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IL117067A - Anti-neurodegeneratively active 10-aminoaliphatyl-dibenz¬b,f¾oxepines their preparation and pharmaceutical compositions containing them - Google Patents

Anti-neurodegeneratively active 10-aminoaliphatyl-dibenz¬b,f¾oxepines their preparation and pharmaceutical compositions containing them

Info

Publication number
IL117067A
IL117067A IL11706796A IL11706796A IL117067A IL 117067 A IL117067 A IL 117067A IL 11706796 A IL11706796 A IL 11706796A IL 11706796 A IL11706796 A IL 11706796A IL 117067 A IL117067 A IL 117067A
Authority
IL
Israel
Prior art keywords
aminoaliphatyl
dibenz
preparation
pharmaceutical compositions
compositions containing
Prior art date
Application number
IL11706796A
Other languages
English (en)
Other versions
IL117067A0 (en
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of IL117067A0 publication Critical patent/IL117067A0/xx
Publication of IL117067A publication Critical patent/IL117067A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/02—Seven-membered rings
    • C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D313/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D313/14—[b,f]-condensed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrane Compounds (AREA)
  • Epoxy Compounds (AREA)
IL11706796A 1995-02-08 1996-02-07 Anti-neurodegeneratively active 10-aminoaliphatyl-dibenz¬b,f¾oxepines their preparation and pharmaceutical compositions containing them IL117067A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH36795 1995-02-08

Publications (2)

Publication Number Publication Date
IL117067A0 IL117067A0 (en) 1996-06-18
IL117067A true IL117067A (en) 2000-08-13

Family

ID=4185416

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11706796A IL117067A (en) 1995-02-08 1996-02-07 Anti-neurodegeneratively active 10-aminoaliphatyl-dibenz¬b,f¾oxepines their preparation and pharmaceutical compositions containing them

Country Status (27)

Country Link
US (2) US5780500A (pt)
EP (1) EP0726265B1 (pt)
JP (2) JP3625559B2 (pt)
KR (1) KR100485538B1 (pt)
CN (1) CN1216052C (pt)
AR (1) AR004474A1 (pt)
AT (1) ATE203528T1 (pt)
AU (1) AU715245B2 (pt)
BR (1) BR9600339A (pt)
CA (1) CA2168937C (pt)
CY (1) CY2333B1 (pt)
DE (1) DE59607332D1 (pt)
DK (1) DK0726265T3 (pt)
ES (1) ES2160790T3 (pt)
FI (1) FI120400B (pt)
GR (1) GR3036656T3 (pt)
HU (1) HU229227B1 (pt)
IL (1) IL117067A (pt)
MX (1) MX9600503A (pt)
MY (1) MY113427A (pt)
NO (1) NO314356B1 (pt)
NZ (1) NZ280940A (pt)
PT (1) PT726265E (pt)
RU (1) RU2160734C2 (pt)
SA (1) SA01220313A (pt)
TW (1) TW420672B (pt)
ZA (1) ZA96960B (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5840749A (en) * 1989-08-25 1998-11-24 Hoechst Marion Roussel, Inc. N-hydroxy-dibenz b,e!oxepinalkylamines, N-hydroxy-dibenz b,e!oxepinalkanoic acid amides and related heterocyclic analogues
AR008371A1 (es) * 1996-05-30 2000-01-19 Novartis Ag Una sal de adicion con acido de una 10-aminoalifatil-dibenz[b,f],oxepina, su empleo; procedimiento para su elaboracion, una 10-aminoalifatil-dibenz[b,f]oxepina, una preparacion farmaceutica que contiene dicha sal o dicha oxepina y un procedimiento para el tratamiento de enfermedades neurodegenerativ
WO1997046549A1 (en) * 1996-06-05 1997-12-11 Novartis Ag Anti-neurodegeneratively effective xanthene derivatives
WO1998015647A1 (en) * 1996-10-08 1998-04-16 Novartis Ag Modulation of apoptosis
JP4777489B2 (ja) * 1997-03-31 2011-09-21 ザ チルドレンズ メディカル センター コーポレーション アポトーシス性酵素を不活性化するためのニトロシル化
BR0011529A (pt) 1999-06-03 2002-12-17 Nippon Suisan Kaisha Ltd Compostos de heterociclos fundidos tricìclicos, processo para preparar os mesmos e uso destes
WO2003057204A2 (en) * 2002-01-08 2003-07-17 Nordic Bioscience A/S Modulation of iamt (pimt or pcmt) in immune system
EP1589963A1 (en) * 2003-01-29 2005-11-02 Novartis AG Use of 10-aminoaliphatyl-dibenz b,f oxepines for the tr eatment of degenerative ocular disorders
AU2004290499C1 (en) * 2003-11-03 2011-02-24 Probiodrug Ag Combinations useful for the treatment of neuronal disorders
US7906180B2 (en) * 2004-02-27 2011-03-15 Molecular Imprints, Inc. Composition for an etching mask comprising a silicon-containing material
EP1757284A1 (en) 2005-08-25 2007-02-28 Santhera Pharmaceuticals (Schweiz) AG Use of N-(dibenz(b,f)oxepin-10ylmethyl)-N-methyl-N-prop-2-ynylamine (omigapil) for the prophylaxis and/or treatment of muscular dystrophy
EP1842539A1 (en) 2006-04-05 2007-10-10 Santhera Pharmaceuticals (Schweiz) AG Use of N- (dibenz(b,f)oxepin-10-ylmethyl)N-methyl-N-prop-2-ynylamine (omigapil) for the prophylaxis and/or treatment of congenital muscular dystrophy or myopathy resulting from collagen VI deficiency
KR20110087582A (ko) 2010-01-26 2011-08-03 삼성전자주식회사 식각액 조성물 및 이를 이용한 식각 방법
WO2014120885A1 (en) 2013-01-30 2014-08-07 The Johns Hopkins University Treatment of drug abuse by preventing gapdh nitrosylation

