[go: up one dir, main page]

IN2009DN05722A - - Google Patents

Download PDF

Info

Publication number
IN2009DN05722A
IN2009DN05722A IN5722DEN2009A IN2009DN05722A IN 2009DN05722 A IN2009DN05722 A IN 2009DN05722A IN 5722DEN2009 A IN5722DEN2009 A IN 5722DEN2009A IN 2009DN05722 A IN2009DN05722 A IN 2009DN05722A
Authority
IN
India
Prior art keywords
prostate cancer
susceptibility
determining
variants
methods
Prior art date
Application number
Inventor
Gudmundsson Julius
Sulem Patrick
Original Assignee
Decode Genetics Ehf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Decode Genetics Ehf filed Critical Decode Genetics Ehf
Publication of IN2009DN05722A publication Critical patent/IN2009DN05722A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/172—Haplotypes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The present invention is characterised by certain genetic variants being susceptibility variants for prostate cancer. The invention relates to methods of determining increased susceptibility to prostate cancer, as well as methods of determining decreased susceptibility to prostate cancer, using such variants. The invention further relates to kits for determining a susceptibility to prostate cancer.
IN5722DEN2009 2007-02-07 2008-02-07 IN2009DN05722A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IS8604 2007-02-07
IS8654 2007-06-22
PCT/IS2008/000003 WO2008096375A2 (en) 2007-02-07 2008-02-07 Genetic variants contributing to risk of prostate cancer

Publications (1)

Publication Number Publication Date
IN2009DN05722A true IN2009DN05722A (en) 2015-07-24

Family

ID=39650503

Family Applications (1)

Application Number Title Priority Date Filing Date
IN5722DEN2009 IN2009DN05722A (en) 2007-02-07 2008-02-07

Country Status (13)

Country Link
US (1) US8865400B2 (en)
EP (2) EP2522743A3 (en)
JP (1) JP2010520745A (en)
CN (1) CN102317470A (en)
AU (1) AU2008212117B2 (en)
BR (1) BRPI0807236A2 (en)
CA (1) CA2677994A1 (en)
IL (1) IL200197A (en)
IN (1) IN2009DN05722A (en)
MX (1) MX2009008461A (en)
NZ (1) NZ579401A (en)
SG (1) SG193026A1 (en)
WO (1) WO2008096375A2 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8697360B2 (en) * 2007-11-30 2014-04-15 Decode Genetics Ehf. Genetic variants on CHR 11Q and 6Q as markers for prostate and colorectal cancer predisposition
WO2009085196A1 (en) * 2007-12-21 2009-07-09 Wake Forest University Health Sciences Methods and compositions for correlating genetic markers with prostate cancer risk
KR102042253B1 (en) 2010-05-25 2019-11-07 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 Bambam: parallel comparative analysis of high-throughput sequencing data
US9646134B2 (en) * 2010-05-25 2017-05-09 The Regents Of The University Of California Bambam: parallel comparative analysis of high-throughput sequencing data
WO2012029080A1 (en) * 2010-08-30 2012-03-08 Decode Genetics Ehf Sequence variants associated with prostate specific antigen levels
US9732389B2 (en) 2010-09-03 2017-08-15 Wake Forest University Health Sciences Methods and compositions for correlating genetic markers with prostate cancer risk
US9534256B2 (en) 2011-01-06 2017-01-03 Wake Forest University Health Sciences Methods and compositions for correlating genetic markers with risk of aggressive prostate cancer
WO2013037118A1 (en) * 2011-09-16 2013-03-21 上海长海医院 Prostate cancer biomarkers, therapeutic targets and uses thereof
CN103060433B (en) * 2012-10-19 2014-12-03 卫生部北京医院 Kit and method for predicating susceptibility to prostate cancer
JP2016508026A (en) * 2012-11-20 2016-03-17 ファディア・アクチボラゲットＰｈａｄｉａ ＡＢ Prognostic method for individuals with prostate cancer
KR101944927B1 (en) 2016-03-24 2019-02-07 서울대학교산학협력단 Single Nucleotide Polymorphisms Associated With Korean Prostate Cancer And Development Of Genetic Risk Score Using Thereof
WO2017164699A1 (en) * 2016-03-24 2017-09-28 서울대학교병원 (분사무소) Prostate cancer-related single nucleotide polymorphism and development of genetic risk score by using same
KR102068666B1 (en) * 2019-02-28 2020-02-11 주식회사 프로카젠 Ethnic-specific Prostate Cancer Genetic Risk Score Calculating Device, Calculating Method and Recording Medium thereof
KR102068667B1 (en) * 2019-02-28 2020-01-21 주식회사 프로카젠 Prostate Cancer Genetic Risk Score Calculating Device, Calculating Method and Recording Medium thereof
KR102371655B1 (en) * 2019-02-28 2022-03-08 주식회사 프로카젠 Device, Method of Calculating Prostate Cancer Genetic Risk Score Based on Individual Weights for each Genetic Variation and Recording Medium thereof
KR102371654B1 (en) * 2019-02-28 2022-03-08 주식회사 프로카젠 Device, Calculating Method of Calculating Ethnic-specific Prostate Cancer Genetic Risk Score Considering the Predictive Power According to the Number of Genetic Variations and Recording Medium thereof
CN110596060B (en) * 2019-09-12 2020-08-21 江南大学 Construction method and application of fluorescence sensor in spectral analysis for detecting prostate specific antigen

