IS7874A - Ímídasókínólínafleiður sem adenósín A3 viðtakabindlar - Google Patents

Ímídasókínólínafleiður sem adenósín A3 viðtakabindlar

Info

Publication number: IS7874A
Authority: IS; Iceland
Prior art keywords: adenosine; receptors; imidazoquinoline derivatives; imidazoquinoline; derivatives
Prior art date: 2002-11-15

Application number

IS7874A

Other languages

English (en)

Other versions

IS2456B (is

Inventor

Ar βnyi Peter

βszlo Bal βzs L

βria Balogh M

βndor B βtori S

T. Nagy Lajos

Tím βri Géza

Boér Kinga

βn Kapui Zolt

Mikus Endre

Gerber Katalin

Varg βné Szeredi Judit

Urb βn-Szabo Katalin

Walcz Erzsébet

Original Assignee

Sanofi-Aventis

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-11-15

Filing date

2005-05-31

Publication date

2005-05-31

2005-05-31 Application filed by Sanofi-Aventis filed Critical Sanofi-Aventis

2005-05-31 Publication of IS7874A publication Critical patent/IS7874A/is

2008-11-15 Publication of IS2456B publication Critical patent/IS2456B/is

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P11/02—Nasal agents, e.g. decongestants
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
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- A61P17/04—Antipruritics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pulmonology (AREA)
Diabetes (AREA)
Cardiology (AREA)
Psychiatry (AREA)
Urology & Nephrology (AREA)
Dermatology (AREA)
Immunology (AREA)
Heart & Thoracic Surgery (AREA)
Hematology (AREA)
Rheumatology (AREA)
Obesity (AREA)
Psychology (AREA)
Ophthalmology & Optometry (AREA)
Pain & Pain Management (AREA)
Epidemiology (AREA)
Emergency Medicine (AREA)
Hospice & Palliative Care (AREA)
Vascular Medicine (AREA)
Endocrinology (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Otolaryngology (AREA)

IS7874A 2002-11-15 2005-05-31 Ímídasókínólínafleiður sem adenósín A3 viðtakabindlar IS2456B (is)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
HU0203976A HUP0203976A3 (en)	2002-11-15	2002-11-15	Adenozine a3 receptors, process for their preparation and pharmaceutical compositions containing them
PCT/HU2003/000095 WO2004046146A1 (en)	2002-11-15	2003-11-11	Imidazoquinoline derivatives as adenosine a3 receptor ligands

Publications (2)

Publication Number	Publication Date
IS7874A true IS7874A (is)	2005-05-31
IS2456B IS2456B (is)	2008-11-15

Family

ID=90001561

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IS7874A IS2456B (is)	2002-11-15	2005-05-31	Ímídasókínólínafleiður sem adenósín A3 viðtakabindlar

Country Status (35)

Country	Link
US (2)	US7419977B2 (is)
EP (1)	EP1560828B9 (is)
JP (1)	JP4533148B2 (is)
KR (1)	KR20050088291A (is)
CN (1)	CN1332960C (is)
AR (1)	AR041968A1 (is)
AT (1)	ATE325123T1 (is)
AU (1)	AU2003282263B2 (is)
BR (1)	BR0316355A (is)
CA (1)	CA2505910C (is)
CO (1)	CO5690577A2 (is)
CY (1)	CY1105180T1 (is)
DE (1)	DE60305058T2 (is)
DK (1)	DK1560828T3 (is)
EA (1)	EA007595B1 (is)
ES (1)	ES2263039T3 (is)
HK (1)	HK1077819A1 (is)
HR (1)	HRP20050540A2 (is)
HU (1)	HUP0203976A3 (is)
IL (1)	IL168516A (is)
IS (1)	IS2456B (is)
MA (1)	MA27501A1 (is)
ME (1)	MEP19008A (is)
MX (1)	MXPA05005198A (is)
NO (1)	NO20052866L (is)
NZ (1)	NZ540029A (is)
PL (1)	PL376837A1 (is)
PT (1)	PT1560828E (is)
RS (1)	RS51320B (is)
SI (1)	SI1560828T1 (is)
TN (1)	TNSN05133A1 (is)
TW (1)	TWI248934B (is)
UA (1)	UA78889C2 (is)
WO (1)	WO2004046146A1 (is)
ZA (1)	ZA200503807B (is)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HUP0105406A3 (en) *	2001-12-21	2003-12-29	Sanofi Aventis	Imidazo[1,2-a]quinolin derivatives, process for their preparation, pharmaceutical compositions thereof and intermediates
HUP0203976A3 (en) *	2002-11-15	2004-08-30	Sanofi Aventis	Adenozine a3 receptors, process for their preparation and pharmaceutical compositions containing them
HUP0400812A2 (en) *	2004-04-19	2006-02-28	Sanofi Aventis	Crystalline forms of 2-amino-3-cyano-quinoline derivatives, process for their preparation and pharmaceutical compositions containing them
GT200600381A (es)	2005-08-25	2007-03-28		Compuestos organicos
US20090088403A1 (en) *	2007-05-07	2009-04-02	Randy Blakely	A3 adenosine receptors as targets for the modulation of central serotonergic signaling
HUP0700395A2 (en) *	2007-06-07	2009-03-02	Sanofi Aventis	Substituted [1,2,4] triazolo [1,5-a] quinolines, process for their preparation, pharmaceutical compositions thereof, and intermediates
WO2011010306A1 (en)	2009-07-21	2011-01-27	Ramot At Tel-Aviv University Ltd.	A3 adenosine receptor ligands for modulation of pigmentation
MX369611B (es)	2013-02-01	2019-11-14	Wellstat Therapeutics Corp	Compuestos de amina que tienen actividad anti-inflamatoria, antifungica, antiparasitaria y anticancer.
KR101820909B1 (ko) *	2017-07-07	2018-01-23	퓨쳐메디신 주식회사	아데노신 유도체를 포함하는 만성신장질환 예방 및 치료용 약학적 조성물
TWI795440B (zh)	2017-09-15	2023-03-11	美商佛瑪治療公司	作為ＣＢＰ／ｐ３００抑制劑之四氫─咪唑並喹啉化合物
CN112513038B (zh)	2018-06-29	2023-01-10	福马疗法公司	抑制creb结合蛋白(cbp)
BR112021016921A2 (pt) *	2019-03-15	2021-11-03	Forma Therapeutics Inc	Inibição de proteína de ligação a elemento responsivo a amp cíclico (creb)
US11795168B2 (en)	2020-09-23	2023-10-24	Forma Therapeutics, Inc.	Inhibiting cyclic amp-responsive element-binding protein (CREB) binding protein (CBP)
US11801243B2 (en)	2020-09-23	2023-10-31	Forma Therapeutics, Inc.	Bromodomain inhibitors for androgen receptor-driven cancers

