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IT1191665B - Analoghi di ammino prostaglandine tiabicicloeptano-sostituite - Google Patents

Analoghi di ammino prostaglandine tiabicicloeptano-sostituite

Info

Publication number
IT1191665B
IT1191665B IT19557/86A IT1955786A IT1191665B IT 1191665 B IT1191665 B IT 1191665B IT 19557/86 A IT19557/86 A IT 19557/86A IT 1955786 A IT1955786 A IT 1955786A IT 1191665 B IT1191665 B IT 1191665B
Authority
IT
Italy
Prior art keywords
tiabicicloeptano
prostaglandine
analogs
amino
replaced
Prior art date
Application number
IT19557/86A
Other languages
English (en)
Other versions
IT8619557A1 (it
IT8619557A0 (it
Inventor
Nakane Masami
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Publication of IT8619557A0 publication Critical patent/IT8619557A0/it
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of IT8619557A1 publication Critical patent/IT8619557A1/it
Application granted granted Critical
Publication of IT1191665B publication Critical patent/IT1191665B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IT19557/86A 1985-02-28 1986-02-28 Analoghi di ammino prostaglandine tiabicicloeptano-sostituite IT1191665B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/706,813 US4588741A (en) 1985-02-28 1985-02-28 Platelet aggregation inhibiting and bronchoconstriction inhibiting thiabicycloheptane substituted amino prostaglandin analog derivatives, compositions, and method of use therefor

Publications (3)

Publication Number Publication Date
IT8619557A0 IT8619557A0 (it) 1986-02-27
IT8619557A1 IT8619557A1 (it) 1987-08-28
IT1191665B true IT1191665B (it) 1988-03-23

Family

ID=24839157

Family Applications (1)

Application Number Title Priority Date Filing Date
IT19557/86A IT1191665B (it) 1985-02-28 1986-02-28 Analoghi di ammino prostaglandine tiabicicloeptano-sostituite

Country Status (7)

Country Link
US (1) US4588741A (it)
JP (1) JPS61210082A (it)
CA (1) CA1267150C (it)
DE (1) DE3606431A1 (it)
FR (1) FR2577928B1 (it)
GB (1) GB2171699B (it)
IT (1) IT1191665B (it)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4735962A (en) * 1986-10-06 1988-04-05 E. R. Squibb & Sons, Inc. 7-thiabicycloheptane substituted diamide and its congener prostaglandin analogs
CA2450073C (en) 2001-07-25 2017-08-29 Biomarin Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
EP2392258B1 (en) 2005-04-28 2014-10-08 Proteus Digital Health, Inc. Pharma-informatics system
MX2009002893A (es) 2006-09-18 2009-07-10 Raptor Pharmaceutical Inc Tratamiento de trastornos hepaticos mediante la administracion de conjugados de la proteina asociada al receptor (rap).
ES2919563T3 (es) 2009-02-20 2022-07-27 Enhanx Biopharm Inc Sistema de administración de medicamentos a base de glutatión
EP2427178B1 (en) 2009-05-06 2023-01-04 Laboratory Skin Care, Inc. Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4220594A (en) * 1977-11-04 1980-09-02 E. R. Squibb & Sons, Inc. Hexa- and octahydro-4,7-epoxyisobenzofuran-1-ol and hexa- and octahydro-5,8-epoxy-1H-2-benzopyran-3-ol
US4143054A (en) * 1977-11-04 1979-03-06 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane- and 7-oxabicycloheptene compounds
US4187236A (en) * 1977-11-04 1980-02-05 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane compounds
US4254044A (en) * 1977-11-04 1981-03-03 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane- and 7-oxabicycloheptene compounds
EP0013607B1 (en) * 1979-01-05 1983-03-23 National Research Development Corporation Substituted bicyclo (2,2,1)heptanes and bicyclo (2,2,1) hept-2-enes and their pharmaceutical compositions
US4228180A (en) * 1979-11-01 1980-10-14 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane and 7-oxabicycloheptene prostaglandin analogs
ZA814307B (en) * 1980-07-01 1983-02-23 Nat Res Dev Prostaglandins
US4416896A (en) * 1982-05-17 1983-11-22 E. R. Squibb & Sons, Inc. 7-Oxabicyclopheptane substituted amino prostaglandin analogs useful in the treatment of thrombolytic disease
US4456615A (en) * 1982-10-25 1984-06-26 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane substituted amino prostaglandin analogs and their use in inhibiting platelet aggregation and bronchoconstriction
US4456617A (en) * 1983-01-12 1984-06-26 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane substituted amino prostaglandin analogs and their use in inhibiting platelet aggregation and bronchoconstriction
US4466979A (en) * 1983-01-21 1984-08-21 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane substituted carbamate prostaglandin analogs useful in treating platelet aggregation and bronchoconstriction
US4526901A (en) * 1984-01-26 1985-07-02 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane substituted oxamide prostaglandin analogs and their use in treating thrombolytic disease

Also Published As

Publication number Publication date
US4588741A (en) 1986-05-13
IT8619557A1 (it) 1987-08-28
GB2171699A (en) 1986-09-03
GB8603629D0 (en) 1986-03-19
CA1267150A (en) 1990-03-27
CA1267150C (en) 1990-03-27
FR2577928A1 (fr) 1986-08-29
FR2577928B1 (fr) 1988-08-26
IT8619557A0 (it) 1986-02-27
JPS61210082A (ja) 1986-09-18
DE3606431A1 (de) 1986-08-28
GB2171699B (en) 1988-07-13

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