazione di endo-3-amminoazabicicloalcani.
ITMI981796A0 (it)	1998-07-31	Procedimento per la preparazione di r-(-)-carnitina
TR199900757A3 (tr)	1999-11-22	Fenoksifenilsülfonil halidlerin hazirlanmasi için islem.
ITMI992457A0 (it)	1999-11-25	Procedimento per la preparazione di (s)-n-terbutil-1,2,3,4-tetraidrois ochinolin-3-carbossiammide
IT1304031B1 (it)	2001-03-02	Metodo per la preparazione di glucofanina.
ITMI992505A0 (it)	1999-12-01	Metodo per la preparazione di citlopram
ITMI991329A0 (it)	1999-06-15	Procedimento per la preparazione di tetrafluoroalogenobenzeni
IT1313588B1 (it)	2002-09-09	Processo per la preparazione di trans-4-p-fluorofenil-3-idrossimetil-piperidina.
IT1318371B1 (it)	2003-08-25	Processo per la preparazione di eterocicli.
ITMI20001600A1 (it)	2002-01-15	Procedimento per la preparazione di 5-amino-4-alo-3-alchil isossazoli.
ITTO20000397A0 (it)	2000-04-27	Procedimento perfezionato per la preparazione di 4-alchil-3-alcossianiline.
IT1311985B1 (it)	2002-03-22	Procedimento per la preparazione di isosorbide-5-mononitrato.