IS5071A - Ný efnasambönd með verkjadeyfandi áhrif - Google Patents

Ný efnasambönd með verkjadeyfandi áhrif

Info

Publication number: IS5071A
Authority: IS; Iceland
Prior art keywords: new compounds; analgesic effect; analgesic; effect; compounds
Prior art date: 1996-12-20

Application number

IS5071A

Other languages

English (en)

Other versions

IS2210B (is

Inventor

Delorme Daniel

Roberts Edward

Wei Zhongyong

Original Assignee

Astra Pharma Inc.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-12-20

Filing date

1999-06-07

Publication date

1999-06-07

1996-12-20 Priority claimed from SE9604785A external-priority patent/SE9604785D0/xx

1997-07-01 Priority claimed from SE9702535A external-priority patent/SE9702535D0/xx

1999-06-07 Application filed by Astra Pharma Inc. filed Critical Astra Pharma Inc.

1999-06-07 Publication of IS5071A publication Critical patent/IS5071A/is

2007-02-15 Publication of IS2210B publication Critical patent/IS2210B/is

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/80—Radicals substituted by oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Rheumatology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Pain & Pain Management (AREA)
Biomedical Technology (AREA)
Physical Education & Sports Medicine (AREA)
Orthopedic Medicine & Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Plural Heterocyclic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

IS5071A 1996-12-20 1999-06-07 Efnasambönd með verkjadeyfandi áhrif sem innihalda alken IS2210B (is)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
SE9604785A SE9604785D0 (sv)	1996-12-20	1996-12-20	New compounds
SE9702535A SE9702535D0 (sv)	1997-07-01	1997-07-01	New compounds
PCT/SE1997/002050 WO1998028275A1 (en)	1996-12-20	1997-12-09	Novel compounds with analgesic effect

Publications (2)

Publication Number	Publication Date
IS5071A true IS5071A (is)	1999-06-07
IS2210B IS2210B (is)	2007-02-15

Family

ID=26662830

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IS5071A IS2210B (is)	1996-12-20	1999-06-07	Efnasambönd með verkjadeyfandi áhrif sem innihalda alken

Country Status (29)

Country	Link
US (5)	US6187792B1 (is)
EP (1)	EP0946511B1 (is)
JP (1)	JP4324652B2 (is)
KR (1)	KR100549144B1 (is)
CN (2)	CN1146540C (is)
AR (1)	AR010376A1 (is)
AT (1)	ATE296288T1 (is)
AU (1)	AU737999B2 (is)
BR (1)	BR9714055B1 (is)
CA (1)	CA2274074C (is)
CZ (1)	CZ295557B6 (is)
DE (1)	DE69733362T2 (is)
EE (1)	EE03824B1 (is)
ES (1)	ES2241060T3 (is)
HK (1)	HK1022689A1 (is)
HU (1)	HU226724B1 (is)
ID (1)	ID22074A (is)
IL (2)	IL130535A0 (is)
IS (1)	IS2210B (is)
MY (1)	MY119403A (is)
NO (1)	NO313670B1 (is)
NZ (1)	NZ336029A (is)
PL (1)	PL189196B1 (is)
PT (1)	PT946511E (is)
RU (1)	RU2193029C2 (is)
SK (1)	SK283211B6 (is)
TR (1)	TR199901417T2 (is)
TW (1)	TW548271B (is)
WO (1)	WO1998028275A1 (is)

