[go: up one dir, main page]

IL116142A0 - Method of using triaryl-ethylene derivatives in the treatment and prevention of osteoporosis - Google Patents

Method of using triaryl-ethylene derivatives in the treatment and prevention of osteoporosis

Info

Publication number
IL116142A0
IL116142A0 IL11614295A IL11614295A IL116142A0 IL 116142 A0 IL116142 A0 IL 116142A0 IL 11614295 A IL11614295 A IL 11614295A IL 11614295 A IL11614295 A IL 11614295A IL 116142 A0 IL116142 A0 IL 116142A0
Authority
IL
Israel
Prior art keywords
triaryl
osteoporosis
prevention
treatment
ethylene derivatives
Prior art date
Application number
IL11614295A
Other languages
English (en)
Original Assignee
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/531,885 external-priority patent/US5691384A/en
Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc
Publication of IL116142A0 publication Critical patent/IL116142A0/xx
Priority to IL12943199A priority Critical patent/IL129431A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/136—Amines having aromatic rings, e.g. ketamine, nortriptyline having the amino group directly attached to the aromatic ring, e.g. benzeneamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4453—Non condensed piperidines, e.g. piperocaine only substituted in position 1, e.g. propipocaine, diperodon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL11614295A 1994-11-29 1995-11-27 Method of using triaryl-ethylene derivatives in the treatment and prevention of osteoporosis IL116142A0 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IL12943199A IL129431A0 (en) 1994-11-29 1999-04-13 Method of using triaryl-ethylene derivatives in the treatment and prevention of osteoporosis

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34611194A 1994-11-29 1994-11-29
US08/531,885 US5691384A (en) 1994-11-29 1995-10-11 Method of using triaryl-ethylene derivatives in the treatment and prevention of osteoporosis

Publications (1)

Publication Number Publication Date
IL116142A0 true IL116142A0 (en) 1996-01-31

Family

ID=26994698

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11614295A IL116142A0 (en) 1994-11-29 1995-11-27 Method of using triaryl-ethylene derivatives in the treatment and prevention of osteoporosis

Country Status (12)

Country Link
US (1) US5693674A (xx)
EP (1) EP0794771A1 (xx)
JP (1) JPH10509962A (xx)
CN (1) CN1167437A (xx)
AU (1) AU707290B2 (xx)
CA (1) CA2206422A1 (xx)
FI (1) FI972235A0 (xx)
HU (1) HUT77603A (xx)
IL (1) IL116142A0 (xx)
MX (1) MX9703944A (xx)
NO (1) NO972426L (xx)
WO (1) WO1996016646A1 (xx)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7005428B1 (en) 1998-06-11 2006-02-28 Endorecherche, Inc. Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors
US6465445B1 (en) 1998-06-11 2002-10-15 Endorecherche, Inc. Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors
TW593256B (en) 1999-11-16 2004-06-21 Hormos Medical Oy Ltd Triphenylalkene derivatives and their use as selective estrogen receptor modulators
US20040248989A1 (en) 2003-06-05 2004-12-09 Risto Santti Method for the treatment or prevention of lower urinary tract symptoms
MX2008014825A (es) * 2006-05-22 2008-12-01 Hormos Medical Ltd Moduladores selectivos del receptor de estrogeno o inhibidores de aromatasa para tratar prostatitis cronica no bacteriana.
WO2008099060A2 (en) * 2007-02-14 2008-08-21 Hormos Medical Ltd Methods for the preparation of fispemifene from ospemifene
WO2008099059A1 (en) * 2007-02-14 2008-08-21 Hormos Medical Ltd Method for the preparation of therapeutically valuable triphenylbutene derivatives
MX2010014372A (es) 2008-07-02 2011-06-20 British Columbia Cancer Agency Agentes terapeuticos derivados de eter diglicidico y métodos para su uso.
JP6174156B2 (ja) 2012-10-19 2017-08-02 フェルミオン オサケ ユキチュア オスペミフェンの製造方法
CA2973036A1 (en) * 2015-01-13 2016-07-21 British Columbia Cancer Agency Branch Heterocyclic compounds for cancer imaging and treatment and methods for their use
WO2016141458A1 (en) 2015-03-12 2016-09-15 British Columbia Cancer Agency Branch Bisphenol ether derivatives and methods for using the same
US20170298033A1 (en) 2016-04-15 2017-10-19 The University Of British Columbia Bisphenol derivatives and their use as androgen receptor activity modulators
US11485713B2 (en) 2018-05-25 2022-11-01 Essa Pharma, Inc. Androgen receptor modulators and methods for their use
CN113195441B (zh) 2018-10-18 2024-07-12 埃萨制药股份有限公司 雄激素受体调节剂及其使用方法
WO2020198712A1 (en) 2019-03-28 2020-10-01 Essa Pharma, Inc. Pharmaceutical compositions and combinations comprising inhibitors of the androgen receptor and uses thereof
WO2021212032A1 (en) 2020-04-17 2021-10-21 Essa Pharma, Inc. Solid forms of an n-terminal domain androgen receptor inhibitor and uses thereof