Family Cites Families (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4376110A (en) 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
US5288611A (en) 1983-01-10 1994-02-22 Gen-Probe Incorporated Method for detecting, identifying, and quantitating organisms and viruses
DE3486467T3 (en) 1983-01-10 2004-10-14 Gen-Probe Inc., San Diego Methods for the detection, identification and quantification of organisms and viruses
US5700637A (en) 1988-05-03 1997-12-23 Isis Innovation Limited Apparatus and method for analyzing polynucleotide sequences and method of generating oligonucleotide arrays
US6054270A (en) 1988-05-03 2000-04-25 Oxford Gene Technology Limited Analying polynucleotide sequences
EP0768377A1 (en) 1988-09-02 1997-04-16 Protein Engineering Corporation Generation and selection of recombinant varied binding proteins
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
US5750373A (en) 1990-12-03 1998-05-12 Genentech, Inc. Enrichment method for variant proteins having altered binding properties, M13 phagemids, and growth hormone variants
US5744101A (en) 1989-06-07 1998-04-28 Affymax Technologies N.V. Photolabile nucleoside protecting groups
US5424186A (en) 1989-06-07 1995-06-13 Affymax Technologies N.V. Very large scale immobilized polymer synthesis
US5143854A (en) 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US5288644A (en) 1990-04-04 1994-02-22 The Rockefeller University Instrument and method for the sequencing of genome
US5427908A (en) 1990-05-01 1995-06-27 Affymax Technologies N.V. Recombinant library screening methods
DK0585287T3 (en) 1990-07-10 2000-04-17 Cambridge Antibody Tech Process for producing specific binding pair elements
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
DK0562025T3 (en) 1990-12-06 2001-06-18 Affymetrix Inc Compounds and their use in a binary synthesis strategy
ES2287206T3 (en) 1991-03-01 2007-12-16 Dyax Corporation PROCESS FOR THE DEVELOPMENT OF MINI-PROTEINS OF UNION.
DK1471142T3 (en) 1991-04-10 2009-03-09 Scripps Research Inst Heterodimeric receptor libraries using phagemids
DE4122599C2 (en) 1991-07-08 1993-11-11 Deutsches Krebsforsch Phagemid for screening antibodies
US5384261A (en) 1991-11-22 1995-01-24 Affymax Technologies N.V. Very large scale immobilized polymer synthesis using mechanically directed flow paths
US5858659A (en) 1995-11-29 1999-01-12 Affymetrix, Inc. Polymorphism detection
US5837832A (en) 1993-06-25 1998-11-17 Affymetrix, Inc. Arrays of nucleic acid probes on biological chips
US6287850B1 (en) 1995-06-07 2001-09-11 Affymetrix, Inc. Bioarray chip reaction apparatus and its manufacture
EP0695941B1 (en) 1994-06-08 2002-07-31 Affymetrix, Inc. Method and apparatus for packaging a chip
US6300063B1 (en) 1995-11-29 2001-10-09 Affymetrix, Inc. Polymorphism detection
EP0912761A4 (en) 1996-05-29 2004-06-09 Cornell Res Foundation Inc DETECTION OF DIFFERENCES IN NUCLEIC ACID SEQUENCES USING A COMBINATION OF LIGASE DETECTION AND POLYMERASE CHAIN AMPLIFICATION REACTIONS
US5925519A (en) * 1996-06-03 1999-07-20 The Regents Of The University Of California Genetic alterations associated with prostate cancer
EP1084239B1 (en) * 1998-06-05 2008-09-24 Serono Genetics Institute S.A. Polymorphic markers of prostate carcinoma tumor antigen-1 (pcta-1)
US6355623B2 (en) 1998-09-24 2002-03-12 Hopital-Sainte-Justine Method of treating IBD/Crohn's disease and related conditions wherein drug metabolite levels in host blood cells determine subsequent dosage
KR20020013477A (en) * 1998-11-06 2002-02-20 미리어드 제네틱스, 인크. Chromosome 17p-Linked Prostate Cancer Susceptibility Gene
US6429027B1 (en) 1998-12-28 2002-08-06 Illumina, Inc. Composite arrays utilizing microspheres
EP1585433A4 (en) * 2002-09-25 2008-01-23 Ge Healthcare Sv Corp Detection methods
US20050136407A1 (en) * 2003-12-19 2005-06-23 Cramer Scott D. Genetic polymorphisms in the prostate-specific antigen gene promoter
US20050255507A1 (en) * 2004-02-17 2005-11-17 Jenkins Robert B Cytogenetically determined diagnosis and prognosis of proliferative disorders
WO2006063285A2 (en) * 2004-12-10 2006-06-15 Sequenom, Inc. Methods for identifying risk of breast cancer or prostate cancer and treatments thereof
EP1888772A1 (en) 2005-05-18 2008-02-20 Decode Genetics EHF. Variants at chr8q24.21 confer risk of cancer
SG175680A1 (en) 2006-10-27 2011-11-28 Decode Genetics Ehf Cancer susceptibility variants on chr8q24.21
US8697360B2 (en) 2007-11-30 2014-04-15 Decode Genetics Ehf. Genetic variants on CHR 11Q and 6Q as markers for prostate and colorectal cancer predisposition

