HUP1600376A2 - A production method and a new crystalline from of an intermediate of synthesis of ticagrelor - Google Patents
A production method and a new crystalline from of an intermediate of synthesis of ticagrelorInfo
- Publication number
- HUP1600376A2 HUP1600376A2 HU1600376A HUP1600376A HUP1600376A2 HU P1600376 A2 HUP1600376 A2 HU P1600376A2 HU 1600376 A HU1600376 A HU 1600376A HU P1600376 A HUP1600376 A HU P1600376A HU P1600376 A2 HUP1600376 A2 HU P1600376A2
- Authority
- HU
- Hungary
- Prior art keywords
- ticagrelor
- synthesis
- production method
- new crystalline
- crystalline
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CZ2013-866A CZ2013866A3 (en) | 2013-11-08 | 2013-11-08 | Novel crystalline form of ticagrelor synthesis intermediate and process for preparing thereof |
PCT/CZ2014/000131 WO2015067230A1 (en) | 2013-11-08 | 2014-11-07 | A production method and a new crystalline form of an intermediate of synthesis of ticagrelor |
Publications (1)
Publication Number | Publication Date |
---|---|
HUP1600376A2 true HUP1600376A2 (en) | 2016-08-29 |
Family
ID=52117822
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU1600376A HUP1600376A2 (en) | 2013-11-08 | 2014-11-07 | A production method and a new crystalline from of an intermediate of synthesis of ticagrelor |
Country Status (4)
Country | Link |
---|---|
CN (1) | CN105940003A (en) |
CZ (1) | CZ2013866A3 (en) |
HU (1) | HUP1600376A2 (en) |
WO (1) | WO2015067230A1 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106946885A (en) * | 2016-01-07 | 2017-07-14 | 南京济群医药科技股份有限公司 | A kind of preparation method of ticagrelor monocrystalline |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI229674B (en) | 1998-12-04 | 2005-03-21 | Astra Pharma Prod | Novel triazolo[4,5-d]pyrimidine compounds, pharmaceutical composition containing the same, their process for preparation and uses |
GB0013407D0 (en) | 2000-06-02 | 2000-07-26 | Astrazeneca Ab | Forms of a chemical compound |
GB0013488D0 (en) | 2000-06-02 | 2000-07-26 | Astrazeneca Ab | Chemical compound |
TWI482772B (en) | 2006-08-21 | 2015-05-01 | Astrazeneca Ab | Compositions, suitable for oral administration, comprising a triazolo(4,5-d)pyrimidin derivate |
WO2008024044A1 (en) | 2006-08-21 | 2008-02-28 | Astrazeneca Ab | Compositions, suitable for oral administration, comprising a triazolo [4, 5] pyrimidin derivate |
CN102770434A (en) | 2009-12-03 | 2012-11-07 | 阿斯利康(瑞典)有限公司 | Co - crystals of a triazolo [4,5 - d] pyrimidine platelet aggregation inhibitor |
EP2633857B1 (en) | 2009-12-23 | 2015-08-12 | ratiopharm GmbH | Solid pharmaceutical dosage form of ticagrelor and acetylsalicylic acid |
US9056838B2 (en) * | 2011-04-06 | 2015-06-16 | Teva Pharmaceutical Industries Ltd. | Intermediates and processes for preparing Ticagrelor |
IN2014KN01491A (en) * | 2011-12-23 | 2015-10-23 | Lek Pharmaceuticals | |
IN2012MU03723A (en) * | 2012-12-31 | 2015-07-10 | Megafine Pharma P Ltd | |
CZ307217B6 (en) * | 2013-03-14 | 2018-04-04 | Zentiva, K.S. | An improved manufacturing process and new intermediates for synthesis of ticagrelor |
CN104098553B (en) * | 2013-04-10 | 2017-11-28 | 江苏恒瑞医药股份有限公司 | The preparation method of intermediate of ticagrelor and preparation method thereof and ticagrelor |
-
2013
- 2013-11-08 CZ CZ2013-866A patent/CZ2013866A3/en unknown
-
2014
- 2014-11-07 CN CN201480061207.8A patent/CN105940003A/en active Pending
- 2014-11-07 WO PCT/CZ2014/000131 patent/WO2015067230A1/en active Application Filing
- 2014-11-07 HU HU1600376A patent/HUP1600376A2/en unknown
Also Published As
Publication number | Publication date |
---|---|
CZ2013866A3 (en) | 2015-05-20 |
CN105940003A (en) | 2016-09-14 |
WO2015067230A1 (en) | 2015-05-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD9A | Lapse of provisional protection due to non-payment of fees |