IL63038A0 - Vinblastine derivatives - Google Patents

Vinblastine derivatives

Info

Publication number: IL63038A0
Authority: IL; Israel
Prior art keywords: derivatives; vinblastine; vinblastine derivatives; amino acid; preparation
Prior art date: 1980-06-10

Application number

IL63038A

Other languages

English (en)

Original Assignee

Omnichem Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1980-06-10

Filing date

1981-06-04

Publication date

1981-09-13

1980-06-10 Priority claimed from LU82514A external-priority patent/LU82514A1/fr

1980-12-23 Priority claimed from LU83034A external-priority patent/LU83034A1/fr

1981-06-04 Application filed by Omnichem Sa filed Critical Omnichem Sa

1981-09-13 Publication of IL63038A0 publication Critical patent/IL63038A0/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
- C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Steroid Compounds (AREA)
Distillation Of Fermentation Liquor, Processing Of Alcohols, Vinegar And Beer (AREA)
Medicinal Preparation (AREA)

IL63038A 1980-06-10 1981-06-04 Vinblastine derivatives IL63038A0 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
LU82514A LU82514A1 (fr)	1980-06-10	1980-06-10	Derives n-(vinblastinoyl-23)d'acides amines,leur preparation et leur application therapeutique
LU83034A LU83034A1 (fr)	1980-12-23	1980-12-23	Derives n-(vinblastinoyl-23) d'acides amines et de peptides, leur preparation et leur application therapeutique

Publications (1)

Publication Number	Publication Date
IL63038A0 true IL63038A0 (en)	1981-09-13

Family

ID=26640267

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL63038A IL63038A0 (en)	1980-06-10	1981-06-04	Vinblastine derivatives

Country Status (21)

