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IL114759A0 - Hydroxyalkylamine derivatives - Google Patents

Hydroxyalkylamine derivatives

Info

Publication number
IL114759A0
IL114759A0 IL11475995A IL11475995A IL114759A0 IL 114759 A0 IL114759 A0 IL 114759A0 IL 11475995 A IL11475995 A IL 11475995A IL 11475995 A IL11475995 A IL 11475995A IL 114759 A0 IL114759 A0 IL 114759A0
Authority
IL
Israel
Prior art keywords
hydroxyalkylamine
derivatives
hydroxyalkylamine derivatives
Prior art date
Application number
IL11475995A
Other versions
IL114759A (en
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9415330A external-priority patent/GB9415330D0/en
Priority claimed from GBGB9425599.9A external-priority patent/GB9425599D0/en
Priority claimed from GBGB9509923.0A external-priority patent/GB9509923D0/en
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Priority to IL12552595A priority Critical patent/IL125525A/en
Publication of IL114759A0 publication Critical patent/IL114759A0/en
Publication of IL114759A publication Critical patent/IL114759A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/74Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/58Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
IL11475995A 1994-07-29 1995-07-27 Benzoxazole derivatives and pharmaceutical compositions containing them IL114759A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IL12552595A IL125525A (en) 1994-07-29 1995-07-27 Hydroxyalkylamine derivatives

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB9415330A GB9415330D0 (en) 1994-07-29 1994-07-29 Novel compounds
GBGB9425599.9A GB9425599D0 (en) 1994-12-19 1994-12-19 Novel compounds
GBGB9509923.0A GB9509923D0 (en) 1995-05-17 1995-05-17 Novel compounds
PCT/GB1995/001323 WO1996004261A1 (en) 1994-07-29 1995-06-07 Benzoxazoles and pryridine derivatives useful in the treatment of the type ii diabetes

Publications (2)

Publication Number Publication Date
IL114759A0 true IL114759A0 (en) 1995-12-31
IL114759A IL114759A (en) 1999-10-28

Family

ID=27267309

Family Applications (3)

Application Number Title Priority Date Filing Date
IL12552595A IL125525A (en) 1994-07-29 1995-07-27 Hydroxyalkylamine derivatives
IL11475995A IL114759A (en) 1994-07-29 1995-07-27 Benzoxazole derivatives and pharmaceutical compositions containing them
IL12552598A IL125525A0 (en) 1994-07-29 1998-07-27 Hydroxyalkylamine derivatives

Family Applications Before (1)

Application Number Title Priority Date Filing Date
IL12552595A IL125525A (en) 1994-07-29 1995-07-27 Hydroxyalkylamine derivatives

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL12552598A IL125525A0 (en) 1994-07-29 1998-07-27 Hydroxyalkylamine derivatives

Country Status (16)

Country Link
EP (1) EP0772605A1 (en)
AP (1) AP776A (en)
BR (1) BR9508468A (en)
CA (1) CA2196079A1 (en)
CZ (1) CZ25497A3 (en)
DZ (1) DZ1916A1 (en)
FI (1) FI970357A (en)
HU (1) HUT76637A (en)
IL (3) IL125525A (en)
MA (1) MA23632A1 (en)
MX (1) MX9700763A (en)
NO (1) NO307827B1 (en)
OA (1) OA10470A (en)
PL (1) PL318766A1 (en)
SK (1) SK12297A3 (en)
WO (2) WO1996004261A1 (en)