Families Citing this family (69)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE9504661D0 (sv)	1995-12-22	1995-12-22	Astra Pharma Inc	New compounds
TW548271B (en)	1996-12-20	2003-08-21	Astra Pharma Inc	Novel piperidine derivatives having an exocyclic double bond with analgesic effects
SE9604786D0 (sv) *	1996-12-20	1996-12-20	Astra Pharma Inc	New compounds
US6436959B1 (en)	1998-12-23	2002-08-20	Ortho-Mcneil Pharmaceutical, Inc.	4-[aryl(piperidin-4-yl)]aminobenzamides
US7361666B2 (en)	1999-05-25	2008-04-22	Sepracor, Inc.	Heterocyclic analgesic compounds and methods of use thereof
US6677332B1 (en)	1999-05-25	2004-01-13	Sepracor, Inc.	Heterocyclic analgesic compounds and methods of use thereof
WO2000071518A2 (en) *	1999-05-25	2000-11-30	Sepracor, Inc.	Heterocyclic analgesic compounds and their use
US6645980B1 (en)	2000-05-25	2003-11-11	Sepracor Inc.	Heterocyclic analgesic compounds and methods of use thereof
US6635661B2 (en)	2000-05-25	2003-10-21	Sepracor Inc.	Heterocyclic analgesic compounds and methods of use thereof
SE9904674D0 (sv)	1999-12-20	1999-12-20	Astra Pharma Inc	Novel compounds
SE9904673D0 (sv)	1999-12-20	1999-12-20	Astra Pharma Inc	Novel compounds
AU2063601A (en)	1999-12-22	2001-07-03	Ortho-Mcneil Pharmaceutical, Inc.	4-(aryl(8-azabicyclo(3.2.1)octan-3-yl))aminobenzoic acid derivatives
CA2400640A1 (en) *	2000-02-18	2001-08-23	Meiji Seika Kaisha, Ltd.	Phenoxyalkylamine derivatives useful as opioid .delta. receptor ligands
CN1426411A (zh) *	2000-03-03	2003-06-25	奥索-麦克尼尔药品公司	3－(二芳基亚甲基)－8－氮杂双环[3.2.1]辛烷衍生物
CA2404280A1 (en)	2000-03-24	2002-09-23	Meiji Seika Kaisha, Ltd.	Diphenylalkylamine derivatives useful as opioid .delta. receptor agonists
SE0001208D0 (sv) *	2000-04-04	2000-04-04	Astrazeneca Canada Inc	Novel compounds
SE0001207D0 (sv) *	2000-04-04	2000-04-04	Astrazeneca Canada Inc	Novel compounds
SE0001209D0 (sv) *	2000-04-04	2000-04-04	Astrazeneca Canada Inc	Novel compounds
WO2002048122A2 (en) *	2000-12-14	2002-06-20	Ortho-Mcneil Pharmaceutical, Inc.	Benzamidine derivatives
SE0101771D0 (sv) *	2001-05-18	2001-05-18	Astrazeneca Ab	Novel compounds
SE0101769D0 (sv) *	2001-05-18	2001-05-18	Astrazeneca Ab	Novel compounds
SE0101773D0 (sv) *	2001-05-18	2001-05-18	Astrazeneca Ab	Novel compounds
WO2002094794A1 (en)	2001-05-18	2002-11-28	Astrazeneca Ab	4 (phenyl-piperazinyl-methyl) benzamide derivatives and their use for the treatment of pain anxiety or gastrointestinal disorders
SE0101767D0 (sv) *	2001-05-18	2001-05-18	Astrazeneca Ab	Novel compounds
SE0101768D0 (sv) *	2001-05-18	2001-05-18	Astrazeneca Ab	Novel compounds
SE0101765D0 (sv) *	2001-05-18	2001-05-18	Astrazeneca Ab	Novel compounds
SE0101770D0 (sv) *	2001-05-18	2001-05-18	Astrazeneca Ab	Novel compounds
SE0101766D0 (sv) *	2001-05-18	2001-05-18	Astrazeneca Ab	Novel compounds
SE0103313D0 (sv) *	2001-10-03	2001-10-03	Astrazeneca Ab	Novel compounds
ATE347549T1 (de)	2001-10-15	2006-12-15	Janssen Pharmaceutica Nv	Neue substituierte 4-phenyl-4-(1h-imidazo-2-yl)- piperidin-derivate und ihre anwendung als selective delta-opioid-agonisten
EP1469850B1 (en) *	2002-01-02	2013-01-02	Versi Group, LLC	Method of treating sexual dysfunctions with delta opioid receptor agonist compounds
US8476280B2 (en) *	2002-05-09	2013-07-02	Versi Group, Llc	Compositions and methods for combating lower urinary tract dysfunctions with delta opioid receptor agonists
UA77536C2 (en) *	2002-07-03	2006-12-15	Lundbeck & Co As H	Secondary aminoaniline piperidines as mch1 antagonists and their use
SE0203302D0 (sv)	2002-11-07	2002-11-07	Astrazeneca Ab	Novel Compounds
SE0203300D0 (sv)	2002-11-07	2002-11-07	Astrazeneca Ab	Novel Compounds
SE0203301D0 (sv) *	2002-11-07	2002-11-07	Astrazeneca Ab	Novel Compounds
SE0203303D0 (sv)	2002-11-07	2002-11-07	Astrazeneca Ab	Novel Compounds
