IL159014A0 - Use of il-18 inhibitors for treating or preventing cns injuries - Google Patents

Use of il-18 inhibitors for treating or preventing cns injuries

Info

Publication number: IL159014A0
Authority: IL; Israel
Prior art keywords: inhibitors; treating; cns injuries; preventing cns; preventing
Prior art date: 2001-05-25

Application number

IL15901402A

Other languages

English (en)

Original Assignee

Ares Trading Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-05-25

Filing date

2002-05-23

Publication date

2004-05-12

2002-05-23 Application filed by Ares Trading Sa filed Critical Ares Trading Sa

2004-05-12 Publication of IL159014A0 publication Critical patent/IL159014A0/xx

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Immunology (AREA)
Neurosurgery (AREA)
Microbiology (AREA)
Mycology (AREA)
Epidemiology (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Cardiology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Heart & Thoracic Surgery (AREA)
Hospice & Palliative Care (AREA)
Rheumatology (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicinal Preparation (AREA)

IL15901402A 2001-05-25 2002-05-23 Use of il-18 inhibitors for treating or preventing cns injuries IL159014A0 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP01112067		2001-05-25
PCT/EP2002/005666 WO2002096456A1 (en)	2001-05-25	2002-05-23	Use of il-18 inhibitors for treating or preventing cns injuries

Publications (1)

Publication Number	Publication Date
IL159014A0 true IL159014A0 (en)	2004-05-12

Family

ID=8177454

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
IL15901402A IL159014A0 (en)	2001-05-25	2002-05-23	Use of il-18 inhibitors for treating or preventing cns injuries
IL159014A IL159014A (en)	2001-05-25	2003-11-23	Use of IL-18 inhibitors for the manufacture of a medicament for the treatment and / or prevention of traumatic brain injury

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
IL159014A IL159014A (en)	2001-05-25	2003-11-23	Use of IL-18 inhibitors for the manufacture of a medicament for the treatment and / or prevention of traumatic brain injury

Country Status (30)

Country	Link
US (1)	US7655616B2 (xx)
EP (1)	EP1390070B1 (xx)
JP (1)	JP4344142B2 (xx)
KR (1)	KR20040030625A (xx)
CN (1)	CN1305529C (xx)
AU (1)	AU2002314103B2 (xx)
BG (1)	BG66395B1 (xx)
BR (1)	BR0210007A (xx)
CA (1)	CA2445664C (xx)
CY (1)	CY1119190T1 (xx)
CZ (1)	CZ307321B6 (xx)
DK (1)	DK1390070T3 (xx)
EA (1)	EA006744B1 (xx)
EE (1)	EE05263B1 (xx)
ES (1)	ES2617084T3 (xx)
HK (1)	HK1069762A1 (xx)
HR (1)	HRP20030842B1 (xx)
HU (1)	HU230294B1 (xx)
IL (2)	IL159014A0 (xx)
LT (1)	LT1390070T (xx)
ME (1)	ME00550B (xx)
MX (1)	MXPA03010743A (xx)
NO (1)	NO331882B1 (xx)
PL (1)	PL216228B1 (xx)
PT (1)	PT1390070T (xx)
RS (1)	RS56006B1 (xx)
SK (1)	SK288413B6 (xx)
UA (1)	UA80396C2 (xx)
WO (1)	WO2002096456A1 (xx)
ZA (1)	ZA200308172B (xx)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2384241T3 (es)	2003-05-13	2012-07-02	Merck Serono Sa	Variantes activas de la proteína que fija IL-18 y usos médicos de las mismas
AU2005258569B2 (en) *	2004-06-30	2012-05-03	Atsuo Sekiyama	Indicator agent for noninflammatory stress response and use thereof
ES2370417T3 (es)	2005-06-03	2011-12-15	Ares Trading S.A.	Producción de una proteína de unión a il-18 recombinante.
CA2610691C (en) *	2005-06-03	2015-12-01	Laboratoires Serono S.A.	Use of il-18bp isoforms for the treatment and/or prevention of neurological inflammatory diseases
PL1891088T3 (pl)	2005-06-10	2012-03-30	Ares Trading Sa	Sposób oczyszczania białka wiążącego IL-18
US8685400B2 (en) *	2007-07-30	2014-04-01	University Of Miami	Modulating inflammasome activity and inflammation in the central nervous system
ES2892923T3 (es) *	2013-09-05	2022-02-07	Ab2 Bio Sa	Proteína de unión a IL-18 (IL-18BP) en enfermedades inflamatorias
AU2016227644B2 (en)	2015-03-05	2022-06-16	Ab2 Bio Sa	IL-18 Binding Protein (IL-18BP) and antibodies in inflammatory diseases

