IE36822B1 - Process for the preparation of methylcobalamine - Google Patents

Process for the preparation of methylcobalamine

Info

Publication number: IE36822B1
Authority: IE; Ireland
Prior art keywords: methylcobalamine; nov; preparation; monomethyl; opochimie
Prior art date: 1971-11-10

Application number

IE1494/72A

Other languages

English (en)

Other versions

IE36822L (en

Original Assignee

Opochimie L

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1971-11-10

Filing date

1972-11-02

Publication date

1977-03-02

1972-11-02 Application filed by Opochimie L filed Critical Opochimie L

1973-05-10 Publication of IE36822L publication Critical patent/IE36822L/xx

1977-03-02 Publication of IE36822B1 publication Critical patent/IE36822B1/xx

Links

CPKISUMKCULUNR-UHFFFAOYSA-N 2-methoxy-2-oxoacetic acid Chemical compound COC(=O)C(O)=O CPKISUMKCULUNR-UHFFFAOYSA-N 0.000 abstract 1
OFOBLEOULBTSOW-UHFFFAOYSA-N Malonic acid Chemical compound OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 abstract 1
HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 abstract 1
230000001476 alcoholic effect Effects 0.000 abstract 1
150000001868 cobalt Chemical class 0.000 abstract 1
YOZNUFWCRFCGIH-BYFNXCQMSA-L hydroxocobalamin Chemical compound O[Co+]N([C@]1([H])[C@H](CC(N)=O)[C@]\2(CCC(=O)NC[C@H](C)OP(O)(=O)OC3[C@H]([C@H](O[C@@H]3CO)N3C4=CC(C)=C(C)C=C4N=C3)O)C)C/2=C(C)\C([C@H](C/2(C)C)CCC(N)=O)=N\C\2=C\C([C@H]([C@@]/2(CC(N)=O)C)CCC(N)=O)=N\C\2=C(C)/C2=N[C@]1(C)[C@@](C)(CC(N)=O)[C@@H]2CCC(N)=O YOZNUFWCRFCGIH-BYFNXCQMSA-L 0.000 abstract 1
235000004867 hydroxocobalamin Nutrition 0.000 abstract 1
239000011704 hydroxocobalamin Substances 0.000 abstract 1
239000002184 metal Substances 0.000 abstract 1
229910052751 metal Inorganic materials 0.000 abstract 1
230000011987 methylation Effects 0.000 abstract 1
238000007069 methylation reaction Methods 0.000 abstract 1
-1 monomethyl ester Chemical class 0.000 abstract 1
239000000843 powder Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H23/00—Compounds containing boron, silicon or a metal, e.g. chelates or vitamin B12

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Saccharide Compounds (AREA)
Catalysts (AREA)

IE1494/72A 1971-11-10 1972-11-02 Process for the preparation of methylcobalamine IE36822B1 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR7140233A FR2159720A5 (nl)	1971-11-10	1971-11-10

Publications (2)

Publication Number	Publication Date
IE36822L IE36822L (en)	1973-05-10
IE36822B1 true IE36822B1 (en)	1977-03-02

Family

ID=9085580

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IE1494/72A IE36822B1 (en)	1971-11-10	1972-11-02	Process for the preparation of methylcobalamine

Country Status (21)

Country	Link
JP (1)	JPS51120B2 (nl)
AR (1)	AR192677A1 (nl)
AT (1)	AT330374B (nl)
AU (1)	AU464986B2 (nl)
BE (1)	BE789252A (nl)
BR (1)	BR7207834D0 (nl)
CA (1)	CA972746A (nl)
CH (1)	CH545299A (nl)
DE (1)	DE2255203A1 (nl)
DK (1)	DK133381B (nl)
ES (1)	ES408279A1 (nl)
FR (1)	FR2159720A5 (nl)
GB (1)	GB1355899A (nl)
IE (1)	IE36822B1 (nl)
IL (1)	IL40762A (nl)
LU (1)	LU66165A1 (nl)
NL (1)	NL153548B (nl)
NO (1)	NO137095C (nl)
OA (1)	OA04191A (nl)
SE (1)	SE383350B (nl)
ZA (1)	ZA727831B (nl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NO742545L (nl) *	1973-08-08	1975-03-10	Opochimie L
JPS583753Y2 (ja) *	1978-08-25	1983-01-22	日立造船株式会社	海上構造物の接続装置
JPH0422432A (ja) *	1990-05-18	1992-01-27	Maruyama Mfg Co Ltd	散布液タンクにおける散布液攪拌方法及び装置
CA2394155C (en)	1999-12-09	2008-01-15	Eisai Co., Ltd.	Process for producing methylcobalamin
KR100876447B1 (ko)	2001-06-05	2008-12-29	에자이 알앤드디 매니지먼트 가부시키가이샤	메틸코발라민의 제조 방법

