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IT1101735B - Agenti anticolinergici labili aventi attivita' antisecretoria - Google Patents

Agenti anticolinergici labili aventi attivita' antisecretoria

Info

Publication number
IT1101735B
IT1101735B IT30735/78A IT3073578A IT1101735B IT 1101735 B IT1101735 B IT 1101735B IT 30735/78 A IT30735/78 A IT 30735/78A IT 3073578 A IT3073578 A IT 3073578A IT 1101735 B IT1101735 B IT 1101735B
Authority
IT
Italy
Prior art keywords
labili
secretory activity
anticolinergic agents
anticolinergic
agents
Prior art date
Application number
IT30735/78A
Other languages
English (en)
Other versions
IT7830735A0 (it
Inventor
Nicholas Stephen Bodor
Original Assignee
Recordati Chem Pharm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Recordati Chem Pharm filed Critical Recordati Chem Pharm
Publication of IT7830735A0 publication Critical patent/IT7830735A0/it
Application granted granted Critical
Publication of IT1101735B publication Critical patent/IT1101735B/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79Acids; Esters
    • C07D213/80Acids; Esters in position 3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00Thiocarboxylic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87Benzo [c] furans; Hydrogenated benzo [c] furans
    • C07D307/90Benzo [c] furans; Hydrogenated benzo [c] furans with an oxygen atom in position 1 and a nitrogen atom in position 3, or vice versa
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D453/00Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
IT30735/78A 1977-12-16 1978-12-12 Agenti anticolinergici labili aventi attivita' antisecretoria IT1101735B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US86121077A 1977-12-16 1977-12-16

Publications (2)

Publication Number Publication Date
IT7830735A0 IT7830735A0 (it) 1978-12-12
IT1101735B true IT1101735B (it) 1985-10-07

Family

ID=25335183

Family Applications (1)

Application Number Title Priority Date Filing Date
IT30735/78A IT1101735B (it) 1977-12-16 1978-12-12 Agenti anticolinergici labili aventi attivita' antisecretoria

Country Status (15)

Country Link
JP (1) JPS5498711A (it)
AR (1) AR222478A1 (it)
AT (1) AT366380B (it)
AU (1) AU531835B2 (it)
CA (1) CA1102345A (it)
DE (1) DE2854308A1 (it)
DK (1) DK534178A (it)
ES (1) ES476048A1 (it)
FR (1) FR2422624A1 (it)
GB (1) GB2010270B (it)
IE (1) IE48012B1 (it)
IT (1) IT1101735B (it)
NL (1) NL7812257A (it)
NO (1) NO148776C (it)
SE (1) SE436027B (it)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3045055A1 (de) * 1980-11-29 1982-07-01 Celamerck Gmbh & Co Kg, 6507 Ingelheim Heterocyclische verbindungen
JPS5993075A (ja) * 1982-11-18 1984-05-29 Shionogi & Co Ltd 1−フタリジル−5−フルオロウラシル誘導体の製造法
US5008111A (en) * 1984-10-11 1991-04-16 Schering Corporation Physiological means of enhancing transdermal delivery of drugs
US4824676A (en) * 1984-10-11 1989-04-25 Schering Corporation Physiological means of enhancing transdermal delivery of drugs
FR2703046B1 (fr) * 1993-03-26 1995-05-05 Poudres & Explosifs Ste Nale Procédé de préparation d'oxalates et d'halogénoglyoxalates alpha- monohalogénés et nouveaux oxalates et halogénoglyoxalates alpha-monohalogénés .
AUPN814496A0 (en) 1996-02-19 1996-03-14 Monash University Dermal penetration enhancer
US5962505A (en) * 1998-08-31 1999-10-05 Bobrove; Arthur M. Method for treating hot flashes in humans
US6433003B1 (en) 1999-04-23 2002-08-13 Arthur M. Bobrove Method for treating hyperhidrosis in mammals
AR044134A1 (es) * 2003-05-02 2005-08-24 Novartis Ag Derivados de quinuclidina, metodo de preparacion y composiciones farmaceuticas.
EA019214B1 (ru) 2005-06-03 2014-02-28 АКРУКС ДиДиЭс ПиТиУай ЭлТиДи Способ лечения или профилактики заболеваний, вызванных дефицитом андрогенов у взрослых мужчин
US20100222393A1 (en) * 2005-12-30 2010-09-02 Naresh Kumar Muscarinic receptor antagonists
PT2214643E (pt) 2007-11-02 2014-05-26 Acrux Dds Pty Ltd Sistema de entrega transdérmica para hormonas e esteroides
JP6621329B2 (ja) * 2012-10-05 2019-12-18 スファエラ ファーマ ピーティーイー リミテッド 新規化合物、それらの合成及びそれらの使用
DE102013013397A1 (de) 2013-08-13 2015-03-12 Epinamics Gmbh Aerosolspender für transdermal wirkende pharmazeutische Zusammensetzungen
CN110041264A (zh) * 2019-04-11 2019-07-23 贺州学院 一种金刚烷基咪唑类离子液体及其制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL101555C (it) * 1955-03-19
BE798253A (nl) * 1973-04-16 1973-10-16 Bekaert Sa Nv Zitmeubel
US3998815A (en) * 1974-06-24 1976-12-21 Interx Research Corporation 1-hydrocarbonoyloxymethyl-3-carbamoyl or 3-carboethoxy-pyridinium salts

Also Published As

Publication number Publication date
SE436027B (sv) 1984-11-05
NO148776B (no) 1983-09-05
JPS5498711A (en) 1979-08-03
AU4264678A (en) 1979-06-21
ES476048A1 (es) 1979-11-01
DE2854308A1 (de) 1979-06-21
FR2422624B1 (it) 1983-10-14
AT366380B (de) 1982-04-13
AU531835B2 (en) 1983-09-08
FR2422624A1 (fr) 1979-11-09
CA1102345A (en) 1981-06-02
IE48012B1 (en) 1984-09-05
NO148776C (no) 1983-12-14
ATA901478A (de) 1981-08-15
SE7812911L (sv) 1979-06-17
NL7812257A (nl) 1979-06-19
NO784229L (no) 1979-06-19
DK534178A (da) 1979-06-17
IT7830735A0 (it) 1978-12-12
GB2010270A (en) 1979-06-27
GB2010270B (en) 1982-10-20
IE782499L (en) 1979-06-16
AR222478A1 (es) 1981-05-29

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