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4075343A (en) *	1976-09-13	1978-02-21	Pfizer Inc.	Anti-allergenic 5-alkoxyimidazo[1,2-A]quinoline-2-carboxylic acids and derivatives thereof
GB1596652A (en) *	1977-01-20	1981-08-26	Roussel Lab Ltd	Imidazo (1,2-a) quinoline-2-carboxylic acid and derivatives
IL59104A (en)	1979-02-09	1984-02-29	Roussel Uclaf	Heterotricyclic derivatives,process for their preparation and pharmaceutical compositions incorporating them
FR2448541A1 (fr)	1979-02-09	1980-09-05	Roussel Uclaf	Nouveaux derives de l'oxoimidazoquinoxaline et leurs sels, leur procede de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant
US4644002A (en)	1979-02-09	1987-02-17	Roussel Uclaf	Imidazo[2,1-C]quinolines, useful as antiallergic agents
AU4980999A (en)	1998-07-10	2000-02-01	United States Of America, Represented By The Secretary, Department Of Health And Human Services, The	A3 adenosine receptor antagonists
US6448253B1 (en) *	1998-09-16	2002-09-10	King Pharmaceuticals Research And Development, Inc.	Adenosine A3 receptor modulators
DE60010311T2 (de) *	1999-09-28	2005-05-12	Otsuka Pharmaceutical Factory, Inc., Naruto	Triazolpurin-derivate, medikamentzusammensetzungen, die diese enthalten und mittel, die affinität zum adenosin a3 rezeptor zeigen
US7160890B2 (en) *	1999-12-02	2007-01-09	Osi Pharmaceuticals, Inc.	Compounds specific to adenosine A3 receptor and uses thereof
NZ525885A (en) *	2000-12-01	2005-01-28	Osi Pharm Inc	Compounds specific to adenosine A1, A2A, and A3 receptor and uses as ubiquitous modulators of physiological activities
PL366516A1 (en) *	2001-05-31	2005-02-07	Sanofi-Synthelabo	Aminoquinoline and aminopyridine derivatives and their use as adenosine a3 ligands
HUP0105406A3 (en) *	2001-12-21	2003-12-29	Sanofi Aventis	Imidazo[1,2-a]quinolin derivatives, process for their preparation, pharmaceutical compositions thereof and intermediates
HUP0105407A3 (en) *	2001-12-21	2004-04-28	Sanofi Aventis	Triazolo[1,5-a]quinolin derivatives, process for their preparation, pharmaceutical compositions thereof and intermediates
HUP0203976A3 (en)	2002-11-15	2004-08-30	Sanofi Aventis	Adenozine a3 receptors, process for their preparation and pharmaceutical compositions containing them

