IL114179A - Interleukin-5 specific recombinant antibodies - Google Patents

Interleukin-5 specific recombinant antibodies

Info

Publication number: IL114179A
Authority: IL; Israel
Prior art keywords: interleukin; recombinant antibodies; specific recombinant; specific; heavy
Prior art date: 1994-06-17

Application number

IL11417995A

Other languages

English (en)

Other versions

IL114179A0 (en

Original Assignee

Celltech Therapeutics Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-06-17

Filing date

1995-06-15

Publication date

2001-08-26

1995-06-15 Application filed by Celltech Therapeutics Ltd filed Critical Celltech Therapeutics Ltd

1995-10-31 Publication of IL114179A0 publication Critical patent/IL114179A0/xx

2001-08-26 Publication of IL114179A publication Critical patent/IL114179A/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
Immunology (AREA)
Pulmonology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Diabetes (AREA)
Hematology (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

IL11417995A 1994-06-17 1995-06-15 Interleukin-5 specific recombinant antibodies IL114179A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB9412230A GB9412230D0 (en)	1994-06-17	1994-06-17	Interleukin-5 specific recombiant antibodies

Publications (2)

Publication Number	Publication Date
IL114179A0 IL114179A0 (en)	1995-10-31
IL114179A true IL114179A (en)	2001-08-26

Family

ID=10756925

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL11417995A IL114179A (en)	1994-06-17	1995-06-15	Interleukin-5 specific recombinant antibodies

Country Status (18)

Country	Link
US (3)	US5998586A (xx)
EP (1)	EP0765392B1 (xx)
JP (1)	JP3973682B2 (xx)
AT (1)	ATE264389T1 (xx)
AU (1)	AU694783B2 (xx)
CA (1)	CA2192543C (xx)
CZ (1)	CZ292295B6 (xx)
DE (1)	DE69532889T2 (xx)
ES (1)	ES2218546T3 (xx)
FI (1)	FI965032L (xx)
GB (1)	GB9412230D0 (xx)
HU (1)	HU221641B1 (xx)
IL (1)	IL114179A (xx)
NO (1)	NO964808L (xx)
NZ (1)	NZ287927A (xx)
SK (1)	SK282625B6 (xx)
WO (1)	WO1995035375A1 (xx)
ZA (1)	ZA954990B (xx)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
USRE39548E1 (en)	1994-06-17	2007-04-03	Celltech R&D Limited	Interleukin-5 specific recombinant antibodies
GB9412230D0 (en) *	1994-06-17	1994-08-10	Celltech Ltd	Interleukin-5 specific recombiant antibodies
US7399837B2 (en)	1995-12-22	2008-07-15	Smithkline Beecham Corporation	Recombinant IL-5 antagonists useful in treatment of IL-5 mediated disorders
US5693323A (en) *	1994-12-23	1997-12-02	Smithkline Beecham Corporation	Recombinant IL-5 antagonists useful in treatment of IL-5 mediated disorders
DK0800536T3 (da) *	1994-12-23	2007-04-02	Smithkline Beecham Corp	Rekombinante IL-5 antagonister, der er nyttige til behandling af IL-5-medierede lidelser
CA2370391A1 (en)	1999-04-23	2000-11-02	Pharmexa A/S	Method for down-regulating il5 activity
PE20080262A1 (es)	2006-05-25	2008-04-30	Glaxo Group Ltd	Anticuerpo humanizado contra interleuquina-18
BRPI0910854A2 (pt)	2008-03-28	2015-10-06	Glaxosmithkline Llc	métodos de tratamento
WO2010042562A2 (en)	2008-10-06	2010-04-15	Minerva Biotechnologies Corporation	Muc1* antibodies
US8822663B2 (en)	2010-08-06	2014-09-02	Moderna Therapeutics, Inc.	Engineered nucleic acids and methods of use thereof
CN104531671A (zh)	2010-10-01	2015-04-22	现代治疗公司	设计核酸及其使用方法
US9505826B2 (en) *	2010-12-22	2016-11-29	Teva Pharmaceuticals Australia Pty Ltd	Modified antibody with improved half-life
CA2831613A1 (en)	2011-03-31	2012-10-04	Moderna Therapeutics, Inc.	Delivery and formulation of engineered nucleic acids
US9464124B2 (en)	2011-09-12	2016-10-11	Moderna Therapeutics, Inc.	Engineered nucleic acids and methods of use thereof
BR112014007852B1 (pt)	2011-10-03	2021-11-03	Moderna Therapeutics, Inc	Polinucleotídeo isolado modificado e composição farmacêutica
AU2012352180A1 (en)	2011-12-16	2014-07-31	Moderna Therapeutics, Inc.	Modified nucleoside, nucleotide, and nucleic acid compositions
US9254311B2 (en)	2012-04-02	2016-02-09	Moderna Therapeutics, Inc.	Modified polynucleotides for the production of proteins
US9572897B2 (en)	2012-04-02	2017-02-21	Modernatx, Inc.	Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
WO2013151672A2 (en)	2012-04-02	2013-10-10	modeRNA Therapeutics	Modified polynucleotides for the production of oncology-related proteins and peptides
US9283287B2 (en)	2012-04-02	2016-03-15	Moderna Therapeutics, Inc.	Modified polynucleotides for the production of nuclear proteins
RS63237B1 (sr)	2012-11-26	2022-06-30	Modernatx Inc	Terminalno modifikovana rnk
RU2681994C2 (ru) *	2012-12-26	2019-03-14	Онкосинерджи, Инк.	КОМПОЗИЦИИ АНТИТЕЛА К ИНТЕГРИНУ β1 И СПОСОБЫ ИХ ПРИМЕНЕНИЯ
US8980864B2 (en)	2013-03-15	2015-03-17	Moderna Therapeutics, Inc.	Compositions and methods of altering cholesterol levels
US10023626B2 (en)	2013-09-30	2018-07-17	Modernatx, Inc.	Polynucleotides encoding immune modulating polypeptides
JP2016538829A (ja)	2013-10-03	2016-12-15	モデルナセラピューティクスインコーポレイテッドＭｏｄｅｒｎａＴｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ．	低密度リポタンパク質受容体をコードするポリヌクレオチド
CN106794194A (zh)	2014-06-30	2017-05-31	中央研究院	用于癌症治疗的介白素‑17受体b（il‑17rb）及其配体il‑17b之拮抗剂
AU2016219350A1 (en)	2015-02-10	2017-08-24	Minerva Biotechnologies Corporation	Humanized anti-MUC1* antibodies
EA037487B1 (ru)	2015-08-24	2021-04-02	Глэксосмитклайн Интеллекчуал Проперти (No.2) Лимитед	Биофармацевтические композиции
CN110913887A (zh)	2017-06-06	2020-03-24	葛兰素史克有限责任公司	用于儿科患者的生物药物组合物和方法
CN111065651B (zh)	2017-09-29	2023-07-14	江苏恒瑞医药股份有限公司	Il-5抗体、其抗原结合片段及医药用途
CN109942706A (zh) *	2017-12-21	2019-06-28	三生国健药业（上海）股份有限公司	结合人il-5的单克隆抗体、其制备方法和用途
WO2020119728A1 (zh) *	2018-12-12	2020-06-18	尚华科创投资管理（江苏）有限公司	抗人白细胞介素5(il-5)单克隆抗体及其应用
KR20210145187A (ko)	2019-03-29	2021-12-01	지앙수 헨그루이 메디슨 컴퍼니 리미티드	Il-5에 대한 항체를 함유하는 약학적 조성물 및 이의 용도

