IL158642A0 - Naphthothiazine positive allosteric ampa receptor modulators (paarm) - Google Patents
Naphthothiazine positive allosteric ampa receptor modulators (paarm)Info
- Publication number
- IL158642A0 IL158642A0 IL15864202A IL15864202A IL158642A0 IL 158642 A0 IL158642 A0 IL 158642A0 IL 15864202 A IL15864202 A IL 15864202A IL 15864202 A IL15864202 A IL 15864202A IL 158642 A0 IL158642 A0 IL 158642A0
- Authority
- IL
- Israel
- Prior art keywords
- paarm
- naphthothiazine
- receptor modulators
- positive allosteric
- ampa receptor
- Prior art date
Links
- GQHZLGWQGWYNFO-UHFFFAOYSA-N 3h-benzo[f][1,2]benzothiazine Chemical compound C1=CC=CC2=C(C=CNS3)C3=CC=C21 GQHZLGWQGWYNFO-UHFFFAOYSA-N 0.000 title 1
- 102000003678 AMPA Receptors Human genes 0.000 title 1
- 108090000078 AMPA Receptors Proteins 0.000 title 1
- 230000003281 allosteric effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D279/02—1,2-Thiazines; Hydrogenated 1,2-thiazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychiatry (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10123952A DE10123952A1 (en) | 2001-05-17 | 2001-05-17 | New naphtho-1,2-thiazine compounds, useful as neuroprotectants for treating e.g. epilepsy or Alzheimer's disease, are allosteric modulators of AMPA receptors |
| PCT/EP2002/005338 WO2002100411A1 (en) | 2001-05-17 | 2002-05-15 | Naphtothiazine positive allosteric ampa receptor modulators (paarm) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL158642A0 true IL158642A0 (en) | 2004-05-12 |
Family
ID=7685080
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL15864202A IL158642A0 (en) | 2001-05-17 | 2002-05-15 | Naphthothiazine positive allosteric ampa receptor modulators (paarm) |
Country Status (26)
| Country | Link |
|---|---|
| EP (1) | EP1404340A1 (en) |
| JP (1) | JP2004529980A (en) |
| KR (1) | KR20040007572A (en) |
| CN (1) | CN1533278A (en) |
| AR (1) | AR036332A1 (en) |
| BG (1) | BG108324A (en) |
| BR (1) | BR0209796A (en) |
| CA (1) | CA2449189A1 (en) |
| CO (1) | CO5550460A2 (en) |
| CZ (1) | CZ20033112A3 (en) |
| DE (1) | DE10123952A1 (en) |
| EA (1) | EA006608B1 (en) |
| EC (1) | ECSP034852A (en) |
| EE (1) | EE200300566A (en) |
| HR (1) | HRP20030933A2 (en) |
| HU (1) | HUP0401273A3 (en) |
| IL (1) | IL158642A0 (en) |
| MX (1) | MXPA03010373A (en) |
| NO (1) | NO20035088L (en) |
| NZ (1) | NZ530154A (en) |
| PL (1) | PL364053A1 (en) |
| SK (1) | SK14222003A3 (en) |
| UY (1) | UY27290A1 (en) |
| WO (1) | WO2002100411A1 (en) |
| YU (1) | YU90403A (en) |
| ZA (1) | ZA200308466B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20090047534A (en) * | 2006-08-31 | 2009-05-12 | 더 거버너스 오브 더 유니버시티 오브 앨버타 | Inhibition of respiratory depression using positive allosteric APMPA receptor modulators |
| CN111518058B (en) * | 2020-05-29 | 2021-03-09 | 四川大学华西医院 | Oxathiazine compound and application thereof |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU4345297A (en) * | 1996-09-17 | 1998-04-14 | Regents Of The University Of California, The | Benzothiadiazide derivatives and their use as allosteric up-modulators of the ampa receptor |
| WO1999067242A1 (en) * | 1998-06-25 | 1999-12-29 | Merck & Co., Inc. | Naphtho[1,8-de]thiasin-2-yl methyl carbapenem antibacterials |