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2914563A (en) * 1957-08-06 1959-11-24 Wm S Merrell Co Therapeutic composition
GB1013907A (en) * 1962-09-13 1965-12-22 Ici Ltd Alkene derivatives
US3247252A (en) * 1962-11-14 1966-04-19 Richardson Merrell Inc Beta-dialkylaminoethylamino-triphenylethanols, -ethanes, and -ethenes
GB1099093A (en) * 1965-09-03 1968-01-17 Ici Ltd Alkene derivatives
GB1128379A (en) * 1966-06-20 1968-09-25 Ici Ltd Novel alkene derivatives, process for the preparation thereof and compositions containing the same
US4001229A (en) * 1974-04-04 1977-01-04 Mead Johnson & Company Alkanesulfonamido triphenylethylenes
EP0002097B1 (en) * 1977-08-22 1981-08-05 Imperial Chemical Industries Plc Triphenylalkene derivatives, process for their preparation and pharmaceutical compositions containing them
US4729999A (en) * 1984-10-12 1988-03-08 Bcm Technologies Antiestrogen therapy for symptoms of estrogen deficiency
US4970237A (en) * 1987-03-20 1990-11-13 Yale University Use of clomiphene to increase bone mass in premenopausal women
JPH06312930A (ja) * 1993-04-30 1994-11-08 Kuraray Co Ltd 骨粗鬆症治療剤
US5525633A (en) * 1993-09-24 1996-06-11 Merrell Dow Pharmaceuticals Inc. Triaryl-ethylene derivatives
ZA956029B (en) * 1994-07-22 1997-01-20 Lilly Co Eli Combination treatment for inhibiting bone loss

Also Published As

Publication number Publication date
NO972426D0 (no) 1997-05-28
HUT77603A (hu) 1998-06-29
AU4196796A (en) 1996-06-19
JPH10509962A (ja) 1998-09-29
WO1996016646A1 (en) 1996-06-06
CA2206422A1 (en) 1996-06-06
NO972426L (no) 1997-07-29
CN1167437A (zh) 1997-12-10
EP0794771A1 (en) 1997-09-17
FI972235L (fi) 1997-05-27
FI972235A0 (fi) 1997-05-27
AU707290B2 (en) 1999-07-08
US5693674A (en) 1997-12-02
MX9703944A (es) 1998-05-31

Similar Documents

Publication Publication Date Title
US5584086B1 (en) Therapeutic pillow and method
SG32522A1 (en) Surface treatment method and system
AP9300598A0 (en) Compositions and method for waste treatment
AU3552195A (en) Improved patient-transport and treatment apparatus
HU9401580D0 (en) Method for the preparation and popification of alphia - interferon
GB9422571D0 (en) Haemorrihoidal compositions and method of use
IL116142A0 (en) Method of using triaryl-ethylene derivatives in the treatment and prevention of osteoporosis
AU7301894A (en) Water treatment method and water treatment apparatus
HK1014563A1 (en) Method and apparatus for the surface treatment of parts
ZA931778B (en) Method and composition for the treatment of osteoporosis
IL120606A0 (en) Apparatus and method for the reduction of snoring
IL115224A0 (en) Preparations for use in the treatment of osteoporosis
GB2285441B (en) Method and device for the treatment of water
GB2310446B (en) Surface treatment apparatus and method
GB9408342D0 (en) Method and composition
IL129431A0 (en) Method of using triaryl-ethylene derivatives in the treatment and prevention of osteoporosis
ZA9510062B (en) Method of using triaryl-ethylene derivatives in the treatment and prevention of osteoporosis
PL331283A1 (en) Preparation for treating and/or preventing stupefaction
GB9408702D0 (en) Surgical apparatus and method
GB9415902D0 (en) Method of treatment
GB9414888D0 (en) Method and composition
GB9419087D0 (en) Method and composition
GB9407335D0 (en) Method of treatment
GB9414652D0 (en) Method of treatment
ZA947249B (en) Apparatus and method for the reduction of snoring