IL67577A - Penta-and hexapeptides having growth hormone releasing activity,their preparation and pharmaceutical compositions containing them - Google Patents
Penta-and hexapeptides having growth hormone releasing activity,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL67577A IL67577A IL67577A IL6757782A IL67577A IL 67577 A IL67577 A IL 67577A IL 67577 A IL67577 A IL 67577A IL 6757782 A IL6757782 A IL 6757782A IL 67577 A IL67577 A IL 67577A
- Authority
- IL
- Israel
- Prior art keywords
- hexapeptides
- penta
- preparation
- pharmaceutical compositions
- compositions containing
- Prior art date
Links
- 102000018997 Growth Hormone Human genes 0.000 title 1
- 108010051696 Growth Hormone Proteins 0.000 title 1
- 239000000122 growth hormone Substances 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 230000003578 releasing effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/60—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Endocrinology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Obesity (AREA)
- Molecular Biology (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL82215A IL82215A (en) | 1981-12-28 | 1982-12-28 | Peptide-resin and protected peptide compounds and their preparation |
IL82215A IL82215A0 (en) | 1981-12-28 | 1987-04-16 | Peptide-resin and protected peptide compounds and their preparation |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/335,000 US4410513A (en) | 1981-12-28 | 1981-12-28 | Synthetic peptides having pituitary growth hormone releasing activity |
US06/334,488 US4410512A (en) | 1981-12-28 | 1981-12-28 | Combinations having synergistic pituitary growth hormone releasing activity |
US06/335,011 US4411890A (en) | 1981-04-14 | 1981-12-28 | Synthetic peptides having pituitary growth hormone releasing activity |
Publications (1)
Publication Number | Publication Date |
---|---|
IL67577A true IL67577A (en) | 1988-07-31 |
Family
ID=27406978
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL67577A IL67577A (en) | 1981-12-28 | 1982-12-28 | Penta-and hexapeptides having growth hormone releasing activity,their preparation and pharmaceutical compositions containing them |
IL82215A IL82215A (en) | 1981-12-28 | 1982-12-28 | Peptide-resin and protected peptide compounds and their preparation |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL82215A IL82215A (en) | 1981-12-28 | 1982-12-28 | Peptide-resin and protected peptide compounds and their preparation |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP0083864B1 (fi) |
JP (1) | JPS58501861A (fi) |
KR (2) | KR890002760B1 (fi) |
AU (1) | AU549053B2 (fi) |
BR (1) | BR8208035A (fi) |
CA (2) | CA1242435A (fi) |
DE (1) | DE3276319D1 (fi) |
DK (2) | DK390883A (fi) |
DO (1) | DOP1982004152A (fi) |
FI (1) | FI77251C (fi) |
IE (1) | IE54515B1 (fi) |
IL (2) | IL67577A (fi) |
PT (1) | PT76041B (fi) |
WO (1) | WO1983002272A1 (fi) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4839344A (en) * | 1987-06-12 | 1989-06-13 | Eastman Kodak Company | Polypeptide compounds having growth hormone releasing activity |
AU618029B2 (en) * | 1987-11-02 | 1991-12-12 | Imperial Chemical Industries Plc | Polypeptide compounds |
JPH03502326A (ja) * | 1988-01-28 | 1991-05-30 | ポリゲン ホールディング コーポレイション | 成長ホルモン放出活性を有するポリペプチド化合物類 |
EP0400051B1 (en) * | 1988-01-28 | 1995-05-10 | Polygen Holding Corporation | Polypeptide compounds having growth hormone releasing activity |
DE68912775T2 (de) * | 1988-05-11 | 1994-06-30 | Polygen Holding Corp | Polypeptid-verbindungen mit hormonwachstumsbefreiender wirkung. |
