IL102170A0 - Production and recovery of recombinant neurotrophins - Google Patents

Production and recovery of recombinant neurotrophins

Info

Publication number: IL102170A0
Authority: IL; Israel
Prior art keywords: recovery; production; recombinant neurotrophins; neurotrophins; recombinant
Prior art date: 1991-06-12

Application number

IL102170A

Original Assignee

Regeneron Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-06-12

Filing date

1992-06-11

Publication date

1993-01-14

1991-11-21 Priority claimed from US07/796,106 external-priority patent/US5389529A/en

1992-06-11 Application filed by Regeneron Pharma filed Critical Regeneron Pharma

1993-01-14 Publication of IL102170A0 publication Critical patent/IL102170A0/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
- C07K14/245—Escherichia (G)
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Genetics & Genomics (AREA)
Zoology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicinal Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biomedical Technology (AREA)
Biotechnology (AREA)
General Engineering & Computer Science (AREA)
Gastroenterology & Hepatology (AREA)
Wood Science & Technology (AREA)
Microbiology (AREA)
Physics & Mathematics (AREA)
Plant Pathology (AREA)
Toxicology (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

IL102170A 1991-06-12 1992-06-11 Production and recovery of recombinant neurotrophins IL102170A0 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US71518591A	1991-06-12	1991-06-12
US07/796,106 US5389529A (en)	1991-06-12	1991-11-21	Modified lamβ signal sequence and processes for producing recombinant neurotrophins

Publications (1)

Publication Number	Publication Date
IL102170A0 true IL102170A0 (en)	1993-01-14

Family

ID=27109290

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL102170A IL102170A0 (en)	1991-06-12	1992-06-11	Production and recovery of recombinant neurotrophins

Country Status (9)

Country	Link
EP (1)	EP0590059A4 (en)
JP (1)	JPH06508036A (en)
AU (1)	AU2238792A (en)
CA (1)	CA2111110A1 (en)
IE (1)	IE921888A1 (en)
IL (1)	IL102170A0 (en)
NZ (1)	NZ243084A (en)
PT (1)	PT100580A (en)
WO (1)	WO1992022665A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5169764A (en) *	1990-08-08	1992-12-08	Regeneron Pharmaceuticals, Inc.	Multitrophic and multifunctional chimeric neurotrophic factors, and nucleic acids and plasmids encoding the chimeras
AU654302B2 (en) *	1990-09-25	1994-11-03	Genentech Inc.	Novel neurothrophic factor
AU1254295A (en) *	1993-12-17	1995-07-03	Perkin-Elmer Corporation, The	Uncharged polymers for separation of biomolecules by capillary electrophoresis
US6472585B1 (en)	1994-04-25	2002-10-29	Genentech, Inc.	Cardiotrophin-1 defective mouse
CA2188017C (en) *	1994-04-25	2010-09-28	Joffre Baker	Cardiotrophin and uses therefor
US5534615A (en) *	1994-04-25	1996-07-09	Genentech, Inc.	Cardiac hypertrophy factor and uses therefor
US7258983B2 (en)	1994-04-25	2007-08-21	Genentech, Inc.	Cardiotrophin-1 compositions and methods for the treatment of tumor
FR2729972B1 (en) *	1995-01-31	1997-04-18	Sanofi Sa	PROCESS FOR THE EXTRACTION OF PERIPLASMIC PROTEINS FROM PROKARYOTIC MICROORGANISMS IN THE PRESENCE OF ARGININ
EP0942930B1 (en) *	1996-11-15	2007-08-29	Genentech, Inc.	Purification of neurotrophins
DE19944870A1 (en) *	1999-09-18	2001-03-29	Aventis Pharma Gmbh	Signal sequences for the production of Leu-hirudin via secretion by E. coli in the culture medium

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4511502A (en) *	1982-12-22	1985-04-16	Genentech, Inc.	Purification and activity assurance of precipitated heterologous proteins
DK161152C (en) *	1983-03-03	1991-11-11	Genentech Inc	POLYPEPTIDE OF PROPERTIES AS HUMAN BETA-NERVE GROWTH FACTOR AND METHOD FOR PREPARATION THEREOF, DNA ISOLAT comprising a sequence encoding the polypeptide is replicable expression vector for DNA SEQUENCE recombinant host cell transformed with the vector, pharmaceutical composition comprising the polypeptide and be stated in. THAT INCLUDES THE APPLICATION OF THE POLYPEPTID IN FORCE. OF A PHARMACEUTICAL PREPARATION
EP0448605A4 (en) *	1988-12-15	1991-11-21	Invitron Corporation	Use of basic amino acids to solubilize immunoglobulins
US5235043A (en) *	1990-04-06	1993-08-10	Synergen, Inc.	Production of biologically active, recombinant members of the ngf/bdnf family of neurotrophic proteins
AU654302B2 (en) *	1990-09-25	1994-11-03	Genentech Inc.	Novel neurothrophic factor

1992
- 1992-06-09 PT PT100580A patent/PT100580A/en not_active Application Discontinuation
- 1992-06-09 NZ NZ243084A patent/NZ243084A/en not_active IP Right Cessation
- 1992-06-11 JP JP5501050A patent/JPH06508036A/en active Pending
- 1992-06-11 IL IL102170A patent/IL102170A0/en unknown
- 1992-06-11 CA CA002111110A patent/CA2111110A1/en not_active Abandoned
- 1992-06-11 AU AU22387/92A patent/AU2238792A/en not_active Abandoned
- 1992-06-11 EP EP92914222A patent/EP0590059A4/en not_active Withdrawn
- 1992-06-11 WO PCT/US1992/005006 patent/WO1992022665A1/en not_active Application Discontinuation
- 1992-07-01 IE IE188892A patent/IE921888A1/en not_active Application Discontinuation

Also Published As

Publication number	Publication date
AU2238792A (en)	1993-01-12
PT100580A (en)	1993-09-30
WO1992022665A1 (en)	1992-12-23
EP0590059A4 (en)	1995-09-06
JPH06508036A (en)	1994-09-14
EP0590059A1 (en)	1994-04-06
NZ243084A (en)	1995-08-28
CA2111110A1 (en)	1992-12-23
IE921888A1 (en)	1992-12-16

Publication	Publication Date	Title
ZA924313B (en)	1993-03-31	Production and recovery of recombinant neurotrophins
IL101454A0 (en)	1992-12-30	Hybrid polypeptide and its production
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EP0469520A3 (en)	1992-10-07	Polyactide preparation and purification
IL90489A0 (en)	1990-01-18	Recombinant coccidiosis vaccines and their preparation
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IL102170A0 (en)	1993-01-14	Production and recovery of recombinant neurotrophins
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GB9104381D0 (en)	1991-04-17	Fabric and structure
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SG49830A1 (en)	1998-06-15	Vaccine design and production
GB9104596D0 (en)	1991-04-17	Production of recombinant proteins
ZA898929B (en)	1990-11-28	Tetramethyl-piperidyl terminated triazine oligomeric esters and amides
ZA929418B (en)	1993-06-07	Recombinant vaccines and method of producing same.
IL106166A0 (en)	1993-10-20	Process for the production and recovery of halonitroalkanes
GB9118721D0 (en)	1991-10-16	Production of fine points
GB2273709B (en)	1994-09-28	Peptide fragments of HIV
GB9104706D0 (en)	1991-04-17	Production of rivet-nuts