IL97148A0 - Oxetanones,their manufacture and pharmaceutical compositions containing them - Google Patents
Oxetanones,their manufacture and pharmaceutical compositions containing themInfo
- Publication number
- IL97148A0 IL97148A0 IL97148A IL9714891A IL97148A0 IL 97148 A0 IL97148 A0 IL 97148A0 IL 97148 A IL97148 A IL 97148A IL 9714891 A IL9714891 A IL 9714891A IL 97148 A0 IL97148 A0 IL 97148A0
- Authority
- IL
- Israel
- Prior art keywords
- oxetanones
- manufacture
- pharmaceutical compositions
- compositions containing
- novel
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/02—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D305/10—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms not condensed with other rings having one or more double bonds between ring members or between ring members and non-ring members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/02—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D305/10—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms not condensed with other rings having one or more double bonds between ring members or between ring members and non-ring members
- C07D305/12—Beta-lactones
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Child & Adolescent Psychology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Epoxy Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Polyesters Or Polycarbonates (AREA)
Abstract
Novel oxetanones inhibiting pancreatic lipase, of the formula <IMAGE> in which Q, R<1> and R<2> have the meaning given in the description, are disclosed, which are prepared starting from the corresponding beta -hydroxycarboxylic acids.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH60490 | 1990-02-26 | ||
| CH400590 | 1990-12-17 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL97148A0 true IL97148A0 (en) | 1992-05-25 |
| IL97148A IL97148A (en) | 1996-11-14 |
Family
ID=25685091
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL9714891A IL97148A (en) | 1990-02-26 | 1991-02-05 | Oxetanones a process for their manufacture and pharmaceutical compositions containing them |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP0444482B1 (en) |
| JP (1) | JP2753403B2 (en) |
| KR (1) | KR0183036B1 (en) |
| AT (1) | ATE133167T1 (en) |
| AU (1) | AU645291B2 (en) |
| CA (1) | CA2035967C (en) |
| DE (1) | DE59107262D1 (en) |
| DK (1) | DK0444482T3 (en) |
| ES (1) | ES2082869T3 (en) |
| FI (1) | FI115054B (en) |
| GR (1) | GR3019618T3 (en) |
| HU (1) | HU218272B (en) |
| IE (1) | IE72196B1 (en) |
| IL (1) | IL97148A (en) |
| MC (1) | MC2226A1 (en) |
| NO (1) | NO177055C (en) |
| NZ (1) | NZ237170A (en) |
| PT (1) | PT96887B (en) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2035972C (en) * | 1990-02-23 | 2006-07-11 | Martin Karpf | Process for the preparation of oxetanones |
| CA2098167C (en) * | 1992-06-24 | 2006-12-19 | Dorothea Isler | Foodstuffs and feedstuffs containing a lipase inhibitor |
| NL1004559C2 (en) * | 1996-11-18 | 1998-05-19 | Unilife | Butter. |
| MXPA01006755A (en) * | 1999-10-29 | 2003-05-15 | Jason Gentry Mullins John | Oxetanone derivatives. |
| US6342519B2 (en) * | 1999-10-29 | 2002-01-29 | 2 Pro Chemical | Oxetanone derivatives |
| US6348492B1 (en) * | 1999-10-29 | 2002-02-19 | 2Pro Chemical | Oxetanone derivatives |
| DE102004009076A1 (en) * | 2004-02-23 | 2005-10-27 | Solvay Pharmaceuticals Gmbh | Alkylcarbamate-substituted β-lactones, processes and intermediates for their preparation, and medicaments containing these compounds |
