IL85004A - 1,4 dihydro-beta-oxo-1-substituted-(1)-benzo(thio)-pyrano-(4,3-c)pyrazole-3-poropanenitrile derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

1,4 dihydro-beta-oxo-1-substituted-(1)-benzo(thio)-pyrano-(4,3-c)pyrazole-3-poropanenitrile derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number: IL85004A
Authority: IL; Israel
Prior art keywords: poropanenitrile; pyrano; pyrazole; benzo; thio
Prior art date: 1987-01-09

Application number

IL85004A

Other languages

English (en)

Other versions

IL85004A0 (en

Original Assignee

Erba Carlo Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-01-09

Filing date

1988-01-01

Publication date

1991-11-21

1987-01-09 Priority claimed from GB878700477A external-priority patent/GB8700477D0/en

1987-07-22 Priority claimed from GB878717282A external-priority patent/GB8717282D0/en

1988-01-01 Application filed by Erba Carlo Spa filed Critical Erba Carlo Spa

1988-06-30 Publication of IL85004A0 publication Critical patent/IL85004A0/xx

1991-11-21 Publication of IL85004A publication Critical patent/IL85004A/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Immunology (AREA)
Public Health (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Virology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Molecular Biology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Hydrogenated Pyridines (AREA)
Pyridine Compounds (AREA)

IL85004A 1987-01-09 1988-01-01 1,4 dihydro-beta-oxo-1-substituted-(1)-benzo(thio)-pyrano-(4,3-c)pyrazole-3-poropanenitrile derivatives,their preparation and pharmaceutical compositions containing them IL85004A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB878700477A GB8700477D0 (en)	1987-01-09	1987-01-09	Heteroaryl 2-cyano-3-oxo-propanamide derivatives
GB878717282A GB8717282D0 (en)	1987-07-22	1987-07-22	Heteroaryl 3-oxo-propanenitrile derivatives

Publications (2)

Publication Number	Publication Date
IL85004A0 IL85004A0 (en)	1988-06-30
IL85004A true IL85004A (en)	1991-11-21

Family

ID=26291768

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL85004A IL85004A (en)	1987-01-09	1988-01-01	1,4 dihydro-beta-oxo-1-substituted-(1)-benzo(thio)-pyrano-(4,3-c)pyrazole-3-poropanenitrile derivatives,their preparation and pharmaceutical compositions containing them

Country Status (23)