SE0300103D0 (sv)	2003-01-16	2003-01-16	Astrazeneca Ab	Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
SE0300104D0 (sv) *	2003-01-16	2003-01-16	Astrazeneca Ab	Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
SE0300105D0 (sv) *	2003-01-16	2003-01-16	Astrazeneca Ab	Diarylmethylidene piperdine derivatives, preparations thereof and uses thereof
SE0300987D0 (sv) *	2003-04-03	2003-04-03	Astrazeneca Ab	Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
JP2006523673A (ja) *	2003-04-15	2006-10-19	ファイザー・プロダクツ・インク	オピオイド受容体活性を有する３−ベンズヒドリリデン−８−アザ−ビシクロ［３．２．１］オクタン誘導体
SE0301445D0 (sv) *	2003-05-16	2003-05-16	Astrazeneca Ab	Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
RU2005136524A (ru) *	2003-05-16	2006-06-27	Астразенека Аб (Se)	Производные диарилметилиденпиперидина, способы их получения и их применение
SE0301441D0 (sv) *	2003-05-16	2003-05-16	Astrazeneca Ab	Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
SE0301442D0 (sv) *	2003-05-16	2003-05-16	Astrazeneca Ab	Diarylmethylidene piperidine derivatives, preparations therof and uses thereof
SE0301443D0 (sv) *	2003-05-16	2003-05-16	Astrazeneca Ab	Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
WO2004103972A1 (ja) *	2003-05-20	2004-12-02	Ajinomoto Co.,Inc.	新規ピペリジン誘導体
CA2530444C (en)	2003-06-27	2012-03-13	Janssen Pharmaceutica, N.V.	Tricyclic .delta. opioid modulators
NZ545032A (en)	2003-07-28	2009-02-28	Smithkline Beecham Corp	Cycloalkylidene compounds as modulators of estrogen receptor
CN100549004C (zh)	2003-10-01	2009-10-14	阿得罗公司	螺环杂环衍生物及其应用方法
SE0400026D0 (sv) *	2004-01-09	2004-01-09	Astrazeneca Ab	Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
SE0400025D0 (sv) *	2004-01-09	2004-01-09	Astrazeneca Ab	Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
US7435822B2 (en)	2004-02-03	2008-10-14	Janssen Pharmaceutica N.V.	3-(diheteroarylmethylene)-8-azabicyclo[3.2.1]octane and 3-((aryl)(heteroaryl)methylene)-8-azabicyclo[3.2.1]octane derivatives
DK1781631T3 (da)	2004-08-02	2012-05-14	Astrazeneca Ab	Diarylmethylpiperazinderivater, præparater dermed og anvendelser deraf
CN101039940A (zh)	2004-08-05	2007-09-19	詹森药业有限公司	三环δ－阿片样物质调节剂
SE0402485D0 (sv) *	2004-10-13	2004-10-13	Astrazeneca Ab	Polymorph of N,N-Diethyl-4-(3-Fluorophenyl-Piperidin-4-Ylidene-Methyl)-Benzamide Hydrochloride salt
CA2591963A1 (en)	2004-12-22	2006-06-29	Janssen Pharmaceutica N.V.	Tricyclic o-opioid modulators
KR20070087675A (ko)	2004-12-22	2007-08-28	얀센 파마슈티카 엔.브이.	트리사이클릭 δ-오피오이드 모듈레이터
AU2006203880A1 (en)	2005-01-06	2006-07-13	Janssen Pharmaceutica N.V.	Tricyclic delta-opioid modulators
US7557875B2 (en)	2005-03-22	2009-07-07	Industrial Technology Research Institute	High performance flexible display with improved mechanical properties having electrically modulated material mixed with binder material in a ratio between 6:1 and 0.5:1
WO2006113468A2 (en) *	2005-04-14	2006-10-26	Mount Cook Biosciences, Inc.	Compositions of novel opioid compounds and method of use thereof
AU2006259273A1 (en)	2005-06-16	2006-12-28	Janssen Pharmaceutica N.V.	Tricyclic opioid modulators
US7576207B2 (en)	2006-04-06	2009-08-18	Adolor Corporation	Spirocyclic heterocyclic derivatives and methods of their use
CN101534750B (zh) *	2006-09-06	2015-12-16	史密夫和内修有限公司	带有过渡表面的植入物和相关的方法
MY148880A (en) *	2006-10-20	2013-06-14	Astrazeneca Ab	N-(2-hydroxyethyl)-n-methyl-4-(quinolin-8-yl(1-(thiazol-4-ylmethyl)piperidin-4-ylidene)methyl)benzamide, the process of making it as well as its use for the treatment of pain, anxiety and depression
JP2011506292A (ja)	2007-12-06	2011-03-03	シエル・インターナシヨナル・リサーチ・マートスハツペイ・ベー・ヴエー	アルキレングリコールの調製のための方法
CN108139623A (zh) *	2015-06-02	2018-06-08	康宁股份有限公司	美学表面以及具有这种表面的显示设备
CN111825654A (zh) *	2019-04-19	2020-10-27	北京酷瓴生物技术有限公司	苯甲烯哌啶衍生物及其制备方法、中间体和用途