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8308235D0 (en) *	1983-03-25	1983-05-05	Celltech Ltd	Polypeptides
US4816567A (en) *	1983-04-08	1989-03-28	Genentech, Inc.	Recombinant immunoglobin preparations
GB8607679D0 (en) *	1986-03-27	1986-04-30	Winter G P	Recombinant dna product
EP0367596B1 (en) *	1988-11-03	1993-12-22	Schering Corporation	Antagonist to interleukin-5 for preventing or reducing eosinophilia
IL162181A (en) *	1988-12-28	2006-04-10	Pdl Biopharma Inc	A method of producing humanized immunoglubulin, and polynucleotides encoding the same
US5530101A (en) *	1988-12-28	1996-06-25	Protein Design Labs, Inc.	Humanized immunoglobulins
GB8928874D0 (en) *	1989-12-21	1990-02-28	Celltech Ltd	Humanised antibodies
AU8910891A (en) *	1990-11-20	1992-06-11	National Heart & Lung Institute, The	Treatment of lung diseases
HUT67943A (en) *	1992-02-06	1995-05-29	Schering Corp	Design, cloning and expression of humanized monoclonal antibodies against human interleukin-5
AU684041B2 (en) *	1992-02-19	1997-12-04	Schering Corporation	Cloning and expression of humanized monoclonal antibodies against human interleukin-4
GB9412230D0 (en) *	1994-06-17	1994-08-10	Celltech Ltd	Interleukin-5 specific recombiant antibodies

