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IL125800A0 - Thermally stabilized contrast agent - Google Patents

Thermally stabilized contrast agent

Info

Publication number
IL125800A0
IL125800A0 IL12580097A IL12580097A IL125800A0 IL 125800 A0 IL125800 A0 IL 125800A0 IL 12580097 A IL12580097 A IL 12580097A IL 12580097 A IL12580097 A IL 12580097A IL 125800 A0 IL125800 A0 IL 125800A0
Authority
IL
Israel
Prior art keywords
contrast agent
thermally stabilized
stabilized contrast
freeze
thermally
Prior art date
Application number
IL12580097A
Other languages
English (en)
Original Assignee
Nycomed Imaging As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9603466.5A external-priority patent/GB9603466D0/en
Priority claimed from GBGB9611894.8A external-priority patent/GB9611894D0/en
Priority claimed from GBGB9624919.8A external-priority patent/GB9624919D0/en
Application filed by Nycomed Imaging As filed Critical Nycomed Imaging As
Publication of IL125800A0 publication Critical patent/IL125800A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/227—Liposomes, lipoprotein vesicles, e.g. LDL or HDL lipoproteins, micelles, e.g. phospholipidic or polymeric

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Acoustics & Sound (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Light Receiving Elements (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
IL12580097A 1996-02-19 1997-02-19 Thermally stabilized contrast agent IL125800A0 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB9603466.5A GB9603466D0 (en) 1996-02-19 1996-02-19 Improvements in or relating to contrast agents
GBGB9611894.8A GB9611894D0 (en) 1996-06-07 1996-06-07 Improvements in or relating to contrast agents
GBGB9624919.8A GB9624919D0 (en) 1996-11-29 1996-11-29 Product
PCT/GB1997/000458 WO1997029782A1 (en) 1996-02-19 1997-02-19 Thermally stabilized contrast agent

Publications (1)

Publication Number Publication Date
IL125800A0 true IL125800A0 (en) 1999-04-11

Family

ID=27268136

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12580097A IL125800A0 (en) 1996-02-19 1997-02-19 Thermally stabilized contrast agent

Country Status (18)

Country Link
EP (1) EP0885016B1 (de)
JP (1) JP4250747B2 (de)
KR (1) KR100501863B1 (de)
CN (1) CN1092988C (de)
AT (1) ATE237362T1 (de)
AU (1) AU722735B2 (de)
CA (1) CA2246778A1 (de)
CZ (1) CZ262698A3 (de)
DE (1) DE69720979T2 (de)
EA (1) EA000900B1 (de)
EE (1) EE9800248A (de)
ES (1) ES2197331T3 (de)
HU (1) HUP9900812A3 (de)
IL (1) IL125800A0 (de)
NO (1) NO313815B1 (de)
NZ (1) NZ331372A (de)
PL (1) PL328309A1 (de)
WO (1) WO1997029782A1 (de)

Families Citing this family (44)