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2898339A (en) *	1957-07-29	1959-08-04	Wm S Merrell Co	N-substituted benzhydrol, benzhydryl, and benzhydrylidene piperidine
US4581171A (en) *	1983-07-27	1986-04-08	Janssen Pharmaceutica, N.V.	[[Bis(aryl)methylene]-1-piperidinyl]alkyl-pyrimidinones useful for treating psychotropic disorders
US4816586A (en) *	1987-07-29	1989-03-28	Regents Of The University Of Minnesota	Delta opioid receptor antagonists
US5140029A (en) *	1989-01-09	1992-08-18	Janssen Pharmaceutica N.V.	2-aminopyrimidinone derivatives
US4939137A (en) *	1989-06-28	1990-07-03	Ortho Pharmaceutical Corporation	Ring-fused thienopyrimidinedione derivatives
US5683998A (en) *	1991-04-23	1997-11-04	Toray Industries, Inc.	Tricyclic triazolo derivatives, processes for producing the same and the uses of the same
GB9202238D0 (en)	1992-02-03	1992-03-18	Wellcome Found	Compounds
US5574159A (en) *	1992-02-03	1996-11-12	Delta Pharmaceuticals, Inc.	Opioid compounds and methods for making therefor
SE9504661D0 (sv)	1995-12-22	1995-12-22	Astra Pharma Inc	New compounds
SE9604786D0 (sv) *	1996-12-20	1996-12-20	Astra Pharma Inc	New compounds
TW548271B (en) *	1996-12-20	2003-08-21	Astra Pharma Inc	Novel piperidine derivatives having an exocyclic double bond with analgesic effects
AU2009799A (en)	1997-12-24	1999-07-19	Ortho-Mcneil Pharmaceutical, Inc.	4-(aryl(piperidin-4-yl)) aminobenzamides which bind to the delta-opioid receptor
SE0001207D0 (sv) *	2000-04-04	2000-04-04	Astrazeneca Canada Inc	Novel compounds
SE0001208D0 (sv) *	2000-04-04	2000-04-04	Astrazeneca Canada Inc	Novel compounds

