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IL128103A0 - The use of proteinase inhibitors for prevention or reduction of bone resorption - Google Patents

The use of proteinase inhibitors for prevention or reduction of bone resorption

Info

Publication number
IL128103A0
IL128103A0 IL12810397A IL12810397A IL128103A0 IL 128103 A0 IL128103 A0 IL 128103A0 IL 12810397 A IL12810397 A IL 12810397A IL 12810397 A IL12810397 A IL 12810397A IL 128103 A0 IL128103 A0 IL 128103A0
Authority
IL
Israel
Prior art keywords
prevention
reduction
bone resorption
proteinase inhibitors
proteinase
Prior art date
Application number
IL12810397A
Other languages
English (en)
Original Assignee
Ct For Clinical & Basic Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ct For Clinical & Basic Res filed Critical Ct For Clinical & Basic Res
Priority to IL14529797A priority Critical patent/IL145297A0/xx
Publication of IL128103A0 publication Critical patent/IL128103A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/8146—Metalloprotease (E.C. 3.4.24) inhibitors, e.g. tissue inhibitor of metallo proteinase, TIMP

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Rheumatology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Analytical Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
IL12810397A 1996-07-30 1997-07-29 The use of proteinase inhibitors for prevention or reduction of bone resorption IL128103A0 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IL14529797A IL145297A0 (en) 1996-07-30 1997-07-29 Use of an agent for the manufacture of a medicament for the treatment of bone diseases

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9615976.9A GB9615976D0 (en) 1996-07-30 1996-07-30 The use of proteinase inhibitors for the prevention or reduction of bone resorption
PCT/EP1997/004110 WO1998004287A1 (en) 1996-07-30 1997-07-29 The use of proteinase inhibitors for prevention or reduction of bone resorption

Publications (1)

Publication Number Publication Date
IL128103A0 true IL128103A0 (en) 1999-11-30

Family

ID=10797737

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12810397A IL128103A0 (en) 1996-07-30 1997-07-29 The use of proteinase inhibitors for prevention or reduction of bone resorption

Country Status (9)

Country Link
EP (1) EP0915709A1 (xx)
JP (1) JP2001501594A (xx)
CN (1) CN1226174A (xx)
AU (1) AU733104B2 (xx)
BR (1) BR9710615A (xx)
CA (1) CA2261567A1 (xx)
GB (1) GB9615976D0 (xx)
IL (1) IL128103A0 (xx)
WO (1) WO1998004287A1 (xx)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000061623A1 (en) * 1999-04-09 2000-10-19 Human Genome Sciences, Inc. 62 human secreted proteins
US6277061B1 (en) 1998-03-31 2001-08-21 The Research Foundation Of State University Of New York Method of inhibiting membrane-type matrix metalloproteinase
WO2000040600A1 (en) * 1998-12-31 2000-07-13 Aventis Pharmaceuticals Inc. Selective inhibitors of mmp-12
US6352976B1 (en) 1998-12-31 2002-03-05 Aventis Pharmaceuticals Inc. Selective inhibitors of MMP-12
FR2802945A1 (fr) * 1999-12-28 2001-06-29 Pf Medicament Nouvelle metalloprotease matricielle mmp-25 homologue de la matrilysine
ES2219521T3 (es) * 2000-04-05 2004-12-01 Ipf Pharmaceuticals Gmbh Medicamento que contiene un inhibidor tisular de metaloproteinasas-2 (timp-2) como sustancia osteoanabolicamente activa.
EP1288297A4 (en) * 2000-05-19 2004-11-17 Daiichi Fine Chem Co Ltd REGULATION OF MT1-MMP ACTIVITY
US7071164B2 (en) 2001-08-16 2006-07-04 Kimberly-Clark Worldwide, Inc. Anti-cancer and wound healing compounds
US6906036B2 (en) 2001-08-16 2005-06-14 Kimberly-Clark Worldwide, Inc. Anti-aging and wound healing compounds
US7094754B2 (en) 2001-08-16 2006-08-22 Kimberly-Clark Worldwide, Inc. Anti-aging and wound healing compounds
US7186693B2 (en) 2001-08-16 2007-03-06 Kimberly - Clark Worldwide, Inc. Metalloproteinase inhibitors for wound healing
CA2493232A1 (en) * 2002-07-18 2004-01-29 Index Pharmaceuticals Ab Antisense compounds, methods and compositions for treating mmp-12 related inflammatory disorders
US7148194B2 (en) 2002-12-30 2006-12-12 Kimberly-Clark Worldwide, Inc. Method to increase fibronectin
US7189700B2 (en) 2003-06-20 2007-03-13 Kimberly-Clark Worldwide, Inc. Anti-chrondrosarcoma compounds
CA2635588C (en) 2005-12-30 2015-11-10 Dyax Corp. Metalloproteinase binding proteins
AU2008338421A1 (en) * 2007-12-17 2009-06-25 Dyax Corp. Compositions and methods for treating osteolytic disorders comprising MMP-14 binding proteins
EP2262530A4 (en) * 2008-03-03 2012-12-05 Dyax Corp Metalloproteinase-12 TIE PROTEINS
WO2013059439A2 (en) 2011-10-21 2013-04-25 Dyax Corp. Combination therapy comprising an mmp-14 binding protein
EP2907512A1 (en) 2014-02-14 2015-08-19 Commissariat A L'energie Atomique Et Aux Energies Alternatives Inhibitors of MMP-12 as antiviral Agents
KR101576904B1 (ko) * 2014-07-31 2015-12-14 (주)케어젠 파골세포 분화 및 활성 억제능을 갖는 펩타이드 및 이의 용도

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2848232B2 (ja) * 1993-02-19 1999-01-20 武田薬品工業株式会社 アルデヒド誘導体
EP0685557B1 (en) * 1993-11-30 1998-08-12 Fuji Yakuhin Kogyo Kabushiki Kaisha Novel metalloprotease and dna coding for the same

Also Published As

Publication number Publication date
GB9615976D0 (en) 1996-09-11
EP0915709A1 (en) 1999-05-19
CN1226174A (zh) 1999-08-18
AU733104B2 (en) 2001-05-10
BR9710615A (pt) 2000-01-11
CA2261567A1 (en) 1998-02-05
AU4203297A (en) 1998-02-20
WO1998004287A1 (en) 1998-02-05
JP2001501594A (ja) 2001-02-06

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