Country	Link
US (1)	US4816467A (no)
EP (1)	EP0274443B1 (no)
JP (1)	JP2672312B2 (no)
KR (1)	KR960002852B1 (no)
CN (1)	CN1025500C (no)
AU (1)	AU598893B2 (no)
CA (1)	CA1310647C (no)
CZ (1)	CZ277972B6 (no)
DE (1)	DE3862937D1 (no)
DK (1)	DK8088A (no)
ES (1)	ES2029003T3 (no)
FI (1)	FI89489C (no)
GR (1)	GR3002032T3 (no)
HU (1)	HU198722B (no)
IE (1)	IE60620B1 (no)
IL (1)	IL85004A (no)
MY (1)	MY103348A (no)
NO (1)	NO165841C (no)
NZ (1)	NZ223113A (no)
PH (1)	PH27000A (no)
PT (1)	PT86516B (no)
SU (1)	SU1695826A3 (no)
YU (2)	YU46787B (no)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0286346B1 (en) *	1987-04-09	1994-04-06	E.I. Du Pont De Nemours And Company	Insecticidal substituted indazoles
GB8814587D0 (en) *	1988-06-20	1988-07-27	Erba Carlo Spa	Condensed pyrazole 3-oxo-propanenitrile derivatives & process for their preparation
GB8814586D0 (en) *	1988-06-20	1988-07-27	Erba Carlo Spa	Tricyclic 3-oxo-propanenitrile derivatives & process for their preparation
GB2227741B (en) *	1989-02-06	1992-08-05	Erba Carlo Spa	Condensed 3-oxo-propanenitrile derivatives and process for their preparation
US5260328A (en) *	1989-04-06	1993-11-09	Farmitalia Carlo Erba Srl	Phenyl-indenopurazol 3-oxo-propanamide derivatives useful in the treatment of rheumatoid arthritis
GB8907799D0 (en) *	1989-04-06	1989-05-17	Erba Carlo Spa	Heteroaryl-3-oxo-propanenitrile derivatives useful in the treatment of rheumatoid arthritis and other autoimmune diseases
GB8916290D0 (en) *	1989-07-17	1989-08-31	Erba Carlo Spa	Heteroaryl-3-oxo-propanenitrile derivatives useful in stimulating myelopoiesis
DK0527736T3 (da) *	1990-05-18	1997-10-20	Hoechst Ag	Isoxazol-4-carboxylsyreamider og hydroxyalkyliden-cyanoacetamider, lægemidler indeholdende disse forbindelser og anvendelsen af disse lægemidler.
US5547975A (en) *	1994-09-20	1996-08-20	Talley; John J.	Benzopyranopyrazolyl derivatives for the treatment of inflammation
US5886016A (en) *	1995-09-15	1999-03-23	G.D. Searle & Co.	Benzopyranopyrazolyl derivatives for the treatment of inflammation
GB9720899D0 (en) *	1997-10-01	1997-12-03	Pharmacia & Upjohn Spa	Condensed heterocyclic compounds
AU2001247616B2 (en) *	2000-04-11	2007-06-14	Genentech, Inc.	Multivalent antibodies and uses therefor
BR0212617A (pt) *	2001-09-19	2005-02-09	Pharmacia Corp	Compostos de pirazolila substituìdo para o tratamento de inflamação
CA2534426A1 (en) *	2003-08-08	2005-02-17	Barnes-Jewish Hospital	Emulsion particles for imaging and therapy and methods of use thereof
US20060035242A1 (en)	2004-08-13	2006-02-16	Michelitsch Melissa D	Prion-specific peptide reagents
EP2019667A4 (en) *	2006-04-27	2012-08-22	Barnes Jewish Hospital	DETECTION AND IMAGING OF TARGET TISSUE
US9073940B2 (en) *	2009-11-13	2015-07-07	Merck Serono Sa	Tricyclic pyrazol amine derivatives
CN102086212B (zh) *	2009-12-03	2013-06-12	沈阳药科大学	抗真菌剂-2，3，4，5-四氢-4H-苯并[b]噻喃并[4，3-c]吡唑-2-甲酰胺衍生物
US11149082B2 (en)	2016-10-17	2021-10-19	University Of Maryland, College Park	Multispecific antibodies targeting human immunodeficiency virus and methods of using the same

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4268516A (en) *	1978-10-11	1981-05-19	Pfizer Inc.	[1]Benzothiopyrano[4,3-c]pyrazoles as immunoregulatory agents
EP0022446A1 (de) *	1979-04-06	1981-01-21	F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft	Verfahren zur Herstellung von Biotinestern und von Biotin
AU8029982A (en) *	1981-02-11	1982-08-19	E.I. Du Pont De Nemours And Company	3,4-dihydro-(1,4-dihydro)-2 substituted-thio benzopyrano 3,4-d imidazoles
PH21213A (en) *	1984-10-26	1987-08-21	Fujisawa Pharmaceutical Co	Benzene- and pyrazole- fused heterocyclic compound and pharmaceutical composition comprising the same