1997
- 1997-12-08 TW TW086118465A patent/TW548271B/zh not_active IP Right Cessation
- 1997-12-09 EE EEP199900256A patent/EE03824B1/xx not_active IP Right Cessation
- 1997-12-09 JP JP52866998A patent/JP4324652B2/ja not_active Expired - Fee Related
- 1997-12-09 ES ES97950538T patent/ES2241060T3/es not_active Expired - Lifetime
- 1997-12-09 EP EP97950538A patent/EP0946511B1/en not_active Expired - Lifetime
- 1997-12-09 SK SK762-99A patent/SK283211B6/sk not_active IP Right Cessation
- 1997-12-09 AT AT97950538T patent/ATE296288T1/de not_active IP Right Cessation
- 1997-12-09 US US09/029,633 patent/US6187792B1/en not_active Expired - Lifetime
- 1997-12-09 CA CA002274074A patent/CA2274074C/en not_active Expired - Fee Related
- 1997-12-09 WO PCT/SE1997/002050 patent/WO1998028275A1/en active IP Right Grant
- 1997-12-09 HU HU0000610A patent/HU226724B1/hu not_active IP Right Cessation
- 1997-12-09 DE DE69733362T patent/DE69733362T2/de not_active Expired - Lifetime
- 1997-12-09 TR TR1999/01417T patent/TR199901417T2/xx unknown
- 1997-12-09 PT PT97950538T patent/PT946511E/pt unknown
- 1997-12-09 CZ CZ19992199A patent/CZ295557B6/cs not_active IP Right Cessation
- 1997-12-09 AU AU53512/98A patent/AU737999B2/en not_active Ceased
- 1997-12-09 CN CNB971818142A patent/CN1146540C/zh not_active Expired - Fee Related
- 1997-12-09 IL IL13053597A patent/IL130535A0/xx active IP Right Grant
- 1997-12-09 ID IDW990508A patent/ID22074A/id unknown
- 1997-12-09 PL PL97334374A patent/PL189196B1/pl not_active IP Right Cessation
- 1997-12-09 RU RU99115750/04A patent/RU2193029C2/ru not_active IP Right Cessation
- 1997-12-09 BR BRPI9714055-4A patent/BR9714055B1/pt not_active IP Right Cessation
- 1997-12-09 NZ NZ336029A patent/NZ336029A/en unknown
- 1997-12-09 KR KR1019997005585A patent/KR100549144B1/ko not_active IP Right Cessation
- 1997-12-09 CN CNB2004100082366A patent/CN100519528C/zh not_active Expired - Fee Related
- 1997-12-19 AR ARP970106074A patent/AR010376A1/es active IP Right Grant
- 1997-12-19 MY MYPI97006173A patent/MY119403A/en unknown
1999
- 1999-06-07 IS IS5071A patent/IS2210B/is unknown
- 1999-06-17 IL IL130535A patent/IL130535A/en not_active IP Right Cessation
- 1999-06-18 NO NO19993022A patent/NO313670B1/no not_active IP Right Cessation
2000
- 2000-03-11 HK HK00101528A patent/HK1022689A1/xx not_active IP Right Cessation
2001
- 2001-01-18 US US09/761,833 patent/US6455545B2/en not_active Expired - Fee Related
2002
- 2002-08-19 US US10/222,990 patent/US6693117B2/en not_active Expired - Fee Related
2003
- 2003-12-09 US US10/730,265 patent/US7312336B2/en not_active Expired - Fee Related
2007
- 2007-12-05 US US11/951,014 patent/US20080176903A1/en not_active Abandoned