Country	Link
US (1)	US4388305A (xx)
EP (1)	EP0041935B1 (xx)
AT (2)	AT390793B (xx)
AU (1)	AU541747B2 (xx)
CA (1)	CA1196326A (xx)
DD (1)	DD160417A5 (xx)
DE (2)	DE3122479A1 (xx)
DK (1)	DK160614C (xx)
ES (1)	ES8203385A1 (xx)
FR (1)	FR2483926A1 (xx)
GB (1)	GB2078730A (xx)
GR (1)	GR74565B (xx)
HU (1)	HU185261B (xx)
IE (1)	IE51403B1 (xx)
IL (1)	IL63038A0 (xx)
IT (1)	IT1144601B (xx)
NL (1)	NL8102802A (xx)
NZ (1)	NZ197299A (xx)
OA (1)	OA06421A (xx)
PT (1)	PT73161B (xx)
SE (1)	SE8103594L (xx)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4639456A (en) *	1980-06-10	1987-01-27	Omnichem S.A.	Vinblastin-23-oyl amino acid derivatives
LU83822A1 (fr) *	1981-12-08	1983-09-01	Omnichem Sa	Derives n-(vinblastinoyl-23)d'acides amines,leur preparation et leur application therapeutique
IT1170152B (it) *	1982-07-19	1987-06-03	Lilly Co Eli	Miglioramenti a o riguardanti formulazioni di vinca-alcaloidi
DE3483336D1 (de) *	1983-03-30	1990-11-08	Lilly Industries Ltd	Vincaleukoblastin-derivate.
GR81790B (xx) *	1983-04-29	1984-12-12	Omnichem Sa
US4667030A (en) *	1985-06-17	1987-05-19	Eli Lilly And Company	Hydrazide succinimide derivatives of antineoplastic indole-dihydroindole alkaloids
US4675400A (en) *	1985-06-17	1987-06-23	Eli Lilly And Company	Bifunctional derivatives of 4-desacetyl indole-dihydroindole alkaloids
FI860456A (fi) *	1985-07-16	1987-01-17	Huhtamaeki Oy Laeaeketehdas Le	Bis-indolalkaloiders proteinkonjugat, bis-indolalkaloider, deras framstaellning och anvaendning.
EP0232693A3 (fr) *	1985-12-16	1988-04-06	La Region Wallonne	Conjugués de la vinblastine et de ses dérivés, procédé pour leur préparation et compositions pharmaceutiques les contenant
EP0233101A1 (fr) *	1986-01-13	1987-08-19	Ire-Celltarg S.A.	Dérivés de vinblastine et composition pharmaceutique les contenant
ES2045092T3 (es) *	1987-11-11	1994-01-16	Akzo Nv	Un procedimiento de manufactura de un producto farmaceutico para tratamiento de cancer.
FR2623504B1 (fr) *	1987-11-25	1990-03-09	Adir	Nouveaux derives n-(vinblastinoyl-23) d'acide amino-1 methylphosphonique, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
FR2626882B1 (fr) *	1988-02-08	1991-11-08	Ire Celltarg Sa	Conjugues de derives de vinca comportant une chaine detergente en position c-3
US4980343A (en) *	1988-10-27	1990-12-25	Bayer Aktiengesellschaft	Aminooxodihydroisoindoloquinazoline carcinostatic agents
US5043336A (en) *	1990-04-03	1991-08-27	Eli Lilly And Company	Cyclic imide derivatives of 4-desacetyl VLB c-3 carboxhydrazide
US5043340A (en) *	1990-04-03	1991-08-27	Eli Lilly And Company	Derivatives of 4-desacetyl VLB C-3 carboxhydrazide
US5866679A (en) *	1994-06-28	1999-02-02	Merck & Co., Inc.	Peptides
US5599686A (en) *	1994-06-28	1997-02-04	Merck & Co., Inc.	Peptides
US6143864A (en) *	1994-06-28	2000-11-07	Merck & Co., Inc.	Peptides
WO1996005863A1 (fr) *	1994-08-19	1996-02-29	La Region Wallonne	Composes, composition pharmaceutique et dispositif de diagnostic les comprenant et leur utilisation
BE1008581A3 (fr) *	1994-08-19	1996-06-04	Wallone Region	Prodrogues, composition pharmaceutique les comprenant et leur utilisation.
US5998362A (en) *	1996-09-12	1999-12-07	Merck & Co., Inc.	Conjugates useful in the treatment of prostate cancer
US5948750A (en) *	1996-10-30	1999-09-07	Merck & Co., Inc.	Conjugates useful in the treatment of prostate cancer
US6127333A (en) *	1997-07-10	2000-10-03	Merck & Co., Inc.	Conjugates useful in the treatment of prostate cancer
US6391305B1 (en)	1997-09-10	2002-05-21	Merck & Co., Inc.	Conjugates useful in the treatment of prostate cancer
AU5240999A (en) *	1998-07-31	2000-02-21	Goldsmith Seeds Inc.	Trimeric and polymeric alkaloids
DE19842416A1 (de) *	1998-09-16	2000-04-13	Max Planck Gesellschaft	Sekundäre Amine zur Prävention und Therapie von Erkrankungen, die durch Oxidationsprozesse verursacht oder verstärkt werden
US7425541B2 (en)	1998-12-11	2008-09-16	Medarex, Inc.	Enzyme-cleavable prodrug compounds
CA2413149A1 (en)	2000-06-14	2001-12-20	Medarex, Inc.	Prodrug compounds with isoleucine
US20030232760A1 (en) *	2001-09-21	2003-12-18	Merck & Co., Inc.	Conjugates useful in the treatment of prostate cancer
WO2005055943A2 (en) *	2003-12-04	2005-06-23	Amr Technology, Inc.	Vinorelbine derivatives
NZ547370A (en) *	2003-12-04	2010-09-30	Amr Technology Inc	Vinca derivatives
US20080125451A1 (en) *	2006-09-12	2008-05-29	Amr Technology, Inc.	Vinorelbine derivatives
US8039453B2 (en) *	2006-09-12	2011-10-18	Albany Molecular Research, Inc.	Vinca derivatives
KR20230038457A (ko)	2020-06-10	2023-03-20	알리고스 테라퓨틱스 인코포레이티드	코로나바이러스, 피코르나바이러스 및 노로바이러스 감염을 치료하기 위한 항바이러스 화합물
KR20240035513A (ko)	2021-07-09	2024-03-15	알리고스 테라퓨틱스 인코포레이티드	항바이러스 화합물
WO2023043816A1 (en)	2021-09-17	2023-03-23	Aligos Therapeutics, Inc.	Anti-viral compounds for treating coronavirus, picornavirus, and norovirus infections

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3387001A (en) *	1964-10-19	1968-06-04	Lilly Co Eli	Novel aminoacyl esters of desacetyl vincaleukoblastine
AR204004A1 (es) *	1973-04-02	1975-11-12	Lilly Co Eli	Procedimientos para preparar derivados de vinblastina leurosidina y leurocristina
GR69783B (xx) *	1976-09-08	1982-07-07	Lilly Co Eli
US4203898A (en) *	1977-08-29	1980-05-20	Eli Lilly And Company	Amide derivatives of VLB, leurosidine, leurocristine and related dimeric alkaloids

