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IL147575A - Method for purifying keratinocyte growth factors - Google Patents

Method for purifying keratinocyte growth factors

Info

Publication number
IL147575A
IL147575A IL14757595A IL14757595A IL147575A IL 147575 A IL147575 A IL 147575A IL 14757595 A IL14757595 A IL 14757595A IL 14757595 A IL14757595 A IL 14757595A IL 147575 A IL147575 A IL 147575A
Authority
IL
Israel
Prior art keywords
kgf
seq
solution
oxidized
cation exchange
Prior art date
Application number
IL14757595A
Other languages
English (en)
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/487,830 external-priority patent/US6008328A/en
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of IL147575A publication Critical patent/IL147575A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • C07K14/50Fibroblast growth factor [FGF]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL14757595A 1994-10-13 1995-10-12 Method for purifying keratinocyte growth factors IL147575A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US32333994A 1994-10-13 1994-10-13
US08/487,830 US6008328A (en) 1994-10-13 1995-06-07 Method for purifying keratinocyte growth factors
IL11560595A IL115605A (en) 1994-10-13 1995-10-12 Method for purifying keratinocyte growth factors

Publications (1)

Publication Number Publication Date
IL147575A true IL147575A (en) 2004-05-12

Family

ID=26983902

Family Applications (3)

Application Number Title Priority Date Filing Date
IL11560595A IL115605A (en) 1994-10-13 1995-10-12 Method for purifying keratinocyte growth factors
IL14757595A IL147575A (en) 1994-10-13 1995-10-12 Method for purifying keratinocyte growth factors
IL14757502A IL147575A0 (en) 1994-10-13 2002-01-10 Method for purifying keratinocyte growth factors

Family Applications Before (1)

Application Number Title Priority Date Filing Date
IL11560595A IL115605A (en) 1994-10-13 1995-10-12 Method for purifying keratinocyte growth factors

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL14757502A IL147575A0 (en) 1994-10-13 2002-01-10 Method for purifying keratinocyte growth factors

Country Status (18)

Country Link
EP (2) EP0785949B1 (ja)
JP (1) JP3877226B2 (ja)
CN (1) CN1161380C (ja)
AT (1) ATE239038T1 (ja)
CA (1) CA2201762C (ja)
CZ (1) CZ98297A3 (ja)
DE (2) DE122006000019I1 (ja)
DK (1) DK0785949T3 (ja)
ES (1) ES2197926T3 (ja)
HU (1) HU220584B1 (ja)
IL (3) IL115605A (ja)
LU (1) LU91235I2 (ja)
NL (1) NL300229I2 (ja)
NO (1) NO971567L (ja)
PT (1) PT785949E (ja)
SI (1) SI0785949T1 (ja)
SK (1) SK43097A3 (ja)
WO (1) WO1996011952A1 (ja)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6693077B1 (en) 1995-02-14 2004-02-17 Human Genome Sciences, Inc. Keratinocyte growth factor-2
US6077692A (en) 1995-02-14 2000-06-20 Human Genome Sciences, Inc. Keratinocyte growth factor-2
US7232667B2 (en) 1995-02-14 2007-06-19 Human Genome Sciences, Inc. Keratinocyte growth factor-2 polynucleotides
US6743422B1 (en) 1996-10-15 2004-06-01 Amgen, Inc. Keratinocyte growth factor-2 products
CN1283997A (zh) 1997-12-22 2001-02-14 人类基因组科学公司 角质形成细胞生长因子-2制剂
US6869927B1 (en) 1997-12-22 2005-03-22 Human Genome Sciences, Inc. Keratinocyte growth factor-2 formulations
CN1491231A (zh) * 2001-02-06 2004-04-21 Ĭ��ר�����޹�˾ 免疫原性减弱的经修饰角质形成细胞生长因子(kgf)
WO2003016505A2 (en) * 2001-08-21 2003-02-27 Chiron Corporation Kgf polypeptide compositions
CN102242124B (zh) * 2010-05-10 2013-05-22 齐鲁制药有限公司 改造的角化细胞生长因子基因及其在酵母中的表达
CN102675449B (zh) * 2011-03-17 2016-06-08 重庆富进生物医药有限公司 缺失型人角质细胞生长因子-ⅰ二硫键变构体及其用途
CN109402130A (zh) * 2018-11-23 2019-03-01 成都中医药大学附属医院 一种重组人角质细胞生长因子-1及其制备方法和用途
CN110183529B (zh) * 2019-05-23 2023-06-02 重庆派金生物科技有限公司 一种缺失型人角质细胞生长因子-1的重组制备方法
KR20230127721A (ko) * 2022-02-25 2023-09-01 한국해양과학기술원 온도안정성을 향상시킨 fgf7 폴리펩타이드 및 그 용도

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2153816T3 (es) * 1989-01-31 2001-03-16 Jeffrey S Rubin Adn que codifica un factor de crecimiento especifico contra celulas epiteliales.
IE914393A1 (en) * 1990-12-18 1992-07-01 Amgen Inc Analogs of acidic fibroblast growth factor having enhanced¹stability and biological activity
SK153295A3 (en) * 1993-06-29 1996-11-06 Chiron Corp A truncated keratinocyte growth factor (kgf) having increased biological activity
AU687455B2 (en) * 1993-09-24 1998-02-26 Wyeth Holdings Corporation Surface loop structural analogues of fibroblast growth factors
WO1996011949A2 (en) * 1994-10-13 1996-04-25 Amgen Inc. Analogs of keratinocyte growth factor
WO1996022369A1 (en) * 1994-10-13 1996-07-25 Amgen Inc. Analogs of acidic fibroblast growth factor having enhanced stability and biological activity
EP0785950B1 (en) * 1994-10-13 2003-04-16 Amgen Inc., Keratinocyte growth factor analogs

Also Published As

Publication number Publication date
IL115605A0 (en) 1996-01-19
SI0785949T1 (en) 2003-08-31
PT785949E (pt) 2003-09-30
NL300229I1 (nl) 2006-06-01
EP0785949B1 (en) 2003-05-02
DE69530599D1 (de) 2003-06-05
IL115605A (en) 2003-06-24
DK0785949T3 (da) 2003-08-18
IL147575A0 (en) 2002-08-14
HUT76879A (en) 1997-12-29
LU91235I2 (fr) 2006-11-22
MX9702481A (es) 1997-07-31
EP0785949A1 (en) 1997-07-30
CZ98297A3 (cs) 1998-08-12
EP1334981B1 (en) 2011-01-26
DE122006000019I1 (de) 2006-06-29
ES2197926T3 (es) 2004-01-16
AU709362B2 (en) 1999-08-26
CN1161380C (zh) 2004-08-11
JP3877226B2 (ja) 2007-02-07
AU3830695A (en) 1996-05-06
CA2201762C (en) 2001-12-18
CN1169734A (zh) 1998-01-07
EP1334981A3 (en) 2004-05-06
ATE239038T1 (de) 2003-05-15
CA2201762A1 (en) 1996-04-25
NO971567D0 (no) 1997-04-04
NL300229I2 (nl) 2006-09-01
SK43097A3 (en) 1998-10-07
WO1996011952A1 (en) 1996-04-25
JPH10507452A (ja) 1998-07-21
NO971567L (no) 1997-06-12
EP1334981A2 (en) 2003-08-13
HU220584B1 (hu) 2002-03-28
DE69530599T2 (de) 2003-11-13

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Legal Events

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KB Patent renewed
KB Patent renewed
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MM9K Patent not in force due to non-payment of renewal fees