GB8813356D0 (en) * | 1988-06-06 | 1988-07-13 | Ici Plc | Polypeptide compounds |
EP0448513A3 (en) * | 1990-03-21 | 1991-12-27 | Japat Ltd | Process for production of peptidylglycine alpha-hydroxylating monooxygenase and use thereof |
US5668254A (en) * | 1990-05-11 | 1997-09-16 | Romano Deghenghi | D-2-alkyl-tryptophan and peptides containing same |
IT1240643B (it) * | 1990-05-11 | 1993-12-17 | Mediolanum Farmaceutici Spa | Peptidi biologicamente attivi contenenti in catena 2-alchiltriptofano |
US5872100A (en) * | 1990-05-11 | 1999-02-16 | Deghenghi; Romano | Peptides containing D-2-Alkyl-Tryptophan |
US5492894A (en) * | 1991-03-21 | 1996-02-20 | The Procter & Gamble Company | Compositions for treating wrinkles comprising a peptide |
US5663146A (en) * | 1991-08-22 | 1997-09-02 | Administrators Of The Tulane Educational Fund | Polypeptide analogues having growth hormone releasing activity |
PL181280B1 (pl) * | 1993-12-23 | 2001-07-31 | Novo Nordisk As | oraz zawierajaca je kompozycja farmaceutyczna PL PL PL PL PL PL PL PL |
CA2201122A1 (en) * | 1994-09-27 | 1996-04-04 | Romano Deghenghi | Polypeptide compounds containing d-2-alkyltryptophan capable of promoting the release of growth hormone |
EP1005484A1 (en) | 1997-06-20 | 2000-06-07 | Novo Nordisk A/S | Compounds with growth hormone releasing properties |
JP4382279B2 (ja) | 1998-01-16 | 2009-12-09 | サファイア セラピューティクス,インコーポレイティド | 成長ホルモン放出特性を有する化合物 |
US6919315B1 (en) | 1998-06-30 | 2005-07-19 | Novo Nordisk A/S | Compounds with growth hormone releasing properties |
US6468974B1 (en) | 1998-08-14 | 2002-10-22 | The Administrators Of The Tulane Educational Fund | Compounds having growth hormone releasing activity |
US9119832B2 (en) | 2014-02-05 | 2015-09-01 | The Regents Of The University Of California | Methods of treating mild brain injury |
US20170121385A1 (en) | 2015-10-28 | 2017-05-04 | Oxeia Biopharmaceuticals, Inc. | Methods of treating neurodegenerative conditions |
CN106216464B (zh) * | 2016-09-27 | 2017-12-12 | 天津职业技术师范大学 | 中空薄壁管件旋拧设备及其运行方法 |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2871225A (en) * | 1954-06-03 | 1959-01-27 | Rohm & Haas | Method for preparing polypeptides |
US3093627A (en) * | 1958-07-03 | 1963-06-11 | Ciba Geigy Corp | Polypeptides and process for their manufacture |
US3664925A (en) * | 1970-02-20 | 1972-05-23 | Martin Sonenberg | Clinically active bovine growth hormone fraction |
DE2158123A1 (de) * | 1970-12-02 | 1972-06-08 | Ciba-Geigy Ag, Basel (Schweiz) | Neue pharmazeutische Präparate |
US3862925A (en) * | 1973-07-05 | 1975-01-28 | American Home Prod | Preparation of somatotropin release inhibiting factor and intermediates therefor |
JPS5726506B2 (fi) * | 1974-03-08 | 1982-06-04 | ||
HU184704B (en) * | 1976-01-26 | 1984-10-29 | Wellcome Found | Process for preparing biologically active encephaline analogues |
DE2862327D1 (en) * | 1977-07-22 | 1983-11-10 | Wellcome Found | Pentapeptide-n-alkylamides and their acid addition salts, methods for preparation of these compounds and pharmaceutical formulations containing them |
US4228155A (en) * | 1979-03-30 | 1980-10-14 | Beckman Instruments, Inc. | Synthetic peptides having pituitary growth hormone releasing activity |
US4228157A (en) * | 1979-03-30 | 1980-10-14 | Beckman Instruments, Inc. | Synthetic peptides having pituitary growth hormone releasing activity |
US4228156A (en) * | 1979-03-30 | 1980-10-14 | Beckman Instruments, Inc. | Synthetic peptides having pituitary growth hormone releasing activity |