Also Published As

Publication number	Publication date
AU737999B2 (en)	2001-09-06
HU226724B1 (en)	2009-08-28
PL189196B1 (pl)	2005-07-29
JP4324652B2 (ja)	2009-09-02
KR100549144B1 (ko)	2006-02-03
HUP0000610A3 (en)	2000-10-30
CA2274074C (en)	2006-07-11
BR9714055B1 (pt)	2010-02-23
US6693117B2 (en)	2004-02-17
US6455545B2 (en)	2002-09-24
CZ295557B6 (cs)	2005-08-17
CN1146540C (zh)	2004-04-21
KR20000069599A (ko)	2000-11-25
CN100519528C (zh)	2009-07-29
CA2274074A1 (en)	1998-07-02
SK76299A3 (en)	1999-11-08
CN1524852A (zh)	2004-09-01
RU2193029C2 (ru)	2002-11-20
AU5351298A (en)	1998-07-17
IL130535A0 (en)	2000-06-01
ID22074A (id)	1999-09-02
AR010376A1 (es)	2000-06-07
US20010021715A1 (en)	2001-09-13
WO1998028275A1 (en)	1998-07-02
US20040171612A1 (en)	2004-09-02
US6187792B1 (en)	2001-02-13
TR199901417T2 (xx)	1999-10-21
IL130535A (en)	2006-04-10
EE9900256A (et)	1999-12-15
NO993022D0 (no)	1999-06-18
PT946511E (pt)	2005-09-30
EP0946511A1 (en)	1999-10-06
SK283211B6 (sk)	2003-03-04
CN1246111A (zh)	2000-03-01
BR9714055A (pt)	2000-05-09
HK1022689A1 (en)	2000-08-18
TW548271B (en)	2003-08-21
EE03824B1 (et)	2002-08-15
PL334374A1 (en)	2000-02-28
US7312336B2 (en)	2007-12-25
DE69733362D1 (de)	2005-06-30
IS2210B (is)	2007-02-15
CZ219999A3 (cs)	1999-11-17
HUP0000610A2 (hu)	2000-09-28
DE69733362T2 (de)	2006-02-02
JP2001507350A (ja)	2001-06-05
EP0946511B1 (en)	2005-05-25
NO993022L (no)	1999-08-20
MY119403A (en)	2005-05-31
NZ336029A (en)	2001-03-30
US20080176903A1 (en)	2008-07-24
ATE296288T1 (de)	2005-06-15
US20030149023A1 (en)	2003-08-07
ES2241060T3 (es)	2005-10-16
NO313670B1 (no)	2002-11-11

Publication	Publication Date	Title
IS5071A (is)	1999-06-07	Ný efnasambönd með verkjadeyfandi áhrif
IS5078A (is)	1999-06-11	Ný efnasambönd með verkjadeyfandi áhrif
EE9800194A (et)	1998-12-15	Uued valuvaigistava toimega ühendid
PT799819E (pt)	2003-01-31	Compostos de 1-dimetilaminometil-2-fenilcicloalc-2-eno com efeito analgesico
ID15904A (id)	1997-08-14	Senyawa-senyawa tiofenopirimidina
BR9710352A (pt)	1999-08-17	Compostos piridilpirrole
ATE253919T1 (de)	2003-11-15	Analgetika-kombination
DE69716924D1 (de)	2002-12-12	Phosphonat-nukleotid-verbindungen
PT906288E (pt)	2003-02-28	Novos compostos
BR9705635A (pt)	1999-05-18	Compostos
DK0923594T3 (da)	2003-02-10	Bromotiacumicinforbindelser
EE9800195A (et)	1998-12-15	Uudsed analgeetilise toimega ühendid
DE69709659D1 (de)	2002-02-21	Halopropargyl-einschlussverbindungen
IS4932A (is)	1998-12-23	Ný efnasambönd
DK1019042T3 (da)	2003-08-25	Forbindelser med anti-første-passagevirkning
DK0946511T3 (da)	2005-08-22	Hidtil ukendte forbindelser med analgesisk virkning
SE9603464D0 (sv)	1996-09-23	New compounds
SE9601787D0 (sv)	1996-05-10	New compounds
SE9600555D0 (sv)	1996-02-15	New compounds
SE9603505D0 (sv)	1996-09-25	New compounds
SE9604785D0 (sv)	1996-12-20	New compounds
SE9604787D0 (sv)	1996-12-20	New compounds
SE9603470D0 (sv)	1996-09-23	New compounds
SE9604788D0 (sv)	1996-12-20	New compounds
SE9600554D0 (sv)	1996-02-15	New compounds