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3100207A (en) * 1959-07-08 1963-08-06 Smith Kline French Lab 10-aminoalkylbenzo[b,f]thiepin and -dibenz[b,f]oxepin derivatives
NL124626C (pt) * 1964-06-29
DE1493782B1 (de) * 1964-06-29 1969-12-11 Geigy Ag J R Basisch substituierte Dibenzo[b,f]-oxepine und deren nicht-toxische Salze
CH440318A (de) * 1964-11-03 1967-07-31 Geigy Ag J R Verfahren zur Herstellung von neuen Thiepin- und Oxepinderivaten
US3641056A (en) * 1970-01-06 1972-02-08 Ciba Geigy Corp 10-(aminomethyl)- and (aminoethyl)-dibenz (b f)oxepins
US3928383A (en) * 1973-06-08 1975-12-23 Hoffmann La Roche Propynylamine-substituted dibenzo{8 b,f{9 thiepins and dibenz{8 b,f{9 oxepins
IE62754B1 (en) * 1988-08-26 1995-02-22 Akzo Nv Tetracyclic antidepressants

Also Published As

Publication number Publication date
HUP9600272A3 (en) 2000-03-28
HUP9600272A2 (en) 1997-05-28
GR3036656T3 (en) 2001-12-31
AU715245B2 (en) 2000-01-20
JPH08259559A (ja) 1996-10-08
US5780501A (en) 1998-07-14
AU4330796A (en) 1996-08-15
HU9600272D0 (en) 1996-04-29
BR9600339A (pt) 1998-01-27
FI120400B (fi) 2009-10-15
EP0726265B1 (de) 2001-07-25
FI960529A (fi) 1996-08-09
JP2005008646A (ja) 2005-01-13
KR100485538B1 (ko) 2005-09-02
US5780500A (en) 1998-07-14
JP3625559B2 (ja) 2005-03-02
IL117067A0 (en) 1996-06-18
ZA96960B (en) 1996-08-08
RU2160734C2 (ru) 2000-12-20
TW420672B (en) 2001-02-01
DE59607332D1 (de) 2001-08-30
DK0726265T3 (da) 2001-10-22
EP0726265A1 (de) 1996-08-14
ES2160790T3 (es) 2001-11-16
NZ280940A (en) 1997-12-19
NO960499L (no) 1996-08-09
ATE203528T1 (de) 2001-08-15
PT726265E (pt) 2001-12-28
NO314356B1 (no) 2003-03-10
CA2168937C (en) 2009-10-20
FI960529A0 (fi) 1996-02-05
CA2168937A1 (en) 1996-08-09
AR004474A1 (es) 1998-12-16
CN1216052C (zh) 2005-08-24
CY2333B1 (en) 2004-02-06
SA01220313A (ar) 2005-12-03
HU229227B1 (en) 2013-09-30
MX9600503A (es) 1997-01-31
KR960031452A (ko) 1996-09-17
CN1137039A (zh) 1996-12-04
NO960499D0 (no) 1996-02-07
MY113427A (en) 2002-02-28

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Legal Events

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FF Patent granted
KB Patent renewed
KB Patent renewed
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