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IT1150022B - 1,9-diidrossioctaidrobenzo (c) chinoline e 1-idrossiesaidrobenzo (c) chinolin-9(8h)-oni come agenti antiemetici - Google Patents

1,9-diidrossioctaidrobenzo (c) chinoline e 1-idrossiesaidrobenzo (c) chinolin-9(8h)-oni come agenti antiemetici

Info

Publication number
IT1150022B
IT1150022B IT23058/80A IT2305880A IT1150022B IT 1150022 B IT1150022 B IT 1150022B IT 23058/80 A IT23058/80 A IT 23058/80A IT 2305880 A IT2305880 A IT 2305880A IT 1150022 B IT1150022 B IT 1150022B
Authority
IT
Italy
Prior art keywords
hydroxiesa
dihydroxioctahydrobenzo
hydrobenzo
quinolin
quinoline
Prior art date
Application number
IT23058/80A
Other languages
English (en)
Other versions
IT8023058A0 (it
Inventor
Michael Ross Johnson
Milne George Mclean
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of IT8023058A0 publication Critical patent/IT8023058A0/it
Application granted granted Critical
Publication of IT1150022B publication Critical patent/IT1150022B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/06—Ring systems of three rings
    • C07D221/10—Aza-phenanthrenes
    • C07D221/12—Phenanthridines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
IT23058/80A 1979-06-26 1980-06-26 1,9-diidrossioctaidrobenzo (c) chinoline e 1-idrossiesaidrobenzo (c) chinolin-9(8h)-oni come agenti antiemetici IT1150022B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/052,324 US4228169A (en) 1979-06-26 1979-06-26 1,9-Dihydroxyoctahydrobenzo[c]quinolines and 1-hydroxyhexahydrobenzo[c]quinoline-9(8H)-ones as antiemetic agents

Publications (2)

Publication Number Publication Date
IT8023058A0 IT8023058A0 (it) 1980-06-26
IT1150022B true IT1150022B (it) 1986-12-10

Family

ID=21976860

Family Applications (1)

Application Number Title Priority Date Filing Date
IT23058/80A IT1150022B (it) 1979-06-26 1980-06-26 1,9-diidrossioctaidrobenzo (c) chinoline e 1-idrossiesaidrobenzo (c) chinolin-9(8h)-oni come agenti antiemetici

Country Status (7)

Country Link
US (1) US4228169A (it)
JP (1) JPS567718A (it)
BE (1) BE883995A (it)
DE (1) DE3023626A1 (it)
IT (1) IT1150022B (it)
PH (1) PH14827A (it)
ZA (1) ZA803781B (it)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4340737A (en) * 1979-05-29 1982-07-20 Pfizer Inc. 9-Hydroxyoctahydrobenzo[C]quinolines and intermediates therefor
US4400385A (en) * 1980-10-03 1983-08-23 Pfizer Inc. 9-Hydroxyoctahydrobenzo [c]quinolines, analgesic compositions containing them and processes for producing analgesia with them
US4405626A (en) * 1980-10-03 1983-09-20 Pfizer Inc. 9-Hydroxyoctahydrobenzo(c)quinolines analgesic compositions containing them and processes for producing analgesic with them
US4320124A (en) * 1980-10-17 1982-03-16 Pfizer Inc. Composition for enhancing binding of a benzodiazepine to central benzodiazepine receptors and use thereof
US4920221A (en) * 1982-03-16 1990-04-24 Pfizer Inc. Substituted decahydro-1H-pyrido[1,2-f]phenanthridines and decahydropyrrolo[1,2-f]phenanthridines
US4870084A (en) * 1982-03-16 1989-09-26 Pfizer Inc. Bicyclic benzo fused pyran compounds used for nausea treatment and prevention
US4473704A (en) * 1982-03-16 1984-09-25 Pfizer Inc. Substituted dodecahydrotriphenylenes, decahydro-1H-cyclopenta[1]phenanthrenes, decahydro-1H-pyrido[1,2-f]phenanthridines and decahydropyrrolo[1,2-f]phenanthridines as CNS agents
US4841078A (en) * 1982-03-16 1989-06-20 Pfizer Inc. Benzopyrans
US4642373A (en) * 1982-03-16 1987-02-10 Pfizer Inc. Substituted dodecahydrotripheylenes, and decahydropyrrolo[1,2-f]phenanthridines as CNS agents
US4863934A (en) * 1982-03-16 1989-09-05 Pfizer Inc. Bicyclic benzo fused pyran compounds used for producing analgesia
US4486428A (en) * 1982-03-16 1984-12-04 Pfizer Inc. Bicyclic benzo fused compounds
US4680404A (en) * 1983-01-13 1987-07-14 Pfizer Inc. Benzopyrans
US4943428A (en) * 1987-07-10 1990-07-24 Wright State University Stimulation of serotonin-1A receptors in mammals to alleviate motion sickness and emesis induced by chemical agents
US5863928A (en) 1993-11-19 1999-01-26 The Board Of Governors For Higher Education The State Of Rhode Island And Providence Plantation. Octahydrobenzo f!quinoline-based receptor agonists and antagonists
US5605906A (en) * 1995-03-24 1997-02-25 Merck Frosst Canada, Inc. Cannabinoid receptor agonists
AU2005247480A1 (en) * 2004-05-25 2005-12-08 Qlt Inc. Oculoselective drugs and prodrugs
AU2005282829A1 (en) * 2004-09-02 2006-03-16 Wyeth Phenanthridine carbonyl phenols as cytokine modulators
JP2023500372A (ja) 2019-11-08 2023-01-05 ヴェラ・バイオサイエンス・インコーポレイテッド 女性の性機能を強化するかまたは女性の性障害を治療するための末梢作用性カンナビジオール（ｃｂｄ）含有組成物およびその使用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4087545A (en) * 1976-02-17 1978-05-02 Eli Lilly And Company Hexahydro-dibenzo[b,d]pyran-9-ones as antiemetic drugs
SE7704749L (sv) * 1976-05-17 1977-12-05 Pfizer Kinoliner och forfarande och mellanprodukter for framstellning derav
ZA772899B (en) 1976-05-17 1978-04-26 Pfizer 9-hydroxyhexahydrobenzol(c)quinolines and intermediates therefor

Also Published As

Publication number Publication date
JPS567718A (en) 1981-01-27
PH14827A (en) 1981-12-16
ZA803781B (en) 1981-06-24
DE3023626C2 (it) 1988-02-04
DE3023626A1 (de) 1981-01-08
IT8023058A0 (it) 1980-06-26
US4228169A (en) 1980-10-14
BE883995A (fr) 1980-12-29

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