1987
- 1987-12-31 US US07/140,221 patent/US4816467A/en not_active Expired - Fee Related
1988
- 1988-01-01 IL IL85004A patent/IL85004A/xx not_active IP Right Cessation
- 1988-01-04 PH PH36319A patent/PH27000A/en unknown
- 1988-01-04 IE IE288A patent/IE60620B1/en not_active IP Right Cessation
- 1988-01-05 AU AU10037/88A patent/AU598893B2/en not_active Ceased
- 1988-01-06 YU YU1088A patent/YU46787B/sh unknown
- 1988-01-07 NZ NZ223113A patent/NZ223113A/xx unknown
- 1988-01-07 CZ CS88179A patent/CZ277972B6/cs not_active IP Right Cessation
- 1988-01-07 CN CN88100153A patent/CN1025500C/zh not_active Expired - Fee Related
- 1988-01-07 CA CA000556010A patent/CA1310647C/en not_active Expired - Lifetime
- 1988-01-08 ES ES198888300115T patent/ES2029003T3/es not_active Expired - Lifetime
- 1988-01-08 EP EP88300115A patent/EP0274443B1/en not_active Expired - Lifetime
- 1988-01-08 DK DK008088A patent/DK8088A/da not_active Application Discontinuation
- 1988-01-08 KR KR1019880000056A patent/KR960002852B1/ko active IP Right Grant
- 1988-01-08 FI FI880078A patent/FI89489C/fi not_active IP Right Cessation
- 1988-01-08 DE DE8888300115T patent/DE3862937D1/de not_active Expired - Lifetime
- 1988-01-08 PT PT86516A patent/PT86516B/pt not_active IP Right Cessation
- 1988-01-08 HU HU8858A patent/HU198722B/hu not_active IP Right Cessation
- 1988-01-08 MY MYPI88000014A patent/MY103348A/en unknown
- 1988-01-08 NO NO880068A patent/NO165841C/no unknown
- 1988-01-08 JP JP63002374A patent/JP2672312B2/ja not_active Expired - Lifetime
- 1988-01-08 SU SU884355070A patent/SU1695826A3/ru active
1989
- 1989-04-18 YU YU00794/89A patent/YU79489A/xx unknown
1991
- 1991-05-30 GR GR91400684T patent/GR3002032T3/el unknown

Also Published As

Publication number	Publication date
YU1088A (en)	1989-08-31
AU598893B2 (en)	1990-07-05
YU79489A (en)	1989-10-31
KR880008987A (ko)	1988-09-13
NO880068D0 (no)	1988-01-08
JPS63174988A (ja)	1988-07-19
FI89489C (fi)	1993-10-11
CA1310647C (en)	1992-11-24
KR960002852B1 (ko)	1996-02-27
FI880078A (fi)	1988-07-10
IE60620B1 (en)	1994-07-27
FI880078A0 (fi)	1988-01-08
US4816467A (en)	1989-03-28
DK8088D0 (da)	1988-01-08
PT86516B (pt)	1991-12-31
EP0274443B1 (en)	1991-05-29
MY103348A (en)	1993-06-30
CZ17988A3 (en)	1993-02-17
ES2029003T3 (es)	1992-07-16
NZ223113A (en)	1989-07-27
IE880002L (en)	1988-07-09
CN1025500C (zh)	1994-07-20
HU198722B (en)	1989-11-28
CN88100153A (zh)	1988-07-27
DE3862937D1 (de)	1991-07-04
NO165841B (no)	1991-01-07
EP0274443A1 (en)	1988-07-13
IL85004A0 (en)	1988-06-30
DK8088A (da)	1988-07-10
PT86516A (en)	1988-02-01
JP2672312B2 (ja)	1997-11-05
YU46787B (sh)	1994-06-10
GR3002032T3 (en)	1992-12-30
PH27000A (en)	1993-02-01
AU1003788A (en)	1988-07-14
SU1695826A3 (ru)	1991-11-30
CZ277972B6 (en)	1993-07-14
NO165841C (no)	1991-04-17
HUT47113A (en)	1989-01-30
FI89489B (fi)	1993-06-30
NO880068L (no)	1988-07-11

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Legal Events

Date	Code	Title	Description
1998-06-15	KB	Patent renewed
2002-09-12	MM9K	Patent not in force due to non-payment of renewal fees