IL52181A - Kanamycin and tobramycin derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

Kanamycin and tobramycin derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number: IL52181A
Authority: IL; Israel
Prior art keywords: tobramycin; kanamycin; derivatives; preparation; pharmaceutical compositions
Prior art date: 1976-06-16

Application number

IL52181A

Other languages

English (en)

Other versions

IL52181A0 (en

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-06-16

Filing date

1977-05-27

Publication date

1981-03-31

1976-06-16 Priority claimed from GB24989/76A external-priority patent/GB1530202A/en

1977-05-27 Application filed by Pfizer filed Critical Pfizer

1977-07-31 Publication of IL52181A0 publication Critical patent/IL52181A0/xx

1981-03-31 Publication of IL52181A publication Critical patent/IL52181A/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
- C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
- C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
- C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biotechnology (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Oncology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Communicable Diseases (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Saccharide Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

IL52181A 1976-06-16 1977-05-27 Kanamycin and tobramycin derivatives,their preparation and pharmaceutical compositions containing them IL52181A (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GB24989/76A GB1530202A (en)	1976-06-16	1976-06-16	Aminoglycosides
GB4014576		1976-09-28
GB5129476		1976-12-08

Publications (2)

Publication Number	Publication Date
IL52181A0 IL52181A0 (en)	1977-07-31
IL52181A true IL52181A (en)	1981-03-31

Family

ID=27258386

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL52181A IL52181A (en)	1976-06-16	1977-05-27	Kanamycin and tobramycin derivatives,their preparation and pharmaceutical compositions containing them

Country Status (31)

Country	Link
US (1)	US4214074A (no)
JP (1)	JPS52153943A (no)
AR (1)	AR222781A1 (no)
AT (1)	AT350722B (no)
BG (1)	BG28071A3 (no)
CA (1)	CA1075235A (no)
CH (1)	CH606079A5 (no)
CS (1)	CS203157B2 (no)
DD (1)	DD131019A5 (no)
DE (1)	DE2726839C3 (no)
DK (1)	DK147942C (no)
EG (1)	EG12742A (no)
ES (1)	ES459832A1 (no)
FI (1)	FI771873A (no)
FR (1)	FR2355029A1 (no)
GR (1)	GR66411B (no)
HU (1)	HU179054B (no)
IE (1)	IE45389B1 (no)
IL (1)	IL52181A (no)
LU (1)	LU77557A1 (no)
MX (1)	MX4323E (no)
NL (1)	NL170736C (no)
NO (1)	NO144851C (no)
NZ (1)	NZ184213A (no)
PH (1)	PH14663A (no)
PL (1)	PL108094B1 (no)
PT (1)	PT66669B (no)
RO (1)	RO73516A (no)
SE (1)	SE7706944L (no)
SU (1)	SU865128A3 (no)
YU (1)	YU132577A (no)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK308878A (da) *	1977-08-18	1979-02-19	Pfizer	Aminoglyosidderivater og fremgangsmaader til deres fremstilling
DE2832268A1 (de) *	1978-07-22	1980-01-31	Bayer Ag	Pseudotrisaccharide
DE2928183A1 (de) *	1979-07-12	1981-01-29	Bayer Ag	1-n-alkylsisomicin-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
JPS5931266A (ja) *	1982-08-11	1984-02-20	株式会社日立製作所	エレベ−タ−の制御装置
KR100450607B1 (ko) *	2002-07-11	2004-09-30	경동제약 주식회사	가라민 유도체의 제조방법
US7794713B2 (en)	2004-04-07	2010-09-14	Lpath, Inc.	Compositions and methods for the treatment and prevention of hyperproliferative diseases
US7862812B2 (en)	2006-05-31	2011-01-04	Lpath, Inc.	Methods for decreasing immune response and treating immune conditions
MX2010005632A (es)	2007-11-21	2010-09-10	Achaogen Inc	Analogos de aminoglucosidos antibacterianos.
CA2761756A1 (en) *	2009-05-14	2010-11-18	Achaogen, Inc.	Treatment of urinary tract infections with antibacterial aminoglycoside compounds
WO2010132760A1 (en)	2009-05-15	2010-11-18	Achaogen, Inc.	Antibacterial derivatives of tobramycin
WO2010132759A1 (en)	2009-05-15	2010-11-18	Achaogen, Inc.	Antibacterial derivatives of dibekacin
WO2010132768A1 (en)	2009-05-15	2010-11-18	Achaogen, Inc.	Antibacterial derivatives of sisomicin
WO2010132757A2 (en)	2009-05-15	2010-11-18	Achaogen, Inc.	Antibacterial aminoglycoside analogs
WO2010132765A2 (en)	2009-05-15	2010-11-18	Achaogen, Inc.	Antibacterial aminoglycoside analogs