1994
- 1994-06-17 GB GB9412230A patent/GB9412230D0/en active Pending
1995
- 1995-06-06 US US08/470,139 patent/US5998586A/en not_active Ceased
- 1995-06-15 IL IL11417995A patent/IL114179A/xx not_active IP Right Cessation
- 1995-06-15 ZA ZA954990A patent/ZA954990B/xx unknown
- 1995-06-16 ES ES95921931T patent/ES2218546T3/es not_active Expired - Lifetime
- 1995-06-16 NZ NZ287927A patent/NZ287927A/en not_active IP Right Cessation
- 1995-06-16 WO PCT/GB1995/001411 patent/WO1995035375A1/en active IP Right Grant
- 1995-06-16 CA CA002192543A patent/CA2192543C/en not_active Expired - Lifetime
- 1995-06-16 DE DE69532889T patent/DE69532889T2/de not_active Expired - Lifetime
- 1995-06-16 HU HU9603183A patent/HU221641B1/hu not_active IP Right Cessation
- 1995-06-16 EP EP95921931A patent/EP0765392B1/en not_active Expired - Lifetime
- 1995-06-16 JP JP50181796A patent/JP3973682B2/ja not_active Expired - Lifetime
- 1995-06-16 AT AT95921931T patent/ATE264389T1/de not_active IP Right Cessation
- 1995-06-16 AU AU26803/95A patent/AU694783B2/en not_active Ceased
- 1995-06-16 SK SK1600-96A patent/SK282625B6/sk unknown
- 1995-06-16 CZ CZ19963712A patent/CZ292295B6/cs not_active IP Right Cessation
1996
- 1996-11-13 NO NO964808A patent/NO964808L/no unknown
- 1996-12-16 FI FI965032A patent/FI965032L/fi not_active Application Discontinuation
1999
- 1999-07-02 US US09/347,061 patent/US6316227B1/en not_active Expired - Lifetime
2001
- 2001-05-15 US US09/855,271 patent/US6734286B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
US5998586A (en)	1999-12-07
AU2680395A (en)	1996-01-15
US6316227B1 (en)	2001-11-13
DE69532889D1 (de)	2004-05-19
JPH10501697A (ja)	1998-02-17
NO964808D0 (no)	1996-11-13
CA2192543C (en)	2008-07-29
CA2192543A1 (en)	1995-12-28
GB9412230D0 (en)	1994-08-10
HU221641B1 (hu)	2002-12-28
HUT76672A (en)	1997-10-28
EP0765392B1 (en)	2004-04-14
IL114179A0 (en)	1995-10-31
SK160096A3 (en)	1997-06-04
CZ292295B6 (cs)	2003-08-13
JP3973682B2 (ja)	2007-09-12
AU694783B2 (en)	1998-07-30
WO1995035375A1 (en)	1995-12-28
US20020042089A1 (en)	2002-04-11
ZA954990B (en)	1996-12-17
HU9603183D0 (en)	1997-01-28
US6734286B2 (en)	2004-05-11
NO964808L (no)	1997-02-17
ES2218546T3 (es)	2004-11-16
FI965032A0 (fi)	1996-12-16
DE69532889T2 (de)	2005-03-10
NZ287927A (en)	1998-07-28
EP0765392A1 (en)	1997-04-02
ATE264389T1 (de)	2004-04-15
FI965032L (fi)	1996-12-16
CZ371296A3 (cs)	1998-05-13
SK282625B6 (sk)	2002-10-08

Publication	Publication Date	Title
HU9603183D0 (en)	1997-01-28	Interleukin-5 specific recombinant antibodies
FI956112A0 (fi)	1995-12-19	Monoklonaalinen anti- V-integriinivasta-aine
ES2106195T3 (es)	1997-11-01	Anticuerpo igg aglicosilado anti cd3.
AU8432498A (en)	1998-12-30	Human-cd28 specific monoclonal antibodies for antigen non-specific activation oft-lymphocytes
AU628948B2 (en)	1992-09-24	Monoclonal antibodies (mabs) against tumor-associated antigens, the preparation and use thereof
HUP9904620A3 (en)	2001-08-28	Purified sperm surface antigen,monoclonal antibody therefor and applications therefor
EP0578515A3 (en)	1995-05-10	Humanized monoclonal antibodies.
FI945865L (fi)	1995-02-08	Glykoprofeiini P:lle kohdistettuja monoklonaalisia vasta-aineita
AU6031090A (en)	1991-03-11	Monoclonal antibodies against a tumor-associated antigen
BR9509902A (pt)	1997-10-21	Fragmentos de anticorpos monoclonais apresentando atividade imunosupressante
EP0554458A4 (en)	1994-08-24	Immunoassay, monoclonal antibody and hybridoma
AU8547291A (en)	1992-03-30	Monoclonal antibodies against tenascin
EP0654532A4 (en)	1996-04-24	ANTIMUCOGLYCOPROTEIN MONOCLONAL ANTIBODIES.
AU5449390A (en)	1990-11-16	Monoclonal antibody against c-reactive protein
AU2652897A (en)	1997-12-05	Anti-human mp52 monoclonal antibody
AU2002300457A1 (en)	2003-02-13	Antibody fragment-polymer conjugates and humanized anti-IL-8 monoclonal antibodies
EP0668923A4 (en)	1996-06-26	MONOCLONAL ANTIBODY.
BR1100555B1 (pt)	2009-01-13	anticorpos monoclonais humanizados.
GB9212074D0 (en)	1992-07-22	Monoclonal antibody
AU4283793A (en)	1993-11-18	Monocyte adhesion protein and monoclonal antibody thereto
DK0778891T3 (da)	2005-02-21	Rekombinant monoklonalt antistof mod rhesus D (D7C2)
IE901210L (en)	1990-10-17	Monoclonal antibody
IE900922L (en)	1990-09-14	Monoclonal antibody
ZA954678B (en)	1995-12-08	Monoclonal antibody against cd44v6

Legal Events

Date	Code	Title
2002-02-10	KB	Patent renewed
2009-12-24	KB	Patent renewed
2013-06-27	KB	Patent renewed
2016-03-31	EXP	Patent expired