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IL129547A - Pharmaceutical compositions comprising a macrolide and an acid - Google Patents

Pharmaceutical compositions comprising a macrolide and an acid

Info

Publication number
IL129547A
IL129547A IL12954795A IL12954795A IL129547A IL 129547 A IL129547 A IL 129547A IL 12954795 A IL12954795 A IL 12954795A IL 12954795 A IL12954795 A IL 12954795A IL 129547 A IL129547 A IL 129547A
Authority
IL
Israel
Prior art keywords
macrolide
acid
pharmaceutical compositions
provides
dimethyisosorbide
Prior art date
Application number
IL12954795A
Other languages
English (en)
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9421613A external-priority patent/GB9421613D0/en
Priority claimed from GB9422084A external-priority patent/GB9422084D0/en
Priority claimed from GBGB9425353.1A external-priority patent/GB9425353D0/en
Priority claimed from GBGB9517133.6A external-priority patent/GB9517133D0/en
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of IL129547A publication Critical patent/IL129547A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Rheumatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Dermatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Transplantation (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Colloid Chemistry (AREA)
  • Cosmetics (AREA)
IL12954795A 1994-10-26 1995-10-24 Pharmaceutical compositions comprising a macrolide and an acid IL129547A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB9421613A GB9421613D0 (en) 1994-10-26 1994-10-26 Organic compounds
GB9422084A GB9422084D0 (en) 1994-11-02 1994-11-02 Organic compounds
GBGB9425353.1A GB9425353D0 (en) 1994-12-15 1994-12-15 Organic compounds
GBGB9517133.6A GB9517133D0 (en) 1995-08-22 1995-08-22 Pharmaceutical compositions
IL11574295A IL115742A (en) 1994-10-26 1995-10-24 Pharmaceutical compositions comprising a difficultly soluble active agent a hydrophilic phase a lipophilic phase and a surfactant

Publications (1)

Publication Number Publication Date
IL129547A true IL129547A (en) 2001-01-11

Family

ID=27451224

Family Applications (3)

Application Number Title Priority Date Filing Date
IL12954795A IL129547A (en) 1994-10-26 1995-10-24 Pharmaceutical compositions comprising a macrolide and an acid
IL11574295A IL115742A (en) 1994-10-26 1995-10-24 Pharmaceutical compositions comprising a difficultly soluble active agent a hydrophilic phase a lipophilic phase and a surfactant
IL12954799A IL129547A0 (en) 1994-10-26 1999-04-22 Pharmaceutical compositions comprising a macrolide and an acid

Family Applications After (2)

Application Number Title Priority Date Filing Date
IL11574295A IL115742A (en) 1994-10-26 1995-10-24 Pharmaceutical compositions comprising a difficultly soluble active agent a hydrophilic phase a lipophilic phase and a surfactant
IL12954799A IL129547A0 (en) 1994-10-26 1999-04-22 Pharmaceutical compositions comprising a macrolide and an acid

Country Status (25)

Country Link
EP (2) EP0787011B1 (zh)
JP (3) JPH10509699A (zh)
KR (2) KR100541198B1 (zh)
CN (3) CN1679938A (zh)
AT (1) ATE411800T1 (zh)
AU (1) AU714360B2 (zh)
BR (1) BR9509496A (zh)
CA (1) CA2200967C (zh)
CY (1) CY2210B1 (zh)
CZ (1) CZ289838B6 (zh)
DE (2) DE69535869D1 (zh)
ES (1) ES2316150T3 (zh)
FI (1) FI119497B (zh)
HU (1) HU225535B1 (zh)
IL (3) IL129547A (zh)
MY (1) MY129435A (zh)
NO (2) NO323078B1 (zh)
NZ (1) NZ295655A (zh)
PE (1) PE52896A1 (zh)
PL (1) PL184368B1 (zh)
PT (1) PT787011E (zh)
SK (2) SK286178B6 (zh)
TR (2) TR199500299A2 (zh)
TW (1) TW308544B (zh)
WO (1) WO1996013273A1 (zh)

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Also Published As

Publication number Publication date
CN1124157C (zh) 2003-10-15
JP2004359696A (ja) 2004-12-24
DE69535869D1 (de) 2008-12-04
NZ295655A (en) 1998-12-23
TR199501321A2 (tr) 1996-06-21
CY2210B1 (en) 2002-11-08
PL319691A1 (en) 1997-08-18
CA2200967A1 (en) 1996-05-09
AU714360B2 (en) 1999-12-23
CZ123197A3 (en) 1997-07-16
HU225535B1 (en) 2007-02-28
CZ289838B6 (cs) 2002-04-17
EP0787011A1 (en) 1997-08-06
IL129547A0 (en) 2000-02-29
NO323063B1 (no) 2006-12-27
KR100518135B1 (ko) 2005-10-04
MX9702701A (es) 1997-10-31
CN1404833A (zh) 2003-03-26
NO20031901D0 (no) 2003-04-28
TR199500299A2 (tr) 1997-06-23
EP2039358A1 (en) 2009-03-25
PT787011E (pt) 2009-01-23
ES2316150T3 (es) 2009-04-01
NO323078B1 (no) 2006-12-27
DE19581805T1 (de) 1997-10-16
SK52197A3 (en) 1997-09-10
EP0787011B1 (en) 2008-10-22
KR20040074104A (ko) 2004-08-21
IL115742A (en) 2000-06-01
CA2200967C (en) 2007-09-25
AU3924895A (en) 1996-05-23
IL115742A0 (en) 1996-01-19
BR9509496A (pt) 1997-09-30
FI970995A0 (fi) 1997-03-10
KR100541198B1 (ko) 2007-04-11
KR970706837A (ko) 1997-12-01
ATE411800T1 (de) 2008-11-15
SK286178B6 (sk) 2008-04-07
PE52896A1 (es) 1996-12-12
TW308544B (zh) 1997-06-21
JP2005247870A (ja) 2005-09-15
JPH10509699A (ja) 1998-09-22
HUT76858A (en) 1997-12-29
MY129435A (en) 2007-04-30
CN1161652A (zh) 1997-10-08
NO971898L (no) 1997-06-24
NO20031901L (no) 1997-06-24
FI970995A (fi) 1997-04-25
NO971898D0 (no) 1997-04-24
WO1996013273A1 (en) 1996-05-09
SK285809B6 (sk) 2007-08-02
PL184368B1 (pl) 2002-10-31
FI119497B (fi) 2008-12-15
CN1679938A (zh) 2005-10-12

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