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IL30458A - 6-chloro-2,3,4,5-tetrahydro-1h-3-benzazepine,its preparation and compositions containing it - Google Patents

6-chloro-2,3,4,5-tetrahydro-1h-3-benzazepine,its preparation and compositions containing it

Info

Publication number
IL30458A
IL30458A IL30458A IL3045868A IL30458A IL 30458 A IL30458 A IL 30458A IL 30458 A IL30458 A IL 30458A IL 3045868 A IL3045868 A IL 3045868A IL 30458 A IL30458 A IL 30458A
Authority
IL
Israel
Prior art keywords
tetrahydro
benzazepine
acid
chloro
salt
Prior art date
Application number
IL30458A
Other languages
English (en)
Other versions
IL30458A0 (en
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of IL30458A0 publication Critical patent/IL30458A0/xx
Publication of IL30458A publication Critical patent/IL30458A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL30458A 1968-02-09 1968-07-29 6-chloro-2,3,4,5-tetrahydro-1h-3-benzazepine,its preparation and compositions containing it IL30458A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH197668A CH498122A (de) 1968-02-09 1968-02-09 Verfahren zur Herstellung eines neuen Tetrahydroazepinderivates

Publications (2)

Publication Number Publication Date
IL30458A0 IL30458A0 (en) 1968-09-26
IL30458A true IL30458A (en) 1972-03-28

Family

ID=4223010

Family Applications (1)

Application Number Title Priority Date Filing Date
IL30458A IL30458A (en) 1968-02-09 1968-07-29 6-chloro-2,3,4,5-tetrahydro-1h-3-benzazepine,its preparation and compositions containing it

Country Status (10)

Country Link
AT (1) AT277257B (fi)
BE (1) BE719631A (fi)
CH (1) CH498122A (fi)
DE (1) DE1795132A1 (fi)
DK (1) DK123526B (fi)
ES (1) ES357247A1 (fi)
FR (1) FR1598948A (fi)
GB (1) GB1225053A (fi)
IL (1) IL30458A (fi)
NL (1) NL6811311A (fi)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2171879A1 (en) * 1972-02-14 1973-09-28 Pennwalt Corp 1,2,4,5-tetrahydro-3h-3-benzazepines - analgesics narcotic antagonists, antihistamines etc
US4160765A (en) * 1976-11-17 1979-07-10 Smithkline Corporation Method for 6-bromination of 1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine compounds
US4197297A (en) * 1976-11-17 1980-04-08 Smithkline Corporation 6-Halo-7,8-dihydroxy-1-(hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepines
US4171359A (en) * 1978-04-12 1979-10-16 Smithkline Corporation Benz-tetrasubstituted 1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines
US6953787B2 (en) 2002-04-12 2005-10-11 Arena Pharmaceuticals, Inc. 5HT2C receptor modulators
EA016558B1 (ru) 2003-06-17 2012-05-30 Арена Фармасьютикалз, Инк. Производные бензазепина, используемые для лечения заболеваний, ассоциированных с 5-ht-рецептором
AU2004267016B2 (en) 2003-06-17 2011-11-24 Arena Pharmaceuticals, Inc. Benzazepine derivatives useful for the treatment of 5HT2C receptor associated diseases
TW200510324A (en) * 2003-08-11 2005-03-16 Lilly Co Eli 6-(2,2,2-trifluoroethylamino)-7-chiloro-2, 3, 4, 5-tetrahydro-1h-benzo[d]azepine as a 5-ht2c receptor agonist
KR101281919B1 (ko) 2004-12-21 2013-07-03 아레나 파마슈티칼스, 인크. (ｒ)-8-클로로-1-메틸-2,3,4,5-테트라히드로-1ｈ-3-벤즈아제핀 히드로클로라이드의 결정질 형태
KR101426850B1 (ko) 2004-12-23 2014-08-05 아레나 파마슈티칼스, 인크. 5ｈｔ２ｃ 수용체 조정물질 조성물 및 그의 사용 방법
JP5199997B2 (ja) 2006-04-03 2013-05-15 アリーナ ファーマシューティカルズ， インコーポレイテッド ８−クロロ−１−メチル−２，３，４，５−テトラヒドロ−１ｈ−３−ベンズアゼピンおよびこれに関連する中間体を調製するためのプロセス
ES2522587T3 (es) 2006-12-05 2014-11-17 Arena Pharmaceuticals, Inc. Procesos para preparar (R)-8-cloro-1-metil-2,3,4,5-tetrahidro-1H-3-benzacepina e intermedios de la misma
WO2009111004A1 (en) 2008-03-04 2009-09-11 Arena Pharmaceuticals, Inc. Processes for the preparation of intermediates related to the 5-ht2c agonist (r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine
WO2010148207A2 (en) 2009-06-18 2010-12-23 Arena Pharmaceuticals, Inc. Processes for the preparation of 5-ht2c receptor agonists
KR20130112848A (ko) 2010-06-02 2013-10-14 아레나 파마슈티칼스, 인크. 5-ｈｔ2ｃ 수용체 아고니스트의 제조 방법
WO2012030957A2 (en) 2010-09-01 2012-03-08 Arena Pharmaceuticals, Inc. Non-hygroscopic salts of 5-ht2c agonists
KR20140091458A (ko) 2010-09-01 2014-07-21 아레나 파마슈티칼스, 인크. 신장 손상을 갖는 개체에 대한 로카세린의 투여
JP6272695B2 (ja) 2010-09-01 2018-01-31 エーザイ・アール・アンド・ディー・マネジメント株式会社 体重管理のために有用な５−ｈｔ２ｃアゴニストの改変放出剤形
WO2012030938A1 (en) 2010-09-01 2012-03-08 Arena Pharmaceuticals, Inc. Salts of lorcaserin with optically active acids
CA2886875A1 (en) 2012-10-09 2014-04-17 Arena Pharmaceuticals, Inc. Method of weight management

Also Published As

Publication number Publication date
ES357247A1 (es) 1970-03-01
AT277257B (de) 1969-12-29
DK123526B (da) 1972-07-03
NL6811311A (fi) 1969-08-12
GB1225053A (en) 1971-03-17
FR1598948A (fi) 1970-07-15
IL30458A0 (en) 1968-09-26
CH498122A (de) 1970-10-31
DE1795132A1 (de) 1972-01-05
BE719631A (fi) 1969-02-17

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