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SE0300105D0 - Diarylmethylidene piperdine derivatives, preparations thereof and uses thereof - Google Patents

Diarylmethylidene piperdine derivatives, preparations thereof and uses thereof

Info

Publication number
SE0300105D0
SE0300105D0 SE0300105A SE0300105A SE0300105D0 SE 0300105 D0 SE0300105 D0 SE 0300105D0 SE 0300105 A SE0300105 A SE 0300105A SE 0300105 A SE0300105 A SE 0300105A SE 0300105 D0 SE0300105 D0 SE 0300105D0
Authority
SE
Sweden
Prior art keywords
sup
diarylmethylidene
preparations
piperdine derivatives
piperdine
Prior art date
Application number
SE0300105A
Other languages
English (en)
Inventor
William Brown
Andrew Griffin
Christopher Walpole
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Priority to SE0300105A priority Critical patent/SE0300105D0/sv
Publication of SE0300105D0 publication Critical patent/SE0300105D0/sv
Priority to MXPA05007484A priority patent/MXPA05007484A/es
Priority to NZ540758A priority patent/NZ540758A/en
Priority to PCT/GB2004/000099 priority patent/WO2004062562A2/en
Priority to PL378336A priority patent/PL378336A1/pl
Priority to CNB2004800022753A priority patent/CN100422151C/zh
Priority to KR1020057013174A priority patent/KR20050096137A/ko
Priority to UAA200506380A priority patent/UA80012C2/uk
Priority to CA002510382A priority patent/CA2510382A1/en
Priority to US10/541,522 priority patent/US20060154964A1/en
Priority to RU2005121491/04A priority patent/RU2324680C2/ru
Priority to AU2004204390A priority patent/AU2004204390B2/en
Priority to JP2006500202A priority patent/JP2006516559A/ja
Priority to EP04701624A priority patent/EP1587790A2/en
Priority to BR0406614-6A priority patent/BRPI0406614A/pt
Priority to TW093100912A priority patent/TW200504059A/zh
Priority to ARP040100105A priority patent/AR042887A1/es
Priority to IL169366A priority patent/IL169366A0/en
Priority to ZA200505186A priority patent/ZA200505186B/en
Priority to IS7980A priority patent/IS7980A/is
Priority to NO20053809A priority patent/NO20053809L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
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    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P25/36—Opioid-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

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  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Reproductive Health (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Psychology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Communicable Diseases (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Transplantation (AREA)
  • Pregnancy & Childbirth (AREA)
  • Virology (AREA)
SE0300105A 2003-01-16 2003-01-16 Diarylmethylidene piperdine derivatives, preparations thereof and uses thereof SE0300105D0 (sv)

Priority Applications (21)

Application Number Priority Date Filing Date Title
SE0300105A SE0300105D0 (sv) 2003-01-16 2003-01-16 Diarylmethylidene piperdine derivatives, preparations thereof and uses thereof
BR0406614-6A BRPI0406614A (pt) 2003-01-16 2004-01-13 Composto, uso do mesmo, composição farmacêutica, métodos para a terapia de dor em um animal de sangue quente e para a terapia de distúrbios gastrointestinais funcionais em um animal de sangue quente, e, processo para preparar um composto
CA002510382A CA2510382A1 (en) 2003-01-16 2004-01-13 Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
RU2005121491/04A RU2324680C2 (ru) 2003-01-16 2004-01-13 Производные диарилметилиденпиперидина, их применение, способы и промежуточное соединение для их получения
PCT/GB2004/000099 WO2004062562A2 (en) 2003-01-16 2004-01-13 Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
PL378336A PL378336A1 (pl) 2003-01-16 2004-01-13 Pochodne diarylometylidenopiperydyny, ich preparaty i ich zastosowanie
CNB2004800022753A CN100422151C (zh) 2003-01-16 2004-01-13 二芳基亚甲基哌啶衍生物、其制备及其用途
KR1020057013174A KR20050096137A (ko) 2003-01-16 2004-01-13 디아릴메틸리덴 피페리딘 유도체, 그의 제조방법 및 용도
UAA200506380A UA80012C2 (en) 2003-01-16 2004-01-13 Diarylmethylidene piperidine derivatives, preparation thereof and uses thereof
MXPA05007484A MXPA05007484A (es) 2003-01-16 2004-01-13 Derivados de diarilmetilidina piperidina, preparacion y uso de los mismos.
US10/541,522 US20060154964A1 (en) 2003-01-16 2004-01-13 Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
NZ540758A NZ540758A (en) 2003-01-16 2004-01-13 Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
AU2004204390A AU2004204390B2 (en) 2003-01-16 2004-01-13 Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
JP2006500202A JP2006516559A (ja) 2003-01-16 2004-01-13 ジアリールメチリデンピペリジン誘導体、その製造方法及びその使用
EP04701624A EP1587790A2 (en) 2003-01-16 2004-01-13 Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
TW093100912A TW200504059A (en) 2003-01-16 2004-01-14 Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
ARP040100105A AR042887A1 (es) 2003-01-16 2004-01-15 Derivados de diarilmetiden piperidina preparaciones y usos de los mismos
IL169366A IL169366A0 (en) 2003-01-16 2005-06-23 Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
ZA200505186A ZA200505186B (en) 2003-01-16 2005-06-27 Diarylmethylidene piperidine derivatives, preperations thereof and uses thereof
IS7980A IS7980A (is) 2003-01-16 2005-08-12 Díarýlmetýlídenpíperidínafleiður, framleiðsla þeirra og notkun
NO20053809A NO20053809L (no) 2003-01-16 2005-08-12 Diarylmetylindenpiperidinderivater,fremgangsmate for fremstilling derav, og anvendelse derav

