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HUP9900919A2 - 2,5-D-Mannóz-csoportot tartalmazó B antigén csoportba tartozó II és III típusú streptococcus poliszacharid-fragmentumok és ezeket tartalmazó vakcinakonjugátumok - Google Patents

2,5-D-Mannóz-csoportot tartalmazó B antigén csoportba tartozó II és III típusú streptococcus poliszacharid-fragmentumok és ezeket tartalmazó vakcinakonjugátumok

Info

Publication number
HUP9900919A2
HUP9900919A2 HU9900919A HUP9900919A HUP9900919A2 HU P9900919 A2 HUP9900919 A2 HU P9900919A2 HU 9900919 A HU9900919 A HU 9900919A HU P9900919 A HUP9900919 A HU P9900919A HU P9900919 A2 HUP9900919 A2 HU P9900919A2
Authority
HU
Hungary
Prior art keywords
type
framments
anhydro
terminal structure
conjugate vaccine
Prior art date
Application number
HU9900919A
Other languages
English (en)
Inventor
Catherine Dong
Francis Michon
Joseph Y. Tai
Original Assignee
North American Vaccine, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by North American Vaccine, Inc. filed Critical North American Vaccine, Inc.
Publication of HUP9900919A2 publication Critical patent/HUP9900919A2/hu
Publication of HUP9900919A3 publication Critical patent/HUP9900919A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092—Streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/08—Clostridium, e.g. Clostridium tetani
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/085—Staphylococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/646—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/831—Drug, bio-affecting and body treating compositions involving capsular polysaccharide of bacterium, e.g. polyribosyl ribitol phosphate

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Surgical Instruments (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Eljárás B csőpőrtba tartőzó II és III típűsú streptőcőccűsdepőlimerizálására, mellyel fehérje megkötésére alkalmas redűkálóvégettartalmazó pőliszacharid fragmensek állíthatók elő. A találmánykiterjed az ilyen fragmenseket tartalmazó mőlekűlakőnjűgátűmőkra ésvakcinákra, tővábbá ezek alkalmazására emlősök és az emberimműnizálására. ŕ
HU9900919A 1995-06-07 1996-06-06 Antigenic group b streptococcus type ii and type iii polysaccharide framments having a 2,5-anhydro-d-mannose terminal structure and conjugate vaccine thereof HUP9900919A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/481,883 US6284884B1 (en) 1995-06-07 1995-06-07 Antigenic group B streptococcus type II and type III polysaccharide fragments having a 2,5-anhydro-D-mannose terminal structure and conjugate vaccine thereof

Publications (2)

Publication Number Publication Date
HUP9900919A2 true HUP9900919A2 (hu) 1999-06-28
HUP9900919A3 HUP9900919A3 (en) 2000-04-28

Family

ID=23913768

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9900919A HUP9900919A3 (en) 1995-06-07 1996-06-06 Antigenic group b streptococcus type ii and type iii polysaccharide framments having a 2,5-anhydro-d-mannose terminal structure and conjugate vaccine thereof

Country Status (15)

Country Link
US (3) US6284884B1 (hu)
EP (1) EP0830380B1 (hu)
JP (1) JP4001625B2 (hu)
KR (1) KR100431236B1 (hu)
AT (1) ATE236194T1 (hu)
AU (1) AU706479B2 (hu)
CA (1) CA2223080C (hu)
DE (1) DE69627149T2 (hu)
ES (1) ES2200067T3 (hu)
HU (1) HUP9900919A3 (hu)
IL (3) IL136125A (hu)
NO (1) NO975546L (hu)
PL (1) PL187822B1 (hu)
WO (1) WO1996040795A1 (hu)
ZA (1) ZA964822B (hu)

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GB201121301D0 (en) 2011-12-12 2012-01-25 Novartis Ag Method
RU2015106791A (ru) 2012-10-03 2016-11-20 Глэксосмитиклайн Байолоджикалз Са Иммуногенные композиции
JP6434958B2 (ja) 2013-03-12 2018-12-05 ウェルスタット ヴァクシーンズ， エルエルシーＷｅｌｌｓｔａｔ Ｖａｃｃｉｎｅｓ， Ｌｌｃ 真菌の細胞壁多糖成分を標的とする抗体
CA2918076A1 (en) 2013-07-11 2015-01-15 Novartis Ag Site-specific chemoenzymatic protein modifications
US11612664B2 (en) 2016-04-05 2023-03-28 Gsk Vaccines S.R.L. Immunogenic compositions
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WO2023111826A1 (en) 2021-12-14 2023-06-22 Glaxosmithkline Biologicals Sa Bacterial immunization using qbeta hairpin nanoparticle constructs

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Also Published As

Publication number Publication date
IL118603A0 (en) 1996-10-16
ES2200067T3 (es) 2004-03-01
NO975546D0 (no) 1997-12-02
DE69627149D1 (de) 2003-05-08
JPH11507964A (ja) 1999-07-13
JP4001625B2 (ja) 2007-10-31
AU6095396A (en) 1996-12-30
EP0830380A1 (en) 1998-03-25
ATE236194T1 (de) 2003-04-15
US6284884B1 (en) 2001-09-04
AU706479B2 (en) 1999-06-17
US6602508B2 (en) 2003-08-05
EP0830380B1 (en) 2003-04-02
IL118603A (en) 2000-12-06
IL136125A0 (en) 2001-05-20
IL136125A (en) 2006-08-01
NO975546L (no) 1998-02-06
DE69627149T2 (de) 2003-12-04
ZA964822B (en) 1997-01-07
HUP9900919A3 (en) 2000-04-28
PL323822A1 (en) 1998-04-27
US6372222B1 (en) 2002-04-16
PL187822B1 (pl) 2004-10-29
CA2223080A1 (en) 1996-12-19
CA2223080C (en) 2007-03-20
KR100431236B1 (ko) 2004-09-16
KR19990022747A (ko) 1999-03-25
US20020031526A1 (en) 2002-03-14
WO1996040795A1 (en) 1996-12-19

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