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH0873453A (ja) *	1994-09-02	1996-03-19	Otsuka Pharmaceut Co Ltd	サイトカイン阻害剤
IL121860A0 (en) *	1997-08-14	1998-02-22	Yeda Res & Dev	Interleukin-18 binding proteins their preparation and use
ES2244178T3 (es) *	1998-03-09	2005-12-01	Vertex Pharmaceuticals Incorporated	Derivados de 1,2-diazepan como inhibidores de la enzima convertidora de interleuquina-1 beta.
CA2276216A1 (en) *	1998-06-24	1999-12-24	Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo	An artificial peptide capable of neutralizing the biological activity of interleukin-18
EA007014B1 (ru)	2000-05-05	2006-06-30	Апплайд Резеч Системз Арс Холдинг Н.В.	Применение il-18 в качестве диагностического маркера
EP1292288B1 (en) *	2000-06-23	2004-09-29	Yissum Research Development Company Of The Hebrew University Of Jerusalem	2-arachidonylglycerol (2-ag) - an inhibitor of tumor necrosis factor -alfa and neuroprotector of brain in closed head injury
AU2002224417A1 (en) *	2000-10-18	2002-04-29	Immunex Corporation	Methods for treating il-18 mediated disorders
US6671553B1 (en) *	2001-05-23	2003-12-30	Pacesetter, Inc.	Implantable cardiac lead having terminating connector strain relief and method of manufacture

2002
- 2002-05-23 RS YU89403A patent/RS56006B1/sr unknown
- 2002-05-23 PL PL367545A patent/PL216228B1/pl unknown
- 2002-05-23 LT LTEP02740641.2T patent/LT1390070T/lt unknown
- 2002-05-23 DK DK02740641.2T patent/DK1390070T3/en active
- 2002-05-23 MX MXPA03010743A patent/MXPA03010743A/es active IP Right Grant
- 2002-05-23 KR KR10-2003-7015310A patent/KR20040030625A/ko active Search and Examination
- 2002-05-23 EP EP02740641.2A patent/EP1390070B1/en not_active Expired - Lifetime
- 2002-05-23 EE EEP200300582A patent/EE05263B1/xx unknown
- 2002-05-23 CN CNB028147510A patent/CN1305529C/zh not_active Expired - Lifetime
- 2002-05-23 CZ CZ2003-3268A patent/CZ307321B6/cs not_active IP Right Cessation
- 2002-05-23 ME MEP-2008-618A patent/ME00550B/me unknown
- 2002-05-23 BR BR0210007-0A patent/BR0210007A/pt not_active Application Discontinuation
- 2002-05-23 EA EA200301299A patent/EA006744B1/ru not_active IP Right Cessation
- 2002-05-23 CA CA2445664A patent/CA2445664C/en not_active Expired - Lifetime
- 2002-05-23 SK SK1603-2003A patent/SK288413B6/sk not_active IP Right Cessation
- 2002-05-23 UA UA20031212328A patent/UA80396C2/uk unknown
- 2002-05-23 JP JP2002592965A patent/JP4344142B2/ja not_active Expired - Lifetime
- 2002-05-23 HU HU0304067A patent/HU230294B1/hu unknown
- 2002-05-23 WO PCT/EP2002/005666 patent/WO2002096456A1/en active IP Right Grant
- 2002-05-23 IL IL15901402A patent/IL159014A0/xx unknown
- 2002-05-23 US US10/478,614 patent/US7655616B2/en not_active Expired - Lifetime
- 2002-05-23 AU AU2002314103A patent/AU2002314103B2/en not_active Expired
- 2002-05-23 PT PT2740641T patent/PT1390070T/pt unknown
- 2002-05-23 ES ES02740641.2T patent/ES2617084T3/es not_active Expired - Lifetime
2003
- 2003-10-17 HR HRP20030842AA patent/HRP20030842B1/hr not_active IP Right Cessation
- 2003-10-21 ZA ZA200308172A patent/ZA200308172B/xx unknown
- 2003-11-20 NO NO20035160A patent/NO331882B1/no not_active IP Right Cessation
- 2003-11-23 IL IL159014A patent/IL159014A/en active IP Right Grant
- 2003-12-15 BG BG108451A patent/BG66395B1/bg unknown
2004
- 2004-12-31 HK HK04110391A patent/HK1069762A1/xx not_active IP Right Cessation
2017
- 2017-05-08 CY CY20171100494T patent/CY1119190T1/el unknown