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KR100517644B1 (en) * 1997-10-27 2005-09-28 닥터 레디스 레보러터리즈 리미티드 Novel tricyclic compounds and their use in medicine; process for their preparation and pharmaceutical compositions containing them
US6369067B1 (en) 1997-10-27 2002-04-09 Dr. Reddy's Research Foundation Monocyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them
US6444816B1 (en) 1997-10-27 2002-09-03 Dr. Reddy's Research Foundation Fused 7-oxo-pyrimidinyl compounds, preparation, composition and use thereof
WO1999019313A1 (en) * 1997-10-27 1999-04-22 Dr. Reddy's Research Foundation Novel tricyclic compounds and their use in medicine; process for their preparation and pharmaceutical compositions containing them
CA2307068C (en) 1997-10-27 2007-04-10 Dr. Reddy's Research Foundation Bicyclic compounds, process for their preparation and pharmaceutical compositions containing them
US6130214A (en) * 1997-10-27 2000-10-10 Dr. Reddy's Research Foundation Benzothiazin and benzoxazin derivatives; their preparation and uses
US6265401B1 (en) * 1997-10-27 2001-07-24 Reddy-Cheminor, Inc. Bicyclic compounds and their use in medicine, process for their preparation and pharmaceutical compositions containing them
US6440961B1 (en) 1997-10-27 2002-08-27 Dr. Reddy's Research Foundation Tricyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them
PL341795A1 (en) * 1998-05-27 2001-05-07 Reddy Research Foundation Bicycle compounds, process for obtaining them and pharmacological compositions containing such compounds
PL346660A1 (en) 1998-09-17 2002-02-25 Bristol Myers Squibb Co Method for treating atherosclerosis employing an ap2 inhibitor and combination
US6300339B1 (en) 1998-10-21 2001-10-09 Novo Nordisk A/S Compounds, their preparation and use
US6248781B1 (en) 1998-10-21 2001-06-19 Novo Nordisk A/S Compounds useful in the treatment of conditions mediated by peroxisome proliferator-activated receptors (PPAR)
AU6325899A (en) * 1998-10-21 2000-05-08 Dr. Reddy's Research Foundation New compounds, their preparation and use
US6214820B1 (en) 1998-10-21 2001-04-10 Novo Nordisk A/S Compounds, their preparation and use
WO2000023445A1 (en) * 1998-10-21 2000-04-27 Novo Nordisk A/S New compounds, their preparation and use
US6468996B1 (en) 1998-10-21 2002-10-22 Novo Nordisk A/S Substituted hetero-polycyclic compounds as PPARα and PPARγ activators
JP2002527520A (en) * 1998-10-21 2002-08-27 ノボ ノルディスク アクティーゼルスカブ New compounds, their production and use
JP2002527507A (en) * 1998-10-21 2002-08-27 ノボ ノルディスク アクティーゼルスカブ New compounds, their preparation and use
WO2000023415A1 (en) * 1998-10-21 2000-04-27 Novo Nordisk A/S New compounds, their preparation and use
EP1123268A1 (en) * 1998-10-21 2001-08-16 Novo Nordisk A/S New compounds, their preparation and use
US6365586B1 (en) 1998-10-21 2002-04-02 Novo Nordisk A/S Compounds, their preparation and use
UA60386C2 (en) * 1998-10-29 2003-10-15 Reddys Laboratories Ltd A process for preparation of 3-[4-[2-(phenoxazine-10-yl)methoxy]phenyl]propionic acid derivatives (variants) and intermediary compounds for preparation thereof
US6531596B1 (en) 1998-10-29 2003-03-11 Dr. Reddy's Laboratories Ltd. Process for the preparation of new antidiabetic agents
AU3957800A (en) * 1999-04-16 2000-11-02 Dr. Reddy's Research Foundation Crystalline r- guanidines, arginine or (l) -arginine (2(s)) -2- ethoxy -3-(4- (2-(10(h) -phenoxazin -10-yl)ethoxy}phenyl)propanoate
US6274608B1 (en) 1999-04-20 2001-08-14 Novo Nordisk A/S Compounds, their preparation and use
WO2000063209A1 (en) * 1999-04-20 2000-10-26 Novo Nordisk A/S New compounds, their preparation and use
US6972294B1 (en) 1999-04-20 2005-12-06 Novo Nordisk, A/S Compounds, their preparation and use
EP1171431A1 (en) * 1999-04-20 2002-01-16 Novo Nordisk A/S Compounds, their preparation and use
CN1348439A (en) * 1999-04-20 2002-05-08 诺沃挪第克公司 New compounds, their preparation and use
US7414128B2 (en) 1999-04-20 2008-08-19 Dr. Reddy's Laboratories, Limited Crystalline R-guanidines, Arginine or (L)-Arginine (2S)-2-Ethoxy-3-{4-[2-(10H -phenoxazin-10-yl)ethoxy]phenyl}propanoate
US6369055B1 (en) 1999-04-20 2002-04-09 Novo Nordisk A/S Compounds, their preparation and use
BR0010139A (en) 1999-04-28 2004-03-02 Reddy Research Foundation Substituted bicyclic heterocycles, preparation process and use as anti-obesity and hypocholesterolemic agents
DE60005973T2 (en) 1999-08-27 2004-05-13 Eli Lilly And Co., Indianapolis BIARYL-OXA (THIA) ZOL DERIVATIVES AND THEIR USE AS PPARS MODULATORS
SK287294B6 (en) * 2000-01-19 2010-05-07 Cadila Healthcare Ltd. Pyrrole compounds, process for preparation, pharmaceutical composition, use and intermediates
US6569901B2 (en) 2000-01-28 2003-05-27 Novo Nordisk A/S Alkynyl-substituted propionic acid derivatives, their preparation and use
JP2003520839A (en) * 2000-01-28 2003-07-08 ノボ ノルディスク アクティーゼルスカブ New compounds, their production and use
US6555577B1 (en) 2000-01-28 2003-04-29 Novo Nordisk A/S Compounds, their preparation and use
US6509374B2 (en) 2000-04-17 2003-01-21 Novo Nordisk A/S Compounds, their preparation and use
US6599899B2 (en) 2000-05-12 2003-07-29 Ortho-Mcneil Pharmaceutical, Inc. Benzoxazinones as peroxisome proliferator activated receptor gamma modulators and method of treatment
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WO2001087861A2 (en) * 2000-05-12 2001-11-22 Ortho-Mcneil Pharmaceutical, Inc. Methods of treatment using benzoxazinones as peroxisome proliferator activated receptor gamma modulators
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US6987123B2 (en) * 2001-07-26 2006-01-17 Cadila Healthcare Limited Heterocyclic compounds, their preparation, pharmaceutical compositions containing them and their use in medicine
US7067530B2 (en) 2001-07-30 2006-06-27 Novo Nordisk A/S Compounds, their preparation and use
US6869967B2 (en) 2001-07-30 2005-03-22 Novo Nordisk A/S Peroxisome proliferator-activated receptor (PPAR) active vinyl carboxylic acid derivatives
US7220877B2 (en) 2001-10-17 2007-05-22 Novo Nordisk A/S Compounds, their preparation and use
JP2005518408A (en) 2001-12-29 2005-06-23 ノボ ノルディスク アクティーゼルスカブ Combination use of GLP-1 compounds and other drugs to treat dyslipidemia
US7015345B2 (en) 2002-02-21 2006-03-21 Asahi Kasei Pharma Corporation Propionic acid derivatives
US7816385B2 (en) 2002-12-20 2010-10-19 High Point Pharmaceuticals, Llc Dimeric dicarboxylic acid derivatives, their preparation and use
US6653334B1 (en) 2002-12-27 2003-11-25 Kowa Co., Ltd. Benzoxazole compound and pharmaceutical composition containing the same
US20100274022A1 (en) * 2007-04-26 2010-10-28 Pharmafrontier Co., Ltd. G protein-coupled receptor inhibitor and pharmaceutical product
ME02392B (en) 2011-01-31 2016-09-20 Cadila Healthcare Ltd Treatment for lipodystrophy
IN2013MU01468A (en) 2013-04-22 2015-04-17 Cadila Healthcare Ltd
WO2014195967A2 (en) 2013-05-30 2014-12-11 Cadila Healthcare Limited A process for preparation of pyrroles having hypolipidemic hypocholesteremic activities
TW201513857A (en) 2013-07-05 2015-04-16 Cadila Healthcare Ltd Synergistic compositions
IN2013MU02470A (en) 2013-07-25 2015-06-26 Cadila Healthcare Ltd
WO2015033357A2 (en) 2013-09-06 2015-03-12 Cadila Healthcare Limited An improved process for the preparation of pyrrole derivatives
WO2017064635A2 (en) 2015-10-14 2017-04-20 Cadila Healthcare Limited Pyrrole compound, compositions and process for preparation thereof
EP3551180B1 (en) 2016-12-09 2021-09-29 Cadila Healthcare Limited Treatment for primary biliary cholangitis

