IL72565A - Fast release pharmaceutical composition containing isopropyl 6-cyano-5-methoxycarbonyl-2-methyl-4-(3-nitrophenyl)-1,4-dihydro-pyridine-3-carboxylate-and process for the preparation thereof - Google Patents

Fast release pharmaceutical composition containing isopropyl 6-cyano-5-methoxycarbonyl-2-methyl-4-(3-nitrophenyl)-1,4-dihydro-pyridine-3-carboxylate-and process for the preparation thereof

Info

Publication number: IL72565A
Authority: IL; Israel
Prior art keywords: methoxycarbonyl; nitrophenyl; dihydro; carboxylate; cyano
Prior art date: 1983-08-11

Application number

IL72565A

Other languages

English (en)

Other versions

IL72565A0 (en

Original Assignee

Fujisawa Pharmaceutical Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-08-11

Filing date

1984-08-02

Publication date

1988-01-31

1984-08-02 Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co

1984-11-30 Publication of IL72565A0 publication Critical patent/IL72565A0/xx

1988-01-31 Publication of IL72565A publication Critical patent/IL72565A/xx

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)

IL72565A 1983-08-11 1984-08-02 Fast release pharmaceutical composition containing isopropyl 6-cyano-5-methoxycarbonyl-2-methyl-4-(3-nitrophenyl)-1,4-dihydro-pyridine-3-carboxylate-and process for the preparation thereof IL72565A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP58147871A JPS6038322A (ja)	1983-08-11	1983-08-11	ジヒドロピリジンａ物質含有易溶性固形製剤

Publications (2)

Publication Number	Publication Date
IL72565A0 IL72565A0 (en)	1984-11-30
IL72565A true IL72565A (en)	1988-01-31

Family

ID=15440116

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL72565A IL72565A (en)	1983-08-11	1984-08-02	Fast release pharmaceutical composition containing isopropyl 6-cyano-5-methoxycarbonyl-2-methyl-4-(3-nitrophenyl)-1,4-dihydro-pyridine-3-carboxylate-and process for the preparation thereof

Country Status (24)

