IL108856A - Hydroxymethyl furazancarboxylic acid derivatives, their preparation and pharmaceutical compositions containing them - Google Patents

Hydroxymethyl furazancarboxylic acid derivatives, their preparation and pharmaceutical compositions containing them

Info

Publication number: IL108856A
Authority: IL; Israel
Prior art keywords: alkyl; amino; once; cycloalkyl; phenyl
Prior art date: 1993-03-06

Application number

IL108856A

Other languages

English (en)

Other versions

IL108856A0 (en

Original Assignee

Cassella Farbwerke Mainkur Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-03-06

Filing date

1994-03-04

Publication date

1997-07-13

1994-03-04 Application filed by Cassella Farbwerke Mainkur Ag filed Critical Cassella Farbwerke Mainkur Ag

1994-06-24 Publication of IL108856A0 publication Critical patent/IL108856A0/xx

1997-07-13 Publication of IL108856A publication Critical patent/IL108856A/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/04—1,2,3-Oxadiazoles; Hydrogenated 1,2,3-oxadiazoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/08—1,2,5-Oxadiazoles; Hydrogenated 1,2,5-oxadiazoles

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Urology & Nephrology (AREA)
Reproductive Health (AREA)
Endocrinology (AREA)
Gynecology & Obstetrics (AREA)
Hematology (AREA)
Diabetes (AREA)
Vascular Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

IL108856A 1993-03-06 1994-03-04 Hydroxymethyl furazancarboxylic acid derivatives, their preparation and pharmaceutical compositions containing them IL108856A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE4307105A DE4307105A1 (de)	1993-03-06	1993-03-06	Hydroxymethylfurazancarbonsäurederivate

Publications (2)

Publication Number	Publication Date
IL108856A0 IL108856A0 (en)	1994-06-24
IL108856A true IL108856A (en)	1997-07-13

Family

ID=6482135

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL108856A IL108856A (en)	1993-03-06	1994-03-04	Hydroxymethyl furazancarboxylic acid derivatives, their preparation and pharmaceutical compositions containing them

Country Status (21)

Country	Link
US (1)	US5486531A (xx)
EP (1)	EP0687256B1 (xx)
JP (1)	JP3578456B2 (xx)
KR (1)	KR960701029A (xx)
CN (1)	CN1043140C (xx)
AT (1)	ATE157660T1 (xx)
AU (1)	AU676718B2 (xx)
CA (1)	CA2155840C (xx)
CZ (1)	CZ284264B6 (xx)
DE (2)	DE4307105A1 (xx)
DK (1)	DK0687256T3 (xx)
ES (1)	ES2108977T3 (xx)
FI (1)	FI954138L (xx)
GR (1)	GR3024928T3 (xx)
HU (1)	HUT72641A (xx)
IL (1)	IL108856A (xx)
PL (1)	PL177603B1 (xx)
RU (1)	RU2134687C1 (xx)
SK (1)	SK280354B6 (xx)
WO (1)	WO1994020478A1 (xx)
ZA (1)	ZA941533B (xx)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE4401150A1 (de) *	1994-01-17	1995-07-20	Cassella Ag	Furazancarbonsäurederivate
US6191131B1 (en)	1997-07-23	2001-02-20	Dupont Pharmaceuticals Company	Azolo triazines and pyrimidines
US6124289A (en) *	1996-07-24	2000-09-26	Dupont Pharmaceuticals Co.	Azolo triazines and pyrimidines
US6313124B1 (en)	1997-07-23	2001-11-06	Dupont Pharmaceuticals Company	Tetrazine bicyclic compounds
US7094782B1 (en)	1996-07-24	2006-08-22	Bristol-Myers Squibb Company	Azolo triazines and pyrimidines
US6060478A (en) *	1996-07-24	2000-05-09	Dupont Pharmaceuticals	Azolo triazines and pyrimidines
CN100434428C (zh) *	2003-05-23	2008-11-19	巴斯利尔药物股份公司	呋咱并苯并咪唑类化合物
US8822509B2 (en)	2006-12-29	2014-09-02	The University Of Queensland	Pain-relieving compositions and uses therefor
CN112125865B (zh) *	2020-09-30	2022-08-12	北京理工大学	氧化呋咱化合物的合成方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3012862A1 (de) *	1980-04-02	1981-10-08	Cassella Ag, 6000 Frankfurt	Substituierte 1,2,5-oxdiazol-2-oxide als pharmazeutische wirkstoffe, ihre verwendung und sie enthaltende arzneimittel
DE3047730A1 (de) *	1980-12-18	1982-07-15	Cassella Ag, 6000 Frankfurt	3,4-bis-substituierte 1,2,5-oxdiazol-2-oxide, verfahren zu ihrer herstellung, ihre verwendung und sie enthaltende pharmazeutische zubereitungen