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MXPA99001053A (es) 1996-08-02 2002-03-11 Nycomed Imaging As Mejoramientos en o que se relacionan con agentes de contraste.
GB9717542D0 (en) 1997-08-19 1997-10-22 Nycomed Imaging As Process
BR0112417A (pt) 2000-07-13 2003-07-01 Daiichi Seiyaku Co Composições farmacêuticas contendo composto dds
US6793626B2 (en) 2001-01-17 2004-09-21 Fuji Photo Film Co., Ltd. Ultrasonic scatterer, ultrasonic imaging method and ultrasonic imaging apparatus
DE60111917T2 (de) * 2001-01-31 2006-04-20 Bracco International B.V. Lyophilisierbares Kontrastmittel, gasgefüllte Mikrobläschen enthaltend
KR101280760B1 (ko) 2002-11-29 2013-07-05 지이 헬스케어 에이에스 초음파 조영 물질
ATE480263T1 (de) * 2003-02-04 2010-09-15 Bracco Suisse Sa Ultraschall kontrastmittel und verfahren zur erstellung
US9750821B2 (en) 2003-12-22 2017-09-05 Bracco Suisse S.A. Gas-filled microvesicle assembly for contrast imaging
CN103120799A (zh) 2004-08-18 2013-05-29 博莱科瑞士股份有限公司 用于反差成像的充气微泡组合物
WO2006076826A1 (fr) * 2005-01-18 2006-07-27 Institute Of Pharmacology Toxicology, Academy Of Military Medical Sciences Composition de contraste pour ultrasons utilisant un phospholipide filmogene et procede de preparation de celle-ci
WO2008028917A1 (en) 2006-09-05 2008-03-13 Bracco Research Sa Gas-filled microvesicles with polymer-modified lipids
WO2008075192A2 (en) 2006-12-19 2008-06-26 Bracco International Bv Targeting and therapeutic compounds and gas-filled microvesicles comprising said com ounds
EP2187909A1 (de) 2007-09-11 2010-05-26 Mondobiotech Laboratories AG Verwendung von bpp-b als therapeutisches mittel
JP2010539022A (ja) 2007-09-11 2010-12-16 モンドバイオテック ラボラトリーズ アクチエンゲゼルシャフト 治療剤としての、ｃ型ナトリウム利尿ペプチド単独または神経ペプチドａｆとの組合せの使用
JP2010539065A (ja) 2007-09-11 2010-12-16 モンドバイオテック ラボラトリーズ アクチエンゲゼルシャフト 治療剤としてのペプチドの使用
WO2009033764A2 (en) 2007-09-11 2009-03-19 Mondobiotech Laboratories Ag Use of a peptide as a therapeutic agent
US20100197586A1 (en) 2007-09-11 2010-08-05 Dorian Bevec Use of secretin and optionally urodilatin as therapeutic agents
WO2009043464A2 (en) 2007-09-11 2009-04-09 Mondobiotech Laboratories Ag Astressin and beta- endorphin for use as therapeutic agents
JP5384502B2 (ja) 2007-09-11 2014-01-08 モンドバイオテック ラボラトリーズ アクチエンゲゼルシャフト 治療剤としてのソマトスタチン−１４の使用
JP2010539052A (ja) 2007-09-11 2010-12-16 モンドバイオテック ラボラトリーズ アクチエンゲゼルシャフト 治療剤としてのペプチドの使用
WO2009040073A2 (en) 2007-09-11 2009-04-02 Mondobiotech Laboratories Ag Use of a peptide as a therapeutic agent
AU2008303900A1 (en) 2007-09-11 2009-04-02 Mondobiotech Laboratories Ag Use of a galanin peptide as a therapeutic agent
RU2010114044A (ru) 2007-09-11 2011-10-20 Мондобайотек Лабораториз Аг (Li) Применение белка полосы 3 (824-829) и/или фактора ингибирования высвобождения меланотропина в качестве терапевтического средства при лечении инфекции pseudomonas aeruginosa
US20100273701A1 (en) 2007-09-11 2010-10-28 Dorian Bevec Use of salusin beta alone or in combination with octreotide as a therapeutic agent
EP2090322A1 (de) 2008-02-18 2009-08-19 INSERM (Institut National de la Santé et de la Recherche Médicale) Verwendung von FSH-Rezeptorliganden zur Diagnose und Behandlung von Krebs
EP2346532B1 (de) 2008-10-07 2020-10-07 Bracco Suisse SA Target-konstrukt mit einem anti-polymer-antikörper und an diesen bindende mikrovesikel
CN101649293B (zh) * 2009-09-02 2012-07-18 中国农业大学 一种微生物冷冻干燥保护剂及其应用
US9211348B2 (en) 2010-08-09 2015-12-15 Bracco Suisse S.A. Targeted gas-filled microvesicles
EP2426202A1 (de) 2010-09-03 2012-03-07 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Kinasen als Targets für antidiabetische Therapien
BR112013016244B1 (pt) 2010-12-24 2021-12-21 Bracco Suisse Sa Formulação farmacêutica compreendendo microvesículas cheias de gás e precursor da mesma
RU2648753C2 (ru) * 2011-10-21 2018-03-28 Селатор Фармасьютикалз Инк. Лиофилизированные липосомы
EP2589383A1 (de) 2011-11-06 2013-05-08 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Berlin FKBP-subtypspezifisches Rapamycin-Analogon zur Verwendung bei der Behandlung von Erkrankungen
GB201405735D0 (en) * 2014-03-31 2014-05-14 Ge Healthcare As Ultrasound precursor preparation method
GB201411423D0 (en) * 2014-06-26 2014-08-13 Ge Healthcare As Lipid sterilisation method
EP3020813A1 (de) 2014-11-16 2016-05-18 Neurovision Pharma GmbH Antisense-Oligonukleotide als Inhibitoren der TGF-R-Signalgebung
US10537622B2 (en) 2014-12-22 2020-01-21 Bracco Suisse S.A. Gas-filled microvesicles for use as vaccine
US20190117800A1 (en) * 2016-04-19 2019-04-25 Microvascuar Therapeutics Llc Systems and methods for filling vials with gases
IL277165B2 (en) 2018-03-07 2024-07-01 Bracco Suisse Sa Preparation of size-controlled microvesicles
CN114025807A (zh) * 2019-06-25 2022-02-08 博莱科瑞士股份有限公司 用于制备标准化充气微泡的冻干组合物
US20220409749A1 (en) * 2019-06-25 2022-12-29 Bracco Suisse Sa Freeze-dried composition for preparing calibrated gas-filled microvesicles
US10953023B1 (en) 2020-01-28 2021-03-23 Applaud Medical, Inc. Phospholipid compounds and formulations
CN112891565A (zh) * 2021-04-09 2021-06-04 上海师范大学 锌-二甲基吡啶胺在制备诊断血栓性疾病药物中的应用
EP4105328A1 (de) 2021-06-15 2022-12-21 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Antisense-oligonukleotide zur prävention von nierenfunktionsstörungen, die durch endotheliale dysfunktion gefördert werden, durch unterdrückung von ephrin-b2
CN117797279A (zh) * 2023-11-07 2024-04-02 浙江普利药业有限公司 一种荧光-磁共振双模态造影剂及其制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4857319A (en) * 1985-01-11 1989-08-15 The Regents Of The University Of California Method for preserving liposomes
US4642903A (en) * 1985-03-26 1987-02-17 R. P. Scherer Corporation Freeze-dried foam dosage form
JPH06211645A (ja) * 1993-01-14 1994-08-02 Mitsubishi Kasei Corp リポソーム凍結乾燥製剤