1979
- 1979-12-13 OA OA56972A patent/OA06421A/xx unknown
1981
- 1981-05-30 ES ES502644A patent/ES8203385A1/es not_active Expired
- 1981-06-02 GR GR65133A patent/GR74565B/el unknown
- 1981-06-02 AU AU71262/81A patent/AU541747B2/en not_active Ceased
- 1981-06-03 US US06/269,876 patent/US4388305A/en not_active Expired - Fee Related
- 1981-06-03 NZ NZ197299A patent/NZ197299A/en unknown
- 1981-06-04 IL IL63038A patent/IL63038A0/xx not_active IP Right Cessation
- 1981-06-04 CA CA000379041A patent/CA1196326A/en not_active Expired
- 1981-06-04 IE IE1275/81A patent/IE51403B1/en not_active IP Right Cessation
- 1981-06-05 DE DE19813122479 patent/DE3122479A1/de not_active Withdrawn
- 1981-06-05 AT AT0253881A patent/AT390793B/de not_active IP Right Cessation
- 1981-06-08 IT IT67782/81A patent/IT1144601B/it active
- 1981-06-08 GB GB8117454A patent/GB2078730A/en not_active Withdrawn
- 1981-06-09 SE SE8103594A patent/SE8103594L/xx not_active Application Discontinuation
- 1981-06-09 FR FR8111330A patent/FR2483926A1/fr active Granted
- 1981-06-09 DD DD81230660A patent/DD160417A5/de not_active IP Right Cessation
- 1981-06-09 DE DE8181870028T patent/DE3166150D1/de not_active Expired
- 1981-06-09 PT PT73161A patent/PT73161B/pt unknown
- 1981-06-09 AT AT81870028T patent/ATE9475T1/de active
- 1981-06-09 EP EP81870028A patent/EP0041935B1/fr not_active Expired
- 1981-06-09 DK DK250181A patent/DK160614C/da not_active IP Right Cessation
- 1981-06-10 NL NL8102802A patent/NL8102802A/nl not_active Application Discontinuation
- 1981-06-10 HU HU811725A patent/HU185261B/hu not_active IP Right Cessation

Also Published As

Publication number	Publication date
NZ197299A (en)	1985-10-11
ES502644A0 (es)	1982-04-01
CA1196326A (en)	1985-11-05
DK250181A (da)	1981-12-11
IT1144601B (it)	1986-10-29
ES8203385A1 (es)	1982-04-01
ATE9475T1 (de)	1984-10-15
NL8102802A (nl)	1982-01-04
FR2483926B1 (xx)	1983-07-29
AT390793B (de)	1990-06-25
GB2078730A (en)	1982-01-13
US4388305A (en)	1983-06-14
IT8167782A0 (it)	1981-06-08
EP0041935A1 (fr)	1981-12-16
EP0041935B1 (fr)	1984-09-19
AU7126281A (en)	1981-12-17
DD160417A5 (de)	1983-07-27
FR2483926A1 (fr)	1981-12-11
PT73161B (fr)	1982-07-16
PT73161A (fr)	1981-07-01
GR74565B (xx)	1984-06-29
DK160614C (da)	1991-09-23
SE8103594L (sv)	1981-12-11
HU185261B (en)	1984-12-28
ATA253881A (de)	1989-12-15
AU541747B2 (en)	1985-01-17
OA06421A (fr)	1981-09-30
DE3122479A1 (de)	1982-06-16
DE3166150D1 (en)	1984-10-25
IE811275L (en)	1981-12-10
DK160614B (da)	1991-04-02
IE51403B1 (en)	1986-12-24

Publication	Publication Date	Title
FR2483926B1 (xx)	1983-07-29
DE3366494D1 (de)	1986-11-06	New 6-substituted-s-triazolo(3,4-a)phthalazine derivatives
DE3370482D1 (en)	1987-04-30	Substituted 8-phenylxanthines
EP0046953A3 (en)	1982-05-05	Amino acid derivatives, processes for their preparation, compositions containing them and their use
IL60510A (en)	1986-11-30	Derivatives of n-(mercaptoalkylcarbonyl)glycine,processes for their preparation and pharmaceutical compositions containing them
GR80840B (en)	1985-02-26	Novel polypeptide with a - amylase inhibiting effect, method for the preparation thereof, use and pharmaceutical preparations thereof
DE3166084D1 (en)	1984-10-18	Tricyclic cytosine derivatives for use in pharmaceutical preparations and process for their preparation
JO1406B1 (en)	1986-11-30	Chemical compounds
DK161384C (da)	1992-01-06	Pyrazolooe3,4,5-klaaacridinforbindelser og farmaceutiske praeparater indeholdende saadanne forbindelser
AU539847B2 (en)	1984-10-18	3,4,5-trihydroxypiperidine compounds
ES480091A1 (es)	1980-04-01	Metodo de producir (omega-aminoalcoxi) bibencilos farmaceu- ticamente activos.
AR244241A1 (es)	1993-10-29	Procedimiento para preparar derivados de acido n-(aminoalcanoil)-azabiciclocarboxilico
IL69274A (en)	1986-08-31	(substituted amino)derivatives of 3-benzylidene-pyrrolo(2,1-b)quinazolin-9-ones and 6-benzylidene-pyrido(2,1-b)quinazolin-11-ones,their preparation and pharmaceutical compositions containing them
ES8705847A1 (es)	1987-05-16	Procedimiento para preparar nuevos derivados de n-(2-hidro- xialquil)-aminoacidos

Legal Events

Date	Code	Title	Description
1996-03-31	RH	Patent void