1993
- 1993-03-06 DE DE4307105A patent/DE4307105A1/de not_active Withdrawn
1994
- 1994-02-18 CZ CZ952281A patent/CZ284264B6/cs not_active IP Right Cessation
- 1994-02-18 PL PL94310655A patent/PL177603B1/pl unknown
- 1994-02-18 JP JP51951094A patent/JP3578456B2/ja not_active Expired - Fee Related
- 1994-02-18 WO PCT/EP1994/000459 patent/WO1994020478A1/de active IP Right Grant
- 1994-02-18 EP EP94908337A patent/EP0687256B1/de not_active Expired - Lifetime
- 1994-02-18 AT AT94908337T patent/ATE157660T1/de not_active IP Right Cessation
- 1994-02-18 CA CA002155840A patent/CA2155840C/en not_active Expired - Fee Related
- 1994-02-18 DE DE59403966T patent/DE59403966D1/de not_active Expired - Lifetime
- 1994-02-18 DK DK94908337.2T patent/DK0687256T3/da active
- 1994-02-18 RU RU95118170A patent/RU2134687C1/ru active
- 1994-02-18 CN CN94191395A patent/CN1043140C/zh not_active Expired - Fee Related
- 1994-02-18 KR KR1019950703761A patent/KR960701029A/ko not_active Ceased
- 1994-02-18 AU AU61414/94A patent/AU676718B2/en not_active Ceased
- 1994-02-18 SK SK1110-95A patent/SK280354B6/sk unknown
- 1994-02-18 ES ES94908337T patent/ES2108977T3/es not_active Expired - Lifetime
- 1994-02-18 HU HU9502603A patent/HUT72641A/hu unknown
- 1994-03-04 ZA ZA941533A patent/ZA941533B/xx unknown
- 1994-03-04 IL IL108856A patent/IL108856A/xx active IP Right Grant
- 1994-03-07 US US08/207,280 patent/US5486531A/en not_active Expired - Lifetime
1995
- 1995-09-04 FI FI954138A patent/FI954138L/fi unknown
1997
- 1997-10-03 GR GR970402569T patent/GR3024928T3/el unknown

Also Published As

Publication number	Publication date
ATE157660T1 (de)	1997-09-15
GR3024928T3 (en)	1998-01-30
KR960701029A (ko)	1996-02-24
EP0687256B1 (de)	1997-09-03
CZ284264B6 (cs)	1998-10-14
HUT72641A (en)	1996-05-28
JP3578456B2 (ja)	2004-10-20
CA2155840A1 (en)	1994-09-15
AU6141494A (en)	1994-09-26
DE4307105A1 (de)	1994-09-08
SK110095A3 (en)	1996-01-10
DK0687256T3 (da)	1998-03-30
SK280354B6 (sk)	1999-12-10
DE59403966D1 (de)	1997-10-09
JPH08507299A (ja)	1996-08-06
CA2155840C (en)	2005-05-24
EP0687256A1 (de)	1995-12-20
CN1119013A (zh)	1996-03-20
FI954138A0 (fi)	1995-09-04
PL177603B1 (pl)	1999-12-31
IL108856A0 (en)	1994-06-24
WO1994020478A1 (de)	1994-09-15
CN1043140C (zh)	1999-04-28
HU9502603D0 (en)	1995-11-28
FI954138L (fi)	1995-09-04
RU2134687C1 (ru)	1999-08-20
AU676718B2 (en)	1997-03-20
US5486531A (en)	1996-01-23
ES2108977T3 (es)	1998-01-01
CZ228195A3 (en)	1995-12-13
ZA941533B (en)	1994-10-06
PL310655A1 (en)	1995-12-27