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0300105A SE0300105D0 (sv) 2003-01-16 2003-01-16 Diarylmethylidene piperdine derivatives, preparations thereof and uses thereof

Publications (1)

Publication Number Publication Date
SE0300105D0 true SE0300105D0 (sv) 2003-01-16

Family

ID=20290140

Family Applications (1)

Application Number Title Priority Date Filing Date
SE0300105A SE0300105D0 (sv) 2003-01-16 2003-01-16 Diarylmethylidene piperdine derivatives, preparations thereof and uses thereof

Country Status (21)

Country Link
US (1) US20060154964A1 (sv)
EP (1) EP1587790A2 (sv)
JP (1) JP2006516559A (sv)
KR (1) KR20050096137A (sv)
CN (1) CN100422151C (sv)
AR (1) AR042887A1 (sv)
AU (1) AU2004204390B2 (sv)
BR (1) BRPI0406614A (sv)
CA (1) CA2510382A1 (sv)
IL (1) IL169366A0 (sv)
IS (1) IS7980A (sv)
MX (1) MXPA05007484A (sv)
NO (1) NO20053809L (sv)
NZ (1) NZ540758A (sv)
PL (1) PL378336A1 (sv)
RU (1) RU2324680C2 (sv)
SE (1) SE0300105D0 (sv)
TW (1) TW200504059A (sv)
UA (1) UA80012C2 (sv)
WO (1) WO2004062562A2 (sv)
ZA (1) ZA200505186B (sv)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY140070A (en) 2001-05-18 2009-11-30 Astrazeneca Ab 4-(phenyl-piperazinyl-methyl) benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders
SE0203303D0 (sv) 2002-11-07 2002-11-07 Astrazeneca Ab Novel Compounds
SE0203301D0 (sv) * 2002-11-07 2002-11-07 Astrazeneca Ab Novel Compounds
SE0203300D0 (sv) 2002-11-07 2002-11-07 Astrazeneca Ab Novel Compounds
US20070099957A1 (en) * 2003-05-16 2007-05-03 Astra Zeneca Ab Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
NZ546834A (en) 2003-10-01 2010-03-26 Adolor Corp Spirocyclic heterocyclic derivatives and methods of their use
KR101234421B1 (ko) 2004-08-02 2013-02-18 아스트라제네카 아베 디아릴메틸 피페라진 유도체, 이의 제조 방법 및 용도
WO2006091160A1 (en) * 2005-02-28 2006-08-31 Astrazeneca Ab Diarylmethyl piperazine derivatives, preparations thereof and uses thereof
US7598261B2 (en) 2005-03-31 2009-10-06 Adolor Corporation Spirocyclic heterocyclic derivatives and methods of their use
US7576207B2 (en) 2006-04-06 2009-08-18 Adolor Corporation Spirocyclic heterocyclic derivatives and methods of their use
MY148880A (en) * 2006-10-20 2013-06-14 Astrazeneca Ab N-(2-hydroxyethyl)-n-methyl-4-(quinolin-8-yl(1-(thiazol-4-ylmethyl)piperidin-4-ylidene)methyl)benzamide, the process of making it as well as its use for the treatment of pain, anxiety and depression
CN111825654A (zh) * 2019-04-19 2020-10-27 北京酷瓴生物技术有限公司 苯甲烯哌啶衍生物及其制备方法、中间体和用途

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RU2324680C2 (ru) 2008-05-20
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RU2005121491A (ru) 2006-02-10
IS7980A (is) 2005-08-12
WO2004062562A3 (en) 2004-09-16
JP2006516559A (ja) 2006-07-06
IL169366A0 (en) 2007-07-04
BRPI0406614A (pt) 2005-12-06
US20060154964A1 (en) 2006-07-13
WO2004062562A2 (en) 2004-07-29
AU2004204390A1 (en) 2004-07-29
UA80012C2 (en) 2007-08-10
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NZ540758A (en) 2008-03-28
AR042887A1 (es) 2005-07-06
CN1738801A (zh) 2006-02-22
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CN100422151C (zh) 2008-10-01
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EP1587790A2 (en) 2005-10-26
PL378336A1 (pl) 2006-03-20

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