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US5089514A (en) * 1990-06-14 1992-02-18 Pfizer Inc. 3-coxazolyl [phenyl, chromanyl or benzofuranyl]-2-hydroxypropionic acid derivatives and analogs as hypoglycemic agents
RU2134686C1 (en) * 1992-07-03 1999-08-20 Смитклайн Бичам П.Л.С. Heterocyclic compound or its tautomeric form and/or pharmaceutically acceptable salt and/or pharmaceutically acceptable solvate, pharmaceutical composition decreasing blood glucose level, method of treatment and/or prophylaxis of hypoglycemic patients

Also Published As

Publication number Publication date
AP776A (en) 1999-10-28
PL318766A1 (en) 1997-07-07
WO1996004260A1 (en) 1996-02-15
BR9508468A (en) 1997-11-25
WO1996004261A1 (en) 1996-02-15
SK12297A3 (en) 1997-08-06
FI970357A0 (en) 1997-01-28
IL125525A (en) 2000-02-29
MX9700763A (en) 1997-05-31
NO307827B1 (en) 2000-06-05
FI970357A (en) 1997-03-26
CA2196079A1 (en) 1996-02-15
OA10470A (en) 2002-04-08
DZ1916A1 (en) 2002-02-17
AP9700918A0 (en) 1997-01-31
EP0772605A1 (en) 1997-05-14
IL114759A (en) 1999-10-28
IL125525A0 (en) 1999-03-12
CZ25497A3 (en) 1997-09-17
NO970373D0 (en) 1997-01-28
NO970373L (en) 1997-03-18
HUT76637A (en) 1997-10-28
MA23632A1 (en) 1996-04-01

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