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1033394A (en) *	1962-04-03	1966-06-22	Rit Rech Ind Therapeut	New therapeutic agents
US4002742A (en) *	1974-03-19	1977-01-11	Schering Corporation	1-N-alkyl-4,6-di-(aminoglycosyl)-1,3-diaminocyclitols, methods for their manufacture, methods for their use as antibacterial agents, and compositions useful therefor
US4000261A (en) *	1974-11-29	1976-12-28	Schering Corporation	5-epi-4,6-di-o-(aminoglycosyl)-2-deoxystreptamines, methods for their manufacture and intermediates useful therein, methods for their use as antibacterial agents and compositions useful therefor
US4000262A (en) *	1974-11-29	1976-12-28	Schering Corporation	5-epi-amino and 5-epi-azido-4,6-di-o-(aminoglycosyl)-2,5-dideoxystreptamines 1-n-alkyl-5-epi-amino and 1-n-alkyl-5-epi-azido-4,6-di-o-(aminoglycosyl)-2,5-dideoxystreptamines
US4062947A (en) *	1975-11-04	1977-12-13	Schering Corporation	Di-N-alkylaminoglycosides, methods for their manufacture and novel intermediates useful therein, method for their use as antibacterial agents and pharmaceutical compositions useful therefor
US4085208A (en) *	1976-06-21	1978-04-18	Schering Corporation	Process for preparing 4,6-di-O-(aminoglycosyl)-1,3-diaminocyclitols and novel 1-epimers and 1-N-alkyl derivatives produced thereby; methods for the use of the 1-epimer derivatives as antibacterial agents and compositions useful therefor

1977
- 1977-05-26 NZ NZ184213A patent/NZ184213A/xx unknown
- 1977-05-27 IL IL52181A patent/IL52181A/xx unknown
- 1977-05-27 YU YU01325/77A patent/YU132577A/xx unknown
- 1977-05-30 EG EG329/77A patent/EG12742A/xx active
- 1977-05-31 PH PH19833A patent/PH14663A/en unknown
- 1977-06-02 MX MX775775U patent/MX4323E/es unknown
- 1977-06-03 AR AR267934A patent/AR222781A1/es active
- 1977-06-03 CA CA279,773A patent/CA1075235A/en not_active Expired
- 1977-06-08 CS CS773790A patent/CS203157B2/cs unknown
- 1977-06-13 BG BG036611A patent/BG28071A3/xx unknown
- 1977-06-13 AT AT414277A patent/AT350722B/de not_active IP Right Cessation
- 1977-06-14 PT PT66669A patent/PT66669B/pt unknown
- 1977-06-14 FI FI771873A patent/FI771873A/fi not_active Application Discontinuation
- 1977-06-14 NL NLAANVRAGE7706514,A patent/NL170736C/xx not_active IP Right Cessation
- 1977-06-14 GR GR53699A patent/GR66411B/el unknown
- 1977-06-14 DE DE2726839A patent/DE2726839C3/de not_active Expired
- 1977-06-14 NO NO772089A patent/NO144851C/no unknown
- 1977-06-15 FR FR7718367A patent/FR2355029A1/fr active Granted
- 1977-06-15 SU SU772494017A patent/SU865128A3/ru active
- 1977-06-15 DK DK265577A patent/DK147942C/da not_active IP Right Cessation
- 1977-06-15 HU HU77PI580A patent/HU179054B/hu unknown
- 1977-06-15 SE SE7706944A patent/SE7706944L/xx not_active Application Discontinuation
- 1977-06-15 RO RO7790693A patent/RO73516A/ro unknown
- 1977-06-15 CH CH737577A patent/CH606079A5/xx not_active IP Right Cessation
- 1977-06-15 PL PL1977198872A patent/PL108094B1/pl not_active IP Right Cessation
- 1977-06-15 JP JP7094477A patent/JPS52153943A/ja active Granted
- 1977-06-15 DD DD7700199503A patent/DD131019A5/xx unknown
- 1977-06-15 IE IE1222/77A patent/IE45389B1/en unknown
- 1977-06-16 LU LU77557A patent/LU77557A1/xx unknown
- 1977-06-16 ES ES459832A patent/ES459832A1/es not_active Expired
1978
- 1978-11-07 US US05/958,409 patent/US4214074A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
AT350722B (de)	1979-06-11
DE2726839C3 (de)	1980-05-14
CS203157B2 (en)	1981-02-27
EG12742A (en)	1979-12-31
DE2726839A1 (de)	1978-03-09
GR66411B (no)	1981-03-20
DK147942B (da)	1985-01-14
DD131019A5 (de)	1978-05-24
LU77557A1 (fr)	1979-03-26
SU865128A3 (ru)	1981-09-15
CA1075235A (en)	1980-04-08
IE45389L (en)	1977-12-16
NO772089L (no)	1977-12-19
DK265577A (da)	1977-12-17
YU132577A (en)	1982-06-30
JPS5713556B2 (no)	1982-03-17
IL52181A0 (en)	1977-07-31
DK147942C (da)	1985-09-02
PL108094B1 (pl)	1980-03-31
US4214074A (en)	1980-07-22
IE45389B1 (en)	1982-08-11
NL7706514A (nl)	1977-12-20
SE7706944L (sv)	1977-12-17
PL198872A1 (pl)	1978-03-13
DE2726839B2 (de)	1979-08-30
JPS52153943A (en)	1977-12-21
RO73516A (ro)	1981-08-30
FR2355029A1 (fr)	1978-01-13
CH606079A5 (no)	1978-10-13
NO144851C (no)	1981-11-25
MX4323E (es)	1982-03-24
NO144851B (no)	1981-08-17
FI771873A (no)	1977-12-17
AU2551177A (en)	1978-04-13
ES459832A1 (es)	1978-12-16
PT66669A (en)	1977-07-01
PT66669B (en)	1978-11-13
AR222781A1 (es)	1981-06-30
BG28071A3 (en)	1980-02-25
NZ184213A (en)	1980-05-27
HU179054B (en)	1982-08-28
FR2355029B1 (no)	1980-04-18
ATA414277A (de)	1978-11-15
NL170736C (nl)	1982-12-16
PH14663A (en)	1981-10-20