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1178073B (de) *	1961-06-09	1964-09-17	Merck Ag E	Verfahren zur Herstellung von Vitamin B und dessen stabilen Loesungen
FR1450375A (fr) *	1961-12-11	1966-06-24	Glaxo Group Ltd	Procédé de préparation d'un co-enzyme de vitamine b12 et d'analogues de celui-ci
DE1213842B (de) *	1962-04-27	1966-04-07	Hoffmann La Roche	Verfahren zur Herstellung von Co-R-Cobamiden

0
- BE BE789252D patent/BE789252A/xx unknown
1971
- 1971-11-10 FR FR7140233A patent/FR2159720A5/fr not_active Expired
1972
- 1972-09-25 DK DK472172AA patent/DK133381B/da unknown
- 1972-09-26 NO NO3443/72A patent/NO137095C/no unknown
- 1972-09-26 LU LU66165A patent/LU66165A1/xx unknown
- 1972-10-03 OA OA54710A patent/OA04191A/xx unknown
- 1972-10-24 NL NL727214368A patent/NL153548B/nl unknown
- 1972-11-01 SE SE7214155A patent/SE383350B/xx unknown
- 1972-11-01 GB GB5032472A patent/GB1355899A/en not_active Expired
- 1972-11-02 CA CA155,413A patent/CA972746A/en not_active Expired
- 1972-11-02 IE IE1494/72A patent/IE36822B1/xx unknown
- 1972-11-03 ZA ZA727831A patent/ZA727831B/xx unknown
- 1972-11-04 ES ES408279A patent/ES408279A1/es not_active Expired
- 1972-11-07 AU AU48582/72A patent/AU464986B2/en not_active Expired
- 1972-11-07 IL IL40762A patent/IL40762A/xx unknown
- 1972-11-07 AT AT945672A patent/AT330374B/de not_active IP Right Cessation
- 1972-11-08 CH CH1627072A patent/CH545299A/fr not_active IP Right Cessation
- 1972-11-08 BR BR7834/72A patent/BR7207834D0/pt unknown
- 1972-11-09 JP JP47111724A patent/JPS51120B2/ja not_active Expired
- 1972-11-09 AR AR245050A patent/AR192677A1/es active
- 1972-11-10 DE DE2255203A patent/DE2255203A1/de active Pending

Also Published As

Publication number	Publication date
IE36822L (en)	1973-05-10
NL7214368A (nl)	1973-05-14
ZA727831B (en)	1973-07-25
DK133381C (nl)	1976-10-04
FR2159720A5 (nl)	1973-06-22
AU464986B2 (en)	1975-09-11
LU66165A1 (nl)	1974-04-02
CH545299A (fr)	1973-12-15
AR192677A1 (es)	1973-02-28
ATA945672A (de)	1975-09-15
IL40762A0 (en)	1973-01-30
AU4858272A (en)	1974-05-09
SE383350B (sv)	1976-03-08
DE2255203A1 (de)	1973-05-17
JPS4947399A (nl)	1974-05-08
CA972746A (en)	1975-08-12
JPS51120B2 (nl)	1976-01-05
NO137095B (no)	1977-09-19
BR7207834D0 (pt)	1973-09-20
AT330374B (de)	1976-06-25
BE789252A (fr)	1973-03-26
ES408279A1 (es)	1975-11-01
NO137095C (no)	1977-12-28
DK133381B (da)	1976-05-10
IL40762A (en)	1975-07-28
GB1355899A (en)	1974-06-05
NL153548B (nl)	1977-06-15
OA04191A (fr)	1979-12-31

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