Also Published As

Publication number Publication date
EP2115171A2 (en) 2009-11-11
CA2677994A1 (en) 2008-08-14
SG193026A1 (en) 2013-09-30
WO2008096375A3 (en) 2008-12-18
EP2115171B1 (en) 2015-01-21
MX2009008461A (en) 2009-08-17
EP2522743A3 (en) 2013-08-07
BRPI0807236A2 (en) 2019-09-24
EP2522743A2 (en) 2012-11-14
NZ579401A (en) 2012-03-30
WO2008096375A2 (en) 2008-08-14
IL200197A0 (en) 2010-04-29
CN102317470A (en) 2012-01-11
US8865400B2 (en) 2014-10-21
AU2008212117A1 (en) 2008-08-14
IL200197A (en) 2014-07-31
JP2010520745A (en) 2010-06-17
AU2008212117B2 (en) 2014-09-11
US20100041037A1 (en) 2010-02-18

Similar Documents

Publication Publication Date Title
IN2009DN05722A (en)
GB2460769A (en) Tle3 as a marker for chemotherapy
AU2016204376A1 (en) MicroRNA-based methods and compositions for the diagnosis and treatment of ovarian cancer
MX340453B (en) Biomarkers for lung cancer.
MX340181B (en) Downy mildew resistant cucumber plants.
WO2008154249A3 (en) Gene expression markers of tumor resistance to her2 inhibitor treatment
ATE522518T1 (en) INDAZOLE AND ISOINDOLE DERIVATIVES AS GLUCOKINASE ACTIVATE SUBSTANCES
MX2011013243A (en) Risk markers for cardiovascular disease.
WO2009134487A3 (en) Optimized methods for delivery of dsrna targeting the pcsk9 gene
PT1893196E (en) DIARIL-HYDANTOIN COMPOUND
MY150542A (en) Cmet inhibitors
MX360301B (en) Boron-containing small molecules as anti-inflammatory agents.
MX2011011431A (en) Composition for the treatment of prostate cancer.
MX2009007695A (en) Iron-hydrocarbon complex compounds.
EP2516624A4 (en) CELL LINE 3M
MY156954A (en) PROCESS FOR PREPARING SUBSTITUTED 1-O-ACYL-2-DEOXY-2-FLUORO-4-THIO-ß-D-ARABINOFURANOSES
WO2012083969A3 (en) Microrna for diagnosis of pancreatic cancer
MX2009004167A (en) Antibodies that bind cxcr7 epitopes.
MX337203B (en) Novel jnk inhibitor molecules.
MX339300B (en) Small molecule inhibitors of n-terminus activation of the androgen receptor.
LT2012062A (en) Compositions, methods and related uses for cleaving modified dna
IN2014KN01062A (en)
MX350807B (en) Compositions and methods for prostate cancer analysis.
MX2009006943A (en) Method for the improved utilization of the production potential of transgenic plants.
PH12012501153A1 (en) Process for synthesis of intermediates useful for making substituted indazole and azaindazole compounds