Similar Documents

Publication	Publication Date	Title
IL59288A (en)	1984-06-29	1-aryl-2-acylamido-3-fluoro-1-propanols,their preparation and pharmaceutical compositions containing them
IL60129A0 (en)	1980-07-31	Phenylsulphonamide derivatives,their preparation and pharmaceutical compositions containing them
IL51816A (en)	1981-09-13	Steroids,their preparation and pharmaceutical compositions containing them
IL57708A0 (en)	1979-11-30	Aminopropoxyindole derivatives,their preparation and pharmaceutical compositions containing them
IL53043A (en)	1982-01-31	N-heterocyclylalkyl-(1-aryloxy-2-hydroxy-3-amino-propane)derivatives,their preparation and pharmaceutical compositions containing them
IL59150A (en)	1983-11-30	N-benzyl-imidazoles,their preparation and pharmaceutical compositions containing them
DE3068678D1 (en)	1984-08-30	3-aminopropoxyaryl derivatives, their preparation and pharmaceutical compositions containing them
IL60678A0 (en)	1980-09-16	3-amino-syndone-imines, their preparation and pharmaceutical compositions containing them
IL61481A0 (en)	1980-12-31	Piperidylbenzimidazolinone derivatives,their preparation and pharmaceutical compositions containing them
IL52181A (en)	1981-03-31	Kanamycin and tobramycin derivatives,their preparation and pharmaceutical compositions containing them
IL48905A0 (en)	1976-03-31	New oxadiazolinone derivatives,their preparation and pesticidal compositions containing them
IL60918A (en)	1983-11-30	6-pyridazinones,their preparation and pharmaceutical compositions containing them
IL49325A (en)	1979-11-30	8-aza-11-deoxy-pge1 derivatives,their preparation and pharmaceutical compositions containing them
IL57297A (en)	1983-02-23	4-amino-2-piperidinoquinazoline derivatives,their preparation and pharmaceutical compositions containing them
IL60307A0 (en)	1980-09-16	Alkoxybenzylpyridopyrimidines,their preparation and pharmaceutical compositions containing them
IL52857A (en)	1983-03-31	Oxo-benzopyrane derivatives,their preparation and pharmaceutical compositions containing them
IL60058A0 (en)	1980-07-31	Hydroxyamino-eburnane derivatives,their preparation and pharmaceutical compositions containing them
IL60359A (en)	1985-04-30	Dialkylaminoalkoxyiminocycloalkane derivatives,their preparation and pharmaceutical compositions containing them
IL58620A (en)	1982-12-31	Aryltrifluoroethanol derivatives,their preparation and pharmaceutical compositions containing them
IL56816A0 (en)	1979-05-31	N-phenylaniline derivatives,their preparation and pharmaceutical compositions containing them
IL60927A (en)	1984-04-30	Amino-propanoloxytetrahydroquinoline derivatives,their preparation and pharmaceutical compositions containing them
IL56890A0 (en)	1979-05-31	2-amino-carbazole derivatives,their preparation and pharmaceutical compositions containing them
IL56913A (en)	1982-08-31	Sprio-steroid-oxazolidinone derivatives,their preparation and pharmaceutical compositions containing them
IL57667A (en)	1983-06-15	2-azaergolines and 2-aza-8-ergolines,their preparation and pharmaceutical compositions containing them
DE2963868D1 (en)	1982-11-25	Carbostyrile derivatives, their preparation and pharmaceutical compositions containing them