Also Published As

Publication number Publication date
AU722735B2 (en) 2000-08-10
CN1213971A (zh) 1999-04-14
DE69720979T2 (de) 2004-02-26
DE69720979D1 (de) 2003-05-22
WO1997029782A1 (en) 1997-08-21
EP0885016A1 (de) 1998-12-23
EA199800739A1 (ru) 1999-02-25
PL328309A1 (en) 1999-01-18
EA000900B1 (ru) 2000-06-26
KR19990082670A (ko) 1999-11-25
NO983584D0 (no) 1998-08-05
EE9800248A (et) 1999-02-15
NO983584L (no) 1998-10-16
ATE237362T1 (de) 2003-05-15
CA2246778A1 (en) 1997-08-21
JP2000506122A (ja) 2000-05-23
NZ331372A (en) 2000-01-28
NO313815B1 (no) 2002-12-09
HUP9900812A2 (hu) 1999-07-28
CZ262698A3 (cs) 1999-03-17
AU1805197A (en) 1997-09-02
HUP9900812A3 (en) 1999-11-29
CN1092988C (zh) 2002-10-23
ES2197331T3 (es) 2004-01-01
EP0885016B1 (de) 2003-04-16
KR100501863B1 (ko) 2005-09-27
JP4250747B2 (ja) 2009-04-08

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees