IT1147763B - Composti utilizzabili come agenti inibitori della biosintesi del colesterolo e procedimento per la loro preparazione - Google Patents
Composti utilizzabili come agenti inibitori della biosintesi del colesterolo e procedimento per la loro preparazioneInfo
- Publication number
- IT1147763B IT1147763B IT68211/80A IT6821180A IT1147763B IT 1147763 B IT1147763 B IT 1147763B IT 68211/80 A IT68211/80 A IT 68211/80A IT 6821180 A IT6821180 A IT 6821180A IT 1147763 B IT1147763 B IT 1147763B
- Authority
- IT
- Italy
- Prior art keywords
- compounds
- procedure
- preparation
- biosynthesis inhibitors
- cholesterol biosynthesis
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
- C07C59/46—Unsaturated compounds containing hydroxy or O-metal groups containing rings other than six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/732—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids of unsaturated hydroxy carboxylic acids
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E50/00—Technologies for the production of fuel of non-fossil origin
- Y02E50/10—Biofuels, e.g. bio-diesel
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP9581479A JPS5621594A (en) | 1979-07-27 | 1979-07-27 | Mb-530b carboxylic acid metal salt and its preparation |
| JP12346179A JPS5646841A (en) | 1979-09-26 | 1979-09-26 | Mb-530b carboxylic acid ester and its preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT8068211A0 IT8068211A0 (it) | 1980-07-28 |
| IT1147763B true IT1147763B (it) | 1986-11-26 |
Family
ID=26436995
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT68211/80A IT1147763B (it) | 1979-07-27 | 1980-07-28 | Composti utilizzabili come agenti inibitori della biosintesi del colesterolo e procedimento per la loro preparazione |
Country Status (16)
| Country | Link |
|---|---|
| AT (1) | AT375334B (es) |
| AU (1) | AU6083980A (es) |
| CH (1) | CH647749A5 (es) |
| DD (1) | DD153827A5 (es) |
| DE (1) | DE3028284A1 (es) |
| DK (1) | DK322380A (es) |
| ES (1) | ES8105781A1 (es) |
| FI (1) | FI71300C (es) |
| FR (1) | FR2462417A1 (es) |
| GB (1) | GB2055100A (es) |
| IT (1) | IT1147763B (es) |
| NL (1) | NL8004303A (es) |
| NO (1) | NO156210C (es) |
| NZ (1) | NZ194445A (es) |
| PL (1) | PL225901A1 (es) |
| SE (1) | SE445828B (es) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1327360C (en) * | 1983-11-14 | 1994-03-01 | William F. Hoffman | Oxo-analogs of mevinolin-like antihypercholesterolemic agents |
| EP0164049B1 (en) * | 1984-06-04 | 1990-12-12 | Merck & Co. Inc. | Process for preparing hmg-coa reductase inhibtors with a 3,5-dihydroxypentanoate subunit |
| EP0204287A3 (en) * | 1985-06-04 | 1987-07-01 | Merck & Co. Inc. | Process for the preparation of hmg-coa reductase inhibitors with a 3,5-dihydroxypentanoate subunit |
| US4611081A (en) * | 1985-07-05 | 1986-09-09 | Merck & Co., Inc. | Process for the preparation of HMG-CoA reductase inhibitors intermediates |
| USRE33033E (en) * | 1985-07-05 | 1989-08-22 | Merck & Co., Inc. | Process for the preparation of HMG-CoA reductase inhibitors intermediates |
| US7238348B2 (en) | 1996-09-30 | 2007-07-03 | Beijing Peking University Wbl Corporation Ltd. | Method of treatment of osteoporosis with compositions of red rice fermentation products |
| US6046022A (en) | 1996-09-30 | 2000-04-04 | Peking University | Methods and compositions employing red rice fermentation products |
| JP2002518448A (ja) * | 1998-06-24 | 2002-06-25 | メルク エンド カムパニー インコーポレーテッド | 高血中コレステロールを治療する組成物および方法 |
| SI20070A (sl) | 1998-09-18 | 2000-04-30 | LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. | Nove soli inhibitorjev HMG-CoA reduktaze |
| US6806290B2 (en) | 2000-06-09 | 2004-10-19 | Lek Pharmaceuticals D.D. | Stabilized pharmaceutically effective composition and pharmaceutical formulation comprising the same |
| US6531507B1 (en) * | 2000-06-09 | 2003-03-11 | Lek Pharmaceuticals D.D. | Stabilized pharmaceutically effective composition and pharmaceutical formulation comprising the same |
| AU2001288724A1 (en) * | 2000-09-06 | 2002-03-22 | Merck & Co., Inc. | Dihydroxy open-acid salt of simvastatin |
| CZ200450A3 (cs) | 2001-06-13 | 2004-05-12 | Ranbaxyálaboratoriesálimited | Methylové analogy simvastatinu jako například nové inhibitory HMG@CoA reduktázy |
| KR100379075B1 (en) | 2002-03-07 | 2003-04-08 | Jinis Biopharmaceuticals Co | Method for producing low cholesterol animal food product and food product therefrom |
| US8158362B2 (en) | 2005-03-30 | 2012-04-17 | Decode Genetics Ehf. | Methods of diagnosing susceptibility to myocardial infarction and screening for an LTA4H haplotype |
| CN101659923B (zh) * | 2008-08-26 | 2011-10-26 | 北京北大维信生物科技有限公司 | 一种制备开环式洛伐他汀的方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4137322A (en) * | 1976-11-02 | 1979-01-30 | Sankyo Company Limited | ML-236B carboxylic acid derivatives and their use as antihyperlipemic agents |
| JPS55150898A (en) * | 1979-05-11 | 1980-11-25 | Sankyo Co Ltd | Preparation of a new physiologically active substance mb-530b |
-
1980
- 1980-07-24 ES ES493726A patent/ES8105781A1/es not_active Expired
- 1980-07-25 CH CH5736/80A patent/CH647749A5/de not_active IP Right Cessation
- 1980-07-25 DE DE19803028284 patent/DE3028284A1/de active Granted
- 1980-07-25 FR FR8016452A patent/FR2462417A1/fr active Granted
- 1980-07-25 NZ NZ194445A patent/NZ194445A/en unknown
- 1980-07-25 NO NO802244A patent/NO156210C/no unknown
- 1980-07-25 FI FI802357A patent/FI71300C/fi not_active IP Right Cessation
- 1980-07-25 DK DK322380A patent/DK322380A/da not_active Application Discontinuation
- 1980-07-25 SE SE8005386A patent/SE445828B/sv not_active IP Right Cessation
- 1980-07-26 PL PL22590180A patent/PL225901A1/xx unknown
- 1980-07-27 NL NL8004303A patent/NL8004303A/nl not_active Application Discontinuation
- 1980-07-28 IT IT68211/80A patent/IT1147763B/it active
- 1980-07-28 AT AT0392380A patent/AT375334B/de not_active IP Right Cessation
- 1980-07-28 GB GB8024665A patent/GB2055100A/en not_active Withdrawn
- 1980-07-28 DD DD80222916A patent/DD153827A5/de unknown
- 1980-07-28 AU AU60839/80A patent/AU6083980A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CH647749A5 (de) | 1985-02-15 |
| ATA392380A (de) | 1983-12-15 |
| DD153827A5 (de) | 1982-02-03 |
| IT8068211A0 (it) | 1980-07-28 |
| NO156210C (no) | 1987-08-12 |
| SE445828B (sv) | 1986-07-21 |
| FR2462417B1 (es) | 1984-01-20 |
| DK322380A (da) | 1981-01-28 |
| NO802244L (no) | 1981-01-28 |
| SE8005386L (sv) | 1981-01-28 |
| AU6083980A (en) | 1981-01-29 |
| FI802357A (fi) | 1981-01-28 |
| PL225901A1 (es) | 1982-07-19 |
| NO156210B (no) | 1987-05-04 |
| AT375334B (de) | 1984-07-25 |
| ES493726A0 (es) | 1981-06-16 |
| GB2055100A (en) | 1981-02-25 |
| ES8105781A1 (es) | 1981-06-16 |
| NZ194445A (en) | 1984-07-06 |
| DE3028284C2 (es) | 1990-08-09 |
| DE3028284A1 (de) | 1981-02-19 |
| NL8004303A (nl) | 1981-01-29 |
| FI71300C (fi) | 1986-12-19 |
| FI71300B (fi) | 1986-09-09 |
| FR2462417A1 (fr) | 1981-02-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19970730 |