Country	Link
US (1)	US4654206A (xx)
EP (1)	EP0137198B1 (xx)
JP (1)	JPS6038322A (xx)
KR (1)	KR910003559B1 (xx)
AT (1)	AT382779B (xx)
AU (1)	AU564506B2 (xx)
BE (1)	BE900348A (xx)
CA (1)	CA1228815A (xx)
CH (1)	CH660967A5 (xx)
DE (1)	DE3484259D1 (xx)
DK (1)	DK164020C (xx)
ES (1)	ES8601686A1 (xx)
FI (1)	FI83839C (xx)
FR (1)	FR2550444B1 (xx)
GB (1)	GB2145332B (xx)
GR (1)	GR80004B (xx)
HK (1)	HK6688A (xx)
IE (1)	IE57757B1 (xx)
IL (1)	IL72565A (xx)
IT (1)	IT1183062B (xx)
MY (1)	MY100042A (xx)
PH (1)	PH21551A (xx)
SG (1)	SG73087G (xx)
ZA (1)	ZA845844B (xx)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3424553A1 (de) *	1984-07-04	1986-01-09	Bayer Ag, 5090 Leverkusen	Feste arzneizubereitungen mit dihydropyridinen und verfahren zu ihrer herstellung
GB8608080D0 (en) *	1986-04-02	1986-05-08	Fujisawa Pharmaceutical Co	Solid dispersion composition
DE3887179T2 (de) *	1987-03-02	1994-06-16	Brocades Pharma Bv	Pharmazeutische Zusammensetzung, pharmazeutisches Granulat und Verfahren zu ihrer Herstellung.
US5045553A (en) *	1987-06-24	1991-09-03	Fujisawa Pharmaceutical Company, Ltd.	Pharmaceutical composition for percutaneous drug absorption and percutaneous drug absorption promoter
DE3720757A1 (de) *	1987-06-24	1989-01-05	Bayer Ag	Dhp-manteltablette
NO883326L (no) *	1987-08-11	1989-02-13	Bayer Ag	Dhp-retard-tilberedning.
ATE84213T1 (de) *	1987-11-11	1993-01-15	Pharmascience Lab	Exifon und ein wasserloesliches polymer enthaltende pharmazeutische zubereitung.
JPH02206A (ja) *	1987-11-11	1990-01-05	Fujisawa Pharmaceut Co Ltd	エキシホンと水溶性高分子化合物とを含有することを特徴とする新規製剤
FR2640137A1 (fr) *	1988-12-08	1990-06-15	Texinfine Sa	Systemes transporteurs de principes actifs lipophiles et leur procede d'obtention
JPH0347124A (ja) *	1989-04-20	1991-02-28	Fujisawa Pharmaceut Co Ltd	経口吸収用製剤
WO1991007385A1 (en) *	1989-11-18	1991-05-30	Schering Agrochemicals Limited	Preparation of propenoic acid derivatives
JP3110794B2 (ja) *	1991-06-05	2000-11-20	ユーシービージャパン株式会社	１，４−ジヒドロピリジン誘導体を含有する製剤
US5340591A (en) *	1992-01-24	1994-08-23	Fujisawa Pharmaceutical Co., Ltd.	Method of producing a solid dispersion of the sparingly water-soluble drug, nilvadipine
DK0557244T3 (da) *	1992-02-17	1996-04-01	Siegfried Ag Pharma	Dosisformer med forlænget afgivelse af aktivt stof
IL104192A (en) *	1992-02-17	1998-01-04	Siegfried Ag Pharma	Pharmaceutical dosage forms having prolonged release rate of zero order of the active ingredient
DE4316537A1 (de) *	1993-05-18	1994-11-24	Basf Ag	Zubereitungen in Form fester Lösungen
US5871776A (en) *	1995-01-31	1999-02-16	Mehta; Atul M.	Controlled-release nifedipine
DE19511131A1 (de) *	1995-03-27	1996-10-02	Basf Ag	Mechanisch stabile feste Wirkstoffzubereitungsformen
TW487582B (en) *	1995-08-11	2002-05-21	Nissan Chemical Ind Ltd	Method for converting sparingly water-soluble medical substance to amorphous state
WO1997034601A1 (fr) *	1996-03-18	1997-09-25	Eisai Co., Ltd.	Compositions medicamenteuses a solubilite amelioree
HN1998000115A (es) *	1997-08-21	1999-06-02	Warner Lambert Co	Formas de dosificación farmacéuticas sólidas
US6555139B2 (en)	1999-06-28	2003-04-29	Wockhardt Europe Limited	Preparation of micron-size pharmaceutical particles by microfluidization
JP2003146878A (ja) *	2002-11-22	2003-05-21	Sawai Pharmaceutical Co Ltd	ニルバジピン含有易溶性固形製剤およびその製造法
WO2004110354A2 (en) *	2003-05-15	2004-12-23	Roskamp Research, Llc	Method for reducing amyloid deposition, amyloid neurotoxicity and microgliosis
TWI346114B (en) *	2003-09-29	2011-08-01		Method for stabilization of diarylvinylene compounds
CN100563658C (zh)	2003-11-14	2009-12-02	味之素株式会社	苯丙氨酸衍生物的固体分散体或固体分散体医药制剂
JP5411145B2 (ja) *	2007-10-05	2014-02-12	アルツハイマーズ・インスティテュート・オブ・アメリカ・インコーポレイテッド	（−）−ニルバジピンエナンチオマーによってアミロイド沈着、アミロイド神経毒性、およびミクログリオーシスを減少させる方法
US20100093810A1 (en) *	2007-10-05	2010-04-15	Alzheimer's Institute Of America, Inc.	Pharmaceutical Compositions for Reducing Amyloid Deposition, Amyloid Neurotoxicity, and Microgliosis
US20150011549A1 (en) *	2012-02-15	2015-01-08	Takeda Pharmaceutical Company Limited	Tablet
KR20190050784A (ko) *	2016-09-07	2019-05-13	사니오나 에이/에스	테소펜신 조성물

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3852421A (en) *	1970-03-23	1974-12-03	Shinetsu Chemical Co	Excipient and shaped medicaments prepared therewith
GB1593261A (en) *	1976-07-23	1981-07-15	Inveresk Res Int	Controlled release suppository
GB1579818A (en) *	1977-06-07	1980-11-26	Yamanouchi Pharma Co Ltd	Nifedipine-containing solid preparation composition
CA1117117A (en) *	1978-10-10	1982-01-26	Fujisawa Pharmaceutical Co., Ltd.	2-methyl-dihydropyridine compound, processes for preparation thereof and pharmaceutical composition comprising the same
DE3013839A1 (de) *	1979-04-13	1980-10-30	Freunt Ind Co Ltd	Verfahren zur herstellung einer aktivierten pharmazeutischen zusammensetzung
CA1146866A (en) *	1979-07-05	1983-05-24	Yamanouchi Pharmaceutical Co. Ltd.	Process for the production of sustained release pharmaceutical composition of solid medical material
US4259314A (en) *	1979-12-10	1981-03-31	Hans Lowey	Method and composition for the preparation of controlled long-acting pharmaceuticals
JPS5668619A (en) *	1980-10-09	1981-06-09	Yamanouchi Pharmaceut Co Ltd	Nifedipine-containing solid composition
JPS5877811A (ja) *	1981-11-04	1983-05-11	Kanebo Ltd	安定な易吸収性ニフエジピン製剤の製法
US4369172A (en) *	1981-12-18	1983-01-18	Forest Laboratories Inc.	Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose
JPS58109412A (ja) *	1981-12-23	1983-06-29	Toa Eiyou Kagaku Kogyo Kk	ニフエジピン固形製剤
US4389393A (en) *	1982-03-26	1983-06-21	Forest Laboratories, Inc.	Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose
DE3307422A1 (de) *	1983-03-03	1984-09-06	Bayer Ag, 5090 Leverkusen	Fluessigzubereitungen von dihydropyridinen, ein verfahren zu ihrer herstellung, sowie ihre verwendung bei der bekaempfung von erkrankungen