| US7074822B2 (en) | 2004-02-23 | 2006-07-11 | Solvay Pharmaceuticals Gmbh | Alkyl carbamate-substituted β-lactones, process for their preparation, and pharmaceutical compositions containing them |
| JP2011502167A (en) | 2007-10-31 | 2011-01-20 | バーンハム インスティテュート フォー メディカル リサーチ | β-lactone compounds |
| JP7224331B2 (en) * | 2017-07-12 | 2023-02-17 | メイヨ・ファウンデーション・フォー・メディカル・エデュケーション・アンド・リサーチ | Compounds for reduction of lipotoxic damage |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS608117B2 (en) * | 1977-02-08 | 1985-02-28 | 財団法人微生物化学研究会 | New physiologically active substance esterastin and its production method |
| GB2023604B (en) * | 1978-05-25 | 1982-07-28 | Microbial Chem Res Found | Physiologically active derivatives of esterastin and production thereof |
| JPH0669130B2 (en) * | 1984-08-09 | 1994-08-31 | 三菱電機株式会社 | Delay line |
-
1991
- 1991-02-05 IL IL9714891A patent/IL97148A/en active IP Right Grant
- 1991-02-07 CA CA002035967A patent/CA2035967C/en not_active Expired - Fee Related
- 1991-02-15 EP EP91102151A patent/EP0444482B1/en not_active Expired - Lifetime
- 1991-02-15 DE DE59107262T patent/DE59107262D1/en not_active Expired - Fee Related
- 1991-02-15 DK DK91102151.7T patent/DK0444482T3/en not_active Application Discontinuation
- 1991-02-15 ES ES91102151T patent/ES2082869T3/en not_active Expired - Lifetime
- 1991-02-15 AT AT91102151T patent/ATE133167T1/en not_active IP Right Cessation
- 1991-02-20 NZ NZ237170A patent/NZ237170A/en unknown
- 1991-02-20 HU HU61/91A patent/HU218272B/en not_active IP Right Cessation
- 1991-02-20 AU AU71228/91A patent/AU645291B2/en not_active Ceased
- 1991-02-21 MC MC912172A patent/MC2226A1/en unknown
- 1991-02-22 JP JP3131730A patent/JP2753403B2/en not_active Expired - Fee Related
- 1991-02-25 IE IE63191A patent/IE72196B1/en not_active IP Right Cessation
- 1991-02-25 NO NO910729A patent/NO177055C/en unknown
- 1991-02-26 FI FI910925A patent/FI115054B/en not_active IP Right Cessation
- 1991-02-26 PT PT96887A patent/PT96887B/en not_active IP Right Cessation
- 1991-02-26 KR KR1019910003075A patent/KR0183036B1/en not_active IP Right Cessation
-
1996
- 1996-04-09 GR GR960401013T patent/GR3019618T3/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0444482A2 (en) | 1991-09-04 |
| ATE133167T1 (en) | 1996-02-15 |
| JP2753403B2 (en) | 1998-05-20 |
| EP0444482A3 (en) | 1991-12-04 |
| KR910021391A (en) | 1991-12-20 |
| AU7122891A (en) | 1991-08-29 |
| KR0183036B1 (en) | 1999-05-01 |
| IE910631A1 (en) | 1991-08-28 |
| GR3019618T3 (en) | 1996-07-31 |
| FI910925A (en) | 1991-08-27 |
| ES2082869T3 (en) | 1996-04-01 |
| HUT56557A (en) | 1991-09-30 |
| MC2226A1 (en) | 1993-02-02 |
| CA2035967C (en) | 2001-10-16 |
| FI910925A0 (en) | 1991-02-26 |
| NO910729L (en) | 1991-08-27 |
| JPH0770099A (en) | 1995-03-14 |
| IE72196B1 (en) | 1997-03-26 |
| FI115054B (en) | 2005-02-28 |
| PT96887B (en) | 1998-09-30 |
| PT96887A (en) | 1991-10-31 |
| HU218272B (en) | 2000-07-28 |
| NO910729D0 (en) | 1991-02-25 |
| NZ237170A (en) | 1993-12-23 |
| EP0444482B1 (en) | 1996-01-17 |
| DK0444482T3 (en) | 1996-05-06 |
| NO177055C (en) | 1995-07-12 |
| CA2035967A1 (en) | 1991-08-27 |
| IL97148A (en) | 1996-11-14 |
| AU645291B2 (en) | 1994-01-13 |
| DE59107262D1 (en) | 1996-02-29 |
| NO177055B (en) | 1995-04-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| KB | Patent renewed |