| DE10004572A1 (en) * | 2000-02-02 | 2001-08-09 | Boehringer Ingelheim Pharma | New positive allosteric AMPA receptor modulators (PAARM), processes for their production and their use as medicines |
-
2001
- 2001-05-17 DE DE10123952A patent/DE10123952A1/en not_active Withdrawn
-
2002
- 2002-05-15 EP EP02750931A patent/EP1404340A1/en not_active Withdrawn
- 2002-05-15 JP JP2003503232A patent/JP2004529980A/en not_active Abandoned
- 2002-05-15 IL IL15864202A patent/IL158642A0/en unknown
- 2002-05-15 BR BR0209796-6A patent/BR0209796A/en not_active Expired - Fee Related
- 2002-05-15 EE EEP200300566A patent/EE200300566A/en unknown
- 2002-05-15 KR KR10-2003-7014965A patent/KR20040007572A/en not_active Application Discontinuation
- 2002-05-15 MX MXPA03010373A patent/MXPA03010373A/en unknown
- 2002-05-15 PL PL02364053A patent/PL364053A1/en not_active Application Discontinuation
- 2002-05-15 YU YU90403A patent/YU90403A/en unknown
- 2002-05-15 WO PCT/EP2002/005338 patent/WO2002100411A1/en not_active Application Discontinuation
- 2002-05-15 CN CNA028100832A patent/CN1533278A/en active Pending
- 2002-05-15 UY UY27290A patent/UY27290A1/en not_active Application Discontinuation
- 2002-05-15 CZ CZ20033112A patent/CZ20033112A3/en unknown
- 2002-05-15 HU HU0401273A patent/HUP0401273A3/en unknown
- 2002-05-15 NZ NZ530154A patent/NZ530154A/en unknown
- 2002-05-15 SK SK1422-2003A patent/SK14222003A3/en unknown
- 2002-05-15 CA CA002449189A patent/CA2449189A1/en not_active Abandoned
- 2002-05-15 EA EA200301167A patent/EA006608B1/en not_active IP Right Cessation
- 2002-05-17 AR ARP020101827A patent/AR036332A1/en not_active Suspension/Interruption
-
2003
- 2003-10-30 ZA ZA200308466A patent/ZA200308466B/en unknown
- 2003-11-07 BG BG108324A patent/BG108324A/en active Pending
- 2003-11-14 NO NO20035088A patent/NO20035088L/en not_active Application Discontinuation
- 2003-11-14 HR HR20030933A patent/HRP20030933A2/en not_active Application Discontinuation
- 2003-11-17 EC EC2003004852A patent/ECSP034852A/en unknown
- 2003-12-01 CO CO03105591A patent/CO5550460A2/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EE200300566A (en) | 2004-02-16 |
| EA200301167A1 (en) | 2004-06-24 |
| AR036332A1 (en) | 2004-09-01 |
| BG108324A (en) | 2004-12-30 |
| NO20035088D0 (en) | 2003-11-14 |
| CA2449189A1 (en) | 2002-12-19 |
| CO5550460A2 (en) | 2005-08-31 |
| PL364053A1 (en) | 2004-12-13 |
| EA006608B1 (en) | 2006-02-24 |
| CZ20033112A3 (en) | 2004-03-17 |
| WO2002100411A1 (en) | 2002-12-19 |
| SK14222003A3 (en) | 2004-05-04 |
| EP1404340A1 (en) | 2004-04-07 |
| YU90403A (en) | 2006-05-25 |
| ECSP034852A (en) | 2003-12-24 |
| DE10123952A1 (en) | 2002-11-21 |
| JP2004529980A (en) | 2004-09-30 |
| HUP0401273A2 (en) | 2004-10-28 |
| KR20040007572A (en) | 2004-01-24 |
| ZA200308466B (en) | 2004-05-24 |
| HRP20030933A2 (en) | 2004-04-30 |
| MXPA03010373A (en) | 2004-03-16 |
| NO20035088L (en) | 2003-11-14 |
| UY27290A1 (en) | 2002-12-31 |
| HUP0401273A3 (en) | 2006-11-28 |
| NZ530154A (en) | 2005-09-30 |
| CN1533278A (en) | 2004-09-29 |
| BR0209796A (en) | 2004-06-01 |
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