Publication	Publication Date	Title
GB9218322D0 (en)	1992-10-14	Therapeutic agents
GB9126260D0 (en)	1992-02-12	Therapeutic agents
DE69720965D1 (de)	2003-05-22	Chinazolinderivate und deren verwendung als vegf hemmer
TW369526B (en)	1999-09-11	Diazabicyclic neurokinin antagonists
TW358096B (en)	1999-05-11	Pyrazolopyridimidinone antianginal agents
IL108856A (en)	1997-07-13	Hydroxymethyl furazancarboxylic acid derivatives, their preparation and pharmaceutical compositions containing them
IL102383A0 (en)	1993-01-14	Methylene-oxindole derivatives,their preparation and pharmaceutical compositions containing them
MY117803A (en)	2004-08-30	Monocyclic benzamides of 3- or 4-substituted 4-(aminomethyl)-piperidine derivatives
WO1994022829A3 (en)	1995-01-05	Dihydropyridines and new uses thereof
HUT60733A (en)	1992-10-28	Process for producing new n-(4-piperidinyl)-(dihydrobenzofuran or dihydro-2h-benzopyran)-carboxamide derivatives and pharmaceutical compositions comprising such compounds
ES8404330A1 (es)	1984-05-01	Un metodo para la produccion de derivados de esteres de acidos 1,4-dihidropiridin-3,5-dicarboxilicos.
MY119623A (en)	2005-06-30	Quinoline and quinazoline compounds useful in therapy, particularly in the treatment of benign prostatic hyperplasia
AU2190895A (en)	1995-10-09	Amidino derivatives useful as nitric oxide synthase inhibitors
HUT60271A (en)	1992-08-28	Process for producing tricyclic compounds, functioning as enzyme inhibitior and comprising amino or nitro group and pharmaceutical compositions comprising same as active ingredient
SE9701304D0 (sv)	1997-04-09	Compounds
GEP19960657B (en)	1996-12-24	Oxadiazole-alkyl-purine derivatives useful as antitussive agents
MY129176A (en)	2007-03-30	Tetrahydro gamma-carbolines
AU1065592A (en)	1992-08-13	Use of 4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine derivatives as free radical scavengers
BR9307091A (pt)	1999-03-30	Acido benzenoalcanóicos para doenças cardiovasculares
ATE42747T1 (de)	1989-05-15	N-(2-(tetrahydro-3,5-dioxo-1h-pyrrolizin-7a(5h) yl)ethyl>aminderivate.
DE69503905D1 (de)	1998-09-10	Peptidderivate mit metallopeptidasehemmender aktivität
NZ505110A (en)	2003-01-31	Neuroprotective agents
NO954764L (no)	1996-01-25	Psoralen-derivater, deres fremstilling og anvendelse
ES8103086A1 (es)	1981-02-16	Procedimiento de preparacion de nuevos derivados pirido (2,3-e)-as-triazinos y de sus sales de adicion acidas
CA2186224A1 (en)	1995-09-28	Amidino derivatives useful as nitric oxide synthase inhibitors

Legal Events

Date	Code	Title
1998-02-08	FF	Patent granted
1998-04-05	KB	Patent renewed
2000-08-13	KB	Patent renewed