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IL142757A0 - Use of staurosporine derivatives for treating ocular neovascular diseases - Google Patents

Use of staurosporine derivatives for treating ocular neovascular diseases

Info

Publication number
IL142757A0
IL142757A0 IL14275799A IL14275799A IL142757A0 IL 142757 A0 IL142757 A0 IL 142757A0 IL 14275799 A IL14275799 A IL 14275799A IL 14275799 A IL14275799 A IL 14275799A IL 142757 A0 IL142757 A0 IL 142757A0
Authority
IL
Israel
Prior art keywords
treating ocular
ocular neovascular
neovascular diseases
staurosporine derivatives
treating
Prior art date
Application number
IL14275799A
Other languages
English (en)
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of IL142757A0 publication Critical patent/IL142757A0/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/553Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL14275799A 1998-11-23 1999-11-22 Use of staurosporine derivatives for treating ocular neovascular diseases IL142757A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19867798A 1998-11-23 1998-11-23
PCT/EP1999/008987 WO2000030651A1 (en) 1998-11-23 1999-11-22 Use of staurosporine derivatives for treating ocular neovascular diseases

Publications (1)

Publication Number Publication Date
IL142757A0 true IL142757A0 (en) 2002-03-10

Family

ID=22734344

Family Applications (2)

Application Number Title Priority Date Filing Date
IL14275799A IL142757A0 (en) 1998-11-23 1999-11-22 Use of staurosporine derivatives for treating ocular neovascular diseases
IL142757A IL142757A (en) 1998-11-23 2001-04-23 Use in the history of staurosporine for the preparation of drugs for the treatment of diseases caused by the production of blood vessels in the eye

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL142757A IL142757A (en) 1998-11-23 2001-04-23 Use in the history of staurosporine for the preparation of drugs for the treatment of diseases caused by the production of blood vessels in the eye

Country Status (19)

Country Link
EP (1) EP1131073B1 (pt)
JP (2) JP2002530342A (pt)
KR (1) KR100698449B1 (pt)
CN (1) CN1172673C (pt)
AT (1) ATE252387T1 (pt)
AU (1) AU761092B2 (pt)
BR (1) BR9915569A (pt)
CA (1) CA2348890C (pt)
DE (1) DE69912304T2 (pt)
DK (1) DK1131073T3 (pt)
ES (1) ES2211197T3 (pt)
HK (1) HK1040182A1 (pt)
ID (1) ID29970A (pt)
IL (2) IL142757A0 (pt)
NO (1) NO328085B1 (pt)
NZ (1) NZ511559A (pt)
PT (1) PT1131073E (pt)
WO (1) WO2000030651A1 (pt)
ZA (1) ZA200103925B (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0122318D0 (en) * 2001-09-14 2001-11-07 Novartis Ag Organic compounds
US20030119812A1 (en) * 2001-11-08 2003-06-26 Brazzell Romulus Kimbro Method for decreasing capillary permeability in the retina
AU2003254566A1 (en) * 2002-07-23 2004-02-09 Novartis Ag Ophtalmic ointment composition comprising a drug, an ointment base and a solubiling/dispersing agent
MX2007001155A (es) * 2004-07-29 2007-08-14 Creabilis Therapeutics Spa Uso de inhibidores de k-252a y de quinasa para la prevencion o el tratamiento de patologias asociadas con hmgb1.
CN101580515B (zh) * 2008-05-16 2011-06-08 上海医药工业研究院 一种星形孢菌素提取纯化的方法
WO2010104933A1 (en) 2009-03-11 2010-09-16 Merck Sharp & Dohme Corp. Inhibitors of akt activity
US8691825B2 (en) 2009-04-01 2014-04-08 Merck Sharp & Dohme Corp. Inhibitors of AKT activity
CN102924479A (zh) * 2011-08-09 2013-02-13 山东鲁北药业有限公司 一种星孢菌素类衍生物的半合成方法
EP2755482B1 (en) 2011-09-15 2016-06-01 Merck Sharp & Dohme Corp. Combination of mk-1775 and mk-8776 for treating cancer
DK2925888T3 (en) 2012-11-28 2017-12-18 Merck Sharp & Dohme COMPOSITIONS AND METHODS OF CANCER TREATMENT

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL86632A0 (en) * 1987-06-15 1988-11-30 Ciba Geigy Ag Derivatives substituted at methyl-amino nitrogen
US5093330A (en) * 1987-06-15 1992-03-03 Ciba-Geigy Corporation Staurosporine derivatives substituted at methylamino nitrogen
WO1994001124A1 (en) * 1992-07-08 1994-01-20 Celtrix Pharmaceuticals, Inc. METHOD OF TREATING OPHTHALMIC DISORDERS USING TGF-$g(b)
US6410322B1 (en) * 1993-07-27 2002-06-25 Hybridon Inc Antisense oligonucleotide inhibition of vascular endothelial growth factor expression
WO1997034920A1 (en) * 1996-03-21 1997-09-25 Sugen, Inc. Assays for kdr/flk-1 receptor tyrosine kinase inhibitors
UA54427C2 (uk) * 1996-05-01 2003-03-17 Елі Ліллі Енд Компані Спосіб лікування очних захворювань, які пов'язані з фактором васкулярного ендотеліального росту
EP1806135A3 (en) * 1998-03-13 2010-11-24 The Johns Hopkins University School Of Medicine The use of a protein tyrosine inhibitor such as genistein in the treatment of diabetic retinopathy or ocular inflammation

Also Published As

Publication number Publication date
NO20012490L (no) 2001-06-25
EP1131073A1 (en) 2001-09-12
CA2348890C (en) 2009-05-12
CA2348890A1 (en) 2000-06-02
ES2211197T3 (es) 2004-07-01
EP1131073B1 (en) 2003-10-22
PT1131073E (pt) 2004-03-31
JP2011088938A (ja) 2011-05-06
CN1328462A (zh) 2001-12-26
CN1172673C (zh) 2004-10-27
ID29970A (id) 2001-10-25
DE69912304T2 (de) 2004-07-22
DE69912304D1 (de) 2003-11-27
ZA200103925B (en) 2002-07-25
BR9915569A (pt) 2001-08-14
AU761092B2 (en) 2003-05-29
KR100698449B1 (ko) 2007-03-23
WO2000030651A1 (en) 2000-06-02
IL142757A (en) 2007-07-04
ATE252387T1 (de) 2003-11-15
KR20010078398A (ko) 2001-08-20
JP2002530342A (ja) 2002-09-17
DK1131073T3 (da) 2004-02-02
HK1040182A1 (en) 2002-05-31
NO328085B1 (no) 2009-11-30
AU1506600A (en) 2000-06-13
NZ511559A (en) 2004-01-30
NO20012490D0 (no) 2001-05-21

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Legal Events

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