IL42698A - 7-(n-methyl-n-(beta-phenylethyl)-3-aminopropyl)-theophylline derivatives - Google Patents
7-(n-methyl-n-(beta-phenylethyl)-3-aminopropyl)-theophylline derivativesInfo
- Publication number
- IL42698A IL42698A IL42698A IL4269873A IL42698A IL 42698 A IL42698 A IL 42698A IL 42698 A IL42698 A IL 42698A IL 4269873 A IL4269873 A IL 4269873A IL 42698 A IL42698 A IL 42698A
- Authority
- IL
- Israel
- Prior art keywords
- compounds
- general formula
- theophylline
- pharmaceutical
- compound
- Prior art date
Links
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims abstract 2
- 150000001875 compounds Chemical class 0.000 claims 8
- 238000000034 method Methods 0.000 claims 5
- ZFXYFBGIUFBOJW-UHFFFAOYSA-N theophylline Chemical compound O=C1N(C)C(=O)N(C)C2=C1NC=N2 ZFXYFBGIUFBOJW-UHFFFAOYSA-N 0.000 claims 5
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 claims 3
- 230000001558 histaminolytic effect Effects 0.000 claims 2
- 229960000278 theophylline Drugs 0.000 claims 2
- 239000004480 active ingredient Substances 0.000 claims 1
- -1 benzylcarboxy groups Chemical group 0.000 claims 1
- 125000000051 benzyloxy group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])O* 0.000 claims 1
- 150000002170 ethers Chemical class 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 2
- 229910052801 chlorine Inorganic materials 0.000 abstract 2
- 239000000460 chlorine Substances 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 230000003266 anti-allergic effect Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 239000011737 fluorine Substances 0.000 abstract 1
- 239000000932 sedative agent Substances 0.000 abstract 1
- 230000001624 sedative effect Effects 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
- C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Pulmonology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2239012A DE2239012A1 (de) | 1972-08-08 | 1972-08-08 | Basisch substituierte theophyllinabkoemmlinge |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL42698A0 IL42698A0 (en) | 1973-10-25 |
| IL42698A true IL42698A (en) | 1976-07-30 |
Family
ID=5853037
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL42698A IL42698A (en) | 1972-08-08 | 1973-07-10 | 7-(n-methyl-n-(beta-phenylethyl)-3-aminopropyl)-theophylline derivatives |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US3926995A (es) |
| JP (1) | JPS5714350B2 (es) |
| KR (1) | KR780000273B1 (es) |
| AR (4) | AR206916A1 (es) |
| AT (3) | AT328465B (es) |
| AU (1) | AU473294B2 (es) |
| BE (1) | BE801893A (es) |
| CA (1) | CA998669A (es) |
| CH (4) | CH591483A5 (es) |
| CS (1) | CS189616B2 (es) |
| DD (1) | DD107044A5 (es) |
| DE (1) | DE2239012A1 (es) |
| DK (1) | DK131187B (es) |
| ES (1) | ES415782A1 (es) |
| FI (1) | FI58640C (es) |
| FR (1) | FR2195441B1 (es) |
| GB (1) | GB1431587A (es) |
| HU (1) | HU170289B (es) |
| IE (1) | IE37899B1 (es) |
| IL (1) | IL42698A (es) |
| NL (1) | NL7310951A (es) |
| NO (1) | NO137900C (es) |
| SE (1) | SE400081B (es) |
| SU (5) | SU504490A3 (es) |
| YU (3) | YU206473A (es) |
| ZA (1) | ZA735400B (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS49121524U (es) * | 1973-02-12 | 1974-10-17 | ||
| JPS5242609U (es) * | 1975-09-20 | 1977-03-26 | ||
| JPS62277347A (ja) * | 1986-02-25 | 1987-12-02 | Microbial Chem Res Found | 新規生理活性物質ア−ブスタチン類縁化合物 |