Also Published As

Publication number	Publication date
EA006744B1 (ru)	2006-04-28
BR0210007A (pt)	2004-08-10
HK1069762A1 (en)	2005-06-03
WO2002096456A1 (en)	2002-12-05
US20040191247A1 (en)	2004-09-30
LT1390070T (lt)	2017-03-10
US7655616B2 (en)	2010-02-02
HRP20030842B1 (hr)	2017-06-02
RS56006B1 (sr)	2017-09-29
CN1535160A (zh)	2004-10-06
CN1305529C (zh)	2007-03-21
HUP0304067A2 (hu)	2004-03-29
PL216228B1 (pl)	2014-03-31
HUP0304067A3 (en)	2006-01-30
CZ307321B6 (cs)	2018-06-06
ME00550B (me)	2011-10-10
EA200301299A1 (ru)	2004-04-29
CZ20033268A3 (en)	2004-07-14
HU230294B1 (hu)	2015-12-28
CY1119190T1 (el)	2018-02-14
IL159014A (en)	2012-05-31
MXPA03010743A (es)	2004-03-02
PL367545A1 (en)	2005-02-21
BG108451A (en)	2005-02-28
DK1390070T3 (en)	2017-04-24
SK288413B6 (sk)	2016-10-03
KR20040030625A (ko)	2004-04-09
EE200300582A (et)	2004-02-16
EP1390070A1 (en)	2004-02-25
AU2002314103B2 (en)	2007-07-12
HRP20030842A2 (en)	2005-08-31
BG66395B1 (bg)	2013-12-31
NO331882B1 (no)	2012-04-23
ES2617084T3 (es)	2017-06-15
AU2002314103B8 (en)	2002-12-09
NO20035160L (no)	2003-11-20
CA2445664C (en)	2012-03-06
JP4344142B2 (ja)	2009-10-14
CA2445664A1 (en)	2002-12-05
UA80396C2 (en)	2007-09-25
EP1390070B1 (en)	2017-02-08
SK16032003A3 (sk)	2004-05-04
YU89403A (sh)	2006-05-25
JP2004534777A (ja)	2004-11-18
ZA200308172B (en)	2004-10-21
NO20035160D0 (no)	2003-11-20
EE05263B1 (et)	2010-02-15
PT1390070T (pt)	2017-03-01

Publication	Publication Date	Title
HK1094909A1 (en)	2007-04-13	Use of il-18 inhibitors for the treatment and/or prevention of atherosclerosis il-18
HK1061030A1 (en)	2004-09-03	Rho-kinase inhibitors
HK1061029A1 (en)	2004-09-03	Rho-kinase inhibitors
IL157657A0 (en)	2004-03-28	Metalloproteinase inhibitors
IL157570A0 (en)	2004-03-28	Metalloproteinase inhibitors
HUP0402075A3 (en)	2008-04-28	Compositions for treatment of common cold
IL157658A0 (en)	2004-03-28	Metalloproteinase inhibitors
HUP0300061A3 (en)	2005-09-28	Use of il-18 inhibitors
EP1337255A4 (en)	2006-01-25	USE OF P38 INHIBITORS FOR THE TREATMENT OF INFLAMMATORY COUGH
HK1068551A1 (en)	2005-04-29	Substituted benzimidazole compounds and their use for the treatment of cancer
AU7753401A (en)	2002-02-05	Method for locating compounds which are suitable for the treatment and/or prophylaxis of obesity
EP1359885A4 (en)	2005-03-16	NOS-HEMMER FOR THE TREATMENT OF WRINKLES
HK1062810A1 (en)	2004-11-26	Use of il-18 inhibitors for the manufacture of medicaments for treatment and/or prevention of heartdisease
HUP0304067A3 (en)	2006-01-30	Use of il-18 inhibitors for treating or preventing cns injuries
HUP0302430A3 (en)	2009-08-28	Use of 1-phenyl-3-dimethylaminopropane compounds for treating urinary incontience
IL157588A0 (en)	2004-03-28	Carbamate compounds for use in preventing or treating psychotic disorders
IL160230A0 (en)	2004-07-25	Use of il-18 inhibitors
SI1458703T1 (sl)	2007-08-31	Izokromanske spojine za zdravljenje motenj centralnega živčnega sistema
IL161630A0 (en)	2004-09-27	Methods of treating endometreosis
GB0119460D0 (en)	2001-10-03	The use of inhibitors of the renin-angiotensin system
EP1557169A4 (en)	2010-09-22	THERAPEUTIC AND / OR PROPHYLACTIC AGENT FOR DYSCHEZIA
AU2002360614A8 (en)	2003-06-30	Methods of inhibiting fertility
GB0129388D0 (en)	2002-01-30	Use of compounds for treating cancer
SI1307262T1 (en)	2005-02-28	Method for locating compounds which are suitable for the treatment and/or prophylaxis of obesity
GB0100646D0 (en)	2001-02-21	Compositions for therapy and prophylaxis