1983
- 1983-08-11 JP JP58147871A patent/JPS6038322A/ja active Granted
1984
- 1984-07-26 US US06/634,431 patent/US4654206A/en not_active Expired - Lifetime
- 1984-07-27 ZA ZA845844A patent/ZA845844B/xx unknown
- 1984-07-30 AU AU31306/84A patent/AU564506B2/en not_active Ceased
- 1984-07-31 IE IE1974/84A patent/IE57757B1/en not_active IP Right Cessation
- 1984-08-01 GR GR80004A patent/GR80004B/el unknown
- 1984-08-02 IL IL72565A patent/IL72565A/xx not_active IP Right Cessation
- 1984-08-03 AT AT0251584A patent/AT382779B/de not_active IP Right Cessation
- 1984-08-03 GB GB08419815A patent/GB2145332B/en not_active Expired
- 1984-08-03 CA CA000460336A patent/CA1228815A/en not_active Expired
- 1984-08-06 PH PH31069A patent/PH21551A/en unknown
- 1984-08-06 FI FI843083A patent/FI83839C/fi not_active IP Right Cessation
- 1984-08-09 ES ES535019A patent/ES8601686A1/es not_active Expired
- 1984-08-09 DE DE8484109470T patent/DE3484259D1/de not_active Expired - Lifetime
- 1984-08-09 CH CH3833/84A patent/CH660967A5/de not_active IP Right Cessation
- 1984-08-09 IT IT8422294A patent/IT1183062B/it active
- 1984-08-09 EP EP84109470A patent/EP0137198B1/en not_active Expired - Lifetime
- 1984-08-10 BE BE0/213487A patent/BE900348A/fr not_active IP Right Cessation
- 1984-08-10 KR KR1019840004787A patent/KR910003559B1/ko not_active IP Right Cessation
- 1984-08-10 DK DK388884A patent/DK164020C/da not_active IP Right Cessation
- 1984-08-10 FR FR8412706A patent/FR2550444B1/fr not_active Expired
1987
- 1987-09-03 SG SG730/87A patent/SG73087G/en unknown
- 1987-09-26 MY MYPI87001970A patent/MY100042A/en unknown
1988
- 1988-01-21 HK HK66/88A patent/HK6688A/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
CA1228815A (en)	1987-11-03
FI843083A (fi)	1985-02-12
EP0137198A3 (en)	1986-10-01
CH660967A5 (de)	1987-06-30
GB8419815D0 (en)	1984-09-05
SG73087G (en)	1988-03-04
DK164020C (da)	1992-09-28
GR80004B (en)	1984-11-30
IE841974L (en)	1985-02-11
EP0137198A2 (en)	1985-04-17
MY100042A (en)	1989-06-29
US4654206A (en)	1987-03-31
ZA845844B (en)	1985-05-29
FI843083A0 (fi)	1984-08-06
PH21551A (en)	1987-12-11
HK6688A (en)	1988-01-29
JPS6038322A (ja)	1985-02-27
JPH0412245B2 (xx)	1992-03-04
IT1183062B (it)	1987-10-05
IL72565A0 (en)	1984-11-30
IE57757B1 (en)	1993-03-24
DK164020B (da)	1992-05-04
ES535019A0 (es)	1985-11-01
KR850001691A (ko)	1985-04-01
FR2550444B1 (fr)	1988-09-16
EP0137198B1 (en)	1991-03-13
DE3484259D1 (de)	1991-04-18
AU564506B2 (en)	1987-08-13
FI83839C (fi)	1991-09-10
AU3130684A (en)	1985-02-14
GB2145332B (en)	1987-03-25
ATA251584A (de)	1986-09-15
IT8422294A0 (it)	1984-08-09
ES8601686A1 (es)	1985-11-01
GB2145332A (en)	1985-03-27
FR2550444A1 (fr)	1985-02-15
DK388884A (da)	1985-02-12
DK388884D0 (da)	1984-08-10
FI83839B (fi)	1991-05-31
AT382779B (de)	1987-04-10
BE900348A (fr)	1985-02-11
KR910003559B1 (ko)	1991-06-05

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Legal Events

Date	Code	Title	Description
1998-12-27	KB	Patent renewed
2003-05-29	MM9K	Patent not in force due to non-payment of renewal fees