CA1175810A (en) * | 1979-03-30 | 1984-10-09 | Frank A. Momany | Synthetic peptides having pituitary growth hormone releasing activity |
US4228158A (en) * | 1979-03-30 | 1980-10-14 | Beckman Instruments, Inc. | Synthetic peptides having pituitary growth hormone releasing activity |
US4223021A (en) * | 1979-03-30 | 1980-09-16 | Beckman Instruments, Inc. | Synthetic peptides having pituitary growth hormone releasing activity |
US4224316A (en) * | 1979-03-30 | 1980-09-23 | Beckman Instruments, Inc. | Synthetic peptides having pituitary growth hormone releasing activity |
US4223019A (en) * | 1979-03-30 | 1980-09-16 | Beckman Instruments, Inc. | Synthetic peptides having pituitary growth hormone releasing activity |
US4226857A (en) * | 1979-03-30 | 1980-10-07 | Beckman Instruments, Inc. | Synthetic peptides having pituitary growth hormone releasing activity |
US4223020A (en) * | 1979-03-30 | 1980-09-16 | Beckman Instruments, Inc. | Synthetic peptides having pituitary growth hormone releasing activity |
US4251439A (en) * | 1979-12-17 | 1981-02-17 | Eli Lilly And Company | Pharmacologically active peptides |
-
1982
- 1982-12-20 JP JP83500559A patent/JPS58501861A/ja active Pending
- 1982-12-20 WO PCT/US1982/001787 patent/WO1983002272A1/en active IP Right Grant
- 1982-12-20 AU AU11547/83A patent/AU549053B2/en not_active Expired
- 1982-12-20 BR BR8208035A patent/BR8208035A/pt unknown
- 1982-12-22 EP EP82306862A patent/EP0083864B1/en not_active Expired
- 1982-12-22 DE DE8282306862T patent/DE3276319D1/de not_active Expired
- 1982-12-23 IE IE3072/82A patent/IE54515B1/en not_active IP Right Cessation
- 1982-12-23 CA CA000418537A patent/CA1242435A/en not_active Expired
- 1982-12-23 DO DO1982004152A patent/DOP1982004152A/es unknown
- 1982-12-28 PT PT76041A patent/PT76041B/pt unknown
- 1982-12-28 IL IL67577A patent/IL67577A/xx not_active IP Right Cessation
- 1982-12-28 KR KR8205836A patent/KR890002760B1/ko active
- 1982-12-28 IL IL82215A patent/IL82215A/xx not_active IP Right Cessation
-
1983
- 1983-08-26 DK DK390883A patent/DK390883A/da not_active Application Discontinuation
- 1983-08-26 FI FI833057A patent/FI77251C/fi not_active IP Right Cessation
-
1988
- 1988-02-25 CA CA000559803A patent/CA1317069C/en not_active Expired - Lifetime
-
1989
- 1989-06-02 KR KR1019890007576A patent/KR900002681B1/ko not_active IP Right Cessation
-
1992
- 1992-09-16 DK DK921141A patent/DK114192D0/da unknown
Also Published As
Publication number | Publication date |
---|---|
FI833057A (fi) | 1983-08-26 |
WO1983002272A1 (en) | 1983-07-07 |
EP0083864A2 (en) | 1983-07-20 |
CA1317069C (en) | 1993-04-27 |
IL82215A (en) | 1988-07-31 |
FI833057A0 (fi) | 1983-08-26 |
KR890002760B1 (ko) | 1989-07-27 |
KR900002681B1 (ko) | 1990-04-23 |
EP0083864A3 (en) | 1983-09-14 |
DE3276319D1 (en) | 1987-06-19 |
IE823072L (en) | 1983-06-28 |
KR840002772A (ko) | 1984-07-16 |
EP0083864B1 (en) | 1987-05-13 |
AU549053B2 (en) | 1986-01-09 |
JPS58501861A (ja) | 1983-11-04 |
CA1242435A (en) | 1988-09-27 |
PT76041B (en) | 1985-07-26 |
IE54515B1 (en) | 1989-11-08 |
BR8208035A (pt) | 1983-11-22 |
DK390883D0 (da) | 1983-08-26 |
DOP1982004152A (es) | 1988-09-01 |
DK114192A (da) | 1992-09-16 |
PT76041A (en) | 1983-01-01 |
DK114192D0 (da) | 1992-09-16 |
FI77251C (fi) | 1989-02-10 |
FI77251B (fi) | 1988-10-31 |
DK390883A (da) | 1983-08-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
KB | Patent renewed | ||
KB | Patent renewed | ||
EXP | Patent expired |