2002
- 2002-11-15 HU HU0203976A patent/HUP0203976A3/hu unknown
2003
- 2003-11-11 UA UAA200505875A patent/UA78889C2/uk unknown
- 2003-11-11 AT AT03773882T patent/ATE325123T1/de active
- 2003-11-11 RS YUP-2005/0364A patent/RS51320B/sr unknown
- 2003-11-11 ME MEP-190/08A patent/MEP19008A/xx unknown
- 2003-11-11 ES ES03773882T patent/ES2263039T3/es not_active Expired - Lifetime
- 2003-11-11 DE DE60305058T patent/DE60305058T2/de not_active Expired - Lifetime
- 2003-11-11 EP EP03773882A patent/EP1560828B9/en not_active Expired - Lifetime
- 2003-11-11 EA EA200500830A patent/EA007595B1/ru unknown
- 2003-11-11 WO PCT/HU2003/000095 patent/WO2004046146A1/en active IP Right Grant
- 2003-11-11 BR BR0316355-5A patent/BR0316355A/pt not_active IP Right Cessation
- 2003-11-11 DK DK03773882T patent/DK1560828T3/da active
- 2003-11-11 KR KR1020057008683A patent/KR20050088291A/ko active IP Right Grant
- 2003-11-11 JP JP2004552920A patent/JP4533148B2/ja not_active Expired - Fee Related
- 2003-11-11 SI SI200330299T patent/SI1560828T1/sl unknown
- 2003-11-11 PL PL376837A patent/PL376837A1/pl not_active Application Discontinuation
- 2003-11-11 CA CA2505910A patent/CA2505910C/en not_active Expired - Fee Related
- 2003-11-11 CN CNB2003801062293A patent/CN1332960C/zh not_active Expired - Fee Related
- 2003-11-11 AU AU2003282263A patent/AU2003282263B2/en not_active Ceased
- 2003-11-11 NZ NZ540029A patent/NZ540029A/en not_active IP Right Cessation
- 2003-11-11 MX MXPA05005198A patent/MXPA05005198A/es active IP Right Grant
- 2003-11-11 PT PT03773882T patent/PT1560828E/pt unknown
- 2003-11-14 TW TW092131901A patent/TWI248934B/zh not_active IP Right Cessation
- 2003-11-14 AR ARP030104200A patent/AR041968A1/es unknown
2005
- 2005-05-10 IL IL168516A patent/IL168516A/en not_active IP Right Cessation
- 2005-05-10 TN TNP2005000133A patent/TNSN05133A1/en unknown
- 2005-05-11 ZA ZA200503807A patent/ZA200503807B/en unknown
- 2005-05-16 US US11/130,429 patent/US7419977B2/en not_active Expired - Fee Related
- 2005-05-31 IS IS7874A patent/IS2456B/is unknown
- 2005-06-13 NO NO20052866A patent/NO20052866L/no not_active Application Discontinuation
- 2005-06-13 MA MA28334A patent/MA27501A1/fr unknown
- 2005-06-14 HR HR20050540A patent/HRP20050540A2/xx not_active Application Discontinuation
- 2005-06-14 CO CO05057645A patent/CO5690577A2/es not_active Application Discontinuation
- 2005-11-07 HK HK05109885A patent/HK1077819A1/xx not_active IP Right Cessation
2006
- 2006-07-28 CY CY20061101054T patent/CY1105180T1/el unknown
2008
- 2008-06-17 US US12/140,512 patent/US7709489B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
CO5690577A2 (es)	2006-10-31
IS2456B (is)	2008-11-15
EP1560828B9 (en)	2007-02-14
US20080255110A1 (en)	2008-10-16
ES2263039T3 (es)	2006-12-01
CN1332960C (zh)	2007-08-22
HUP0203976A3 (en)	2004-08-30
HRP20050540A2 (en)	2005-08-31
CY1105180T1 (el)	2010-03-03
US7709489B2 (en)	2010-05-04
AR041968A1 (es)	2005-06-01
WO2004046146A1 (en)	2004-06-03
RS51320B (sr)	2010-12-31
ATE325123T1 (de)	2006-06-15
DK1560828T3 (da)	2006-09-04
HUP0203976A2 (hu)	2004-07-28
UA78889C2 (en)	2007-04-25
PL376837A1 (pl)	2006-01-09
US20050234056A1 (en)	2005-10-20
NZ540029A (en)	2007-01-26
CN1726213A (zh)	2006-01-25
ZA200503807B (en)	2006-08-30
CA2505910C (en)	2010-07-13
TWI248934B (en)	2006-02-11
BR0316355A (pt)	2005-09-27
HK1077819A1 (en)	2006-02-24
NO20052866D0 (no)	2005-06-13
EP1560828B1 (en)	2006-05-03
HU0203976D0 (en)	2003-01-28
DE60305058D1 (de)	2006-06-08
SI1560828T1 (sl)	2006-08-31
JP4533148B2 (ja)	2010-09-01
PT1560828E (pt)	2006-08-31
TNSN05133A1 (en)	2007-05-14
RS20050364A (en)	2007-08-03
US7419977B2 (en)	2008-09-02
EA200500830A1 (ru)	2005-10-27
EP1560828A1 (en)	2005-08-10
JP2006515572A (ja)	2006-06-01
IL168516A (en)	2011-05-31
KR20050088291A (ko)	2005-09-05
AU2003282263A1 (en)	2004-06-15
MA27501A1 (fr)	2005-08-01
TW200413369A (en)	2004-08-01
NO20052866L (no)	2005-06-13
MEP19008A (en)	2010-06-10
EA007595B1 (ru)	2006-12-29
CA2505910A1 (en)	2004-06-03
MXPA05005198A (es)	2005-08-18
DE60305058T2 (de)	2006-12-14
AU2003282263B2 (en)	2009-05-14

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