| JPS6332704A (ja) * | 1986-07-26 | 1988-02-12 | Sony Corp | 回転磁気ヘツド装置 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3245994A (en) * | 1966-04-12 | Theophylline derivatives | ||
| US3036083A (en) * | 1959-05-15 | 1962-05-22 | Ciba Geigy Corp | Certain 2-pyridyl lower alkyl guanidines |
| FR1352320A (fr) * | 1963-02-13 | 1964-02-14 | Degussa | Procédé de préparation de dérivés alcoylxanthiniques à substituants basiques |
| DE1237578B (de) * | 1963-05-10 | 1967-03-30 | Knoll Ag | Verfahren zur Herstellung basisch substituierter Xanthinderivate |
| NL6708305A (es) * | 1966-06-23 | 1967-12-27 | ||
| DE2021620C3 (de) * | 1970-05-02 | 1980-02-07 | Boehringer Sohn Ingelheim | Neue Phenylaminoalkane und Verfahren zu deren Herstellung |
-
1972
- 1972-08-08 DE DE2239012A patent/DE2239012A1/de not_active Withdrawn
-
1973
- 1973-06-09 ES ES415782A patent/ES415782A1/es not_active Expired
- 1973-07-04 BE BE133097A patent/BE801893A/xx unknown
- 1973-07-10 IE IE1167/73A patent/IE37899B1/xx unknown
- 1973-07-10 IL IL42698A patent/IL42698A/en unknown
- 1973-07-11 GB GB3306073A patent/GB1431587A/en not_active Expired
- 1973-07-25 SU SU1952731A patent/SU504490A3/ru active
- 1973-07-30 YU YU02064/73A patent/YU206473A/xx unknown
- 1973-08-02 AT AT257975*7A patent/AT328465B/de not_active IP Right Cessation
- 1973-08-02 AT AT678473A patent/AT327218B/de not_active IP Right Cessation
- 1973-08-02 AT AT257875*7A patent/AT328464B/de not_active IP Right Cessation
- 1973-08-03 CH CH1131073A patent/CH591483A5/xx not_active IP Right Cessation
- 1973-08-03 CH CH1635576A patent/CH590865A5/xx not_active IP Right Cessation
- 1973-08-03 CH CH1635476A patent/CH591484A5/xx not_active IP Right Cessation
- 1973-08-03 US US385320A patent/US3926995A/en not_active Expired - Lifetime
- 1973-08-03 CH CH1635676A patent/CH591485A5/xx not_active IP Right Cessation
- 1973-08-07 CA CA178,272A patent/CA998669A/en not_active Expired
- 1973-08-07 DK DK432873AA patent/DK131187B/da unknown
- 1973-08-07 SE SE7310820A patent/SE400081B/xx unknown
- 1973-08-07 HU HUKO2608A patent/HU170289B/hu unknown
- 1973-08-07 DD DD172740A patent/DD107044A5/xx unknown
- 1973-08-07 NO NO3153/73A patent/NO137900C/no unknown
- 1973-08-08 KR KR7301292A patent/KR780000273B1/ko active
- 1973-08-08 FI FI2480/73A patent/FI58640C/fi active
- 1973-08-08 JP JP8916873A patent/JPS5714350B2/ja not_active Expired
- 1973-08-08 FR FR7329014A patent/FR2195441B1/fr not_active Expired
- 1973-08-08 AU AU59028/73A patent/AU473294B2/en not_active Expired
- 1973-08-08 NL NL7310951A patent/NL7310951A/xx not_active Application Discontinuation
- 1973-08-08 CS CS735619A patent/CS189616B2/cs unknown
- 1973-08-08 ZA ZA735400A patent/ZA735400B/xx unknown
-
1974
- 1974-10-09 SU SU2065464A patent/SU507242A3/ru active
- 1974-10-09 SU SU2065457A patent/SU507241A3/ru active
- 1974-10-09 SU SU2066925A patent/SU507243A3/ru active
- 1974-10-09 SU SU2065458A patent/SU526291A3/ru active
-
1975
- 1975-01-01 AR AR257923A patent/AR206916A1/es active
- 1975-01-01 AR AR257921A patent/AR206914A1/es active
- 1975-01-01 AR AR257922A patent/AR206915A1/es active
- 1975-01-01 AR AR257920A patent/AR206913A1/es active
-
1979
- 1979-09-07 YU YU02176/79A patent/YU217679A/xx unknown
- 1979-09-07 YU YU02177/79A patent/YU217779A/xx unknown
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